aboutsummaryrefslogtreecommitdiff
path: root/wqflask/base
diff options
context:
space:
mode:
authorSam Ockman2012-05-24 02:18:20 -0400
committerSam Ockman2012-05-24 02:18:20 -0400
commit527bb0459cf488e5021696e326dc10d28ecdd74c (patch)
tree097e013d6a876fe0a6e178ff6defa813faa4af93 /wqflask/base
parentaa915612d2ff98f1e31d2ec38e8054382ef75dd9 (diff)
downloadgenenetwork2-527bb0459cf488e5021696e326dc10d28ecdd74c.tar.gz
Trying to get stuff working under new structure
Diffstat (limited to 'wqflask/base')
-rwxr-xr-xwqflask/base/GeneralObject.py71
-rw-r--r--wqflask/base/JinjaPage.py28
-rwxr-xr-xwqflask/base/__init__.py0
-rwxr-xr-xwqflask/base/admin.py88
-rwxr-xr-xwqflask/base/cgiData.py70
-rwxr-xr-xwqflask/base/cookieData.py52
-rwxr-xr-xwqflask/base/footer.py6
-rwxr-xr-xwqflask/base/header.py6
-rwxr-xr-xwqflask/base/indexBody.py290
-rwxr-xr-xwqflask/base/myCookie.py55
-rwxr-xr-xwqflask/base/sessionData.py53
-rwxr-xr-xwqflask/base/template.py123
-rwxr-xr-xwqflask/base/templatePage.py222
-rwxr-xr-xwqflask/base/webqtlCaseData.py54
-rwxr-xr-xwqflask/base/webqtlConfig.py73
-rwxr-xr-xwqflask/base/webqtlConfigLocal.py19
-rwxr-xr-xwqflask/base/webqtlDataset.py160
-rwxr-xr-xwqflask/base/webqtlFormData.py289
-rwxr-xr-xwqflask/base/webqtlTrait.py581
19 files changed, 2240 insertions, 0 deletions
diff --git a/wqflask/base/GeneralObject.py b/wqflask/base/GeneralObject.py
new file mode 100755
index 00000000..311c9e22
--- /dev/null
+++ b/wqflask/base/GeneralObject.py
@@ -0,0 +1,71 @@
+# Copyright (C) University of Tennessee Health Science Center, Memphis, TN.
+#
+# This program is free software: you can redistribute it and/or modify it
+# under the terms of the GNU Affero General Public License
+# as published by the Free Software Foundation, either version 3 of the
+# License, or (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
+# See the GNU Affero General Public License for more details.
+#
+# This program is available from Source Forge: at GeneNetwork Project
+# (sourceforge.net/projects/genenetwork/).
+#
+# Contact Drs. Robert W. Williams and Xiaodong Zhou (2010)
+# at rwilliams@uthsc.edu and xzhou15@uthsc.edu
+#
+#
+#
+# This module is used by GeneNetwork project (www.genenetwork.org)
+#
+# Created by GeneNetwork Core Team 2010/08/10
+#
+# Last updated by GeneNetwork Core Team 2010/10/20
+
+class GeneralObject:
+ """
+ Base class to define an Object.
+ a = [Spam(1, 4), Spam(9, 3), Spam(4,6)]
+ a.sort(lambda x, y: cmp(x.eggs, y.eggs))
+ """
+
+ def __init__(self, *args, **kw):
+ self.contents = list(args)
+ for name, value in kw.items():
+ setattr(self, name, value)
+
+ def __setitem__(self, key, value):
+ setattr(self, key, value)
+
+ def __getitem__(self, key):
+ return getattr(self, key)
+
+ def __getattr__(self, key):
+ if key in self.__dict__.keys():
+ return self.__dict__[key]
+ else:
+ return eval("self.__dict__.%s" % key)
+
+ def __len__(self):
+ return len(self.__dict__) - 1
+
+ def __str__(self):
+ s = ''
+ for key in self.__dict__.keys():
+ if key != 'contents':
+ s += '%s = %s\n' % (key,self.__dict__[key])
+ return s
+
+ def __repr__(self):
+ s = ''
+ for key in self.__dict__.keys():
+ s += '%s = %s\n' % (key,self.__dict__[key])
+ return s
+
+ def __cmp__(self,other):
+ return len(self.__dict__.keys()).__cmp__(len(other.__dict__.keys()))
+
+
+
diff --git a/wqflask/base/JinjaPage.py b/wqflask/base/JinjaPage.py
new file mode 100644
index 00000000..07e485b1
--- /dev/null
+++ b/wqflask/base/JinjaPage.py
@@ -0,0 +1,28 @@
+import logging
+logging.basicConfig(filename="/tmp/gn_log", level=logging.INFO)
+_log = logging.getLogger("search")
+
+from pprint import pformat as pf
+
+import templatePage
+
+from utility import formatting
+
+import jinja2
+JinjaEnv = jinja2.Environment(loader=jinja2.FileSystemLoader('/gnshare/gn/web/webqtl/templates'))
+JinjaEnv.globals['numify'] = formatting.numify
+
+
+class JinjaPage(templatePage.templatePage):
+ """Class derived from our regular templatePage, but uses Jinja2 instead.
+
+ When converting pages from Python generated templates, change the base class from templatePage
+ to JinjaPage
+
+ """
+
+
+ def write(self):
+ """We override the base template write so we can use Jinja2."""
+ _log.info(pf(self.__dict__))
+ return self.jtemplate.render(**self.__dict__)
diff --git a/wqflask/base/__init__.py b/wqflask/base/__init__.py
new file mode 100755
index 00000000..e69de29b
--- /dev/null
+++ b/wqflask/base/__init__.py
diff --git a/wqflask/base/admin.py b/wqflask/base/admin.py
new file mode 100755
index 00000000..a04df2da
--- /dev/null
+++ b/wqflask/base/admin.py
@@ -0,0 +1,88 @@
+# Copyright (C) University of Tennessee Health Science Center, Memphis, TN.
+#
+# This program is free software: you can redistribute it and/or modify it
+# under the terms of the GNU Affero General Public License
+# as published by the Free Software Foundation, either version 3 of the
+# License, or (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
+# See the GNU Affero General Public License for more details.
+#
+# This program is available from Source Forge: at GeneNetwork Project
+# (sourceforge.net/projects/genenetwork/).
+#
+# Contact Drs. Robert W. Williams and Xiaodong Zhou (2010)
+# at rwilliams@uthsc.edu and xzhou15@uthsc.edu
+#
+#
+#
+# This module is used by GeneNetwork project (www.genenetwork.org)
+#
+# Created by GeneNetwork Core Team 2010/08/10
+#
+# Last updated by GeneNetwork Core Team 2010/10/20
+
+
+
+
+
+#XZ, 04/02/2009: we should put this into database.
+
+
+###LIST of databases used into gene name query
+
+
+ADMIN_search_dbs = {
+ 'rat': {'PERITONEAL FAT': ['FT_2A_0605_Rz'],
+ 'KIDNEY': ['KI_2A_0405_Rz'],
+ 'ADRENAL GLAND': ['HXB_Adrenal_1208'],
+ 'HEART': ['HXB_Heart_1208']
+ },
+ 'mouse': {'CEREBELLUM': ['CB_M_0305_R'],
+ 'STRIATUM': ['SA_M2_0905_R', 'SA_M2_0405_RC', 'UTHSC_1107_RankInv', 'Striatum_Exon_0209'],
+ 'HIPPOCAMPUS': ['HC_M2_0606_R', 'UMUTAffyExon_0209_RMA'],
+ 'WHOLE BRAIN': ['BR_M2_1106_R', 'IBR_M_0106_R', 'BRF2_M_0805_R', 'UCLA_BHF2_BRAIN_0605'],
+ 'LIVER': ['LV_G_0106_B', 'UCLA_BHF2_LIVER_0605'],
+ 'EYE': ['Eye_M2_0908_R'],
+ 'HEMATOPOIETIC STEM CELLS': ['HC_U_0304_R'],
+ 'KIDNEY': ['MA_M2_0806_R'],
+ 'MAMMARY TUMORS': ['MA_M_0704_R', 'NCI_Agil_Mam_Tum_RMA_0409'],
+ 'PREFRONTAL CORTEX': ['VCUSal_1206_R'],
+ 'SPLEEN': ['IoP_SPL_RMA_0509'],
+ 'NUCLEUS ACCUMBENS': ['VCUSalo_1007_R'],
+ 'NEOCORTEX': ['HQFNeoc_0208_RankInv'],
+ 'ADIPOSE': ['UCLA_BHF2_ADIPOSE_0605'],
+ 'RETINA': ['Illum_Retina_BXD_RankInv0410']
+ },
+ 'human': {
+ 'LYMPHOBLAST B CELL': ['Human_1008', 'UT_CEPH_RankInv0909'],
+ 'WHOLE BRAIN': ['GSE5281_F_RMA0709', 'GSE15222_F_RI_0409']
+ }
+ }
+
+
+###LIST of tissue alias
+
+ADMIN_tissue_alias = {'CEREBELLUM': ['Cb'],
+ 'STRIATUM': ['Str'],
+ 'HIPPOCAMPUS': ['Hip'],
+ 'WHOLE BRAIN': ['Brn'],
+ 'LIVER': ['Liv'],
+ 'EYE': ['Eye'],
+ 'PERITONEAL FAT': ['Fat'],
+ 'HEMATOPOIETIC STEM CELLS': ['Hsc'],
+ 'KIDNEY': ['Kid'],
+ 'ADRENAL GLAND': ['Adr'],
+ 'HEART': ['Hea'],
+ 'MAMMARY TUMORS': ['Mam'],
+ 'PREFRONTAL CORTEX': ['Pfc'],
+ 'SPLEEN': ['Spl'],
+ 'NUCLEUS ACCUMBENS': ['Nac'],
+ 'NEOCORTEX': ['Ctx'],
+ 'ADIPOSE': ['Wfat'],
+ 'RETINA': ['Ret']
+ }
+
+
diff --git a/wqflask/base/cgiData.py b/wqflask/base/cgiData.py
new file mode 100755
index 00000000..57416060
--- /dev/null
+++ b/wqflask/base/cgiData.py
@@ -0,0 +1,70 @@
+# Copyright (C) University of Tennessee Health Science Center, Memphis, TN.
+#
+# This program is free software: you can redistribute it and/or modify it
+# under the terms of the GNU Affero General Public License
+# as published by the Free Software Foundation, either version 3 of the
+# License, or (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
+# See the GNU Affero General Public License for more details.
+#
+# This program is available from Source Forge: at GeneNetwork Project
+# (sourceforge.net/projects/genenetwork/).
+#
+# Contact Drs. Robert W. Williams and Xiaodong Zhou (2010)
+# at rwilliams@uthsc.edu and xzhou15@uthsc.edu
+#
+#
+#
+# This module is used by GeneNetwork project (www.genenetwork.org)
+#
+# Created by GeneNetwork Core Team 2010/08/10
+#
+# Last updated by GeneNetwork Core Team 2010/10/20
+
+#########################################
+#convert Field storage object to Dict object
+#in order to be able to saved into a session file
+#########################################
+
+class cgiData(dict):
+ '''convert Field storage object to Dict object
+ Filed storage object cannot be properly dumped
+ '''
+
+ def __init__(self, field_storage=None):
+
+ if not field_storage:
+ field_storage={}
+
+ for key in field_storage.keys():
+ temp = field_storage.getlist(key)
+ if len(temp) > 1:
+ temp = map(self.toValue, temp)
+ elif len(temp) == 1:
+ temp = self.toValue(temp[0])
+ else:
+ temp = None
+ self[key]= temp
+
+ def toValue(self, obj):
+ '''fieldstorge returns different type of objects, \
+ need to convert to string or None'''
+ try:
+ return obj.value
+ except:
+ return ""
+
+ def getvalue(self, k, default= None):
+ try:
+ return self[k]
+ except:
+ return default
+
+ getfirst = getvalue
+
+
+
+
diff --git a/wqflask/base/cookieData.py b/wqflask/base/cookieData.py
new file mode 100755
index 00000000..4b7c9046
--- /dev/null
+++ b/wqflask/base/cookieData.py
@@ -0,0 +1,52 @@
+# Copyright (C) University of Tennessee Health Science Center, Memphis, TN.
