From e07e5e26a55e613c444d0c9b3fb2cea21011b194 Mon Sep 17 00:00:00 2001 From: Rob Williams Date: Mon, 18 Apr 2022 13:41:15 -0500 Subject: Create Effect size for GEMMA is a MUST --- issues/Effect size for GEMMA is a MUST | 8 ++++++++ 1 file changed, 8 insertions(+) create mode 100644 issues/Effect size for GEMMA is a MUST diff --git a/issues/Effect size for GEMMA is a MUST b/issues/Effect size for GEMMA is a MUST new file mode 100644 index 0000000..973e21a --- /dev/null +++ b/issues/Effect size for GEMMA is a MUST @@ -0,0 +1,8 @@ +To: @Zach, @Pjotr +From: robwwilliams +Regarding: Getting a readout of effect size and polarity of effect from GEMMA +Request Type: New feature for GEMMA, User requires these data + +Main Message: Let's Just Do It. Can be done as a kludge. Just plot the beta of the regression equation of the SNP status (ususally two or three states codes as 0, 1, 2 or -1,0, +1) against the phenotype. +The slope is roughly the effect size. This is good enough for most users. The only got-you is slight inflation of due to kinship structure and the Beavis effect when the sample size is low. +QUESTION—can I upload an image from Amelie Baud's talk on effect size? -- cgit v1.2.3