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authorzsloan2022-01-14 18:22:32 +0000
committerzsloan2022-01-14 18:22:32 +0000
commit68ac19153b128f60b660e11365e5fd4304c95300 (patch)
tree198e03522af43a2d41f3c02cf3785bcfd4635fc4 /wqflask/base/data_set.py
parentf588ad96ae5045499860fa6e2740e101ad4410d7 (diff)
parent9ab0c3b6cc146e1711f1478242d4198eed720e4c (diff)
downloadgenenetwork2-68ac19153b128f60b660e11365e5fd4304c95300.tar.gz
Merge branch 'testing' of github.com:genenetwork/genenetwork2 into feature/add_rqtl_pairscan
Diffstat (limited to 'wqflask/base/data_set.py')
-rw-r--r--wqflask/base/data_set.py187
1 files changed, 130 insertions, 57 deletions
diff --git a/wqflask/base/data_set.py b/wqflask/base/data_set.py
index 8906ab69..af248659 100644
--- a/wqflask/base/data_set.py
+++ b/wqflask/base/data_set.py
@@ -20,7 +20,7 @@
from dataclasses import dataclass
from dataclasses import field
from dataclasses import InitVar
-from typing import Optional, Dict
+from typing import Optional, Dict, List
from db.call import fetchall, fetchone, fetch1
from utility.logger import getLogger
from utility.tools import USE_GN_SERVER, USE_REDIS, flat_files, flat_file_exists, GN2_BASE_URL
@@ -39,6 +39,9 @@ from db import webqtlDatabaseFunction
from base import species
from base import webqtlConfig
from flask import Flask, g
+from base.webqtlConfig import TMPDIR
+from urllib.parse import urlparse
+from utility.tools import SQL_URI
import os
import math
import string
@@ -50,6 +53,8 @@ import requests
import gzip
import pickle as pickle
import itertools
+import hashlib
+import datetime
from redis import Redis
@@ -397,7 +402,8 @@ class DatasetGroup:
self.parlist = [maternal, paternal]
def get_study_samplelists(self):
- study_sample_file = locate_ignore_error(self.name + ".json", 'study_sample_lists')
+ study_sample_file = locate_ignore_error(
+ self.name + ".json", 'study_sample_lists')
try:
f = open(study_sample_file)
except:
@@ -423,8 +429,6 @@ class DatasetGroup:
if result is not None:
self.samplelist = json.loads(result)
else:
- logger.debug("Cache not hit")
-
genotype_fn = locate_ignore_error(self.name + ".geno", 'genotype')
if genotype_fn:
self.samplelist = get_group_samplelists.get_samplelist(
@@ -447,7 +451,6 @@ class DatasetGroup:
# genotype_1 is Dataset Object without parents and f1
# genotype_2 is Dataset Object with parents and f1 (not for intercross)
-
# reaper barfs on unicode filenames, so here we ensure it's a string
if self.genofile:
if "RData" in self.genofile: # ZS: This is a temporary fix; I need to change the way the JSON files that point to multiple genotype files are structured to point to other file types like RData
@@ -726,7 +729,6 @@ class DataSet:
data_results = self.chunk_dataset(query_results, len(sample_ids))
self.samplelist = sorted_samplelist
self.trait_data = data_results
-
def get_trait_data(self, sample_list=None):
if sample_list:
@@ -745,66 +747,75 @@ class DataSet:
and Species.name = '{}'
""".format(create_in_clause(self.samplelist), *mescape(self.group.species))
results = dict(g.db.execute(query).fetchall())
- sample_ids = [results[item] for item in self.samplelist]
+ sample_ids = [results.get(item)
+ for item in self.samplelist if item is not None]
# MySQL limits the number of tables that can be used in a join to 61,
# so we break the sample ids into smaller chunks
# Postgres doesn't have that limit, so we can get rid of this after we transition
chunk_size = 50
number_chunks = int(math.ceil(len(sample_ids) / chunk_size))
- trait_sample_data = []
- for sample_ids_step in chunks.divide_into_chunks(sample_ids, number_chunks):
- if self.type == "Publish":
- dataset_type = "Phenotype"
- else:
- dataset_type = self.type
- temp = ['T%s.value' % item for item in sample_ids_step]
- if self.type == "Publish":
- query = "SELECT {}XRef.Id,".format(escape(self.type))
- else:
- query = "SELECT {}.Name,".format(escape(dataset_type))
- data_start_pos = 1
- query += ', '.join(temp)
- query += ' FROM ({}, {}XRef, {}Freeze) '.format(*mescape(dataset_type,
- self.type,
- self.type))
-
- for item in sample_ids_step:
- query += """
- left join {}Data as T{} on T{}.Id = {}XRef.DataId
- and T{}.StrainId={}\n
- """.format(*mescape(self.type, item, item, self.type, item, item))
-
- if self.type == "Publish":
- query += """
- WHERE {}XRef.InbredSetId = {}Freeze.InbredSetId
- and {}Freeze.Name = '{}'
- and {}.Id = {}XRef.{}Id
- order by {}.Id
- """.format(*mescape(self.type, self.type, self.type, self.name,
- dataset_type, self.type, dataset_type, dataset_type))
- else:
- query += """
- WHERE {}XRef.{}FreezeId = {}Freeze.Id
- and {}Freeze.Name = '{}'
- and {}.Id = {}XRef.{}Id
- order by {}.Id