+#
+# This program is free software: you can redistribute it and/or modify it
+# under the terms of the GNU Affero General Public License
+# as published by the Free Software Foundation, either version 3 of the
+# License, or (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
+# See the GNU Affero General Public License for more details.
+#
+# This program is available from Source Forge: at GeneNetwork Project
+# (sourceforge.net/projects/genenetwork/).
+#
+# Contact Drs. Robert W. Williams and Xiaodong Zhou (2010)
+# at rwilliams@uthsc.edu and xzhou15@uthsc.edu
+#
+#
+#
+# This module is used by GeneNetwork project (www.genenetwork.org)
+#
+# Created by GeneNetwork Core Team 2010/08/10
+#
+# Last updated by GeneNetwork Core Team 2010/10/20
+
+#########################################
+#convert mod_python object to Dict object
+#in order to be able to be pickled
+#########################################
+
+class cookieData(dict):
+ 'convert mod python Cookie object to Dict object'
+
+ def __init__(self, cookies=None):
+
+ if not cookies:
+ cookies={}
+
+ for key in cookies.keys():
+ self[key.lower()]= cookies[key].value
+
+ def getvalue(self, k, default= None):
+ try:
+ return self[k.lower()]
+ except:
+ return default
+
+ getfirst = getvalue
+
+
+
diff --git a/wqflask/base/footer.py b/wqflask/base/footer.py
new file mode 100755
index 00000000..6f92fdf8
--- /dev/null
+++ b/wqflask/base/footer.py
@@ -0,0 +1,6 @@
+import webqtlConfig
+
+footer_html = open(webqtlConfig.HTMLPATH + 'footer.html', 'r').read()
+footer = footer_html.replace('%"','%%"')
+
+footer_string = footer.replace('<!-- %s -->', '%s')
diff --git a/wqflask/base/header.py b/wqflask/base/header.py
new file mode 100755
index 00000000..b6136b51
--- /dev/null
+++ b/wqflask/base/header.py
@@ -0,0 +1,6 @@
+import webqtlConfig
+
+header_string = open(webqtlConfig.HTMLPATH + 'header.html', 'r').read()
+header_string = header_string.replace("\\'", "'")
+header_string = header_string.replace('%"','%%"')
+header_string = header_string.replace('<!-- %s -->', '%s') \ No newline at end of file
diff --git a/wqflask/base/indexBody.py b/wqflask/base/indexBody.py
new file mode 100755
index 00000000..aa67dffa
--- /dev/null
+++ b/wqflask/base/indexBody.py
@@ -0,0 +1,290 @@
+index_body_string = """
+<TD vAlign=top width="40%" align="left" height=10 bgColor=#eeeeee>
+ <p style="font-size:18px;font-family:verdana;color:black"><B> Select and Search</B>
+ <Form METHOD="POST" ACTION="/webqtl/main.py" ENCTYPE="multipart/form-data" NAME="SEARCHFORM">
+
+ <TABLE width="100%">
+
+ <!-- SPECIES SELECTION -->
+ <TR>
+ <TD align=right height="35" style="font-size:14px;font-family:verdana;color:black" width="16%">
+ <B>Species:</B>
+ </TD>
+
+ <TD width="3%">
+ </TD>
+
+ <TD NOWRAP width="85%" align="left">
+ <DIV Id="menu0">
+ <Select NAME="species" size=1 id="species" onchange="fillOptions('species');">
+ </Select>
+ </DIV>
+ </TD>
+ </TR>
+
+ <!-- GROUP SELECTION -->
+
+ <TR>
+
+ <TD align="right" height="35" style="font-size:14px;font-family:verdana;color:black">
+ <B>Group:</B>
+ </TD>
+
+ <TD width="3%">
+ </TD>
+
+ <TD NOWRAP width="85%" align="left">
+ <DIV Id="menu1">
+
+ <Select NAME="cross" size=1 id="cross" onchange="fillOptions('cross');">
+ </Select>
+ <input type="button" class="button" value=" Info " onCLick="javascript:crossinfo();">
+ </DIV>
+ </TD>
+ </TR>
+
+
+ <!-- TYPE SELECTION -->
+
+ <TR>
+
+ <TD align=right height=35 style="font-size:14px;font-family:verdana;color:black">
+ <B>Type:</B>
+ </TD>
+
+ <TD width="3%">
+ </TD>
+ <TD NOWRAP width="85%" align="left">
+ <DIV Id="menu2">
+ <Select NAME="tissue" size=1 id="tissue" onchange="fillOptions('tissue');">
+
+ </Select>
+ </DIV>
+ </TD>
+ </TR>
+
+
+ <!-- DATABASE SELECTION -->
+ <TR>
+ <TD align=right height=35 style="font-size:14px;font-family:verdana;color:black">
+ <B>Database:</B>
+ </TD>
+
+ <TD width="3%">
+ </TD>
+
+ <TD NOWRAP width="85%" align="left">
+ <DIV Id="menu3">
+ <Select NAME="database" size=1 id="database">
+ </Select>
+ <input type="button" class="button" value=" Info " onCLick="javascript:databaseinfo();">
+ </DIV>
+
+ </TD>
+ </TR>
+
+ <!-- USER HELP -->
+ <TR>
+ <TD align=right height=20 width="10%">
+ </TD>
+ <TD width="3%">
+ </TD>
+
+ <TD align="left" width="85%">
+ <P class="fs12">&nbsp;&nbsp;&nbsp;&nbsp;Databases marked with <B>**</B> suffix are not public yet.
+ <BR>&nbsp;&nbsp;&nbsp;&nbsp;Access requires <A HREF="/account.html" target="_blank" class="fs14"><small>user login</small></A>.</P>
+ </TD>
+ </TR>
+
+
+<!-- GET ANY SEARCH -->
+ <TR>
+ <TD align=right height=35 NOWRAP="on" style="font-size:14px;font-family:verdana;color:black" width="10%">
+ <B>Get Any:</B>
+ </TD>
+
+ <TD width="3%">
+ </TD>
+
+ <TD NOWRAP width="85%" align="left">
+
+ <input id="tfor" name="ORkeyword" style="width:420px; background-color:white; font-family:verdana; font-size:14px" type="text" maxlength="500">
+ </TD>
+ </TR>
+
+
+
+<!-- GET ANY HELP -->
+ <TR>
+ <TD align=right height=20 width="10%">
+ </TD>
+ <TD width="3%">
+
+ </TD>
+ <TD width="85%" align="left">
+ <P class="fs12">&nbsp;&nbsp;&nbsp;&nbsp;Enter terms, genes, ID numbers in the <B>Get Any</B> field.
+ <BR>&nbsp;&nbsp;&nbsp;&nbsp;Use <B>*</B> or <B>?</B> wildcards (Cyp*a?, synap*).
+ <BR>&nbsp;&nbsp;&nbsp;&nbsp;Use <B>Combined</B> for terms such as <I>tyrosine kinase</I>.</P>
+
+ </TD>
+ </TR>
+
+
+
+<!-- COMBINED SEARCH -->
+
+ <TR>
+ <TD align=right height=35 NOWRAP="on" STYLE="font-size:14px;font-family:verdana;color:black" width="10%">
+ <B>Combined:</B>
+ </TD>
+
+ <TD width="3%">
+ </TD>
+
+ <TD NOWRAP width="85%" align="left">
+ <input id="tfand" NAME="ANDkeyword" STYLE="width:420px; background-color:white; font-family:verdana; font-size:14px" type="text" maxlength="500">
+ <input name="matchwhole" type="hidden" value="ON">
+ </TD>
+ </TR>
+
+
+
+<!-- SEARCH, MAKE DEFAULT, ADVANCED SEARCH -->
+
+ <TR ALIGN="center">
+ <TD width="3%">
+ </TD>
+ <TD width="3%">
+ </TD>
+ <TD ALIGN="left" HEIGHT="40" COLSPAN=3>
+ <INPUT id="btsearch" TYPE="Submit" CLASS="button" STYLE="font-size:12px" VALUE=" Search ">&nbsp;&nbsp;&nbsp;&nbsp;
+ <INPUT TYPE="button" CLASS="button" STYLE="font-size:12px" VALUE=" Make Default " onClick = "setDefault(this.form);">&nbsp;&nbsp;&nbsp;&nbsp;
+ <INPUT TYPE="button" CLASS="button" STYLE="font-size:12px" VALUE=" Advanced Search " onClick="javascript:window.open('/index3.html', '_self');">
+
+ </TD>
+ </TR>
+ </TABLE>
+ <INPUT TYPE="hidden" NAME="FormID" VALUE="searchResult">
+ <INPUT TYPE="hidden" NAME="RISet" VALUE="BXD">
+ <SCRIPT SRC="/javascript/selectDatasetMenu.js"></SCRIPT>
+ </FORM>
+ </CENTER>
+
+
+
+
+
+<!-- QUICK HELP -->
+
+<P><LEFT>&nbsp;______________________________________________________
+
+<P STYLE="font-size:13px;font-family:verdana;color:black"><B>&nbsp;
+
+Quick HELP Examples and </B>
+<A HREF="http://www.genenetwork.org/index4.html" target="_blank" class="fs14"><B>
+ User's Guide</B></A></P>
+
+</CENTER style="font-size:12px;font-family:verdana;color:black">
+&nbsp;&nbsp;You can also use advanced commands. Copy these simple examples
+<BR>&nbsp;&nbsp;into the <B>Get Any</B> or <B>Combined</B> search fields:
+<UL style="font-size:12px;font-family:verdana;color:black">
+
+<LI><B><I>POSITION=(chr1 25 30)</I></B> finds genes, markers, or transcripts on chromosome 1 between 25 and 30 Mb.
+
+<LI><B><I>MEAN=(15 16) LRS=(23 46)</I></B> in the <B>Combined</B> field finds highly expressed genes (15 to 16 log2 units) AND with peak <A HREF="http://www.genenetwork.org/glossary.html#L" target="_blank" class="fs14"><small>LRS</small></A> linkage between 23 and 46.
+
+
+<LI><B><I>RIF=mitochondrial</I></B> searches RNA databases for <A HREF="http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html" target="_blank" class="fs14"><small>GeneRIF</small></A> links.
+
+<LI><B><I>WIKI=nicotine</I></B> searches <A HREF="http://www.genenetwork.org/webqtl/main.py?FormID=geneWiki" target="_blank" class="fs14"><small>GeneWiki</small></A> for genes that you or other users have annotated with the word <I>nicotine</I>.
+
+<LI><B><I>GO:0045202</I></B> searches for synapse-associated genes listed in the <A HREF="http://www.godatabase.org/cgi-bin/amigo/go.cgi" target="_blank" class="fs14"><small>Gene Ontology</small></A>.
+
+
+<LI><B><I>GO:0045202 LRS=(9 99 Chr4 122 155) cisLRS=(9 999 10)</I> </B><BR> in <B>Combined</B> finds synapse-associated genes with <A HREF="http://www.genenetwork.org/glossary.html#E" target="_blank" class="fs14"><small>cis eQTL</small></A> on Chr 4 from 122 and 155 Mb with LRS scores between 9 and 999.
+
+<LI><B><I>RIF=diabetes LRS=(9 999 Chr2 100 105) transLRS=(9 999 10)</I> </B><BR> in <B>Combined</B> finds diabetes-associated transcripts with peak <A HREF="http://www.genenetwork.org/glossary.html#E" target="_blank" class="fs14"><small>trans eQTLs</small></A> on Chr 2 between 100 and 105 Mb with LRS scores between 9 and 999.
