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{% extends "layout.html" %}
{% block content %}
{{ message | safe }}
<h3> <u>R</u>elationship with <u>A</u>ddiction <u>T</u>hrough <u>S</u>earches of <u>Pub</u>Med </span></a>
</h3>
<table>
<tr><td >
<p> RatsPub searches PubMed to find <i>sentences</i> that contain the query terms (i.e., gene symbols) and <a href="https://github.com/chen42/RatsPub/blob/master/ratspub_keywords.py">drug addiction-related keywords</a>. These gene-keyword relationships are presented as an interactive graph that can efficiently answer the question <b>"What do we know about these genes and addiction?". </b> Data from <a href="https://www.ebi.ac.uk/gwas/">EBI GWAS catalog </a>are also included in the search. The graph has many interactive elements. For example, clicking gene names will launch a new search for sentences containing the target gene and 200 addiction-related genes. A tabular view is also available. </b>
<p>Up to 100 gene symbols can be entered in the box below. Gene symbols can be separated by either a space or a semicolon. Aliases will <i>not</i> be automatically included because the large number of false matches associated with gene synonyms retrieved from databases.
<b> {%if "name" in session %}
{{session['name']}}, your previous searches are <a href="/userarchive">archived </a> for faster retrival.</a>
{% else %}
Please sign in to save your searches.
{% endif %}
</b>
</td>
<td >
<div class='img'><img src="/static/ratspub.png" class="img-fluid">
</td>
</tr>
</table>
<a>
<b> Example: </b><a href=http://rats.pub/progress?type=GWAS&type=addiction&type=drug&type=brain&type=stress&type=psychiatric&type=function&query=Rgma+Nrxn3+Chrna3>Rgma Nrxn3 Chrna3</a><p>
<form action="/progress">
<div class="form-group row">
<div class="col-sm-10">
<strong>Please choose keyword categories to be included in the search:</strong>
<label>
<input type="checkbox" name="type" value="GWAS" checked> Human GWAS
<input type="checkbox" name="type" value="addiction" checked> Addiction Stage
<input type="checkbox" name="type" value="drug" checked> Drugs
<input type="checkbox" name="type" value="brain" checked> Brain Region
<input type="checkbox" name="type" value="stress" checked> Stress
<input type="checkbox" name="type" value="psychiatric" checked> Psychiatric Diseases
<input type="checkbox" name="type" value="function" checked> Function
</label>
</div>
<textarea name="query" class="form-control form-control-lg" type="search" row="3" id="searchform">
</textarea>
<button type="submit" class="btn btn-primary">Search</button>
</div>
</form>
{% endblock %}
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