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author | Pjotr Prins | 2016-06-02 09:40:22 +0200 |
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committer | Pjotr Prins | 2016-06-02 09:40:22 +0200 |
commit | e241d27ccd3302632fec52043fc8b42125f4cfd7 (patch) | |
tree | 36d3f65ca9050beee1c5db0264cc6a3ac13ce771 /doc | |
parent | f0aadf83cf4a26c522887a89d4d09f9b4c01c704 (diff) | |
download | genenetwork2-e241d27ccd3302632fec52043fc8b42125f4cfd7.tar.gz |
Paper: addressing https://github.com/openjournals/joss-reviews/issues/25
1st par: "experimental data" could be fleshed out in 2-3 words for the biologist reader (is it SNPs, microarray data, NGS, Y2H or manually counted individuals?)
Diffstat (limited to 'doc')
-rw-r--r-- | doc/joss/2016/paper.md | 19 |
1 files changed, 11 insertions, 8 deletions
diff --git a/doc/joss/2016/paper.md b/doc/joss/2016/paper.md index 02fc6a65..a3eb4477 100644 --- a/doc/joss/2016/paper.md +++ b/doc/joss/2016/paper.md @@ -41,14 +41,17 @@ bibliography: paper.bib GeneNetwork (GN) is a free and open source (FOSS) framework for web-based genetics that can be deployed anywhere. GN allows biologists -to upload experimental data and map phenotypes interactively against -genotypes using tools, such as R/QTL [@Arends:2010] mapping, interval -mapping for model organisms and pylmm; an implementation of FaST-LMM -[@Lippert:2011] which is suitable for human populations and outbred -crosses, such as the mouse diversity outcross. Interactive D3 graphics -are included from R/qtlcharts and presentation-ready figures can be -generated. Recently we have added functionality for phenotype -correlation [@Wang:2016] and network analysis [@WGCNA:2008]. +to upload high-throughput experimental data, such as expression data +from microarrays and RNA-seq, and also `classic' phenotypes, such as +disease phenotypes. These phenotypes can be mapped interactively +against genotypes using embedded tools, such as R/QTL [@Arends:2010] +mapping, interval mapping for model organisms and pylmm; an +implementation of FaST-LMM [@Lippert:2011] which is more suitable for +human populations and outbred crosses, such as the mouse diversity +outcross. Interactive D3 graphics are included from R/qtlcharts and +presentation-ready figures can be generated. Recently we have added +functionality for phenotype correlation [@Wang:2016] and network +analysis [@WGCNA:2008]. -![Mouse LMM mapping example](qtl2.png) |