Merge branch 'testing' of github.com:genenetwork/genenetwork2 into feature/add_rqtl_pairscan

1 files changed, 1 insertions, 167 deletions

diff --git a/doc/API_readme.md b/doc/API_readme.md
index be6668dc..17d10e44 100644
--- a/doc/API_readme.md
+++ b/doc/API_readme.md
@@ -1,169 +1,3 @@
 # API Query Documentation #
----
-# Fetching Dataset/Trait info/data #
----
-## Fetch Species List ##
 
-To get a list of species with data available in GN (and their associated names and ids):
-```
-curl http://genenetwork.org/api/v_pre1/species
-[ { "FullName": "Mus musculus", "Id": 1, "Name": "mouse", "TaxonomyId": 10090 }, ... { "FullName": "Populus trichocarpa", "Id": 10, "Name": "poplar", "TaxonomyId": 3689 } ]
-```
-
-Or to get a single species info:
-```
-curl http://genenetwork.org/api/v_pre1/species/mouse
-``` 
-OR 
-```
-curl http://genenetwork.org/api/v_pre1/species/mouse.json
-```
-
-*For all queries where the last field is a user-specified name/ID, there will be the option to append a file format type. Currently there is only JSON (and it will default to JSON if none is provided), but other formats will be added later*
-
-## Fetch Groups/RISets ##
-
-This query can optionally filter by species:
-
-```
-curl http://genenetwork.org/api/v_pre1/groups (for all species)
-```
-OR
-```
-curl http://genenetwork.org/api/v_pre1/groups/mouse (for just mouse groups/RISets)
-[ { "DisplayName": "BXD", "FullName": "BXD RI Family", "GeneticType": "riset", "Id": 1, "MappingMethodId": "1", "Name": "BXD", "SpeciesId": 1, "public": 2 }, ... { "DisplayName": "AIL LGSM F34 and F39-43 (GBS)", "FullName": "AIL LGSM F34 and F39-43 (GBS)", "GeneticType": "intercross", "Id": 72, "MappingMethodId": "2", "Name": "AIL-LGSM-F34-F39-43-GBS", "SpeciesId": 1, "public": 2 } ]
-```
-
-## Fetch Genotypes for Group/RISet ##
-```
-curl http://genenetwork.org/api/v_pre1/genotypes/bimbam/BXD
-curl http://genenetwork.org/api/v_pre1/genotypes/BXD.bimbam
-```
-Returns a group's genotypes in one of several formats - bimbam, rqtl2, or geno (a format used by qtlreaper which is just a CSV file consisting of marker positions and genotypes)
-
-Rqtl2 genotype queries can also include the dataset name and will return a zip of the genotypes, phenotypes, and gene map (marker names/positions). For example:
-```
-curl http://genenetwork.org/api/v_pre1/genotypes/rqtl2/BXD/HC_M2_0606_P.zip
-```
-
-## Fetch Datasets ##
-```
-curl http://genenetwork.org/api/v_pre1/datasets/bxd
-```
-OR
-```
-curl http://genenetwork.org/api/v_pre1/datasets/mouse/bxd