- """.format(*mescape(self.type, self.type, self.type, self.type,
- self.name, dataset_type, self.type, self.type, dataset_type))
- results = g.db.execute(query).fetchall()
- trait_sample_data.append(results)
+ cached_results = fetch_cached_results(self.name, self.type)
+ if cached_results is None:
+ trait_sample_data = []
+ for sample_ids_step in chunks.divide_into_chunks(sample_ids, number_chunks):
+ if self.type == "Publish":
+ dataset_type = "Phenotype"
+ else:
+ dataset_type = self.type
+ temp = ['T%s.value' % item for item in sample_ids_step]
+ if self.type == "Publish":
+ query = "SELECT {}XRef.Id,".format(escape(self.type))
+ else:
+ query = "SELECT {}.Name,".format(escape(dataset_type))
+ data_start_pos = 1
+ query += ', '.join(temp)
+ query += ' FROM ({}, {}XRef, {}Freeze) '.format(*mescape(dataset_type,
+ self.type,
+ self.type))
+
+ for item in sample_ids_step:
+ query += """
+ left join {}Data as T{} on T{}.Id = {}XRef.DataId
+ and T{}.StrainId={}\n
+ """.format(*mescape(self.type, item, item, self.type, item, item))
+
+ if self.type == "Publish":
+ query += """
+ WHERE {}XRef.InbredSetId = {}Freeze.InbredSetId
+ and {}Freeze.Name = '{}'
+ and {}.Id = {}XRef.{}Id
+ order by {}.Id
+ """.format(*mescape(self.type, self.type, self.type, self.name,
+ dataset_type, self.type, dataset_type, dataset_type))
+ else:
+ query += """
+ WHERE {}XRef.{}FreezeId = {}Freeze.Id
+ and {}Freeze.Name = '{}'
+ and {}.Id = {}XRef.{}Id
+ order by {}.Id
+ """.format(*mescape(self.type, self.type, self.type, self.type,
+ self.name, dataset_type, self.type, self.type, dataset_type))
- trait_count = len(trait_sample_data[0])
- self.trait_data = collections.defaultdict(list)
+ results = g.db.execute(query).fetchall()
+ trait_sample_data.append([list(result) for result in results])
- # put all of the separate data together into a dictionary where the keys are
- # trait names and values are lists of sample values
- for trait_counter in range(trait_count):
- trait_name = trait_sample_data[0][trait_counter][0]
- for chunk_counter in range(int(number_chunks)):
- self.trait_data[trait_name] += (
- trait_sample_data[chunk_counter][trait_counter][data_start_pos:])
+ trait_count = len(trait_sample_data[0])
+ self.trait_data = collections.defaultdict(list)
+
+ data_start_pos = 1
+ for trait_counter in range(trait_count):
+ trait_name = trait_sample_data[0][trait_counter][0]
+ for chunk_counter in range(int(number_chunks)):
+ self.trait_data[trait_name] += (
+ trait_sample_data[chunk_counter][trait_counter][data_start_pos:])
+
+ cache_dataset_results(
+ self.name, self.type, self.trait_data)
+ else:
+
+ self.trait_data = cached_results
class PhenotypeDataSet(DataSet):
@@ -1242,3 +1253,65 @@ def geno_mrna_confidentiality(ob):
if confidential:
return True
+
+
+def parse_db_url():
+ parsed_db = urlparse(SQL_URI)
+
+ return (parsed_db.hostname, parsed_db.username,
+ parsed_db.password, parsed_db.path[1:])
+
+
+def query_table_timestamp(dataset_type: str):
+ """function to query the update timestamp of a given dataset_type"""
+
+ # computation data and actions
+
+ fetch_db_name = parse_db_url()
+ query_update_time = f"""
+ SELECT UPDATE_TIME FROM information_schema.tables
+ WHERE TABLE_SCHEMA = '{fetch_db_name[-1]}'
+ AND TABLE_NAME = '{dataset_type}Data'
+ """
+
+ date_time_obj = g.db.execute(query_update_time).fetchone()[0]
+ return date_time_obj.strftime("%Y-%m-%d %H:%M:%S")
+
+
+def generate_hash_file(dataset_name: str, dataset_type: str, dataset_timestamp: str):
+ """given the trait_name generate a unique name for this"""
+ string_unicode = f"{dataset_name}{dataset_timestamp}".encode()
+ md5hash = hashlib.md5(string_unicode)
+ return md5hash.hexdigest()
+
+
+def cache_dataset_results(dataset_name: str, dataset_type: str, query_results: List):
+ """function to cache dataset query results to file
+ input dataset_name and type query_results(already processed in default dict format)
+ """
+ # data computations actions
+ # store the file path on redis
+
+ table_timestamp = query_table_timestamp(dataset_type)
+
+
+ file_name = generate_hash_file(dataset_name, dataset_type, table_timestamp)
+ file_path = os.path.join(TMPDIR, f"{file_name}.json")
+
+ with open(file_path, "w") as file_handler:
+ json.dump(query_results, file_handler)
+
+
+def fetch_cached_results(dataset_name: str, dataset_type: str):
+ """function to fetch the cached results"""
+
+ table_timestamp = query_table_timestamp(dataset_type)
+
+ file_name = generate_hash_file(dataset_name, dataset_type, table_timestamp)
+ file_path = os.path.join(TMPDIR, f"{file_name}.json")
+ try:
+ with open(file_path, "r") as file_handler:
+
+ return json.load(file_handler)
+ except FileNotFoundError:
+ pass