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authorZachary Sloan2012-12-05 18:03:23 -0600
committerZachary Sloan2012-12-05 18:03:23 -0600
commita7cc1119ebfbfab3ba5260be75c87cd4496f09b7 (patch)
tree92965e459267bf9d11aa3519e69789b0aa8bcc81 /wqflask/base/webqtlTrait.py
parent292d177f768e8f949bc50f8896b560879aaae178 (diff)
downloadgenenetwork2-a7cc1119ebfbfab3ba5260be75c87cd4496f09b7.tar.gz
Renamed webqtlTrait.py to trait.py
Renamed webqtlTrait class to GeneralTrait Began process of removing fd from show_trait.py Created DatasetGroup object in data_set.py (this may end up becoming its own file later if it becomes big enough)
Diffstat (limited to 'wqflask/base/webqtlTrait.py')
-rwxr-xr-xwqflask/base/webqtlTrait.py695
1 files changed, 0 insertions, 695 deletions
diff --git a/wqflask/base/webqtlTrait.py b/wqflask/base/webqtlTrait.py
deleted file mode 100755
index 5367b41f..00000000
--- a/wqflask/base/webqtlTrait.py
+++ /dev/null
@@ -1,695 +0,0 @@
-from __future__ import division, print_function
-
-import string
-
-from htmlgen import HTMLgen2 as HT
-
-import webqtlConfig
-from webqtlCaseData import webqtlCaseData
-from data_set import create_dataset
-from dbFunction import webqtlDatabaseFunction
-from utility import webqtlUtil
-
-from MySQLdb import escape_string as escape
-from pprint import pformat as pf
-
-from flask import Flask, g
-
-class GeneralTrait:
- """
- Trait class defines a trait in webqtl, can be either Microarray,
- Published phenotype, genotype, or user input trait
-
- """
-
- def __init__(self, **kw):
- print("in GeneralTrait")
- self.dataset = kw.get('dataset', None) # database object
- self.name = kw.get('name', None) # Trait ID, ProbeSet ID, Published ID, etc.
- self.cellid = kw.get('cellid', None)
- self.identification = kw.get('identification', 'un-named trait')
- self.group = kw.get('group', None)
- self.haveinfo = kw.get('haveinfo', False)
- self.sequence = kw.get('sequence', None) # Blat sequence, available for ProbeSet
- self.data = kw.get('data', {})
-
- if kw.get('fullname'):
- name2 = value.split("::")
- if len(name2) == 2:
- self.dataset, self.name = name2
- elif len(name2) == 3:
- self.dataset, self.name, self.cellid = name2
-
- #if self.dataset and isinstance(self.dataset, basestring):
- self.dataset = create_dataset(self.dataset.name)
-
- print("self.dataset is:", self.dataset, type(self.dataset))
- #if self.dataset:
-
- self.dataset.get_group()
-
- if self.dataset.type == "Temp":
- self.cursor.execute('''
- SELECT
- InbredSet.Name
- FROM
- InbredSet, Temp
- WHERE
- Temp.InbredSetId = InbredSet.Id AND
- Temp.Name = "%s"
- ''', self.name)
- self.group = self.cursor.fetchone()[0]
- else:
- self.group = self.dataset.get_group()
-
- print("trinity, self.group is:", self.group)
-
- #
- # In ProbeSet, there are maybe several annotations match one sequence
- # so we need use sequence(BlatSeq) as the identification, when we update
- # one annotation, we update the others who match the sequence also.
- #
- # Hongqiang Li, 3/3/2008
- #
-
- #XZ, 05/08/2009: This block is not neccessary. We can add 'BlatSeq' into disfield.
- # The variable self.sequence should be changed to self.BlatSeq
- # It also should be changed in other places where it are used.