-[ { "AvgID": 1, "CreateTime": "Fri, 01 Aug 2003 00:00:00 GMT", "DataScale": "log2", "FullName": "UTHSC/ETHZ/EPFL BXD Liver Polar Metabolites Extraction A, CD Cohorts (Mar 2017) log2", "Id": 1, "Long_Abbreviation": "BXDMicroArray_ProbeSet_August03", "ProbeFreezeId": 3, "ShortName": "Brain U74Av2 08/03 MAS5", "Short_Abbreviation": "Br_U_0803_M", "confidentiality": 0, "public": 0 }, ... { "AvgID": 3, "CreateTime": "Tue, 14 Aug 2018 00:00:00 GMT", "DataScale": "log2", "FullName": "EPFL/LISP BXD CD Liver Affy Mouse Gene 1.0 ST (Aug18) RMA", "Id": 859, "Long_Abbreviation": "EPFLMouseLiverCDRMAApr18", "ProbeFreezeId": 181, "ShortName": "EPFL/LISP BXD CD Liver Affy Mouse Gene 1.0 ST (Aug18) RMA", "Short_Abbreviation": "EPFLMouseLiverCDRMA0818", "confidentiality": 0, "public": 1 } ]
-```
-(I added the option to specify species just in case we end up with the same group name across multiple species at some point, though it's currently unnecessary)
-
-## Fetch Individual Dataset Info ##
-### For mRNA Assay/"ProbeSet" ###
-
-```
-curl http://genenetwork.org/api/v_pre1/dataset/HC_M2_0606_P
-```
-OR
-```
-curl http://genenetwork.org/api/v_pre1/dataset/bxd/HC_M2_0606_P```
-{ "confidential": 0, "data_scale": "log2", "dataset_type": "mRNA expression", "full_name": "Hippocampus Consortium M430v2 (Jun06) PDNN", "id": 112, "name": "HC_M2_0606_P", "public": 2, "short_name": "Hippocampus M430v2 BXD 06/06 PDNN", "tissue": "Hippocampus mRNA", "tissue_id": 9 }
-```
-(This also has the option to specify group/riset)
-
-### For "Phenotypes" (basically non-mRNA Expression; stuff like weight, sex, etc) ###
-For these traits, the query fetches publication info and takes the group and phenotype 'ID' as input. For example:
-```
-curl http://genenetwork.org/api/v_pre1/dataset/bxd/10001
-{ "dataset_type": "phenotype", "description": "Central nervous system, morphology: Cerebellum weight, whole, bilateral in adults of both sexes [mg]", "id": 10001, "name": "CBLWT2", "pubmed_id": 11438585, "title": "Genetic control of the mouse cerebellum: identification of quantitative trait loci modulating size and architecture", "year": "2001" }
-```
-
-## Fetch Sample Data for Dataset ##
-``` 
-curl http://genenetwork.org/api/v_pre1/sample_data/HSNIH-PalmerPublish.csv
-```
-
-Returns a CSV file with sample/strain names as the columns and trait IDs as rows
-
-## Fetch Sample Data for Single Trait ##
-```
-curl http://genenetwork.org/api/v_pre1/sample_data/HC_M2_0606_P/1436869_at
-[ { "data_id": 23415463, "sample_name": "129S1/SvImJ", "sample_name_2": "129S1/SvImJ", "se": 0.123, "value": 8.201 }, { "data_id": 23415463, "sample_name": "A/J", "sample_name_2": "A/J", "se": 0.046, "value": 8.413 }, { "data_id": 23415463, "sample_name": "AKR/J", "sample_name_2": "AKR/J", "se": 0.134, "value": 8.856 }, ... ]
-```
-
-## Fetch Trait List for Dataset ##
-```
-curl http://genenetwork.org/api/v_pre1/traits/HXBBXHPublish.json
-[ { "Additive": 0.0499967532467532, "Id": 10001, "LRS": 16.2831307029479, "Locus": "rs106114574", "PhenotypeId": 1449, "PublicationId": 319, "Sequence": 1 }, ... ]
-```
-
-Both JSON and CSV formats can be specified, with JSON as default. There is also an optional "ids_only" and "names_only" parameter that will only return a list of trait IDs or names, respectively.
