From e34e7da50fc0ff5ed41e8bdaf2b1d41c9e9cf534 Mon Sep 17 00:00:00 2001 From: Bonface Date: Thu, 15 Feb 2024 06:09:54 -0600 Subject: Update dataset RTF Files. --- general/datasets/EPFLBXDprotHFDRPN0513/cases.rtf | 1 - 1 file changed, 1 deletion(-) delete mode 100644 general/datasets/EPFLBXDprotHFDRPN0513/cases.rtf (limited to 'general/datasets/EPFLBXDprotHFDRPN0513/cases.rtf') diff --git a/general/datasets/EPFLBXDprotHFDRPN0513/cases.rtf b/general/datasets/EPFLBXDprotHFDRPN0513/cases.rtf deleted file mode 100644 index ed4ced8..0000000 --- a/general/datasets/EPFLBXDprotHFDRPN0513/cases.rtf +++ /dev/null @@ -1 +0,0 @@ -

40 strains of the BXD family (BXD43 – BXD103) and both parental strains (C57BL/6 and DBA/2) were born and raised at the EPFL in Switzerland prior to inclusion in this study. For each strain, 10 male animals were born and then separated evenly into two cohorts at 8 weeks of age: 5 animals per strain on a chow diet (6% kcal/fat, 20% protein, 74% carbohydrate) and 5 animals per strain on high fat diet (60% kcal/fat, 20% protein, 20% carbohydrate). Animals adjusted to the diet for 8 weeks, and then an intensive phenotyping metabolic phenotyping protocol was followed from 16 to 24 weeks of age (respiration, cold tolerance, oral glucose response, VO2max exercise, voluntary exercise, basal activity). Animals were communally housed until the last 5 weeks of the experiment, when the animals could rest. Animals were fasted overnight prior to sacrifice, which occurred between 9am and 11am after isoflurane anesthesia and perfusion. The gall bladder was removed, and then the livers were immediately frozen in liquid nitrogen.

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