From d029d5d7f8ead1f1de8d318045004a4a6f68f5fb Mon Sep 17 00:00:00 2001 From: Bonface Date: Fri, 9 Feb 2024 09:41:28 -0600 Subject: Update dataset RTF Files. --- general/datasets/EPFL_LISPBXDHeCDEx0114/summary.rtf | 1 + 1 file changed, 1 insertion(+) create mode 100644 general/datasets/EPFL_LISPBXDHeCDEx0114/summary.rtf (limited to 'general/datasets/EPFL_LISPBXDHeCDEx0114/summary.rtf') diff --git a/general/datasets/EPFL_LISPBXDHeCDEx0114/summary.rtf b/general/datasets/EPFL_LISPBXDHeCDEx0114/summary.rtf new file mode 100644 index 0000000..7fcc1a9 --- /dev/null +++ b/general/datasets/EPFL_LISPBXDHeCDEx0114/summary.rtf @@ -0,0 +1 @@ +

The BXD genetic reference population is a recombinant inbred panel descended from crosses between the C57BL/6 (B6) and DBA/2 (D2) strains of mice, which segregate for about 5 million sequence variants. Recently, some these variants have been established with effects on general metabolic phenotypes such as glucose response and bone strength. In this study, we examined both genetic variants across 40 strains of BXD and the two founder lines, in addition to a major environmental influence—long term feeding with chow diet (CD) or high fat diet (HFD)—to see how metabolic gene expression varies by genotype and environment, and gene-by-environment interactions. The basic heart phenotypes quantified in these cohorts were not affected by HFD feeding (e.g. blood pressure and heart rate). 

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