+
+
+</UL>
+</DIR>
+ </TD>
+<!-- END OF FIND SELECTOR PULL-DOWN PANEL (LEFT SIDE) -->
+
+<!-- START OF TOP RIGHT PANEL -->
+
+<TD vAlign=top width="40%" bgColor=#FFFFFF>
+ <p style="font-size:15px;font-family:verdana;color:black"><B>Websites Affiliated with GeneNetwork</B></p>
+ <p style="font-size:12px;font-family:verdana;color:black">
+ <ul>
+ <li><a href="http://ucscbrowser.genenetwork.org/" target="_blank">Genome Browser</a> at UTHSC</li>
+ <li><a href="http://galaxy.genenetwork.org/" target="_blank">Galaxy</a> at UTHSC</li>
+ <li>GeneNetwork at <a href="http://ec2.genenetwork.org/" target="_blank">Amazon Cloud (EC2)</a></li>
+ <li>GeneNetwork Source Codes at <a href="http://sourceforge.net/projects/genenetwork/" target="_blank">SourceForge</a></li>
+ </ul>
+ </p>
+ <P>____________________________
+
+ <p style="font-size:15px;font-family:verdana;color:black"><B>Getting Started</B> &nbsp;&nbsp; </p>
+ <OL style="font-size:12px;font-family:verdana;color:black">
+ <LI>Select <B>Species</B> (or select All)
+ <LI>Select <B>Group</B> (a specific sample)
+ <LI>Select <B>Type</B> of data:
+ <UL>
+ <LI>Phenotype (traits)
+ <LI>Genotype (markers)
+ <LI>Expression (mRNAs)
+ </UL>
+ <LI>Select a <B>Database</B>
+ <LI>Enter search terms in the <B>Get Any</B> or <B>Combined</B> field: words, genes, ID numbers, probes, advanced search commands
+ <LI>Click on the <B>Search</B> button
+ <LI>Optional: Use the <B>Make Default</B> button to save your preferences
+ </OL>
+
+ <P>____________________________
+
+<p style="font-size:14px;font-family:verdana;color:black"><B>How to Use GeneNetwork</B>
+
+ <BLOCKQUOTE>
+ <p style="font-size:12px;font-family:verdana;color:black">Take a 20-40 minute GeneNetwork <A HREF="http://www.genenetwork.org/tutorial/WebQTLTour/" target="_blank" class="fs14"><small>Tour</small></A> that includes screen shots and typical steps in the analysis.</P>
+ </BLOCKQUOTE>
+ <BLOCKQUOTE>
+ <p style="font-size:12px;font-family:verdana;color:black">For information about resources and methods, select the <img src="http://www.genenetwork.org/images/upload/Info.png" alt="INFO" border= 0 valign="middle"> buttons.</P>
+
+
+
+<p style="font-size:12px;font-family:verdana;color:black">Try the <A HREF="http://alexandria.uthsc.edu/" target="_blank" class="fs14"><small>Workstation</small></A> site to explore data and features that are being implemented.</P>
+
+
+<p style="font-size:12px;font-family:verdana;color:black">Review the <A HREF="/conditionsofUse.html" target="_blank" class="fs14"><small>Conditions</small></A> and <A HREF="/statusandContact.html" target="_blank" class="fs14"><small>Contacts</small></A> pages for information on the status of data sets and advice on their use and citation.</P>
+
+
+ </BLOCKQUOTE>
+
+
+
+ <p style="font-size:14px;font-family:verdana;color:black"><B>Mirror and Development Sites</B></P>
+
+ <UL>
+ <LI><A HREF="http://www.genenetwork.org/" target="_blank" style="font-size:12px;font-family:verdana;color:blue">Main GN site at UTHSC</A> (main site)
+ <LI><A HREF="http://www.genenetwork.waimr.uwa.edu.au/" target="_blank" style="font-size:12px;font-family:verdana;color:blue">Australia at the UWA</A>
+ <LI><A HREF="http://gn.genetics.ucla.edu/" target="_blank" style="font-size:12px;font-family:verdana;color:blue">California at UCLA</A>
+ <LI><A HREF="http://genenetwork.helmholtz-hzi.de/" target="_blank" style="font-size:12px;font-family:verdana;color:blue">Germany at the HZI</A>
+ <LI><A HREF="https://genenetwork.hubrecht.eu/" target="_blank" style="font-size:12px;font-family:verdana;color:blue">Netherlands at the Hubrecht</A> (Development)
+ <LI><A HREF="http://xzhou3.memphis.edu/" target="_blank" style="font-size:12px;font-family:verdana;color:blue">Memphis at the U of M</A>
+ <LI><A HREF="http://webqtl.bic.nus.edu.sg/" target="_blank" style="font-size:12px;font-family:verdana;color:blue">Singapore at the NUS</A>
+ <LI><A HREF="http://genenetwork.epfl.ch/" target="_blank" style="font-size:12px;font-family:verdana;color:blue">Switzerland at the EPFL</A>
+ </UL>
+
+
+ <p style="font-size:14px;font-family:verdana;color:black"><B>History and Archive</B>
+
+ <BLOCKQUOTE>
+ <p style="font-size:12px;font-family:verdana;color:black">GeneNetwork's <A HREF="http://artemis.uthsc.edu" target="_blank" class="fs14"><small>Time Machine</small></A> links to earlier versions that correspond to specific publication dates.</P>
+
+ </BLOCKQUOTE>
+
+
+</P>
+ </TD>
+"""
diff --git a/wqflask/base/myCookie.py b/wqflask/base/myCookie.py
new file mode 100755
index 00000000..db5320df
--- /dev/null
+++ b/wqflask/base/myCookie.py
@@ -0,0 +1,55 @@
+# Copyright (C) University of Tennessee Health Science Center, Memphis, TN.
+#
+# This program is free software: you can redistribute it and/or modify it
+# under the terms of the GNU Affero General Public License
+# as published by the Free Software Foundation, either version 3 of the
+# License, or (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
+# See the GNU Affero General Public License for more details.
+#
+# This program is available from Source Forge: at GeneNetwork Project
+# (sourceforge.net/projects/genenetwork/).
+#
+# Contact Drs. Robert W. Williams and Xiaodong Zhou (2010)
+# at rwilliams@uthsc.edu and xzhou15@uthsc.edu
+#
+#
+#
+# This module is used by GeneNetwork project (www.genenetwork.org)
+#
+# Created by GeneNetwork Core Team 2010/08/10
+#
+# Last updated by GeneNetwork Core Team 2010/10/20
+
+#########################################
+## python cookie and mod python cookie are
+## not compatible
+#########################################
+
+class myCookie(dict):
+ 'define my own cookie'
+
+ def __init__(self, name="", value="", expire = None, path="/"):
+ self['name']= name
+ self['value']= value
+ self['expire']= expire
+ self['path']= path
+
+ def __getattr__(self, key):
+ if key in self.keys():
+ return self[key]
+ else:
+ return None
+
+ def __nonzero__ (self):
+ if self['name']:
+ return 1
+ else:
+ return 0
+
+
+
+
diff --git a/wqflask/base/sessionData.py b/wqflask/base/sessionData.py
new file mode 100755
index 00000000..01555f87
--- /dev/null
+++ b/wqflask/base/sessionData.py
@@ -0,0 +1,53 @@
+# Copyright (C) University of Tennessee Health Science Center, Memphis, TN.
+#
+# This program is free software: you can redistribute it and/or modify it
+# under the terms of the GNU Affero General Public License
+# as published by the Free Software Foundation, either version 3 of the
+# License, or (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
+# See the GNU Affero General Public License for more details.
+#
+# This program is available from Source Forge: at GeneNetwork Project
+# (sourceforge.net/projects/genenetwork/).
+#
+# Contact Drs. Robert W. Williams and Xiaodong Zhou (2010)
+# at rwilliams@uthsc.edu and xzhou15@uthsc.edu
+#
+#
+#
+# This module is used by GeneNetwork project (www.genenetwork.org)
+#
+# Created by GeneNetwork Core Team 2010/08/10
+#
+# Last updated by GeneNetwork Core Team 2010/10/20
+
+#########################################
+#convert mod_python object to Dict object
+#in order to be able to be pickled
+#########################################
+
+class sessionData(dict):
+ 'convert mod python Session object to Dict object'
+
+ def __init__(self, mod_python_session=None):
+
+ if not mod_python_session:
+ mod_python_session = {}
+
+ for key in mod_python_session.keys():
+ self[key]= mod_python_session[key]
+
+
+ def getvalue(self, k, default= None):
+ try:
+ return self[k]
+ except:
+ return default
+
+ getfirst = getvalue
+
+
+
diff --git a/wqflask/base/template.py b/wqflask/base/template.py
new file mode 100755
index 00000000..85bd86df
--- /dev/null
+++ b/wqflask/base/template.py
@@ -0,0 +1,123 @@
+# Copyright (C) University of Tennessee Health Science Center, Memphis, TN.
+#
+# This program is free software: you can redistribute it and/or modify it
+# under the terms of the GNU Affero General Public License
+# as published by the Free Software Foundation, either version 3 of the
+# License, or (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
+# See the GNU Affero General Public License for more details.
+#
+# This program is available from Source Forge: at GeneNetwork Project
+# (sourceforge.net/projects/genenetwork/).
+#
+# Contact Drs. Robert W. Williams and Xiaodong Zhou (2010)
+# at rwilliams@uthsc.edu and xzhou15@uthsc.edu
+#
+#
+#
+# This module is used by GeneNetwork project (www.genenetwork.org)
+#
+# Created by GeneNetwork Core Team 2010/08/10
+#
+# Last updated by GeneNetwork Core Team 2010/10/20
+
+template = """
+<?XML VERSION="1.0" ENCODING="UTF-8">
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN">
+<HTML>
+<HEAD>
+<TITLE>%s</TITLE>
+
+<META http-equiv=Content-Type content="text/html; charset=iso-8859-1">
+<META NAME="keywords" CONTENT="genetics, bioinformatics, genome, phenome, gene expression, complex trait analysis, gene mapping, SNP, quantitative trait locus QTL, expression eQTL, WebQTL, Traitnet, Traitnetwork, personalized medicine">
+<META NAME="description" CONTENT ="GeneNetwork is a free scientific web resource used to study relationships between differences in genes, environmental factors, phenotypes, and disease risk." >
+<META NAME="author" CONTENT ="GeneNetwork developers" >
+<META NAME="geo.placename" CONTENT ="Memphis, TN" >
+<META NAME="geo.region" CONTENT="US-TN">
+%s
+<LINK REL="stylesheet" TYPE="text/css" HREF='/css/general.css'>
+<LINK REL="stylesheet" TYPE="text/css" HREF='/css/menu.css'>
+<link rel="stylesheet" media="all" type="text/css" href="/css/tabbed_pages.css" />
+<LINK REL="apple-touch-icon" href="/images/ipad_icon3.png" />
+<link type="text/css" href='/css/custom-theme/jquery-ui-1.8.12.custom.css' rel='Stylesheet' />
+<link type="text/css" href='/css/tab_style.css' rel='Stylesheet' />
+
+<script type="text/javascript" src="/javascript/jquery-1.5.2.min.js"></script>
+<SCRIPT SRC="/javascript/webqtl.js"></SCRIPT>
+<SCRIPT SRC="/javascript/dhtml.js"></SCRIPT>
+<SCRIPT SRC="/javascript/tablesorter.js"></SCRIPT>
+<SCRIPT SRC="/javascript/jqueryFunction.js"></SCRIPT>
+<script src="/javascript/tabbed_pages.js" type="text/javascript"></script>
+<script src="/javascript/jquery-ui-1.8.12.custom.min.js" type="text/javascript"></script>
+%s
+
+<script type="text/javascript">
+ var _gaq = _gaq || [];
+ _gaq.push(['_setAccount', 'UA-3782271-1']);
+ _gaq.push(['_trackPageview']);
+ (function() {
+ var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true;
+ ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js';
+ var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s);
+ })();
+</script>
+</HEAD>
+<BODY bottommargin="2" leftmargin="2" rightmargin="2" topmargin="2" text=#000000 bgColor=#ffffff %s>
+%s
+<TABLE cellSpacing=5 cellPadding=4 width="100%%" border=0>
+ <TBODY>
+ <!-- Start of header -->
+ <TR>
+ %s
+ </TR>
+ <!-- End of header -->
+
+ <!-- Start of body -->
+ <TR>
+ <TD bgColor=#eeeeee class="solidBorder">
+ <Table width= "100%%" cellSpacing=0 cellPadding=5>
+ <TR>
+ %s
+ </TR>
+ </TABLE>
+ </TD>
+ </TR>
+ <!-- End of body -->
+
+ <!-- Start of footer -->
+ <TR>
+ <TD align=center bgColor=#ddddff class="solidBorder">
+ <TABLE width="90%%">%s</table>
+ </td>
+ </TR>
+ <!-- End of footer -->
+</TABLE>
+
+<!-- menu script itself. you should not modify this file -->
+<script language="JavaScript" src="/javascript/menu_new.js"></script>
+<!-- items structure. menu hierarchy and links are stored there -->
+<script language="JavaScript" src="/javascript/menu_items.js"></script>
+<!-- files with geometry and styles structures -->
+<script language="JavaScript" src="/javascript/menu_tpl.js"></script>
+<script language="JavaScript">
+ <!--//
+ // Note where menu initialization block is located in HTML document.