-
- #if self.dataset:
- if self.dataset.type == 'ProbeSet':
- print("Doing ProbeSet Query")
- query = '''
- SELECT
- ProbeSet.BlatSeq
- FROM
- ProbeSet, ProbeSetFreeze, ProbeSetXRef
- WHERE
- ProbeSet.Id=ProbeSetXRef.ProbeSetId and
- ProbeSetFreeze.Id = ProbeSetXRef.ProbeSetFreezeId and
- ProbeSet.Name = %s and
- ProbeSetFreeze.Name = %s
- ''', (self.name, self.dataset.name)
- print("query is:", query)
- self.sequence = g.db.execute(*query).fetchone()[0]
- #self.sequence = self.cursor.fetchone()[0]
- print("self.sequence is:", self.sequence)
-
-
- def getName(self):
- str = ""
- if self.dataset and self.name:
- str = "%s::%s" % (self.dataset, self.name)
- if self.cellid:
- str += "::" + self.cellid
- else:
- str = self.description
- return str
-
- #
- # when user enter a trait or GN generate a trait, user want show the name
- # not the name that generated by GN randomly, the two follow function are
- # used to give the real name and the database. displayName() will show the
- # database also, getGivenName() just show the name.
- # For other trait, displayName() as same as getName(), getGivenName() as
- # same as self.name
- #
- # Hongqiang 11/29/07
- #
- def getGivenName(self):
- str = self.name
- if self.dataset and self.name:
- if self.dataset.type=='Temp':
- self.cursor.execute('SELECT description FROM Temp WHERE Name=%s', self.name)
- desc = self.cursor.fetchone()[0]
- if desc.__contains__('PCA'):
- desc = desc[desc.rindex(':')+1:].strip()
- else:
- desc = desc[:desc.index('entered')].strip()
- str = desc
- return str
-
- def displayName(self):
- str = ""
- if self.dataset and self.name:
- if self.dataset.type=='Temp':
- desc = self.description
- if desc.__contains__('PCA'):
- desc = desc[desc.rindex(':')+1:].strip()
- else:
- desc = desc[:desc.index('entered')].strip()
- str = "%s::%s" % (self.dataset, desc)
- else:
- str = "%s::%s" % (self.dataset, self.name)
- if self.cellid:
- str += "::" + self.cellid
- else:
- str = self.description
-
- return str
-
-
- #def __str__(self):
- # #return "%s %s" % (self.getName(), self.group)
- # return self.getName()
- #__str__ = getName
- #__repr__ = __str__
-
- def exportData(self, samplelist, type="val"):
- """
- export data according to samplelist
- mostly used in calculating correlation
- """
- result = []
- for sample in samplelist:
- if self.data.has_key(sample):
- if type=='val':
- result.append(self.data[sample].val)
- elif type=='var':
- result.append(self.data[sample].var)
- elif type=='N':
- result.append(self.data[sample].N)
- else:
- raise KeyError, `type`+' type is incorrect.'
- else:
- result.append(None)
- return result
-
- def exportInformative(self, incVar=0):
- """
- export informative sample
- mostly used in qtl regression
- """
- samples = []
- vals = []
- vars = []
- for sample, value in self.data.items():
- if value.val != None:
- if not incVar or value.var != None:
- samples.append(sample)
- vals.append(value.val)
- vars.append(value.var)
- return samples, vals, vars
-
-
- #
- # In ProbeSet, there are maybe several annotations match one sequence
- # so we need use sequence(BlatSeq) as the identification, when we update
- # one annotation, we update the others who match the sequence also.
