From 17deca2d54827a00df3ea4d98df700fc2b8ed777 Mon Sep 17 00:00:00 2001
From: xiangzhou
Date: Sat, 20 Sep 2014 10:17:34 -0400
Subject: initial upload, version 0.95alpha
---
lm.h | 74 ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
1 file changed, 74 insertions(+)
create mode 100644 lm.h
(limited to 'lm.h')
diff --git a/lm.h b/lm.h
new file mode 100644
index 0000000..84a0322
--- /dev/null
+++ b/lm.h
@@ -0,0 +1,74 @@
+/*
+ Genome-wide Efficient Mixed Model Association (GEMMA)
+ Copyright (C) 2011 Xiang Zhou
+
+ This program is free software: you can redistribute it and/or modify
+ it under the terms of the GNU General Public License as published by
+ the Free Software Foundation, either version 3 of the License, or
+ (at your option) any later version.
+
+ This program is distributed in the hope that it will be useful,
+ but WITHOUT ANY WARRANTY; without even the implied warranty of
+ MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+ GNU General Public License for more details.
+
+ You should have received a copy of the GNU General Public License
+ along with this program. If not, see .
+ */
+
+#ifndef __LM_H__
+#define __LM_H__
+
+#include "gsl/gsl_vector.h"
+#include "gsl/gsl_matrix.h"
+
+
+#ifdef FORCE_FLOAT
+#include "param_float.h"
+#include "io_float.h"
+#else
+#include "param.h"
+#include "io.h"
+#endif
+
+using namespace std;
+
+
+class LM {
+
+public:
+ // IO related parameters
+ int a_mode; //analysis mode, 50+1/2/3/4 for Frequentist tests
+ size_t d_pace; //display pace
+
+ string file_bfile;
+ string file_geno;
+ string file_out;
+
+ string file_gene;
+
+ // Summary statistics
+ size_t ni_total, ni_test; //number of individuals
+ size_t ns_total, ns_test; //number of snps
+ size_t ng_total, ng_test; //number of genes
+ size_t n_cvt;
+ double time_opt; //time spent
+
+ vector indicator_idv; //indicator for individuals (phenotypes), 0 missing, 1 available for analysis
+ vector indicator_snp; //sequence indicator for SNPs: 0 ignored because of (a) maf, (b) miss, (c) non-poly; 1 available for analysis
+
+ vector snpInfo; //record SNP information
+
+ // Not included in PARAM
+ vector sumStat; //Output SNPSummary Data
+
+ // Main functions
+ void CopyFromParam (PARAM &cPar);
+ void CopyToParam (PARAM &cPar);
+ void AnalyzeGene (const gsl_matrix *W, const gsl_vector *x);
+ void AnalyzePlink (const gsl_matrix *W, const gsl_vector *y);
+ void AnalyzeBimbam (const gsl_matrix *W, const gsl_vector *y);
+ void WriteFiles ();
+};
+void MatrixCalcLmLR (const gsl_matrix *X, const gsl_vector *y, vector > &pos_loglr);
+#endif
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