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authorzsloan2015-03-27 20:28:51 +0000
committerzsloan2015-03-27 20:28:51 +0000
commitd0911a04958a04042da02a334ccc528dae79cc17 (patch)
tree3c48e2e937c1dbeaf00a5697c87ed251afa5c8f1 /web/webqtl/intervalAnalyst/GeneUtil.py
parenta840ad18e1fe3db98a359a159e9b9b72367a2839 (diff)
downloadgenenetwork2-d0911a04958a04042da02a334ccc528dae79cc17.tar.gz
Removed everything from 'web' directory except genofiles and renamed the directory to 'genotype_files'
Diffstat (limited to 'web/webqtl/intervalAnalyst/GeneUtil.py')
-rwxr-xr-xweb/webqtl/intervalAnalyst/GeneUtil.py124
1 files changed, 0 insertions, 124 deletions
diff --git a/web/webqtl/intervalAnalyst/GeneUtil.py b/web/webqtl/intervalAnalyst/GeneUtil.py
deleted file mode 100755
index 43008ecf..00000000
--- a/web/webqtl/intervalAnalyst/GeneUtil.py
+++ /dev/null
@@ -1,124 +0,0 @@
-# Copyright (C) University of Tennessee Health Science Center, Memphis, TN.
-#
-# This program is free software: you can redistribute it and/or modify it
-# under the terms of the GNU Affero General Public License
-# as published by the Free Software Foundation, either version 3 of the
-# License, or (at your option) any later version.
-#
-# This program is distributed in the hope that it will be useful,
-# but WITHOUT ANY WARRANTY; without even the implied warranty of
-# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.
-# See the GNU Affero General Public License for more details.
-#
-# This program is available from Source Forge: at GeneNetwork Project
-# (sourceforge.net/projects/genenetwork/).
-#
-# Contact Drs. Robert W. Williams and Xiaodong Zhou (2010)
-# at rwilliams@uthsc.edu and xzhou15@uthsc.edu
-#
-#
-#
-# This module is used by GeneNetwork project (www.genenetwork.org)
-#
-# Created by GeneNetwork Core Team 2010/08/10
-#
-# Last updated by GeneNetwork Core Team 2010/10/20
-
-import string
-
-#Just return a list of dictionaries
-#each dictionary contains sub-dictionary
-def loadGenes(cursor, chrName, diffCol, startMb, endMb, webqtlDb =None, species='mouse'):
- #cursor.execute("desc GeneList")
- #results = cursor.fetchall()
- #fetchFields = map(lambda X:X[0], results)
- fetchFields = ['SpeciesId', 'Id', 'GeneSymbol', 'GeneDescription', 'Chromosome', 'TxStart', 'TxEnd',
- 'Strand', 'GeneID', 'NM_ID', 'kgID', 'GenBankID', 'UnigenID', 'ProteinID', 'AlignID',
- 'exonCount', 'exonStarts', 'exonEnds', 'cdsStart', 'cdsEnd']
-
- ##List All Species in the Gene Table
- speciesDict = {}
- cursor.execute("select Species.Name, GeneList.SpeciesId from Species, GeneList where \
- GeneList.SpeciesId = Species.Id group by GeneList.SpeciesId")
- results = cursor.fetchall()
- for item in results:
- speciesDict[item[0]] = item[1]
-
- ##List current Species and other Species
- speciesId = speciesDict[species]
- otherSpecies = map(lambda X: [X, speciesDict[X]], speciesDict.keys())
- otherSpecies.remove([species, speciesId])
-
- cursor.execute("""SELECT %s from GeneList
- where
- SpeciesId = %d AND Chromosome = '%s' AND
- ((TxStart > %f and TxStart <= %f) OR (TxEnd > %f and TxEnd <= %f))
- order by txStart
- """
- % (string.join(fetchFields, ", "), speciesId, chrName, startMb, endMb, startMb, endMb))
- results = cursor.fetchall()
- GeneList = []
-
- if results:
- for result in results:
- newdict = {}
- for j, item in enumerate(fetchFields):
- newdict[item] = result[j]
- #count SNPs if possible
- if diffCol and species=='mouse':
- cursor.execute("""
- select
- count(*) from BXDSnpPosition
- where
- Chr = '%s' AND Mb >= %2.6f AND Mb < %2.6f AND
- StrainId1 = %d AND StrainId2 = %d
- """ % (chrName, newdict["TxStart"], newdict["TxEnd"], diffCol[0], diffCol[1]))
- newdict["snpCount"] = cursor.fetchone()[0]
- newdict["snpDensity"] = newdict["snpCount"]/(newdict["TxEnd"]-newdict["TxStart"])/1000.0
- else:
- newdict["snpDensity"] = newdict["snpCount"] = 0
-
- try:
- newdict['GeneLength'] = 1000.0*(newdict['TxEnd'] - newdict['TxStart'])
- except:
- pass
-
- #load gene from other Species by the same name
- for item in otherSpecies:
- othSpec, othSpecId = item
- newdict2 = {}
-
- cursor.execute("SELECT %s from GeneList where SpeciesId = %d and geneSymbol= '%s' limit 1" %
- (string.join(fetchFields, ", "), othSpecId, newdict["GeneSymbol"]))
- resultsOther = cursor.fetchone()
- if resultsOther:
- for j, item in enumerate(fetchFields):
- newdict2[item] = resultsOther[j]
-
- #count SNPs if possible, could be a separate function
- if diffCol and othSpec == 'mouse':
- cursor.execute("""
- select
- count(*) from BXDSnpPosition
- where
- Chr = '%s' AND Mb >= %2.6f AND Mb < %2.6f AND
- StrainId1 = %d AND StrainId2 = %d
- """ % (chrName, newdict["TxStart"], newdict["TxEnd"], diffCol[0], diffCol[1]))
-
- newdict2["snpCount"] = cursor.fetchone()[0]
- newdict2["snpDensity"] = newdict2["snpCount"]/(newdict2["TxEnd"]-newdict2["TxStart"])/1000.0
- else:
- newdict2["snpDensity"] = newdict2["snpCount"] = 0
-
- try:
- newdict2['GeneLength'] = 1000.0*(newdict2['TxEnd'] - newdict2['TxStart'])
- except:
- pass
-
- newdict['%sGene' % othSpec] = newdict2
-
- GeneList.append(newdict)
-
- return GeneList
-
-