- #
- # Hongqiang Li, 3/3/2008
- #
- def getSequence(self):
- assert self.cursor
- if self.dataset.type == 'ProbeSet':
- self.cursor.execute('''
- SELECT
- ProbeSet.BlatSeq
- FROM
- ProbeSet, ProbeSetFreeze, ProbeSetXRef
- WHERE
- ProbeSet.Id=ProbeSetXRef.ProbeSetId and
- ProbeSetFreeze.Id = ProbeSetXRef.ProbSetFreezeId and
- ProbeSet.Name = %s
- ProbeSetFreeze.Name = %s
- ''', self.name, self.dataset.name)
- #self.cursor.execute(query)
- results = self.fetchone()
-
- return results[0]
-
-
-
- def retrieveData(self, samplelist=None):
-
- if samplelist == None:
- samplelist = []
- assert self.dataset and self.cursor
-
- if self.dataset.type == 'Temp':
- query = '''
- SELECT
- Strain.Name, TempData.value, TempData.SE, TempData.NStrain, TempData.Id
- FROM
- TempData, Temp, Strain
- WHERE
- TempData.StrainId = Strain.Id AND
- TempData.Id = Temp.DataId AND
- Temp.name = '%s'
- Order BY
- Strain.Name
- ''' % self.name
- #XZ, 03/02/2009: Xiaodong changed Data to PublishData, SE to PublishSE
- elif self.dataset.type == 'Publish':
- query = '''
- SELECT
- Strain.Name, PublishData.value, PublishSE.error, NStrain.count, PublishData.Id
- FROM
- (PublishData, Strain, PublishXRef, PublishFreeze)
- left join PublishSE on
- (PublishSE.DataId = PublishData.Id AND PublishSE.StrainId = PublishData.StrainId)
- left join NStrain on
- (NStrain.DataId = PublishData.Id AND
- NStrain.StrainId = PublishData.StrainId)
- WHERE
- PublishXRef.InbredSetId = PublishFreeze.InbredSetId AND
- PublishData.Id = PublishXRef.DataId AND PublishXRef.Id = %s AND
- PublishFreeze.Id = %d AND PublishData.StrainId = Strain.Id
- Order BY
- Strain.Name
- ''' % (self.name, self.dataset.id)
-
- #XZ, 03/02/2009: Xiaodong changed Data to ProbeData, SE to ProbeSE
- elif self.cellid:
- #Probe Data
- query = '''
- SELECT
- Strain.Name, ProbeData.value, ProbeSE.error, ProbeData.Id
- FROM
- (ProbeData, ProbeFreeze, ProbeSetFreeze, ProbeXRef,
- Strain, Probe, ProbeSet)
- left join ProbeSE on
- (ProbeSE.DataId = ProbeData.Id AND ProbeSE.StrainId = ProbeData.StrainId)
- WHERE
- Probe.Name = '%s' AND ProbeSet.Name = '%s' AND
- Probe.ProbeSetId = ProbeSet.Id AND
- ProbeXRef.ProbeId = Probe.Id AND
- ProbeXRef.ProbeFreezeId = ProbeFreeze.Id AND
- ProbeSetFreeze.ProbeFreezeId = ProbeFreeze.Id AND
- ProbeSetFreeze.Name = '%s' AND
- ProbeXRef.DataId = ProbeData.Id AND
- ProbeData.StrainId = Strain.Id
- Order BY
- Strain.Name
- ''' % (self.cellid, self.name, self.dataset.name)
- #XZ, 03/02/2009: Xiaodong added this block for ProbeSetData and ProbeSetSE
- elif self.dataset.type == 'ProbeSet':
- #ProbeSet Data
- query = '''
- SELECT
- Strain.Name, ProbeSetData.value, ProbeSetSE.error, ProbeSetData.Id
- FROM
- (ProbeSetData, ProbeSetFreeze, Strain, ProbeSet, ProbeSetXRef)
- left join ProbeSetSE on
- (ProbeSetSE.DataId = ProbeSetData.Id AND ProbeSetSE.StrainId = ProbeSetData.StrainId)
- WHERE
- ProbeSet.Name = '%s' AND ProbeSetXRef.ProbeSetId = ProbeSet.Id AND
- ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id AND
- ProbeSetFreeze.Name = '%s' AND
- ProbeSetXRef.DataId = ProbeSetData.Id AND
- ProbeSetData.StrainId = Strain.Id
- Order BY
- Strain.Name
- ''' % (self.name, self.dataset.name)
- #XZ, 03/02/2009: Xiaodong changeded Data to GenoData, SE to GenoSE
- else:
- #Geno Data
- #XZ: The SpeciesId is not necessary, but it's nice to keep it to speed up database search.
