GWAS for expression in aortas of F1 offspring of inbred strains crossed with C57BL/6J carrying ApoE-Leiden and CETP transgenes fed chow diet for 8 weeks followed by Western diet for 16 weeks
diff --git a/general/datasets/UCLA_CXB_Aor_Jan16/platform.rtf b/general/datasets/UCLA_CXB_Aor_Jan16/platform.rtf new file mode 100644 index 0000000..41439e8 --- /dev/null +++ b/general/datasets/UCLA_CXB_Aor_Jan16/platform.rtf @@ -0,0 +1 @@ +GPL11180 HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate
diff --git a/general/datasets/UCLA_CXB_Aor_Jan16/specifics.rtf b/general/datasets/UCLA_CXB_Aor_Jan16/specifics.rtf new file mode 100644 index 0000000..20dd05b --- /dev/null +++ b/general/datasets/UCLA_CXB_Aor_Jan16/specifics.rtf @@ -0,0 +1 @@ +Group CXB \ No newline at end of file diff --git a/general/datasets/UCLA_CXB_Aor_Jan16/summary.rtf b/general/datasets/UCLA_CXB_Aor_Jan16/summary.rtf new file mode 100644 index 0000000..59e49a1 --- /dev/null +++ b/general/datasets/UCLA_CXB_Aor_Jan16/summary.rtf @@ -0,0 +1 @@ +Identify genes in the aorta whose expression is under genetic regulation in the Hybrid Mouse Diversity Panel (HMDP). The HMDP comprises classical inbred and recombinant inbred wild type mice. 104 of these strains were bred onto a C57BL/6J background carrying transgenes for both ApoE-Leiden and cholesteryl ester transfer protein (CETP). The RMA values of genes were used for genome wide association as described in Davis et al PLOS Genetics 2015. These data are used to identify candidate genes at loci associated with atherosclerotic lesion size.
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