+ // Don't try to position menu locating menu initialization block in
+ // some table cell or other HTML element. Always put it before </body>
+ // each menu gets two parameters (see demo files)
+ // 1. items structure
+ // 2. geometry structure
+ new menu (MENU_ITEMS, MENU_POS);
+ // make sure files containing definitions for these variables are linked to the document
+ // if you got some javascript error like "MENU_POS is not defined", then you've made syntax
+ // error in menu_tpl.js file or that file isn't linked properly.
+
+ // also take a look at stylesheets loaded in header in order to set styles
+ //-->
+</script>
+</BODY>
+</HTML>
+"""
diff --git a/wqflask/base/templatePage.py b/wqflask/base/templatePage.py
new file mode 100755
index 00000000..4dece24a
--- /dev/null
+++ b/wqflask/base/templatePage.py
@@ -0,0 +1,222 @@
+# Copyright (C) University of Tennessee Health Science Center, Memphis, TN.
+#
+# This program is free software: you can redistribute it and/or modify it
+# under the terms of the GNU Affero General Public License
+# as published by the Free Software Foundation, either version 3 of the
+# License, or (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
+# See the GNU Affero General Public License for more details.
+#
+# This program is available from Source Forge: at GeneNetwork Project
+# (sourceforge.net/projects/genenetwork/).
+#
+# Contact Drs. Robert W. Williams and Xiaodong Zhou (2010)
+# at rwilliams@uthsc.edu and xzhou15@uthsc.edu
+#
+#
+#
+# This module is used by GeneNetwork project (www.genenetwork.org)
+#
+# Created by GeneNetwork Core Team 2010/08/10
+#
+# Last updated by GeneNetwork Core Team 2010/10/20
+
+#templatePage.py
+#
+#--Genenetwork generates a lot of pages; this file is the generic version of them, defining routines they all use.
+#
+#Classes:
+#templatePage
+#
+#Functions (of templatePage):
+#__init__(...) -- class constructor, allows a more specific template to be used in addition to templatePage
+#__str__(self) -- returns the object's elements as a tuple
+#__del__(self) -- closes the current connection to MySQL, if there is one
+#write -- explained below
+#writefile -- explained below
+#openMysql(self) -- opens a MySQL connection and stores the resulting cursor in the object's cursor variable
+#updMysql(self) -- same as openMysql
+#error -- explained below
+#session -- explained below
+
+
+import socket
+import time
+import shutil
+import MySQLdb
+import os
+
+from htmlgen import HTMLgen2 as HT
+
+import template
+import webqtlConfig
+import header
+import footer
+from utility import webqtlUtil
+
+
+
+class templatePage:
+
+ contents = ['title','basehref','js1','js2', 'layer', 'header', 'body', 'footer']
+
+ # you can pass in another template here if you want
+ def __init__(self, fd=None, template=template.template):
+
+ # initiate dictionary
+ self.starttime = time.time()
+ self.dict = {}
+ self.template = template
+
+ for item in self.contents:
+ self.dict[item] = ""
+
+ self.dict['basehref'] = "" #webqtlConfig.BASEHREF
+ self.cursor = None
+
+ self.cookie = [] #XZ: list to hold cookies (myCookie object) being changed
+ self.content_type = 'text/html'
+ self.content_disposition = ''
+ self.redirection = ''
+ self.debug = ''
+ self.attachment = ''
+
+ #XZ: Holding data (new data or existing data being changed) that should be saved to session. The data must be picklable!!!
+ self.session_data_changed = {}
+
+ self.userName = 'Guest'
+ self.privilege = 'guest'
+ if fd.input_session_data.has_key('user'):
+ self.userName = fd.input_session_data['user']
+ if fd.input_session_data.has_key('privilege'):
+ self.privilege = fd.input_session_data['privilege']
+
+ def __str__(self):
+
+ #XZ: default setting
+ thisUserName = self.userName
+ thisPrivilege = self.privilege
+ #XZ: user may just go through login or logoff page
+ if self.session_data_changed.has_key('user'):
+ thisUserName = self.session_data_changed['user']
+ if self.session_data_changed.has_key('privilege'):
+ thisPrivilege = self.session_data_changed['privilege']
+
+ if thisUserName == 'Guest':
+ userInfo = 'Welcome! <a href=/account.html><U>Login</U></a>'
+ else:
+ userInfo = 'Hi, %s! <a href=/webqtl/main.py?FormID=userLogoff><U>Logout</U></a>' % thisUserName
+
+ reload(header)
+ self.dict['header'] = header.header_string % userInfo
+
+ serverInfo = "It took %2.3f second(s) for %s to generate this page" % (time.time()-self.starttime, socket.getfqdn())
+ reload(footer)
+ self.dict['footer'] = footer.footer_string % serverInfo
+
+ slist = []
+ for item in self.contents:
+ slist.append(self.dict[item])
+ return self.template % tuple(slist)
+
+
+ def __del__(self):
+ if self.cursor:
+ self.cursor.close()
+
+ def write(self):
+ 'return string representation of this object'
+
+ if self.cursor:
+ self.cursor.close()
+
+ return str(self)
+
+ def writeFile(self, filename):
+ 'save string representation of this object into a file'
+ if self.cursor:
+ self.cursor.close()
+
+ try:
+ 'it could take a long time to generate the file, save to .tmp first'
+ fp = open(os.path.join(webqtlConfig.TMPDIR, filename+'.tmp'), 'wb')
+ fp.write(str(self))
+ fp.close()
+ path_tmp = os.path.join(webqtlConfig.TMPDIR, filename+'.tmp')
+ path_html = os.path.join(webqtlConfig.TMPDIR, filename)
+ shutil.move(path_tmp,path_html)
+ except:
+ pass
+
+ def openMysql(self):
+ try:
+ self.con = MySQLdb.Connect(db=webqtlConfig.DB_NAME,host=webqtlConfig.MYSQL_SERVER, \
+ user=webqtlConfig.DB_USER,passwd=webqtlConfig.DB_PASSWD)
+ self.cursor = self.con.cursor()
+ return 1
+ except:
+ heading = "Connect MySQL Server"
+ detail = ["Can't connect to MySQL server on '"+ webqtlConfig.MYSQL_SERVER+"':100061. \
+ The server may be down at this time"]
+ self.error(heading=heading,detail=detail,error="Error 2003")
+ return 0
+
+ def updMysql(self):
+ try:
+ self.con = MySQLdb.Connect(db=webqtlConfig.DB_UPDNAME,host=webqtlConfig.MYSQL_UPDSERVER, \
+ user=webqtlConfig.DB_UPDUSER,passwd=webqtlConfig.DB_UPDPASSWD)
+ self.cursor = self.con.cursor()
+ return 1
+ except:
+ heading = "Connect MySQL Server"
+ detail = ["update: Can't connect to MySQL server on '"+ webqtlConfig.MYSQL_UPDSERVER+"':100061. \
+ The server may be down at this time "]
+ self.error(heading=heading,detail=detail,error="Error 2003")
+ return 0
+
+ def error(self,heading="",intro=[],detail=[],title="Error",error="Error"):
+ 'generating a WebQTL style error page'
+ Heading = HT.Paragraph(heading)
+ Heading.__setattr__("class","title")
+
+ Intro = HT.Blockquote()
+ if intro:
+ for item in intro:
+ Intro.append(item)
+ else:
+ Intro.append(HT.Strong('Sorry!'),' Error occurred while processing\
+ your request.', HT.P(),'The nature of the error generated is as\
+ follows:')
+
+ Detail = HT.Blockquote()
+ Detail.append(HT.Span("%s : " % error,Class="fwb cr"))
+ if detail:
+ Detail2 = HT.Blockquote()
+ for item in detail:
+ Detail2.append(item)
+ Detail.append(HT.Italic(Detail2))
+
+ #Detail.__setattr__("class","subtitle")
+ TD_LR = HT.TD(height=200,width="100%",bgColor='#eeeeee',valign="top")
+ TD_LR.append(Heading,Intro,Detail)
+ self.dict['body'] = str(TD_LR)
+ self.dict['title'] = title
+
+ def session(self,mytitle="",myHeading=""):
+ 'generate a auto-refreshing temporary html file(waiting page)'
+ self.filename = webqtlUtil.generate_session()
+ self.dict['title'] = mytitle
+ self.dict['basehref'] = webqtlConfig.REFRESHSTR % (webqtlConfig.CGIDIR, self.filename) + "" #webqtlConfig.BASEHREF
+
+ TD_LR = HT.TD(align="center", valign="middle", height=200,width="100%", bgColor='#eeeeee')
+ Heading = HT.Paragraph(myHeading, Class="fwb fs16 cr")
+ # NL, 07/27/2010. variable 'PROGRESSBAR' has been moved from templatePage.py to webqtlUtil.py;
+ TD_LR.append(Heading, HT.BR(), webqtlUtil.PROGRESSBAR)
+ self.dict['body'] = TD_LR
+ self.writeFile(self.filename + '.html')
+ return self.filename
+
+
diff --git a/wqflask/base/webqtlCaseData.py b/wqflask/base/webqtlCaseData.py
new file mode 100755
index 00000000..4df32ca4
--- /dev/null
+++ b/wqflask/base/webqtlCaseData.py
@@ -0,0 +1,54 @@
+# Copyright (C) University of Tennessee Health Science Center, Memphis, TN.
+#
+# This program is free software: you can redistribute it and/or modify it
+# under the terms of the GNU Affero General Public License
+# as published by the Free Software Foundation, either version 3 of the
+# License, or (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
+# See the GNU Affero General Public License for more details.
+#
+# This program is available from Source Forge: at GeneNetwork Project
+# (sourceforge.net/projects/genenetwork/).