- query = '''
- SELECT
- Strain.Name, GenoData.value, GenoSE.error, GenoData.Id
- FROM
- (GenoData, GenoFreeze, Strain, Geno, GenoXRef)
- left join GenoSE on
- (GenoSE.DataId = GenoData.Id AND GenoSE.StrainId = GenoData.StrainId)
- WHERE
- Geno.SpeciesId = %s AND Geno.Name = '%s' AND GenoXRef.GenoId = Geno.Id AND
- GenoXRef.GenoFreezeId = GenoFreeze.Id AND
- GenoFreeze.Name = '%s' AND
- GenoXRef.DataId = GenoData.Id AND
- GenoData.StrainId = Strain.Id
- Order BY
- Strain.Name
- ''' % (webqtlDatabaseFunction.retrieveSpeciesId(self.cursor, self.dataset.group), self.name, self.dataset.name)
-
-
- self.cursor.execute(query)
- results = self.cursor.fetchall()
- self.data.clear()
-
- if results:
- self.mysqlid = results[0][-1]
- #if samplelist:
- for item in results:
- #name, value, variance, num_cases = item
- if not samplelist or (samplelist and name in samplelist):
- #if value != None:
- # num_cases = None
- # if self.dataset.type in ('Publish', 'Temp'):
- # ndata = item[3]
- name = item[0]
- self.data[name] = webqtlCaseData(*item) #name, value, variance, num_cases)
- #end for
- # else:
- # for item in results:
- # val = item[1]
- # if val != None:
- # var = item[2]
- # ndata = None
- # if self.dataset.type in ('Publish', 'Temp'):
- # ndata = item[3]
- # self.data[item[0]] = webqtlCaseData(val, var, ndata)
- # #end for
- # #end if
- #else:
- # pass
-
- #def keys(self):
- # return self.__dict__.keys()
- #
- #def has_key(self, key):
- # return self.__dict__.has_key(key)
- #
- #def items(self):
- # return self.__dict__.items()
-
- def retrieve_info(self, QTL=False):
- assert self.dataset, "Dataset doesn't exist"
- if self.dataset.type == 'Publish':
- query = """
- SELECT
- PublishXRef.Id, Publication.PubMed_ID,
- Phenotype.Pre_publication_description, Phenotype.Post_publication_description, Phenotype.Original_description,
- Phenotype.Pre_publication_abbreviation, Phenotype.Post_publication_abbreviation,
- Phenotype.Lab_code, Phenotype.Submitter, Phenotype.Owner, Phenotype.Authorized_Users,
- Publication.Authors, Publication.Title, Publication.Abstract,
- Publication.Journal, Publication.Volume, Publication.Pages,
- Publication.Month, Publication.Year, PublishXRef.Sequence,
- Phenotype.Units, PublishXRef.comments
- FROM
- PublishXRef, Publication, Phenotype, PublishFreeze
- WHERE
- PublishXRef.Id = %s AND
- Phenotype.Id = PublishXRef.PhenotypeId AND
- Publication.Id = PublishXRef.PublicationId AND
- PublishXRef.InbredSetId = PublishFreeze.InbredSetId AND
- PublishFreeze.Id = %s
- """ % (self.name, self.dataset.id)
- traitInfo = g.db.execute(query).fetchone()
- #XZ, 05/08/2009: Xiaodong add this block to use ProbeSet.Id to find the probeset instead of just using ProbeSet.Name
- #XZ, 05/08/2009: to avoid the problem of same probeset name from different platforms.
- elif self.dataset.type == 'ProbeSet':
- display_fields_string = ', ProbeSet.'.join(self.dataset.display_fields)
- display_fields_string = 'ProbeSet.' + display_fields_string
- query = """
- SELECT %s
- FROM ProbeSet, ProbeSetFreeze, ProbeSetXRef
- WHERE
- ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id AND
- ProbeSetXRef.ProbeSetId = ProbeSet.Id AND
- ProbeSetFreeze.Name = '%s' AND
- ProbeSet.Name = '%s'
- """ % (display_fields_string, self.dataset.name, self.name)
- traitInfo = g.db.execute(query).fetchone()
- print("traitInfo is: ", pf(traitInfo))
- #XZ, 05/08/2009: We also should use Geno.Id to find marker instead of just using Geno.Name
- # to avoid the problem of same marker name from different species.
