From d029d5d7f8ead1f1de8d318045004a4a6f68f5fb Mon Sep 17 00:00:00 2001 From: Bonface Date: Fri, 9 Feb 2024 09:41:28 -0600 Subject: Update dataset RTF Files. --- general/datasets/CCPublish/acknowledgment.rtf | 1 + general/datasets/CCPublish/cases.rtf | 3 +++ general/datasets/CCPublish/experiment-design.rtf | 1 + general/datasets/CCPublish/specifics.rtf | 1 + general/datasets/CCPublish/summary.rtf | 11 +++++++++++ general/datasets/CCPublish/tissue.rtf | 1 + 6 files changed, 18 insertions(+) create mode 100644 general/datasets/CCPublish/acknowledgment.rtf create mode 100644 general/datasets/CCPublish/cases.rtf create mode 100644 general/datasets/CCPublish/experiment-design.rtf create mode 100644 general/datasets/CCPublish/specifics.rtf create mode 100644 general/datasets/CCPublish/summary.rtf create mode 100644 general/datasets/CCPublish/tissue.rtf (limited to 'general/datasets/CCPublish') diff --git a/general/datasets/CCPublish/acknowledgment.rtf b/general/datasets/CCPublish/acknowledgment.rtf new file mode 100644 index 0000000..c6129ca --- /dev/null +++ b/general/datasets/CCPublish/acknowledgment.rtf @@ -0,0 +1 @@ +

LS and MB would like to thank the Luxembourg National Research Fund (FNR) for the support 663 (FNR CORE C15/BM/10406131 grant).

diff --git a/general/datasets/CCPublish/cases.rtf b/general/datasets/CCPublish/cases.rtf new file mode 100644 index 0000000..4a36b15 --- /dev/null +++ b/general/datasets/CCPublish/cases.rtf @@ -0,0 +1,3 @@ +

CC mice were bred by Dr. Klaus Schughart at the HZI, Braunschweig, Germany.

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C57BL/6J, A/J, and DBA/2J were bred by University of Luxembourg

diff --git a/general/datasets/CCPublish/experiment-design.rtf b/general/datasets/CCPublish/experiment-design.rtf new file mode 100644 index 0000000..e0fbda8 --- /dev/null +++ b/general/datasets/CCPublish/experiment-design.rtf @@ -0,0 +1 @@ +

Gas chromatography-mass spectrometry (GC-MS), immunofluorescent staining, RT-PCR

diff --git a/general/datasets/CCPublish/specifics.rtf b/general/datasets/CCPublish/specifics.rtf new file mode 100644 index 0000000..fc3ed76 --- /dev/null +++ b/general/datasets/CCPublish/specifics.rtf @@ -0,0 +1 @@ +CC Phenotypes \ No newline at end of file diff --git a/general/datasets/CCPublish/summary.rtf b/general/datasets/CCPublish/summary.rtf new file mode 100644 index 0000000..d4904aa --- /dev/null +++ b/general/datasets/CCPublish/summary.rtf @@ -0,0 +1,11 @@ +

Dopamine concentration measurements [pmol/mg]: Dorsal striatums of 32 CC strains. Each strain has around 5 male and 5 female animals, 3-month old; Dorsal striatums

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Neuropathology: The dorsal striatum was sectioned and stained with TH or DAT. Two metrics were measured: mean grey value [mean grey value/image] and % area occupied [% area occupied/image]. Measurements were done on dorsal striatums of C57BL/6J, A/J and DBA/2J 3, 9, 15-month-old animals.

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RT-PCR: The total RNA was extracted from ventral midbrains and quantified by RT-PCR with markers Th, Dat, Vmat, Nr4a2, Sox6 and Otx2 [-delta Ct]. Measurements were done on dorsal striatums of C57BL/6J, A/J and DBA/2J 3, 9, 15-month-old animals.

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Team of Investigators:

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Lasse Sinkkkonen, Manuel Buttini, Yujuan Gui, and Melanie Thomas at the University of Luxembourg

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Data entered into GeneNetwork December 2019 by Arthur Centeno, Robert W. Williams, Yujuan Gui.

diff --git a/general/datasets/CCPublish/tissue.rtf b/general/datasets/CCPublish/tissue.rtf new file mode 100644 index 0000000..9869ae6 --- /dev/null +++ b/general/datasets/CCPublish/tissue.rtf @@ -0,0 +1 @@ +

Dorsal Striatum, ventral midbrain

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