+#
+# Contact Drs. Robert W. Williams and Xiaodong Zhou (2010)
+# at rwilliams@uthsc.edu and xzhou15@uthsc.edu
+#
+#
+#
+# This module is used by GeneNetwork project (www.genenetwork.org)
+#
+# Created by GeneNetwork Core Team 2010/08/10
+#
+# Last updated by GeneNetwork Core Team 2010/10/20
+
+class webqtlCaseData:
+ """
+ one case data in one trait
+ """
+
+ val = None #Trait Value
+ var = None #Trait Variance
+ N = None #Number of individuals
+
+ def __init__(self, val=val, var=var, N=N):
+ self.val = val
+ self.var = var
+ self.N = N
+
+ def __str__(self):
+ str = ""
+ if self.val != None:
+ str += "value=%2.3f" % self.val
+ if self.var != None:
+ str += " variance=%2.3f" % self.var
+ if self.N != None:
+ str += " ndata=%d" % self.N
+ return str
+
+ __repr__ = __str__
+
+
+
diff --git a/wqflask/base/webqtlConfig.py b/wqflask/base/webqtlConfig.py
new file mode 100755
index 00000000..755595e0
--- /dev/null
+++ b/wqflask/base/webqtlConfig.py
@@ -0,0 +1,73 @@
+from webqtlConfigLocal import *
+#########################################'
+# Environment Variables - public
+#########################################
+
+#Debug Level
+#1 for debug, mod python will reload import each time
+DEBUG = 1
+
+#USER privilege
+USERDICT = {'guest':1,'user':2, 'admin':3, 'root':4}
+
+#minimum number of informative strains
+KMININFORMATIVE = 5
+
+#maximum number of traits for interval mapping
+MULTIPLEMAPPINGLIMIT = 11
+
+#maximum number of traits for correlation
+MAXCORR = 100
+
+#Daily download limit from one IP
+DAILYMAXIMUM = 1000
+
+#maximum LRS value
+MAXLRS = 460.0
+
+#temporary data life span
+MAXLIFE = 86400
+
+#MINIMUM Database public value
+PUBLICTHRESH = 0
+
+#NBCI address
+NCBI_LOCUSID = "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=%s"
+UCSC_REFSEQ = "http://genome.cse.ucsc.edu/cgi-bin/hgGene?db=%s&hgg_gene=%s&hgg_chrom=chr%s&hgg_start=%s&hgg_end=%s"
+GENBANK_ID = "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Nucleotide&cmd=search&doptcmdl=DocSum&term=%s"
+OMIM_ID = "http://www.ncbi.nlm.nih.gov/omim/%s"
+UNIGEN_ID = "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=%s&CID=%s"
+HOMOLOGENE_ID = "http://www.ncbi.nlm.nih.gov/sites/entrez?Db=homologene&Cmd=DetailsSearch&Term=%s"
+PUBMEDLINK_URL = "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=%s&dopt=Abstract"
+UCSC_POS = "http://genome.ucsc.edu/cgi-bin/hgTracks?clade=mammal&org=%s&db=%s&position=chr%s:%s-%s&pix=800&Submit=submit"
+UCSC_BLAT = 'http://genome.ucsc.edu/cgi-bin/hgBlat?org=%s&db=%s&type=0&sort=0&output=0&userSeq=%s'
+UTHSC_BLAT = 'http://ucscbrowser.genenetwork.org/cgi-bin/hgBlat?org=%s&db=%s&type=0&sort=0&output=0&userSeq=%s'
+UCSC_GENOME = "http://genome.ucsc.edu/cgi-bin/hgTracks?db=%s&position=chr%s:%d-%d&hgt.customText=http://web2qtl.utmem.edu:88/snp/chr%s"
+ENSEMBLE_BLAT = 'http://www.ensembl.org/Mus_musculus/featureview?type=AffyProbe&id=%s'
+DBSNP = 'http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=%s'
+UCSC_RUDI_TRACK_URL = " http://genome.cse.ucsc.edu/cgi-bin/hgTracks?org=%s&db=%s&hgt.customText=http://gbic.biol.rug.nl/~ralberts/tracks/%s/%s"
+GENOMEBROWSER_URL="http://ucscbrowser.genenetwork.org/cgi-bin/hgTracks?clade=mammal&org=Mouse&db=mm9&position=%s&hgt.suggest=&pix=800&Submit=submit"
+ENSEMBLETRANSCRIPT_URL="http://useast.ensembl.org/Mus_musculus/Lucene/Details?species=Mus_musculus;idx=Transcript;end=1;q=%s"
+
+SECUREDIR = GNROOT + 'secure/'
+COMMON_LIB = GNROOT + 'support/admin'
+HTMLPATH = GNROOT + 'web/'
+IMGDIR = HTMLPATH +'image/'
+IMAGESPATH = HTMLPATH + 'images/'
+UPLOADPATH = IMAGESPATH + 'upload/'
+TMPDIR = '/tmp/'
+GENODIR = HTMLPATH + 'genotypes/'
+GENO_ARCHIVE_DIR = GENODIR + 'archive/'
+TEXTDIR = HTMLPATH + 'ProbeSetFreeze_DataMatrix/'
+CMDLINEDIR = HTMLPATH + 'webqtl/cmdLine/'
+ChangableHtmlPath = GNROOT + 'web/'
+
+SITENAME = 'GN'
+PORTADDR = "http://132.192.47.32"
+BASEHREF = '<base href="http://132.192.47.32/">'
+INFOPAGEHREF = '/dbdoc/%s.html'
+GLOSSARYFILE = "/glossary.html"
+CGIDIR = '/webqtl/' #XZ: The variable name 'CGIDIR' should be changed to 'PYTHONDIR'
+SCRIPTFILE = 'main.py'
+REFRESHSTR = '<meta http-equiv="refresh" content="5;url=%s' + SCRIPTFILE +'?sid=%s">'
+REFRESHDIR = '%s' + SCRIPTFILE +'?sid=%s'
diff --git a/wqflask/base/webqtlConfigLocal.py b/wqflask/base/webqtlConfigLocal.py
new file mode 100755
index 00000000..35da73c2
--- /dev/null
+++ b/wqflask/base/webqtlConfigLocal.py
@@ -0,0 +1,19 @@
+#########################################'
+# Environment Variables - private
+#########################################
+
+MYSQL_SERVER = 'localhost'
+DB_NAME = 'db_webqtl'
+DB_USER = 'webqtlupd'
+DB_PASSWD = 'zhou&yan@ut'
+
+MYSQL_UPDSERVER = 'localhost'
+DB_UPDNAME = 'db_webqtl'
+DB_UPDUSER = 'webqtlupd'
+DB_UPDPASSWD = 'zhou&yan@ut'
+
+GNROOT = '/gnshare/gn/'
+PythonPath = '/usr/bin/python'
+PIDDLE_FONT_PATH = '/usr/lib/python2.4/site-packages/piddle/truetypefonts/'
+
+TEXTUI=1 # XZ: This is to protect GN production server. If set to 0, no text UI is allowed.
diff --git a/wqflask/base/webqtlDataset.py b/wqflask/base/webqtlDataset.py
new file mode 100755
index 00000000..da1b8601
--- /dev/null
+++ b/wqflask/base/webqtlDataset.py
@@ -0,0 +1,160 @@
+# Copyright (C) University of Tennessee Health Science Center, Memphis, TN.
+#
+# This program is free software: you can redistribute it and/or modify it
+# under the terms of the GNU Affero General Public License
+# as published by the Free Software Foundation, either version 3 of the
+# License, or (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
+# See the GNU Affero General Public License for more details.
+#
+# This program is available from Source Forge: at GeneNetwork Project
+# (sourceforge.net/projects/genenetwork/).
+#
+# Contact Drs. Robert W. Williams and Xiaodong Zhou (2010)
+# at rwilliams@uthsc.edu and xzhou15@uthsc.edu
+#
+#
+#
+# This module is used by GeneNetwork project (www.genenetwork.org)
+#
+# Created by GeneNetwork Core Team 2010/08/10
+#
+# Last updated by GeneNetwork Core Team 2010/10/20
+
+from htmlgen import HTMLgen2 as HT
+
+import webqtlConfig
+
+
+
+class webqtlDataset:
+ """
+ Database class defines a database in webqtl, can be either Microarray,
+ Published phenotype, genotype, or user input database(temp)
+ """
+
+ def __init__(self, dbName, cursor=None):
+
+ assert dbName
+ self.id = 0
+ self.name = ''
+ self.type = ''
+ self.riset = ''
+ self.cursor = cursor
+
+ #temporary storage
+ if dbName.find('Temp') >= 0:
+ self.searchfield = ['name','description']
+ self.disfield = ['name','description']
+ self.type = 'Temp'
+ self.id = 1
+ self.fullname = 'Temporary Storage'
+ self.shortname = 'Temp'
+ elif dbName.find('Publish') >= 0:
+ self.searchfield = ['name','post_publication_description','abstract','title','authors']
+ self.disfield = ['name','pubmed_id',
+ 'pre_publication_description', 'post_publication_description', 'original_description',
+ 'pre_publication_abbreviation', 'post_publication_abbreviation',
+ 'lab_code', 'submitter', 'owner', 'authorized_users',
+ 'authors','title','abstract', 'journal','volume','pages','month',
+ 'year','sequence', 'units', 'comments']
+ self.type = 'Publish'
+ elif dbName.find('Geno') >= 0:
+ self.searchfield = ['name','chr']
+ self.disfield = ['name','chr','mb', 'source2', 'sequence']
+ self.type = 'Geno'
+ else: #ProbeSet
+ self.searchfield = ['name','description','probe_target_description',
+ 'symbol','alias','genbankid','unigeneid','omim',
+ 'refseq_transcriptid','probe_set_specificity', 'probe_set_blat_score']
+ self.disfield = ['name','symbol','description','probe_target_description',
+ 'chr','mb','alias','geneid','genbankid', 'unigeneid', 'omim',
+ 'refseq_transcriptid','blatseq','targetseq','chipid', 'comments',
+ 'strand_probe','strand_gene','probe_set_target_region',
+ 'probe_set_specificity', 'probe_set_blat_score','probe_set_blat_mb_start',
+ 'probe_set_blat_mb_end', 'probe_set_strand',
+ 'probe_set_note_by_rw', 'flag']
+ self.type = 'ProbeSet'
+ self.name = dbName
+ if self.cursor and self.id == 0:
+ self.retrieveName()
+
+ def __str__(self):
+ return self.name
+
+ __repr__ = __str__
+
+
+ def getRISet(self):
+ assert self.cursor
+ if self.type == 'Publish':
+ query = '''
+ SELECT
+ InbredSet.Name, InbredSet.Id
+ FROM
+ InbredSet, PublishFreeze
+ WHERE
+ PublishFreeze.InbredSetId = InbredSet.Id AND
+ PublishFreeze.Name = "%s"
+ ''' % self.name
+ elif self.type == 'Geno':
+ query = '''
+ SELECT
+ InbredSet.Name, InbredSet.Id
+ FROM
+ InbredSet, GenoFreeze
+ WHERE
+ GenoFreeze.InbredSetId = InbredSet.Id AND
+ GenoFreeze.Name = "%s"
+ ''' % self.name
+ elif self.type == 'ProbeSet':
+ query = '''
+ SELECT
+ InbredSet.Name, InbredSet.Id
+ FROM
+ InbredSet, ProbeSetFreeze, ProbeFreeze
+ WHERE
+ ProbeFreeze.InbredSetId = InbredSet.Id AND
+ ProbeFreeze.Id = ProbeSetFreeze.ProbeFreezeId AND
+ ProbeSetFreeze.Name = "%s"
+ ''' % self.name
+ else:
+ return ""
+ self.cursor.execute(query)
+ RISet, RIID = self.cursor.fetchone()
+ if RISet == 'BXD300':
+ RISet = "BXD"
+ self.riset = RISet
+ self.risetid = RIID
+ return RISet
+
+
+ def retrieveName(self):
+ assert self.id == 0 and self.cursor
+ query = '''
+ SELECT
+ Id, Name, FullName, ShortName
+ FROM
+ %sFreeze
+ WHERE
+ public > %d AND
+ (Name = "%s" OR FullName = "%s" OR ShortName = "%s")
+ '''% (self.type, webqtlConfig.PUBLICTHRESH, self.name, self.name, self.name)
+ try:
+ self.cursor.execute(query)
+ self.id,self.name,self.fullname,self.shortname=self.cursor.fetchone()
+ except:
+ raise KeyError, `self.name`+' doesn\'t exist.'
