From 31d4e89a32e2eb9c540b2f35728f26d518c06c0c Mon Sep 17 00:00:00 2001 From: Pjotr Prins Date: Wed, 28 Aug 2024 10:22:29 +0200 Subject: gemma-wrapper: comment on GRM reduce --- topics/lmms/gemma/permutations.gmi | 2 ++ 1 file changed, 2 insertions(+) (limited to 'topics/lmms/gemma/permutations.gmi') diff --git a/topics/lmms/gemma/permutations.gmi b/topics/lmms/gemma/permutations.gmi index 9559366..3e2326d 100644 --- a/topics/lmms/gemma/permutations.gmi +++ b/topics/lmms/gemma/permutations.gmi @@ -351,6 +351,8 @@ So, the idea is to rerun permutations with the small set, but with the reduced G The interesting bit is that GEMMA requires input of phenotypes, but does not use them to compute the GRM. +After giving it some thought we want GRM reduction to work in production GN because of the speed benefit. That means modifying gemma-wrapper to take a list of genometypes as input - and we'll output that with GN. It is a good idea anyhow because it can give us some improved error feedback down the line. + WIP ## Dealing with epoch -- cgit v1.2.3