- elif self.dataset.type == 'Geno':
- display_fields_string = string.join(self.dataset.display_fields,',Geno.')
- display_fields_string = 'Geno.' + display_fields_string
- query = """
- SELECT %s
- FROM Geno, GenoFreeze, GenoXRef
- WHERE
- GenoXRef.GenoFreezeId = GenoFreeze.Id AND
- GenoXRef.GenoId = Geno.Id AND
- GenoFreeze.Name = '%s' AND
- Geno.Name = '%s'
- """ % (display_fields_string, self.dataset.name, self.name)
- traitInfo = g.db.execute(query).fetchone()
- print("traitInfo is: ", pf(traitInfo))
- else: #Temp type
- query = """SELECT %s FROM %s WHERE Name = %s
- """ % (string.join(self.dataset.display_fields,','),
- self.dataset.type, self.name)
- traitInfo = g.db.execute(query).fetchone()
-
-
- #self.cursor.execute(query)
- #traitInfo = self.cursor.fetchone()
- if traitInfo:
- self.haveinfo = True
-
- #XZ: assign SQL query result to trait attributes.
- for i, field in enumerate(self.dataset.display_fields):
- setattr(self, field, traitInfo[i])
-
- if self.dataset.type == 'Publish':
- self.confidential = 0
- if self.pre_publication_description and not self.pubmed_id:
- self.confidential = 1
-
- self.homologeneid = None
- if self.dataset.type == 'ProbeSet' and self.group and self.geneid:
- #XZ, 05/26/2010: From time to time, this query get error message because some geneid values in database are not number.
- #XZ: So I have to test if geneid is number before execute the query.
- #XZ: The geneid values in database should be cleaned up.
- try:
- junk = float(self.geneid)
- geneidIsNumber = 1
- except:
- geneidIsNumber = 0
-
- if geneidIsNumber:
- result = g.db.execute("""
- SELECT
- HomologeneId
- FROM
- Homologene, Species, InbredSet
- WHERE
- Homologene.GeneId =%s AND
- InbredSet.Name = '%s' AND
- InbredSet.SpeciesId = Species.Id AND
- Species.TaxonomyId = Homologene.TaxonomyId
- """, (self.geneid, self.group)).fetchone()
- #self.cursor.execute(query)
- #result = self.cursor.fetchone()
- else:
- result = None
-
- if result:
- self.homologeneid = result[0]
-
- if QTL:
- if self.dataset.type == 'ProbeSet' and not self.cellid:
- traitQTL = g.db.execute("""
- SELECT
- ProbeSetXRef.Locus, ProbeSetXRef.LRS, ProbeSetXRef.pValue, ProbeSetXRef.mean
- FROM
- ProbeSetXRef, ProbeSet
- WHERE
- ProbeSetXRef.ProbeSetId = ProbeSet.Id AND
- ProbeSet.Name = "%s" AND
- ProbeSetXRef.ProbeSetFreezeId =%s
- """, (self.name, self.dataset.id)).fetchone()
- #self.cursor.execute(query)
- #traitQTL = self.cursor.fetchone()
- if traitQTL:
- self.locus, self.lrs, self.pvalue, self.mean = traitQTL
- else:
- self.locus = self.lrs = self.pvalue = self.mean = ""
- if self.dataset.type == 'Publish':
- traitQTL = g.db.execute("""
- SELECT
- PublishXRef.Locus, PublishXRef.LRS
- FROM
- PublishXRef, PublishFreeze
- WHERE
- PublishXRef.Id = %s AND
- PublishXRef.InbredSetId = PublishFreeze.InbredSetId AND
- PublishFreeze.Id =%s
- """, (self.name, self.dataset.id)).fetchone()
- #self.cursor.execute(query)
- #traitQTL = self.cursor.fetchone()
- if traitQTL:
- self.locus, self.lrs = traitQTL
- else:
- self.locus = self.lrs = ""
- else:
- raise KeyError, `self.name`+' information is not found in the database.'
