NHLBI BXD Young Adult Heart CD CMS RNA-Seq (Nov20) TMP Log2

About the cases used to generate this set of data:

The study included 64 mice (~6 month) from B6, D2, and 32 advanced intercross BXD strains (about 2 mice per strain). All mice were fed on chow diet (CD) and treated with chronic mild stress (CMS). All procedures were approved by the UTHSC Institutional Animal Care and Use Committee.

 

Chronic Mild Stress (CMS)

During a period of 7 weeks, mice received 2 disturbances per day. These consisted of being exposed to wet bedding for 1 hour, 1 cm of water in the bottom of the cage with no bedding for 1 hour, no bedding for 1 hour, confinement in a 3 × 3 × 3 cm plastic box for 15 minutes, tilted cage at 45º for 1 hour, and exposure to foreign mouse or fox urine odor for 1 hour. The other stressor was a complete phase shift in the light:dark cycle over each weekend. Disruption of the light cycle (lights constantly on) occurred over the weekend (starting Friday 11:00 am) with the light cycle resuming at 11 am on Monday (lights off). The schedule was repeated weekly over the duration of the study.

 

 

The table of samples that are finally used for this study.

Index

Sample ID

Case id

Strain

Fuyi_Sex_Final

Sac age/Day

Tissue

Diet

Treatment

1

C100

090215.15

BXD68

F

185

Heart

Chow diet

CMS

2

C101

090215.16

BXD48

F

171

Heart

Chow diet

CMS

3

C102

090215.20

BXD79

F

162

Heart

Chow diet

CMS

4

C103

090215.21

BXD63

F

169

Heart

Chow diet

CMS

5

C104

090215.24

BXD32

F

188

Heart

Chow diet

CMS

6

C105

090215.28

BXD63

F

169

Heart

Chow diet

CMS

7

C10

CMS102816.14

BXD77

F

124

Heart

Chow diet

CMS

8

C112

CMS032917.33

BXD70

F

162

Heart

Chow diet

CMS

9

C118

CMS082917.05

BXD77

F

196

Heart

Chow diet

CMS

10

C11

CMS102816.15

BXD73b

F

163

Heart

Chow diet

CMS

11

C13

CMS102816.17

BXD100

F

139

Heart

Chow diet

CMS

12

C14

CMS102816.18

BXD43

F

155

Heart

Chow diet

CMS

13

C15

CMS102816.19

BXD83

F

168

Heart

Chow diet

CMS

14

C17

CMS102816.21

BXD65

F

163

Heart

Chow diet

CMS

15

C19

CMS102816.05

DBA/2J

F

156

Heart

Chow diet

CMS

16

C1

CMS082817.05

BXD48

F

174

Heart

Chow diet

CMS

17

C21

CMS102816.07

DBA/2J

F

156

Heart

Chow diet

CMS

18

C23

CMS102816.09

C57BL/6J

F

159

Heart

Chow diet

CMS

19

C25

CMS102816.11

BXD100

F

139

Heart

Chow diet

CMS

20

C28

CMS102716.16

BXD77

F

123

Heart

Chow diet

CMS

21

C2

CMS083017.19

BXD24

F

171

Heart

Chow diet

CMS

22

C30

CMS102716.19

BXD73a

F

121

Heart

Chow diet

CMS

23

C31

CMS102716.20

BXD50

F

161

Heart

Chow diet

CMS

24

C32

CMS102716.01

BXD83

F

167

Heart

Chow diet

CMS

25

C34

CMS102716.10

BXD43

F

144

Heart

Chow diet

CMS

26

C35

CMS102716.12

BXD62

F

144

Heart

Chow diet

CMS

27

C36

CMS102716.03

BXD73a

F

121

Heart

Chow diet

CMS

28

C38

CMS102716.06

BXD34

M

157

Heart

Chow diet

CMS

29

C39

CMS102716.07

BXD24

F

157

Heart

Chow diet

CMS

30

C3

CMS083017.18

BXD87

F

174

Heart

Chow diet

CMS

31

C40

CMS102716.08

BXD60

F

155

Heart

Chow diet

CMS

32

C41

CMS102716.09

BXD60

F

142

Heart

Chow diet

CMS

33

C44

CMS033017.25

BXD78

F

163

Heart

Chow diet

CMS

34

C45

CMS032817.28

BXD66

F

168

Heart

Chow diet

CMS

35

C46

CMS032817.23

BXD86

F

179

Heart

Chow diet

CMS

36

C47

CMS082817.24

BXD51

F

186

Heart

Chow diet

CMS

37

C48

CMS082817.14

BXD65

F

182

Heart

Chow diet

CMS

38

C49

CMS082817.07

BXD44

F

202

Heart

Chow diet

CMS

39

C56

CMS102716.13

BXD77

F

151

Heart

Chow diet

CMS

40

C60

CMS032917.33

BXD70

F

162

Heart

Chow diet

CMS

41

C61

CMS032917.29

BXD71

F

162

Heart

Chow diet

CMS

42

C62

CMS032917.26

BXD87

F

173

Heart

Chow diet

CMS

43

C63

CMS032917.22

BXD71

F

170

Heart

Chow diet

CMS

44

C64

CMS083017.07

BXD69

F

202

Heart

Chow diet

CMS

45

C65

CMS082917.19

BXD44

F

182

Heart

Chow diet

CMS

46

C66

CMS030716.03

BXD101

F

196

Heart

Chow diet

CMS

47

C67

CMS030716.06

BXD69

F

193

Heart

Chow diet

CMS

48

C68

CMS030716.12

BXD68

F

166

Heart

Chow diet

CMS

49

C69

CMS030716.13

BXD55

F

166

Heart

Chow diet

CMS

50

C70

CMS030716.18

BXD40

F

182

Heart

Chow diet

CMS

51

C71

CMS030716.19

BXD40

F

182

Heart

Chow diet

CMS

52

C73

CMS030716.32

BXD101

F

196

Heart

Chow diet

CMS

53

C75

CMS030916.11

BXD79

F

167

Heart

Chow diet

CMS

54

C76

CMS030916.14

BXD48a

F

168

Heart

Chow diet

CMS

55

C77

CMS030916.20

BXD65b

F

190

Heart

Chow diet

CMS

56

C79

CMS030916.23

BXD65b

F

182

Heart

Chow diet

CMS

57

C80

CMS030916.28

BXD66

F

162

Heart

Chow diet

CMS

58

C81

CMS030916.32

BXD86

F

193

Heart

Chow diet

CMS

59

C84

CMS102816.03

C57BL/6J

F

159

Heart

Chow diet

CMS

60

C85

CMS102716.11

BXD34

F

157

Heart

Chow diet

CMS

61

C96

090215.02

BXD62

F

137

Heart

Chow diet

CMS

62

C97

090215.05

BXD75

F

180

Heart

Chow diet

CMS

63

C98

090215.06

BXD32

F

188

Heart

Chow diet

CMS

64

C99

090215.09

BXD75

F

180

Heart

Chow diet

CMS