+
+
+ def genHTML(self, Class='c0dd'):
+ return HT.Href(text = HT.Span('%s Database' % self.fullname, Class= "fwb " + Class),
+ url= webqtlConfig.INFOPAGEHREF % self.name,target="_blank")
+
+
+
+
+
diff --git a/wqflask/base/webqtlFormData.py b/wqflask/base/webqtlFormData.py
new file mode 100755
index 00000000..84e41cae
--- /dev/null
+++ b/wqflask/base/webqtlFormData.py
@@ -0,0 +1,289 @@
+# Copyright (C) University of Tennessee Health Science Center, Memphis, TN.
+#
+# This program is free software: you can redistribute it and/or modify it
+# under the terms of the GNU Affero General Public License
+# as published by the Free Software Foundation, either version 3 of the
+# License, or (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
+# See the GNU Affero General Public License for more details.
+#
+# This program is available from Source Forge: at GeneNetwork Project
+# (sourceforge.net/projects/genenetwork/).
+#
+# Contact Drs. Robert W. Williams and Xiaodong Zhou (2010)
+# at rwilliams@uthsc.edu and xzhou15@uthsc.edu
+#
+#
+#
+# This module is used by GeneNetwork project (www.genenetwork.org)
+#
+# Created by GeneNetwork Core Team 2010/08/10
+#
+# Last updated by GeneNetwork Core Team 2010/10/20
+
+from mod_python import Cookie
+import string
+import os
+
+import reaper
+
+import webqtlConfig
+import cookieData
+import sessionData
+from cgiData import cgiData
+from webqtlCaseData import webqtlCaseData
+from utility import webqtlUtil
+
+
+
+class webqtlFormData:
+ 'Represents data from a WebQTL form page, needed to generate the next page'
+ attrs = ('formID','RISet','genotype','strainlist','allstrainlist',
+ 'suggestive','significance','submitID','identification', 'enablevariance',
+ 'nperm','nboot','email','incparentsf1','genotype_1','genotype_2','traitInfo')
+
+ #XZ: Attention! All attribute values must be picklable!
+
+ def __init__(self, req = None, mod_python_session=None, FieldStorage_formdata=None):
+
+ for item in self.attrs:
+ setattr(self,item, None)
+
+ try:
+ self.remote_ip = req.connection.remote_ip
+ except:
+ self.remote_ip = '1.2.3.4'
+
+ if req and req.headers_in.has_key('referer'):
+ self.refURL = req.headers_in['referer']
+ else:
+ self.refURL = None
+
+
+ self.cookies = cookieData.cookieData(Cookie.get_cookies(req)) #XZ: dictionary type. To hold values transfered from mod_python Cookie.
+
+ #XZ: dictionary type. To hold values transfered from mod_python Session object. We assume that it is always picklable.
+ self.input_session_data = sessionData.sessionData( mod_python_session )
+
+ #XZ: FieldStorage_formdata may contain item that can't be pickled. Must convert to picklable data.
+ self.formdata = cgiData( FieldStorage_formdata )
+
+ #get Form ID
+ self.formID = self.formdata.getfirst('FormID')
+
+ #get rest of the attributes
+ if self.formID:
+ for item in self.attrs:
+ value = self.formdata.getfirst(item)
+ if value != None:
+ setattr(self,item,string.strip(value))
+
+ self.ppolar = ""
+ self.mpolar = ""
+ if self.RISet:
+ try:
+ # NL, 07/27/2010. ParInfo has been moved from webqtlForm.py to webqtlUtil.py;
+ f1, f12, self.mpolar, self.ppolar = webqtlUtil.ParInfo[self.RISet]
+ except:
+ f1 = f12 = self.mpolar = self.ppolar = None
+
+ try:
+ self.nperm = int(self.nperm)
+ self.nboot = int(self.nboot)
+ except:
+ self.nperm = 2000 #XZ: Rob asked to change the default value to 2000
+ self.nboot = 2000 #XZ: Rob asked to change the default value to 2000
+
+ if self.allstrainlist:
+ self.allstrainlist = map(string.strip, string.split(self.allstrainlist))
+ #self.readGenotype()
+ #self.readData()
+
+ if self.RISet == 'BXD300':
+ self.RISet = 'BXD'
+ else:
+ pass
+
+ def __str__(self):
+ rstr = ''
+ for item in self.attrs:
+ if item != 'genotype':
+ rstr += '%s:%s\n' % (item,str(getattr(self,item)))
+ return rstr
+
+
+ def readGenotype(self):
+ 'read genotype from .geno file'
+ if self.RISet == 'BXD300':
+ self.RISet = 'BXD'
+ else:
+ pass
+ assert self.RISet
+ #genotype_1 is Dataset Object without parents and f1
+ #genotype_2 is Dataset Object with parents and f1 (not for intercross)
+ self.genotype_1 = reaper.Dataset()
+ self.genotype_1.read(os.path.join(webqtlConfig.GENODIR, self.RISet + '.geno'))
+ try:
+ # NL, 07/27/2010. ParInfo has been moved from webqtlForm.py to webqtlUtil.py;
+ _f1, _f12, _mat, _pat = webqtlUtil.ParInfo[self.RISet]
+ except:
+ _f1 = _f12 = _mat = _pat = None
+
+ self.genotype_2 =self.genotype_1
+ if self.genotype_1.type == "riset" and _mat and _pat:
+ self.genotype_2 = self.genotype_1.add(Mat=_mat, Pat=_pat) #, F1=_f1)
+
+ #determine default genotype object
+ if self.incparentsf1 and self.genotype_1.type != "intercross":
+ self.genotype = self.genotype_2
+ else:
+ self.incparentsf1 = 0
+ self.genotype = self.genotype_1
+ self.strainlist = list(self.genotype.prgy)
+ self.f1list = self.parlist = []
+ if _f1 and _f12:
+ self.f1list = [_f1, _f12]
+ if _mat and _pat:
+ self.parlist = [_mat, _pat]
+
+ def readData(self, strainlst=[], incf1=[]):
+ 'read user input data or from trait data and analysis form'
+
+ if not self.genotype:
+ self.readGenotype()
+ if not strainlst:
+ if incf1:
+ strainlst = self.f1list + self.strainlist
+ else:
+ strainlst = self.strainlist
+
+
+ traitfiledata = self.formdata.getfirst('traitfile')
+ traitpastedata = self.formdata.getfirst('traitpaste')
+ variancefiledata = self.formdata.getfirst('variancefile')
+ variancepastedata = self.formdata.getfirst('variancepaste')
+ Nfiledata = self.formdata.getfirst('Nfile')
+
+
+ if traitfiledata:
+ tt = string.split(traitfiledata)
+ vals = map(webqtlUtil.StringAsFloat, tt)
+ elif traitpastedata:
+ tt = string.split(traitpastedata)
+ vals = map(webqtlUtil.StringAsFloat, tt)
+ else:
+ vals = map(self.FormDataAsFloat, strainlst)
+
+ if len(vals) < len(strainlst):
+ vals += [None]*(len(strainlst) - len(vals))
+ elif len(vals) > len(strainlst):
+ vals = vals[:len(strainlst)]
+ else:
+ pass
+
+
+ if variancefiledata:
+ tt = string.split(variancefiledata)
+ vars = map(webqtlUtil.StringAsFloat, tt)
+ elif variancepastedata:
+ tt = string.split(variancepastedata)
+ vars = map(webqtlUtil.StringAsFloat, tt)
+ else:
+ vars = map(self.FormVarianceAsFloat, strainlst)
+
+ if len(vars) < len(strainlst):
+ vars += [None]*(len(strainlst) - len(vars))
+ elif len(vars) > len(strainlst):
+ vars = vars[:len(strainlst)]
+ else:
+ pass
+
+ if Nfiledata:
+ tt = string.split(Nfiledata)
+ nstrains = map(webqtlUtil.IntAsFloat, tt)
+ if len(nstrains) < len(strainlst):
+ nstrains += [None]*(len(strainlst) - len(nstrains))
+ else:
+ nstrains = map(self.FormNAsFloat, strainlst)
+
+ ##vals, vars, nstrains is obsolete
+ self.allTraitData = {}
+ for i, _strain in enumerate(strainlst):
+ if vals[i] != None:
+ self.allTraitData[_strain] = webqtlCaseData(vals[i], vars[i], nstrains[i])
+
+
+
+ def informativeStrains(self, strainlst=[], incVars = 0):
+ '''if readData was called, use this to output the informative strains
+ (strain with values)'''
+ if not strainlst:
+ strainlst = self.strainlist
+ strains = []
+ vals = []
+ vars = []
+ for _strain in strainlst:
+ if self.allTraitData.has_key(_strain):
+ _val, _var = self.allTraitData[_strain].val, self.allTraitData[_strain].var
+ if _val != None:
+ if incVars:
+ if _var != None:
+ strains.append(_strain)
+ vals.append(_val)
+ vars.append(_var)
+ else:
+ strains.append(_strain)
+ vals.append(_val)
+ vars.append(None)
+ return strains, vals, vars, len(strains)
+
+
+
+ def FormDataAsFloat(self, key):
+ try:
+ return float(self.formdata.getfirst(key))
+ except:
+ return None
+
+
+ def FormVarianceAsFloat(self, key):
+ try:
+ return float(self.formdata.getfirst('V' + key))
+ except:
+ return None
+
+ def FormNAsFloat(self, key):
+ try:
+ return int(self.formdata.getfirst('N' + key))
+ except:
+ return None
+
+ def Sample(self):
+ 'Create some dummy data for testing'
+ self.RISet = 'BXD'
+ self.incparentsf1 = 'on'
+ #self.display = 9.2
+ #self.significance = 16.1
+ self.readGenotype()
+ self.identification = 'BXD : Coat color example by Lu Lu, et al'
+ #self.readGenotype()
+ #self.genotype.ReadMM('AXBXAforQTL')
+ #self.strainlist = map((lambda x, y='': '%s%s' % (y,x)), self.genotype.prgy)
+ #self.strainlist.sort()
+ self.allTraitData = {'BXD29': webqtlCaseData(3), 'BXD28': webqtlCaseData(2),
+ 'BXD25': webqtlCaseData(2), 'BXD24': webqtlCaseData(2), 'BXD27': webqtlCaseData(2),
+ 'BXD21': webqtlCaseData(1), 'BXD20': webqtlCaseData(4), 'BXD23': webqtlCaseData(4),
+ 'BXD22': webqtlCaseData(3), 'BXD14': webqtlCaseData(4), 'BXD15': webqtlCaseData(2),
+ 'BXD16': webqtlCaseData(3), 'BXD11': webqtlCaseData(4), 'BXD12': webqtlCaseData(3),
+ 'BXD13': webqtlCaseData(2), 'BXD18': webqtlCaseData(3), 'BXD19': webqtlCaseData(3),
+ 'BXD38': webqtlCaseData(3), 'BXD39': webqtlCaseData(3), 'BXD36': webqtlCaseData(2),
+ 'BXD34': webqtlCaseData(4), 'BXD35': webqtlCaseData(4), 'BXD32': webqtlCaseData(4),
+ 'BXD33': webqtlCaseData(3), 'BXD30': webqtlCaseData(1), 'BXD31': webqtlCaseData(4),
+ 'DBA/2J': webqtlCaseData(1), 'BXD8': webqtlCaseData(3), 'BXD9': webqtlCaseData(1),
+ 'BXD6': webqtlCaseData(3), 'BXD5': webqtlCaseData(3), 'BXD2': webqtlCaseData(4),
+ 'BXD1': webqtlCaseData(1), 'C57BL/6J': webqtlCaseData(4), 'B6D2F1': webqtlCaseData(4),
+ 'BXD42': webqtlCaseData(4), 'BXD40': webqtlCaseData(3)}
+
diff --git a/wqflask/base/webqtlTrait.py b/wqflask/base/webqtlTrait.py
new file mode 100755
index 00000000..f5051e45
--- /dev/null
+++ b/wqflask/base/webqtlTrait.py
@@ -0,0 +1,581 @@
+import string
+
+from htmlgen import HTMLgen2 as HT
+
+import webqtlConfig
+from webqtlCaseData import webqtlCaseData
+from webqtlDataset import webqtlDataset
+from dbFunction import webqtlDatabaseFunction
+from utility import webqtlUtil
+
+
+class webqtlTrait:
+ """
+ Trait class defines a trait in webqtl, can be either Microarray,
+ Published phenotype, genotype, or user input trait
+ """
+
+ def __init__(self, cursor = None, **kw):
+ self.cursor = cursor
+ self.db = None # database object
+ self.name = '' # Trait ID, ProbeSet ID, Published ID, etc.