-
- def genHTML(self, formName = "", dispFromDatabase=0, privilege="guest", userName="Guest", authorized_users=""):
- if not self.haveinfo:
- self.retrieveInfo()
-
- if self.dataset.type == 'Publish':
- PubMedLink = ""
- if self.pubmed_id:
- PubMedLink = HT.Href(text="PubMed %d : " % self.pubmed_id,
- target = "_blank", url = webqtlConfig.PUBMEDLINK_URL % self.pubmed_id)
- else:
- PubMedLink = HT.Span("Unpublished : ", Class="fs15")
-
- if formName:
- setDescription2 = HT.Href(url="javascript:showDatabase3('%s','%s','%s','')" %
- (formName, self.dataset.name, self.name), Class = "fs14")
- else:
- setDescription2 = HT.Href(url="javascript:showDatabase2('%s','%s','')" %
- (self.dataset.name,self.name), Class = "fs14")
-
- if self.confidential and not webqtlUtil.hasAccessToConfidentialPhenotypeTrait(privilege=privilege, userName=userName, authorized_users=authorized_users):
- setDescription2.append('RecordID/%s - %s' % (self.name, self.pre_publication_description))
- else:
- setDescription2.append('RecordID/%s - %s' % (self.name, self.post_publication_description))
-
- #XZ 03/26/2011: Xiaodong comment out the following two lins as Rob asked. Need to check with Rob why in PublishXRef table, there are few row whose Sequence > 1.
- #if self.sequence > 1:
- # setDescription2.append(' btach %d' % self.sequence)
- if self.authors:
- a1 = string.split(self.authors,',')[0]
- while a1[0] == '"' or a1[0] == "'" :
- a1 = a1[1:]
- setDescription2.append(' by ')
- setDescription2.append(HT.Italic('%s, and colleagues' % a1))
- setDescription = HT.Span(PubMedLink, setDescription2)
-
- elif self.dataset.type == 'Temp':
- setDescription = HT.Href(text="%s" % (self.description),url="javascript:showDatabase2\
- ('%s','%s','')" % (self.dataset.name,self.name), Class = "fs14")
- setDescription = HT.Span(setDescription)
-
- elif self.dataset.type == 'Geno': # Genome DB only available for single search
- if formName:
- setDescription = HT.Href(text="Locus %s [Chr %s @ %s Mb]" % (self.name,self.chr,\
- '%2.3f' % self.mb),url="javascript:showDatabase3('%s','%s','%s','')" % \
- (formName, self.dataset.name, self.name), Class = "fs14")
- else:
- setDescription = HT.Href(text="Locus %s [Chr %s @ %s Mb]" % (self.name,self.chr,\
- '%2.3f' % self.mb),url="javascript:showDatabase2('%s','%s','')" % \
- (self.dataset.name,self.name), Class = "fs14")
-
- setDescription = HT.Span(setDescription)
-
- else:
- if self.cellid:
- if formName:
- setDescription = HT.Href(text="ProbeSet/%s/%s" % (self.name, self.cellid),url=\
- "javascript:showDatabase3('%s','%s','%s','%s')" % (formName, self.dataset.name,self.name,self.cellid), \
- Class = "fs14")
- else:
- setDescription = HT.Href(text="ProbeSet/%s/%s" % (self.name,self.cellid),url=\
- "javascript:showDatabase2('%s','%s','%s')" % (self.dataset.name,self.name,self.cellid), \
- Class = "fs14")
- else:
- if formName:
- setDescription = HT.Href(text="ProbeSet/%s" % self.name, url=\
- "javascript:showDatabase3('%s','%s','%s','')" % (formName, self.dataset.name,self.name), \
- Class = "fs14")
- else:
- setDescription = HT.Href(text="ProbeSet/%s" % self.name, url=\
- "javascript:showDatabase2('%s','%s','')" % (self.dataset.name,self.name), \
- Class = "fs14")
- if self.symbol and self.chr and self.mb:
- setDescription.append(' [')
- setDescription.append(HT.Italic('%s' % self.symbol,Class="cdg fwb"))
- setDescription.append(' on Chr %s @ %s Mb]' % (self.chr,self.mb))
- if self.description:
- setDescription.append(': %s' % self.description)
- if self.probe_target_description:
