From 1259ed80a7f60a9f7ba82f3751990ac24a8e9436 Mon Sep 17 00:00:00 2001 From: jgart Date: Wed, 24 Nov 2021 00:39:40 -0500 Subject: Add citation for Shapiro-Wilk Test --- topics/quality-control/qc-checks.gmi | 13 +++++++++++++ 1 file changed, 13 insertions(+) (limited to 'topics/quality-control') diff --git a/topics/quality-control/qc-checks.gmi b/topics/quality-control/qc-checks.gmi index 30236e1..713fa0b 100644 --- a/topics/quality-control/qc-checks.gmi +++ b/topics/quality-control/qc-checks.gmi @@ -58,3 +58,16 @@ phenotypes. -- Rob ``` + +``` +QTL analysis was performed in F2 mice using the R package R/qtl +(RRID:SCR_009085) as previously described.11,29,42 Quality checking +of genotypes and QTL analysis were performed in R (https://www.r- +project.org/) using R/bestNormalize (https://github.com/petersonR/ +bestNormalize) and R/qtl.42 Phenotypes were assessed for normality +using the Shapiro–Wilk Test. Because some of the data residuals devi- +ated significantly from normality, we used the orderNorm function to +perform Ordered Quantile normalization43 on all phenotypes. QTL +-- +A quantitative trait variant in Gabra2 underlies increased methamphetamine stimulant sensitivity +``` -- cgit v1.2.3