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authorzsloan2022-10-11 23:28:09 +0000
committerzsloan2022-10-12 18:15:58 +0000
commit54baaec44b551a7b99c7629bd11663de26826514 (patch)
treefcad28595f849d6b04e2afca086393a7b56ddd9d /wqflask
parentf6c4b1350de14a778750b82fb423d3437d14a7d8 (diff)
downloadgenenetwork2-54baaec44b551a7b99c7629bd11663de26826514.tar.gz
Add filtering logic for correlation results
Diffstat (limited to 'wqflask')
-rw-r--r--wqflask/wqflask/correlation/show_corr_results.py46
1 files changed, 40 insertions, 6 deletions
diff --git a/wqflask/wqflask/correlation/show_corr_results.py b/wqflask/wqflask/correlation/show_corr_results.py
index 7623e18e..dfa48800 100644
--- a/wqflask/wqflask/correlation/show_corr_results.py
+++ b/wqflask/wqflask/correlation/show_corr_results.py
@@ -31,6 +31,7 @@ from wqflask.correlation.pre_computes import cache_new_traits_metadata
from utility.authentication_tools import check_resource_availability
from utility import hmac
+from utility.type_checking import get_float, get_int, get_string
def set_template_vars(start_vars, correlation_data):
@@ -51,6 +52,7 @@ def set_template_vars(start_vars, correlation_data):
target_dataset_ob = create_dataset(correlation_data['target_dataset'])
correlation_data['target_dataset'] = target_dataset_ob.as_dict()
correlation_data['table_json'] = correlation_json_for_table(
+ start_vars,
correlation_data,
correlation_data['this_trait'],
correlation_data['this_dataset'],
@@ -73,7 +75,7 @@ def set_template_vars(start_vars, correlation_data):
return correlation_data
-def correlation_json_for_table(correlation_data, this_trait, this_dataset, target_dataset_ob):
+def correlation_json_for_table(start_vars, correlation_data, this_trait, this_dataset, target_dataset_ob):
"""Return JSON data for use with the DataTable in the correlation result page
Keyword arguments:
@@ -93,6 +95,20 @@ def correlation_json_for_table(correlation_data, this_trait, this_dataset, targe
dataset_metadata = correlation_data["traits_metadata"]
+ min_expr = get_float(start_vars, 'min_expr')
+ p_range_lower = get_float(start_vars, 'p_range_lower', -1.0)
+ p_range_upper = get_float(start_vars, 'p_range_upper', 1.0)
+
+ if ('loc_chr' in start_vars and
+ 'min_loc_mb' in start_vars and
+ 'max_loc_mb' in start_vars):
+
+ location_chr = get_string(start_vars, 'loc_chr')
+ min_location_mb = get_int(start_vars, 'min_loc_mb')
+ max_location_mb = get_int(start_vars, 'max_loc_mb')
+ else:
+ location_chr = min_location_mb = max_location_mb = None
+
for i, trait_dict in enumerate(corr_results):
trait_name = list(trait_dict.keys())[0]
trait = trait_dict[trait_name]
@@ -104,14 +120,32 @@ def correlation_json_for_table(correlation_data, this_trait, this_dataset, targe
get_qtl_info=True)
target_trait = jsonable(target_trait_ob, target_dataset_ob)
new_traits_metadata[trait_name] = target_trait
- else:
- if target_dataset['type'] == "Publish":
- permissions = check_resource_availability(target_dataset_ob, trait_name)
- if permissions['metadata'] == "no-access":
+
+ if (float(trait.get('corr_coefficient',0.0)) >= p_range_lower and
+ float(trait.get('corr_coefficient',0.0)) <= p_range_upper):
+
+ if (target_dataset['type'] == "ProbeSet" or target_dataset['type'] == "Publish") and bool(target_trait['mean']):
+ if (min_expr != None) and (float(target_trait['mean']) < min_expr):
continue
- if target_trait['view'] == False:
+ if target_dataset['type'] == "ProbeSet" or target_dataset['type'] == "Geno":
+ if start_vars['location_type'] == "gene":
+ if location_chr != None and (target_trait['chr'] != location_chr):
+ continue
+ if (min_location_mb != None) and (float(target_trait['mb']) < float(min_location_mb)):
+ continue
+ if (max_location_mb != None) and (float(target_trait['mb']) > float(max_location_mb)):
+ continue
+ else:
+ if location_chr != None and (target_trait['lrs_chr'] != location_chr):
+ continue
+ if (min_location_mb != None) and (float(target_trait['lrs_mb']) < float(min_location_mb)):
+ continue
+ if (max_location_mb != None) and (float(target_trait['lrs_mb']) > float(max_location_mb)):
+ continue
+ else:
continue
+
results_dict = {}
results_dict['index'] = i + 1
results_dict['trait_id'] = target_trait['name']