NHLBI BXD Young Adult Heart CD CMS RNA-Seq (Nov20) TMP Log2
About the cases used to generate this set of data:
The study included 64 mice (~6 month) from B6, D2, and 32 advanced intercross BXD strains (about 2 mice per strain). All mice were fed on chow diet (CD) and treated with chronic mild stress (CMS). All procedures were approved by the UTHSC Institutional Animal Care and Use Committee.
Chronic Mild Stress (CMS)
During a period of 7 weeks, mice received 2 disturbances per day. These consisted of being exposed to wet bedding for 1 hour, 1 cm of water in the bottom of the cage with no bedding for 1 hour, no bedding for 1 hour, confinement in a 3 × 3 × 3 cm plastic box for 15 minutes, tilted cage at 45º for 1 hour, and exposure to foreign mouse or fox urine odor for 1 hour. The other stressor was a complete phase shift in the light:dark cycle over each weekend. Disruption of the light cycle (lights constantly on) occurred over the weekend (starting Friday 11:00 am) with the light cycle resuming at 11 am on Monday (lights off). The schedule was repeated weekly over the duration of the study.
The table of samples that are finally used for this study.
Index |
Sample ID |
Case id |
Strain |
Fuyi_Sex_Final |
Sac age/Day |
Tissue |
Diet |
Treatment |
1 |
C100 |
090215.15 |
BXD68 |
F |
185 |
Heart |
Chow diet |
CMS |
2 |
C101 |
090215.16 |
BXD48 |
F |
171 |
Heart |
Chow diet |
CMS |
3 |
C102 |
090215.20 |
BXD79 |
F |
162 |
Heart |
Chow diet |
CMS |
4 |
C103 |
090215.21 |
BXD63 |
F |
169 |
Heart |
Chow diet |
CMS |
5 |
C104 |
090215.24 |
BXD32 |
F |
188 |
Heart |
Chow diet |
CMS |
6 |
C105 |
090215.28 |
BXD63 |
F |
169 |
Heart |
Chow diet |
CMS |
7 |
C10 |
CMS102816.14 |
BXD77 |
F |
124 |
Heart |
Chow diet |
CMS |
8 |
C112 |
CMS032917.33 |
BXD70 |
F |
162 |
Heart |
Chow diet |
CMS |
9 |
C118 |
CMS082917.05 |
BXD77 |
F |
196 |
Heart |
Chow diet |
CMS |
10 |
C11 |
CMS102816.15 |
BXD73b |
F |
163 |
Heart |
Chow diet |
CMS |
11 |
C13 |
CMS102816.17 |
BXD100 |
F |
139 |
Heart |
Chow diet |
CMS |
12 |
C14 |
CMS102816.18 |
BXD43 |
F |
155 |
Heart |
Chow diet |
CMS |
13 |
C15 |
CMS102816.19 |
BXD83 |
F |
168 |
Heart |
Chow diet |
CMS |
14 |
C17 |
CMS102816.21 |
BXD65 |
F |
163 |
Heart |
Chow diet |
CMS |
15 |
C19 |
CMS102816.05 |
DBA/2J |
F |
156 |
Heart |
Chow diet |
CMS |
16 |
C1 |
CMS082817.05 |
BXD48 |
F |
174 |
Heart |
Chow diet |
CMS |
17 |
C21 |
CMS102816.07 |
DBA/2J |
F |
156 |
Heart |
Chow diet |
CMS |
18 |
C23 |
CMS102816.09 |
C57BL/6J |
F |
159 |
Heart |
Chow diet |
CMS |
19 |
C25 |
CMS102816.11 |
BXD100 |
F |
139 |
Heart |
Chow diet |
CMS |
20 |
C28 |
CMS102716.16 |
BXD77 |
F |
123 |
Heart |
Chow diet |
CMS |
21 |
C2 |
CMS083017.19 |
BXD24 |
F |
171 |
Heart |
Chow diet |
CMS |
22 |
C30 |
CMS102716.19 |
BXD73a |
F |
121 |
Heart |
Chow diet |
CMS |
23 |
C31 |
CMS102716.20 |
BXD50 |
F |
161 |
Heart |
Chow diet |
CMS |