- setDescription.append('; %s' % self.probe_target_description)
- setDescription = HT.Span(setDescription)
-
- if self.dataset.type != 'Temp' and dispFromDatabase:
- setDescription.append( ' --- FROM : ')
- setDescription.append(self.dataset.genHTML(Class='cori'))
- return setDescription
-
- @property
- def description_fmt(self):
- '''Return a text formated description'''
- if self.description:
- formatted = self.description
- if self.probe_target_description:
- formatted += "; " + self.probe_target_description
- else:
- formatted = "Not available"
- return formatted.capitalize()
-
- @property
- def alias_fmt(self):
- '''Return a text formatted alias'''
- if self.alias:
- alias = string.replace(self.alias, ";", " ")
- alias = string.join(string.split(alias), ", ")
- return alias
-
-
- @property
- def location_fmt(self):
- '''Return a text formatted location
-
- While we're at it we set self.location in case we need it later (do we?)
-
- '''
-
- if self.chr and self.mb:
- self.location = 'Chr %s @ %s Mb' % (self.chr,self.mb)
- elif self.chr:
- self.location = 'Chr %s @ Unknown position' % (self.chr)
- else:
- self.location = 'Not available'
-
- fmt = self.location
- ##XZ: deal with direction
- if self.strand_probe == '+':
- fmt += (' on the plus strand ')
- elif self.strand_probe == '-':
- fmt += (' on the minus strand ')
-
- return fmt
-
-
- def get_database(self):
- """
- Returns the database, and the url referring to the database if it exists
-
- We're going to to return two values here, and we don't want to have to call this twice from
- the template. So it's not a property called from the template, but instead is called from the view
-
- """
- if self.cellid:
- self.cursor.execute("""
- select ProbeFreeze.Name from ProbeFreeze, ProbeSetFreeze
- where
- ProbeFreeze.Id = ProbeSetFreeze.ProbeFreezeId AND
- ProbeSetFreeze.Id = %d""" % thisTrait.dataset.id)
- probeDBName = self.cursor.fetchone()[0]
- return dict(name = probeDBName,
- url = None)
- else:
- return dict(name = self.dataset.fullname,
- url = webqtlConfig.INFOPAGEHREF % self.dataset.name)
-
- def calculate_correlation(self, values, method):
- """Calculate the correlation value and p value according to the method specified"""
-
- #ZS: This takes the list of values of the trait our selected trait is being correlated against and removes the values of the samples our trait has no value for
- #There's probably a better way of dealing with this, but I'll have to ask Christian
- updated_raw_values = []
- updated_values = []
- for i in range(len(values)):
- if values[i] != "None":
- updated_raw_values.append(self.raw_values[i])
- updated_values.append(values[i])
-
- self.raw_values = updated_raw_values
- values = updated_values
-
- if method == METHOD_SAMPLE_PEARSON or method == METHOD_LIT or method == METHOD_TISSUE_PEARSON:
- corr, nOverlap = webqtlUtil.calCorrelation(self.raw_values, values, len(values))
- else:
- corr, nOverlap = webqtlUtil.calCorrelationRank(self.raw_values, values, len(values))
-
- self.correlation = corr
- self.overlap = nOverlap
-
- if self.overlap < 3:
- self.p_value = 1.0
- else:
- #ZS - This is probably the wrong way to deal with this. Correlation values of 1.0 definitely exist (the trait correlated against itself), so zero division needs to br prevented.
- if abs(self.correlation) >= 1.0:
- self.p_value = 0.0
- else:
- ZValue = 0.5*log((1.0+self.correlation)/(1.0-self.correlation))
- ZValue = ZValue*sqrt(self.overlap-3)
- self.p_value = 2.0*(1.0 - reaper.normp(abs(ZValue)))