From b2feda451ccfbeaed02dce9088d6dd228cf15861 Mon Sep 17 00:00:00 2001 From: Bonface Date: Tue, 13 Feb 2024 23:52:26 -0600 Subject: Update dataset RTF Files. --- general/datasets/Het3_itppublish/citation.rtf | 18 ++++++++++++++++++ general/datasets/Het3_itppublish/specifics.rtf | 1 + general/datasets/Het3_itppublish/summary.rtf | 5 +++++ 3 files changed, 24 insertions(+) create mode 100644 general/datasets/Het3_itppublish/citation.rtf create mode 100644 general/datasets/Het3_itppublish/specifics.rtf create mode 100644 general/datasets/Het3_itppublish/summary.rtf (limited to 'general/datasets/Het3_itppublish') diff --git a/general/datasets/Het3_itppublish/citation.rtf b/general/datasets/Het3_itppublish/citation.rtf new file mode 100644 index 0000000..e723d03 --- /dev/null +++ b/general/datasets/Het3_itppublish/citation.rtf @@ -0,0 +1,18 @@ +

The first use of this strain designation was UM-HET3

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Miller, R. A., C. Chrisp, and A. Galecki. 1997. CD4 memory T cell levels predict lifespan in genetically heterogeneous mice. FASEB Journal 11:775-783

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UM-HET3 mice are neither an F1 nor an F2 hybrid. (An F2 hybrid is made by crossing males and females of the same F1 hybrid stock.) The correct designation is a "four-way cross."

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Publications from the NIA Interventions Testing Program

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The first ITP paper also referred to these mice as UM-HET3, using this strain designation regardless of the site at which the mice were produced.  +See: 

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Miller, R. A., D. E. Harrison, C. M. Astle, R. A. Floyd, K. Flurkey, K. L. Hensley, M. A. Javors, C. Leeuwenburgh, J. F. Nelson, E. Ongini, N. L. Nadon, H. R. Warner, R. Strong. 2007. An aging interventions testing program: study design and interim report. Aging Cell 6: 565 - 575. [PMC: 17578509]

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ITP1: Interventions Testing Program: Effects of various treatments on lifespan and related phenotypes in genetically heterogeneous mice (UM-HET3) (2004-2022)

diff --git a/general/datasets/Het3_itppublish/specifics.rtf b/general/datasets/Het3_itppublish/specifics.rtf new file mode 100644 index 0000000..4c7f4e9 --- /dev/null +++ b/general/datasets/Het3_itppublish/specifics.rtf @@ -0,0 +1 @@ +Aging Mouse Lifespan Studies (NIA UM-HET3) \ No newline at end of file diff --git a/general/datasets/Het3_itppublish/summary.rtf b/general/datasets/Het3_itppublish/summary.rtf new file mode 100644 index 0000000..4a3de8b --- /dev/null +++ b/general/datasets/Het3_itppublish/summary.rtf @@ -0,0 +1,5 @@ +

http://www-personal.umich.edu/~millerr/ITP.htm

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https://www.nia.nih.gov/research/dab/interventions-testing-program-itp/frequently-asked-questions-about-itp

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https://www.nia.nih.gov/research/dab/interventions-testing-program-itp/compounds-testing

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