"""This contains all the necessary functions that are required to add traits to the published database""" from dataclasses import dataclass from typing import Any, Dict, Optional @dataclass(frozen=True) class Riset: """Class for keeping track of riset. A riset is a group e.g. rat HSNIH-Palmer, BXD """ name: Optional[str] r_id: Optional[int] @dataclass(frozen=True) class WebqtlCaseData: """Class for keeping track of one case data in one trait""" value: Optional[float] = None variance: Optional[float] = None count: Optional[int] = None # Number of Individuals def __str__(self): _str = "" if self.value: _str += f"value={self.value:.3f}" if self.variance: _str += f" variance={self.variance:.3f}" if self.count: _str += " n_data={self.count}" return _str def lookup_webqtldataset_name(riset_name: str, conn: Any): """Given a group name(riset), return it's name e.g. BXDPublish, HLCPublish.""" with conn.cursor() as cursor: cursor.execute( "SELECT PublishFreeze.Name FROM " "PublishFreeze, InbredSet WHERE " "PublishFreeze.InbredSetId = InbredSet.Id " "AND InbredSet.Name = '%s'" % riset_name) _result, *_ = cursor.fetchone() return _result def get_riset(data_type: str, name: str, conn: Any): """Get the groups given the data type and it's PublishFreeze or GenoFreeze name """ query, _name, _id = None, None, None if data_type == "Publish": query = ("SELECT InbredSet.Name, InbredSet.Id FROM InbredSet, " "PublishFreeze WHERE PublishFreeze.InbredSetId = " "InbredSet.Id AND PublishFreeze.Name = '%s'" % name) elif data_type == "Geno": query = ("SELECT InbredSet.Name, InbredSet.Id FROM InbredSet, " "GenoFreeze WHERE GenoFreeze.InbredSetId = " "InbredSet.Id AND GenoFreeze.Name = '%s'" % name) elif data_type == "ProbeSet": query = ("SELECT InbredSet.Name, InbredSet.Id FROM " "InbredSet, ProbeSetFreeze, ProbeFreeze WHERE " "ProbeFreeze.InbredSetId = InbredSet.Id AND " "ProbeFreeze.Id = ProbeSetFreeze.ProbeFreezeId AND " "ProbeSetFreeze.Name = '%s'" % name) if query: with conn.cursor() as cursor: _name, _id = cursor.fetchone() if _name == "BXD300": _name = "BXD" return Riset(_name, _id) def insert_publication(pubmed_id: int, publication: Optional[Dict], conn: Any): """Creates a new publication record if it's not available""" sql = ("SELECT Id FROM Publication where " "PubMed_ID = %d" % pubmed_id) _id = None with conn.cursor() as cursor: cursor.execute(sql) _id = cursor.fetchone() if not _id and publication: # The Publication contains the fields: 'authors', 'title', 'abstract', # 'journal','volume','pages','month','year' insert_query = ("INSERT into Publication (%s) Values (%s)" % (", ".join(publication.keys()), ", ".join(['%s'] * len(publication)))) with conn.cursor() as cursor: cursor.execute(insert_query, tuple(publication.values())) def retrieve_probeset_trait_name(threshold, name, connection): """ Retrieve the name for a Probeset trait This is extracted from the `webqtlDataset.retrieveName` function, specifically the section dealing with 'ProbeSet' type traits https://github.com/genenetwork/genenetwork1/blob/master/web/webqtl/base/webqtlDataset.py#L140-154""" query = ( 'SELECT Id, Name, FullName, ShortName, DataScale ' 'FROM ProbeSetFreeze ' 'WHERE ' 'public > %(threshold)s ' 'AND ' '(Name = %(name)s OR FullName = %(name)s OR ShortName = %(name)s)') with connection.cursor() as cursor: cursor.execute(query, {"threshold": threshold, "name": name}) return cursor.fetchone()