From f46ed96a01617514547da4636b6121fadc5f2326 Mon Sep 17 00:00:00 2001 From: jgart Date: Wed, 24 Nov 2021 00:05:03 -0500 Subject: Add Shapiro-Wilk Test QC Check scipy has an implementation --- topics/quality-control/qc-checks.gmi | 19 +++++++++++++++++++ 1 file changed, 19 insertions(+) diff --git a/topics/quality-control/qc-checks.gmi b/topics/quality-control/qc-checks.gmi index f2e47fd..30236e1 100644 --- a/topics/quality-control/qc-checks.gmi +++ b/topics/quality-control/qc-checks.gmi @@ -39,3 +39,22 @@ is allowed into the GeneNetwork will be 22,000 entries. 9. There should be no trailing spaces in data cells. 10. Entries should have the same capitalization style. + +11. Assesing Phenotypes for normality with Shapiro-Wilk Test. + +https://docs.scipy.org/doc/scipy/reference/generated/scipy.stats.shapiro.html +https://vedexcel.com/how-to-perform-a-shapiro-wilk-test-in-python/ + +``` +Here is a simple QC procedure we may want to consider that was used by +Megan and Camron in a recent paper that I have attached. + + +Phenotypes were assessed for normality using the Shapiro–Wilk Test. Because +some of the data residuals devi- ated significantly from normality, we used +the orderNorm function to perform Ordered Quantile normalization43 on all +phenotypes. + +-- +Rob +``` -- cgit v1.2.3