24 |
C32 |
CMS102716.01 |
BXD83 |
F |
167 |
Heart |
Chow diet |
CMS |
25 |
C34 |
CMS102716.10 |
BXD43 |
F |
144 |
Heart |
Chow diet |
CMS |
26 |
C35 |
CMS102716.12 |
BXD62 |
F |
144 |
Heart |
Chow diet |
CMS |
27 |
C36 |
CMS102716.03 |
BXD73a |
F |
121 |
Heart |
Chow diet |
CMS |
28 |
C38 |
CMS102716.06 |
BXD34 |
M |
157 |
Heart |
Chow diet |
CMS |
29 |
C39 |
CMS102716.07 |
BXD24 |
F |
157 |
Heart |
Chow diet |
CMS |
30 |
C3 |
CMS083017.18 |
BXD87 |
F |
174 |
Heart |
Chow diet |
CMS |
31 |
C40 |
CMS102716.08 |
BXD60 |
F |
155 |
Heart |
Chow diet |
CMS |
32 |
C41 |
CMS102716.09 |
BXD60 |
F |
142 |
Heart |
Chow diet |
CMS |
33 |
C44 |
CMS033017.25 |
BXD78 |
F |
163 |
Heart |
Chow diet |
CMS |
34 |
C45 |
CMS032817.28 |
BXD66 |
F |
168 |
Heart |
Chow diet |
CMS |
35 |
C46 |
CMS032817.23 |
BXD86 |
F |
179 |
Heart |
Chow diet |
CMS |
36 |
C47 |
CMS082817.24 |
BXD51 |
F |
186 |
Heart |
Chow diet |
CMS |
37 |
C48 |
CMS082817.14 |
BXD65 |
F |
182 |
Heart |
Chow diet |
CMS |
38 |
C49 |
CMS082817.07 |
BXD44 |
F |
202 |
Heart |
Chow diet |
CMS |
39 |
C56 |
CMS102716.13 |
BXD77 |
F |
151 |
Heart |
Chow diet |
CMS |
40 |
C60 |
CMS032917.33 |
BXD70 |
F |
162 |
Heart |
Chow diet |
CMS |
41 |
C61 |
CMS032917.29 |
BXD71 |
F |
162 |
Heart |
Chow diet |
CMS |
42 |
C62 |
CMS032917.26 |
BXD87 |
F |
173 |
Heart |
Chow diet |
CMS |
43 |
C63 |
CMS032917.22 |
BXD71 |
F |
170 |
Heart |
Chow diet |
CMS |
44 |
C64 |
CMS083017.07 |
BXD69 |
F |
202 |
Heart |
Chow diet |
CMS |
45 |
C65 |
CMS082917.19 |
BXD44 |
F |
182 |
Heart |
Chow diet |
CMS |
46 |
C66 |
CMS030716.03 |
BXD101 |
F |
196 |
Heart |
Chow diet |
CMS |
47 |
C67 |
CMS030716.06 |
BXD69 |
F |
193 |
Heart |
Chow diet |
CMS |
48 |
C68 |
CMS030716.12 |
BXD68 |
F |
166 |
Heart |
Chow diet |
CMS |
49 |
C69 |
CMS030716.13 |
BXD55 |
F |
166 |
Heart |
Chow diet |
CMS |
50 |
C70 |
CMS030716.18 |
BXD40 |
F |
182 |
Heart |
Chow diet |
CMS |
51 |
C71 |
CMS030716.19 |
BXD40 |
F |
182 |
Heart |
Chow diet |
CMS |
52 |
C73 |
CMS030716.32 |
BXD101 |
F |
196 |
Heart |
Chow diet |
CMS |
53 |
C75 |
CMS030916.11 |
BXD79 |
F |
167 |
Heart |
Chow diet |
CMS |
54 |
C76 |
CMS030916.14 |
BXD48a |
F |
168 |
Heart |
Chow diet |
CMS |
55 |
C77 |
CMS030916.20 |
BXD65b |
F |
190 |
Heart |
Chow diet |
CMS |
56 |
C79 |
CMS030916.23 |
BXD65b |
F |
182 |
Heart |
Chow diet |
CMS |
57 |
C80 |
CMS030916.28 |
BXD66 |
F |
162 |
Heart |
Chow diet |
CMS |
58 |
C81 |
CMS030916.32 |
BXD86 |
F |
193 |
Heart |
Chow diet |
CMS |
59 |
C84 |
CMS102816.03 |
C57BL/6J |
F |
159 |
Heart |
Chow diet |
CMS |
60 |
C85 |
CMS102716.11 |
BXD34 |
F |
157 |
Heart |
Chow diet |
CMS |
61 |
C96 |
090215.02 |
BXD62 |
F |
137 |
Heart |
Chow diet |
CMS |
62 |
C97 |
090215.05 |
BXD75 |
F |
180 |
Heart |
Chow diet |
CMS |
63 |
C98 |
090215.06 |
BXD32 |
F |
188 |
Heart |
Chow diet |
CMS |
64 |
C99 |
090215.09 |
BXD75 |
F |
180 |
Heart |
Chow diet |
CMS |