This is a microRNA data set generated using the Affymetrix Genechip miRNA 4.0 array (see http://media.affymetrix.com/support/technical/datasheets/miRNA_4-0_and_4-1_datasheet.pdf).

The data set provides 3222 estimates of expression (mainly for mi-RNAs) for 45 retinas from C57BL/6J (B6 cases B6.01 to B6.17), DBA/2J (cases D2.01 to D2.16), and DBA/2J with a wildtype Gpnmb allele (D2GP.01 to D2GP.12). Cases range in age from 30 to 576 days and include both sexes.

We are using this data set in combination with the conventional Mouse Gene 1.0ST array to study normal and glaucomatous changes in gene expression as a function of age. 

Please contact Lu Lu (lulu@uthsc.edu), Robert W. Williams  (rwilliams@uthsc.edu), or Junming Yue (jyue@uthsc.edu).

Supported in part by Research to Prevent Blindness.