+ self.cellid = ''
+ self.identification = 'un-named trait'
+ self.riset = ''
+ self.haveinfo = 0
+ self.sequence = '' # Blat sequence, available for ProbeSet
+ self.data = {}
+ for name, value in kw.items():
+ if self.__dict__.has_key(name):
+ setattr(self, name, value)
+ elif name == 'fullname':
+ name2 = value.split("::")
+ if len(name2) == 2:
+ self.db, self.name = name2
+ elif len(name2) == 3:
+ self.db, self.name, self.cellid = name2
+ else:
+ raise KeyError, `value` + ' parameter format error.'
+ else:
+ raise KeyError, `name`+' not a valid parameter for this class.'
+
+ if self.db and type(self.db) == type("1"):
+ assert self.cursor
+ self.db = webqtlDataset(self.db, self.cursor)
+
+ #if self.db == None, not from a database
+ if self.db:
+ if self.db.type == "Temp":
+ self.cursor.execute('''
+ SELECT
+ InbredSet.Name
+ FROM
+ InbredSet, Temp
+ WHERE
+ Temp.InbredSetId = InbredSet.Id AND
+ Temp.Name = "%s"
+ ''' % self.name)
+ self.riset = self.cursor.fetchone()[0]
+ else:
+ self.riset = self.db.getRISet()
+
+ #
+ # In ProbeSet, there are maybe several annotations match one sequence
+ # so we need use sequence(BlatSeq) as the identification, when we update
+ # one annotation, we update the others who match the sequence also.
+ #
+ # Hongqiang Li, 3/3/2008
+ #
+
+ #XZ, 05/08/2009: This block is not neccessary. We can add 'BlatSeq' into disfield.
+ # The variable self.sequence should be changed to self.BlatSeq
+ # It also should be changed in other places where it are used.
+
+ if self.db:
+ if self.db.type == 'ProbeSet':
+ query = '''
+ SELECT
+ ProbeSet.BlatSeq
+ FROM
+ ProbeSet, ProbeSetFreeze, ProbeSetXRef
+ WHERE
+ ProbeSet.Id=ProbeSetXRef.ProbeSetId and
+ ProbeSetFreeze.Id = ProbeSetXRef.ProbeSetFreezeId and
+ ProbeSet.Name = "%s" and
+ ProbeSetFreeze.Name = "%s"
+ ''' % (self.name, self.db.name)
+ self.cursor.execute(query)
+ self.sequence = self.cursor.fetchone()[0]
+
+
+ def getName(self):
+ str = ""
+ if self.db and self.name:
+ str = "%s::%s" % (self.db, self.name)
+ if self.cellid:
+ str += "::" + self.cellid
+ else:
+ str = self.description
+ return str
+
+ #
+ # when user enter a trait or GN generate a trait, user want show the name
+ # not the name that generated by GN randomly, the two follow function are
+ # used to give the real name and the database. displayName() will show the
+ # database also, getGivenName() just show the name.
+ # For other trait, displayName() as same as getName(), getGivenName() as
+ # same as self.name
+ #
+ # Hongqiang 11/29/07
+ #
+ def getGivenName(self):
+ str = self.name
+ if self.db and self.name:
+ if self.db.type=='Temp':
+ self.cursor.execute('SELECT description FROM Temp WHERE Name=%s',self.name)
+ desc = self.cursor.fetchone()[0]
+ if desc.__contains__('PCA'):
+ desc = desc[desc.rindex(':')+1:].strip()
+ else:
+ desc = desc[:desc.index('entered')].strip()
+ str = desc
+ return str
+
+ def displayName(self):
+ str = ""
+ if self.db and self.name:
+ if self.db.type=='Temp':
+ desc = self.description
+ if desc.__contains__('PCA'):
+ desc = desc[desc.rindex(':')+1:].strip()
+ else:
+ desc = desc[:desc.index('entered')].strip()
+ str = "%s::%s" % (self.db, desc)
+ else:
+ str = "%s::%s" % (self.db, self.name)
+ if self.cellid:
+ str += "::" + self.cellid
+ else:
+ str = self.description
+
+ return str
+
+
+ #def __str__(self):
+ # #return "%s %s" % (self.getName(), self.riset)
+ # return self.getName()
+ __str__ = getName
+ __repr__ = __str__
+
+ def exportData(self, strainlist, type="val"):
+ """
+ export data according to strainlist
+ mostly used in calculating correlation
+ """
+ result = []
+ for strain in strainlist:
+ if self.data.has_key(strain):
+ if type=='val':
+ result.append(self.data[strain].val)
+ elif type=='var':
+ result.append(self.data[strain].var)
+ elif type=='N':
+ result.append(self.data[strain].N)
+ else:
+ raise KeyError, `type`+' type is incorrect.'
+ else:
+ result.append(None)
+ return result
+
+ def exportInformative(self, incVar=0):
+ """
+ export informative strain
+ mostly used in qtl regression
+ """
+ strains = []
+ vals = []
+ vars = []
+ for strain, value in self.data.items():
+ if value.val != None:
+ if not incVar or value.var != None:
+ strains.append(strain)
+ vals.append(value.val)
+ vars.append(value.var)
+ return strains, vals, vars
+
+
+ #
+ # In ProbeSet, there are maybe several annotations match one sequence
+ # so we need use sequence(BlatSeq) as the identification, when we update
+ # one annotation, we update the others who match the sequence also.
+ #
+ # Hongqiang Li, 3/3/2008
+ #
+ def getSequence(self):
+ assert self.cursor
+ if self.db.type == 'ProbeSet':
+ query = '''
+ SELECT
+ ProbeSet.BlatSeq
+ FROM
+ ProbeSet, ProbeSetFreeze, ProbeSetXRef
+ WHERE
+ ProbeSet.Id=ProbeSetXRef.ProbeSetId and
+ ProbeSetFreeze.Id = ProbeSetXRef.ProbSetFreezeId and
+ ProbeSet.Name = %s
+ ProbeSetFreeze.Name = %s
+ ''' , (self.name, self.db.name)
+ self.cursor.execute(query)
+ results = self.fetchone()
+
+ return results[0]
+
+
+
+ def retrieveData(self, strainlist=[]):
+ assert self.db and self.cursor
+
+ if self.db.type == 'Temp':
+ query = '''
+ SELECT
+ Strain.Name, TempData.value, TempData.SE, TempData.NStrain, TempData.Id
+ FROM
+ TempData, Temp, Strain
+ WHERE
+ TempData.StrainId = Strain.Id AND
+ TempData.Id = Temp.DataId AND
+ Temp.name = '%s'
+ Order BY
+ Strain.Name
+ ''' % self.name
+ #XZ, 03/02/2009: Xiaodong changed Data to PublishData, SE to PublishSE
+ elif self.db.type == 'Publish':
+ query = '''
+ SELECT
+ Strain.Name, PublishData.value, PublishSE.error, NStrain.count, PublishData.Id
+ FROM
+ (PublishData, Strain, PublishXRef, PublishFreeze)
+ left join PublishSE on
+ (PublishSE.DataId = PublishData.Id AND PublishSE.StrainId = PublishData.StrainId)
+ left join NStrain on
+ (NStrain.DataId = PublishData.Id AND
+ NStrain.StrainId = PublishData.StrainId)
+ WHERE
+ PublishXRef.InbredSetId = PublishFreeze.InbredSetId AND
+ PublishData.Id = PublishXRef.DataId AND PublishXRef.Id = %s AND
+ PublishFreeze.Id = %d AND PublishData.StrainId = Strain.Id
+ Order BY
+ Strain.Name
+ ''' % (self.name, self.db.id)
+
+ #XZ, 03/02/2009: Xiaodong changed Data to ProbeData, SE to ProbeSE
+ elif self.cellid:
+ #Probe Data
+ query = '''
+ SELECT
+ Strain.Name, ProbeData.value, ProbeSE.error, ProbeData.Id
+ FROM
+ (ProbeData, ProbeFreeze, ProbeSetFreeze, ProbeXRef,
+ Strain, Probe, ProbeSet)
+ left join ProbeSE on
+ (ProbeSE.DataId = ProbeData.Id AND ProbeSE.StrainId = ProbeData.StrainId)
+ WHERE
+ Probe.Name = '%s' AND ProbeSet.Name = '%s' AND
+ Probe.ProbeSetId = ProbeSet.Id AND
+ ProbeXRef.ProbeId = Probe.Id AND
+ ProbeXRef.ProbeFreezeId = ProbeFreeze.Id AND
+ ProbeSetFreeze.ProbeFreezeId = ProbeFreeze.Id AND
+ ProbeSetFreeze.Name = '%s' AND
+ ProbeXRef.DataId = ProbeData.Id AND
+ ProbeData.StrainId = Strain.Id
+ Order BY
+ Strain.Name
+ ''' % (self.cellid, self.name, self.db.name)
+ #XZ, 03/02/2009: Xiaodong added this block for ProbeSetData and ProbeSetSE
+ elif self.db.type == 'ProbeSet':
+ #ProbeSet Data
+ query = '''
+ SELECT
+ Strain.Name, ProbeSetData.value, ProbeSetSE.error, ProbeSetData.Id
+ FROM
+ (ProbeSetData, ProbeSetFreeze, Strain, ProbeSet, ProbeSetXRef)
+ left join ProbeSetSE on
+ (ProbeSetSE.DataId = ProbeSetData.Id AND ProbeSetSE.StrainId = ProbeSetData.StrainId)
+ WHERE
+ ProbeSet.Name = '%s' AND ProbeSetXRef.ProbeSetId = ProbeSet.Id AND
+ ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id AND
+ ProbeSetFreeze.Name = '%s' AND
+ ProbeSetXRef.DataId = ProbeSetData.Id AND
+ ProbeSetData.StrainId = Strain.Id
+ Order BY
+ Strain.Name
+ ''' % (self.name, self.db.name)
+ #XZ, 03/02/2009: Xiaodong changeded Data to GenoData, SE to GenoSE
+ else:
+ #Geno Data
+ #XZ: The SpeciesId is not necessary, but it's nice to keep it to speed up database search.