-
-## Fetch Trait Info (Name, Description, Location, etc) ##
-### For mRNA Expression/"ProbeSet" ###
-```
-curl http://genenetwork.org/api/v_pre1/trait/HC_M2_0606_P/1436869_at
-{ "additive": -0.214087568058076, "alias": "HHG1; HLP3; HPE3; SMMCI; Dsh; Hhg1", "chr": "5", "description": "sonic hedgehog (hedgehog)", "id": 99602, "locus": "rs8253327", "lrs": 12.7711275309832, "mb": 28.457155, "mean": 9.27909090909091, "name": "1436869_at", "p_value": 0.306, "se": null, "symbol": "Shh" }
-```
-
-### For "Phenotypes" ###
-For phenotypes this just gets the  max LRS, its location, and additive effect (as calculated by qtlreaper)
-
-Since each group/riset only has one phenotype "dataset", this query takes either the group/riset name or the group/riset name + "Publish" (for example "BXDPublish", which is the dataset name in the DB) as input
-```
-curl http://genenetwork.org/api/v_pre1/trait/BXD/10001
-{ "additive": 2.39444435069444, "id": 4, "locus": "rs48756159", "lrs": 13.4974911471087 }
-```
-
----
-
-# Analyses #
----
-## Mapping ##
-Currently two mapping tools can be used - GEMMA and R/qtl. qtlreaper will be added later with Christian Fischer's RUST implementation - https://github.com/chfi/rust-qtlreaper
-
-Each method's query takes the following parameters respectively (more will be added):
-### GEMMA ###
-* trait_id (*required*) - ID for trait being mapped
-* db (*required*) - DB name for trait above (Short_Abbreviation listed when you query for datasets)
-* use_loco - Whether to use LOCO (leave one chromosome out) method (default = false)
-* maf - minor allele frequency (default = 0.01)
-
-Example query:
-```
-curl http://genenetwork.org/api/v_pre1/mapping?trait_id=10015&db=BXDPublish&method=gemma&use_loco=true
-```
-
-### R/qtl ###
-(See the R/qtl guide for information on some of these options - http://www.rqtl.org/manual/qtl-manual.pdf)
-* trait_id (*required*) - ID for trait being mapped
-* db (*required*) - DB name for trait above (Short_Abbreviation listed when you query for datasets)
-* rqtl_method - hk (default) | ehk | em | imp | mr | mr-imp | mr-argmax ; Corresponds to the "method" option for the R/qtl scanone function.
-* rqtl_model - normal (default) | binary | 2-part | np ; corresponds to the "model" option for the R/qtl scanone function
-* num_perm - number of permutations; 0 by default
-* control_marker - Name of marker to use as control; this relies on the user knowing the name of the marker they want to use as a covariate
-* interval_mapping - Whether to use interval mapping; "false" by default
-* pair_scan - *NYI*
-
-Example query:
-```
-curl http://genenetwork.org/api/v_pre1/mapping?trait_id=1418701_at&db=HC_M2_0606_P&method=rqtl&num_perm=100
-```
-
-Some combinations of methods/models may not make sense. The R/qtl manual should be referred to for any questions on its use (specifically the scanone function in this case)
-
-## Calculate Correlation ##
-Currently only Sample and Tissue correlations are implemented
-
-This query currently takes the following parameters (though more will be added):
-* trait_id (*required*) - ID for trait used for correlation
-* db (*required*) - DB name for the trait above (this is the Short_Abbreviation listed when you query for datasets)
-* target_db (*required*) - Target DB name to be correlated against
-* type - sample (default) | tissue
-* method - pearson (default) | spearman
-* return - Number of results to return (default = 500)
-
-Example query:
-```
-curl http://genenetwork.org/api/v_pre1/correlation?trait_id=1427571_at&db=HC_M2_0606_P&target_db=BXDPublish&type=sample&return_count=100
-[ { "#_strains": 6, "p_value": 0.004804664723032055, "sample_r": -0.942857142857143, "trait": 20511 }, { "#_strains": 6, "p_value": 0.004804664723032055, "sample_r": -0.942857142857143, "trait": 20724 }, { "#_strains": 12, "p_value": 1.8288943424888848e-05, "sample_r": -0.9233615170820528, "trait": 13536 }, { "#_strains": 7, "p_value": 0.006807187408935392, "sample_r": 0.8928571428571429, "trait": 10157 }, { "#_strains": 7, "p_value": 0.006807187408935392, "sample_r": -0.8928571428571429, "trait": 20392 }, ... ]
-```
+This document has moved to [gn-docs](https://github.com/genenetwork/gn-docs/blob/master/api/GN2-REST-API.md)!