+ query = '''
+ SELECT
+ Strain.Name, GenoData.value, GenoSE.error, GenoData.Id
+ FROM
+ (GenoData, GenoFreeze, Strain, Geno, GenoXRef)
+ left join GenoSE on
+ (GenoSE.DataId = GenoData.Id AND GenoSE.StrainId = GenoData.StrainId)
+ WHERE
+ Geno.SpeciesId = %s AND Geno.Name = '%s' AND GenoXRef.GenoId = Geno.Id AND
+ GenoXRef.GenoFreezeId = GenoFreeze.Id AND
+ GenoFreeze.Name = '%s' AND
+ GenoXRef.DataId = GenoData.Id AND
+ GenoData.StrainId = Strain.Id
+ Order BY
+ Strain.Name
+ ''' % (webqtlDatabaseFunction.retrieveSpeciesId(self.cursor, self.db.riset), self.name, self.db.name)
+
+
+ self.cursor.execute(query)
+ results = self.cursor.fetchall()
+ self.data.clear()
+ if results:
+ self.mysqlid = results[0][-1]
+ if strainlist:
+ for item in results:
+ if item[0] in strainlist:
+ val = item[1]
+ if val != None:
+ var = item[2]
+ ndata = None
+ if self.db.type in ('Publish', 'Temp'):
+ ndata = item[3]
+ self.data[item[0]] = webqtlCaseData(val, var, ndata)
+ #end for
+ else:
+ for item in results:
+ val = item[1]
+ if val != None:
+ var = item[2]
+ ndata = None
+ if self.db.type in ('Publish', 'Temp'):
+ ndata = item[3]
+ self.data[item[0]] = webqtlCaseData(val, var, ndata)
+ #end for
+ #end if
+ else:
+ pass
+
+ def keys(self):
+ return self.__dict__.keys()
+
+ def has_key(self, key):
+ return self.__dict__.has_key(key)
+
+ def items(self):
+ return self.__dict__.items()
+
+ def retrieveInfo(self, QTL = None):
+ assert self.db and self.cursor
+ if self.db.type == 'Publish':
+ #self.db.DisField = ['Name','PubMed_ID','Phenotype','Abbreviation','Authors','Title',\
+ # 'Abstract', 'Journal','Volume','Pages','Month','Year','Sequence',\
+ # 'Units', 'comments']
+ query = '''
+ SELECT
+ PublishXRef.Id, Publication.PubMed_ID,
+ Phenotype.Pre_publication_description, Phenotype.Post_publication_description, Phenotype.Original_description,
+ Phenotype.Pre_publication_abbreviation, Phenotype.Post_publication_abbreviation,
+ Phenotype.Lab_code, Phenotype.Submitter, Phenotype.Owner, Phenotype.Authorized_Users,
+ Publication.Authors, Publication.Title, Publication.Abstract,
+ Publication.Journal, Publication.Volume, Publication.Pages,
+ Publication.Month, Publication.Year, PublishXRef.Sequence,
+ Phenotype.Units, PublishXRef.comments
+ FROM
+ PublishXRef, Publication, Phenotype, PublishFreeze
+ WHERE
+ PublishXRef.Id = %s AND
+ Phenotype.Id = PublishXRef.PhenotypeId AND
+ Publication.Id = PublishXRef.PublicationId AND
+ PublishXRef.InbredSetId = PublishFreeze.InbredSetId AND
+ PublishFreeze.Id =%s
+ ''' % (self.name, self.db.id)
+ #XZ, 05/08/2009: Xiaodong add this block to use ProbeSet.Id to find the probeset instead of just using ProbeSet.Name
+ #XZ, 05/08/2009: to avoid the problem of same probeset name from different platforms.
+ elif self.db.type == 'ProbeSet':
+ disfieldString = string.join(self.db.disfield,',ProbeSet.')
+ disfieldString = 'ProbeSet.' + disfieldString
+ query = """
+ SELECT %s
+ FROM ProbeSet, ProbeSetFreeze, ProbeSetXRef
+ WHERE
+ ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id AND
+ ProbeSetXRef.ProbeSetId = ProbeSet.Id AND
+ ProbeSetFreeze.Name = '%s' AND
+ ProbeSet.Name = '%s'
+ """ % (disfieldString, self.db.name, self.name)
+ #XZ, 05/08/2009: We also should use Geno.Id to find marker instead of just using Geno.Name
+ # to avoid the problem of same marker name from different species.
+ elif self.db.type == 'Geno':
+ disfieldString = string.join(self.db.disfield,',Geno.')
+ disfieldString = 'Geno.' + disfieldString
+ query = """
+ SELECT %s
+ FROM Geno, GenoFreeze, GenoXRef
+ WHERE
+ GenoXRef.GenoFreezeId = GenoFreeze.Id AND
+ GenoXRef.GenoId = Geno.Id AND
+ GenoFreeze.Name = '%s' AND
+ Geno.Name = '%s'
+ """ % (disfieldString, self.db.name, self.name)
+ else: #Temp type
+ query = 'SELECT %s FROM %s WHERE Name = "%s"' % \
+ (string.join(self.db.disfield,','), self.db.type, self.name)
+
+
+ self.cursor.execute(query)
+ traitInfo = self.cursor.fetchone()
+ if traitInfo:
+ self.haveinfo = 1
+
+ #XZ: assign SQL query result to trait attributes.
+ for i, field in enumerate(self.db.disfield):
+ setattr(self, field, traitInfo[i])
+
+ if self.db.type == 'Publish':
+ self.confidential = 0
+ if self.pre_publication_description and not self.pubmed_id:
+ self.confidential = 1
+
+ self.homologeneid = None
+ if self.db.type == 'ProbeSet' and self.riset and self.geneid:
+ #XZ, 05/26/2010: From time to time, this query get error message because some geneid values in database are not number.
+ #XZ: So I have to test if geneid is number before execute the query.
+ #XZ: The geneid values in database should be cleaned up.
+ try:
+ junk = float(self.geneid)
+ geneidIsNumber = 1
+ except:
+ geneidIsNumber = 0
+
+ if geneidIsNumber:
+ query = """
+ SELECT
+ HomologeneId
+ FROM
+ Homologene, Species, InbredSet
+ WHERE
+ Homologene.GeneId =%s AND
+ InbredSet.Name = '%s' AND
+ InbredSet.SpeciesId = Species.Id AND
+ Species.TaxonomyId = Homologene.TaxonomyId
+ """ % (self.geneid, self.riset)
+ self.cursor.execute(query)
+ result = self.cursor.fetchone()
+ else:
+ result = None
+
+ if result:
+ self.homologeneid = result[0]
+
+ if QTL:
+ if self.db.type == 'ProbeSet' and not self.cellid:
+ query = '''
+ SELECT
+ ProbeSetXRef.Locus, ProbeSetXRef.LRS, ProbeSetXRef.pValue, ProbeSetXRef.mean
+ FROM
+ ProbeSetXRef, ProbeSet
+ WHERE
+ ProbeSetXRef.ProbeSetId = ProbeSet.Id AND
+ ProbeSet.Name = "%s" AND
+ ProbeSetXRef.ProbeSetFreezeId =%s
+ ''' % (self.name, self.db.id)
+ self.cursor.execute(query)
+ traitQTL = self.cursor.fetchone()
+ if traitQTL:
+ self.locus, self.lrs, self.pvalue, self.mean = traitQTL
+ else:
+ self.locus = self.lrs = self.pvalue = self.mean = ""
+ if self.db.type == 'Publish':
+ query = '''
+ SELECT
+ PublishXRef.Locus, PublishXRef.LRS
+ FROM
+ PublishXRef, PublishFreeze
+ WHERE
+ PublishXRef.Id = %s AND
+ PublishXRef.InbredSetId = PublishFreeze.InbredSetId AND
+ PublishFreeze.Id =%s
+ ''' % (self.name, self.db.id)
+ self.cursor.execute(query)
+ traitQTL = self.cursor.fetchone()
+ if traitQTL:
+ self.locus, self.lrs = traitQTL
+ else:
+ self.locus = self.lrs = ""
+ else:
+ raise KeyError, `self.name`+' information is not found in the database.'
+
+ def genHTML(self, formName = "", dispFromDatabase=0, privilege="guest", userName="Guest", authorized_users=""):
+ if not self.haveinfo:
+ self.retrieveInfo()
+
+ if self.db.type == 'Publish':
+ PubMedLink = ""
+ if self.pubmed_id:
+ PubMedLink = HT.Href(text="PubMed %d : " % self.pubmed_id,
+ target = "_blank", url = webqtlConfig.PUBMEDLINK_URL % self.pubmed_id)
+ else:
+ PubMedLink = HT.Span("Unpublished : ", Class="fs15")
+
+ if formName:
+ setDescription2 = HT.Href(url="javascript:showDatabase3('%s','%s','%s','')" %
+ (formName, self.db.name, self.name), Class = "fs14")
+ else:
+ setDescription2 = HT.Href(url="javascript:showDatabase2('%s','%s','')" %
+ (self.db.name,self.name), Class = "fs14")
+
+ if self.confidential and not webqtlUtil.hasAccessToConfidentialPhenotypeTrait(privilege=privilege, userName=userName, authorized_users=authorized_users):
+ setDescription2.append('RecordID/%s - %s' % (self.name, self.pre_publication_description))
+ else:
+ setDescription2.append('RecordID/%s - %s' % (self.name, self.post_publication_description))
+
+ #XZ 03/26/2011: Xiaodong comment out the following two lins as Rob asked. Need to check with Rob why in PublishXRef table, there are few row whose Sequence > 1.
+ #if self.sequence > 1:
+ # setDescription2.append(' btach %d' % self.sequence)
+ if self.authors:
+ a1 = string.split(self.authors,',')[0]
+ while a1[0] == '"' or a1[0] == "'" :
+ a1 = a1[1:]
+ setDescription2.append(' by ')
+ setDescription2.append(HT.Italic('%s, and colleagues' % a1))
+ setDescription = HT.Span(PubMedLink, setDescription2)
+
+ elif self.db.type == 'Temp':
+ setDescription = HT.Href(text="%s" % (self.description),url="javascript:showDatabase2\
+ ('%s','%s','')" % (self.db.name,self.name), Class = "fs14")
+ setDescription = HT.Span(setDescription)
+
+ elif self.db.type == 'Geno': # Genome DB only available for single search
+ if formName:
+ setDescription = HT.Href(text="Locus %s [Chr %s @ %s Mb]" % (self.name,self.chr,\
+ '%2.3f' % self.mb),url="javascript:showDatabase3('%s','%s','%s','')" % \
+ (formName, self.db.name, self.name), Class = "fs14")
+ else:
+ setDescription = HT.Href(text="Locus %s [Chr %s @ %s Mb]" % (self.name,self.chr,\
+ '%2.3f' % self.mb),url="javascript:showDatabase2('%s','%s','')" % \
+ (self.db.name,self.name), Class = "fs14")
+
+ setDescription = HT.Span(setDescription)
+
+ else:
+ if self.cellid:
+ if formName:
+ setDescription = HT.Href(text="ProbeSet/%s/%s" % (self.name, self.cellid),url=\
+ "javascript:showDatabase3('%s','%s','%s','%s')" % (formName, self.db.name,self.name,self.cellid), \
+ Class = "fs14")
+ else:
+ setDescription = HT.Href(text="ProbeSet/%s/%s" % (self.name,self.cellid),url=\
+ "javascript:showDatabase2('%s','%s','%s')" % (self.db.name,self.name,self.cellid), \
+ Class = "fs14")
+ else:
+ if formName:
+ setDescription = HT.Href(text="ProbeSet/%s" % self.name, url=\
+ "javascript:showDatabase3('%s','%s','%s','')" % (formName, self.db.name,self.name), \
+ Class = "fs14")
+ else:
+ setDescription = HT.Href(text="ProbeSet/%s" % self.name, url=\
+ "javascript:showDatabase2('%s','%s','')" % (self.db.name,self.name), \
+ Class = "fs14")
+ if self.symbol and self.chr and self.mb:
+ setDescription.append(' [')
+ setDescription.append(HT.Italic('%s' % self.symbol,Class="cdg fwb"))
+ setDescription.append(' on Chr %s @ %s Mb]' % (self.chr,self.mb))
+ if self.description:
+ setDescription.append(': %s' % self.description)
+ if self.probe_target_description:
+ setDescription.append('; %s' % self.probe_target_description)
+ setDescription = HT.Span(setDescription)
+
+ if self.db.type != 'Temp' and dispFromDatabase:
+ setDescription.append( ' --- FROM : ')
+ setDescription.append(self.db.genHTML(Class='cori'))
+ return setDescription
+
+