"""API for fetching metadata using an API""" from string import Template from http.client import RemoteDisconnected from urllib.error import URLError from flask import Blueprint from flask import jsonify from flask import request from flask import current_app from gn3.db.rdf import RDF_PREFIXES from gn3.db.rdf import (query_frame_and_compact, query_and_compact, query_and_frame) BASE_CONTEXT = { "data": "@graph", "id": "@id", "type": "@type", "gnc": "http://genenetwork.org/category/", "gnt": "http://genenetwork.org/term/", "rdfs": "http://www.w3.org/2000/01/rdf-schema#", "rdf": "http://www.w3.org/1999/02/22-rdf-syntax-ns#>", } DATASET_CONTEXT = { "accessRights": "dct:accessRights", "accessionId": "dct:identifier", "acknowledgement": "gnt:hasAcknowledgement", "altLabel": "skos:altLabel", "caseInfo": "gnt:hasCaseInfo", "classifiedUnder": "xkos:classifiedUnder", "contributors": "dct:creator", "contactPoint": "dcat:contactPoint", "created": "dct:created", "dcat": "http://www.w3.org/ns/dcat#", "dct": "http://purl.org/dc/terms/", "description": "dct:description", "ex": "http://example.org/stuff/1.0/", "experimentDesignInfo": "gnt:hasExperimentDesignInfo", "foaf": "http://xmlns.com/foaf/0.1/", "geoSeriesId": "gnt:hasGeoSeriesId", "gnt": "http://genenetwork.org/term/", "inbredSet": "gnt:belongsToGroup", "label": "rdfs:label", "normalization": "gnt:usesNormalization", "platformInfo": "gnt:hasPlatformInfo", "notes": "gnt:hasNotes", "organization": "foaf:Organization", "prefLabel": "skos:prefLabel", "citation": "dct:isReferencedBy", "GoTree": "gnt:hasGOTreeValue", "platform": "gnt:usesPlatform", "processingInfo": "gnt:hasDataProcessingInfo", "rdfs": "http://www.w3.org/2000/01/rdf-schema#", "skos": "http://www.w3.org/2004/02/skos/core#", "specifics": "gnt:hasContentInfo", "title": "dct:title", "xkos": "http://rdf-vocabulary.ddialliance.org/xkos#", "tissueInfo": "gnt:hasTissueInfo", "tissue": "gnt:hasTissue", "contactWebUrl": "foaf:homepage", "contactName": "foaf:name", } SEARCH_CONTEXT = { "pages": "ex:pages", "hits": "ex:hits", "result": "ex:result", "results": "ex:items", "resultItem": "ex:resultType", "currentPage": "ex:currentPage", } DATASET_SEARCH_CONTEXT = SEARCH_CONTEXT | { "classifiedUnder": "xkos:classifiedUnder", "created": "dct:created", "dct": "http://purl.org/dc/terms/", "ex": "http://example.org/stuff/1.0/", "inbredSet": "ex:belongsToInbredSet", "title": "dct:title", "name": "rdfs:label", "rdfs": "http://www.w3.org/2000/01/rdf-schema#", "type": "@type", "xkos": "http://rdf-vocabulary.ddialliance.org/xkos#", } PUBLICATION_CONTEXT = { "dct": "http://purl.org/dc/terms/", "fabio": "http://purl.org/spar/fabio/", "prism": "http://prismstandard.org/namespaces/basic/2.0/", "xsd": "http://www.w3.org/2001/XMLSchema#", "title": "dct:title", "journal": "fabio:Journal", "volume": "prism:volume", "page": "fabio:page", "creator": "dct:creator", "abstract": "dct:abstract", "year": { "@id": "fabio:hasPublicationYear", "@type": "xsd:gYear", }, "month": { "@id": "prism:publicationDate", "@type": "xsd:gMonth" }, } PHENOTYPE_CONTEXT = BASE_CONTEXT | PUBLICATION_CONTEXT | { "skos": "http://www.w3.org/2004/02/skos/core#", "dcat": "http://www.w3.org/ns/dcat#", "prism": "http://prismstandard.org/namespaces/basic/2.0/", "traitName": "skos:altLabel", "trait": "rdfs:label", "altName": "rdfs:altLabel", "description": "dct:description", "abbreviation": "gnt:abbreviation", "labCode": "gnt:labCode", "submitter": "gnt:submitter", "dataset": "dcat:Distribution", "contributor": "dct:contributor", "mean": "gnt:mean", "locus": "gnt:locus", "lodScore": "gnt:lodScore", "references": "dct:isReferencedBy", "additive": "gnt:additive", "sequence": "gnt:sequence", "prefLabel": "skos:prefLabel", "identifier": "dct:identifier", "chromosome": "gnt:chr", "mb": "gnt:mb", "peakLocation": "gnt:locus", "species": "gnt:belongsToSpecies", "group": "gnt:belongsToGroup", } metadata = Blueprint("metadata", __name__) @metadata.route("/datasets/", methods=["GET"]) def datasets(name): """Fetch a dataset's metadata given it's ACCESSION_ID or NAME""" try: _query = Template(""" $prefix CONSTRUCT { ?dataset ?predicate ?term ; gnt:usesNormalization ?normalization . ?inbredSet rdfs:label ?inbredSetName . ?platform ?platformPred ?platformObject ; gnt:hasPlatformInfo ?platformInfo . ?normalization rdfs:label ?normalizationName . ?tissue ?tissuePred ?tissueObj ; gnt:hasTissueInfo ?tissueInfo . ?investigator foaf:name ?investigatorName ; foaf:homepage ?homepage . ?type skos:prefLabel ?altName . } WHERE { ?dataset rdf:type dcat:Dataset ; ?predicate ?term ; (rdfs:label|dct:identifier|skos:prefLabel) "$name" . FILTER (!regex(str(?predicate), '(hasTissueInfo)', 'i')) . FILTER (!regex(str(?predicate), '(usesNormalization)', 'i')) . FILTER (!regex(str(?predicate), '(platformInfo)', 'i')) . OPTIONAL { ?dataset gnt:hasPlatformInfo ?platformInfo . } . OPTIONAL { ?inbredSet ^skos:member gnc:Set ; ^gnt:belongsToGroup ?dataset ; rdfs:label ?inbredSetName . } . OPTIONAL { ?type ^xkos:classifiedUnder ?dataset ; ^skos:member gnc:DatasetType ; skos:prefLabel ?altName . } . OPTIONAL { ?investigator foaf:name ?investigatorName ; foaf:homepage ?homepage ; ^dcat:contactPoint ?dataset . } . OPTIONAL { ?platform ^gnt:usesPlatform ?dataset ; ?platformPred ?platformObject . } . OPTIONAL { ?dataset gnt:usesNormalization ?normalization . ?normalization rdf:type gnc:avgMethod ; rdfs:label ?normalizationName . } . OPTIONAL { ?dataset gnt:hasPlatformInfo ?platformInfo . } . OPTIONAL { ?dataset gnt:hasTissueInfo ?tissueInfo . } . OPTIONAL { ?dataset gnt:hasTissue ?tissue . ?tissue rdfs:label ?tissueName ; ?tissuePred ?tissueObj . } . }""").substitute(prefix=RDF_PREFIXES, name=name) _context = { "@context": BASE_CONTEXT | DATASET_CONTEXT, "type": "dcat:Dataset", } return query_frame_and_compact( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/datasets//list", methods=["GET"]) def list_datasets_by_group(group): """List datasets that belong to a given group""" try: args = request.args page = args.get("page", 0) page_size = args.get("per-page", 10) _query = Template(""" $prefix CONSTRUCT { ex:result rdf:type ex:resultType ; ex:totalCount ?totalCount ; ex:currentPage $offset ; ex:items [ rdfs:label ?datasetName ; dct:identifier ?accessionId ; dct:created ?createTime ; dct:title ?title ; ] . } WHERE { { SELECT ?datasetName ?accessionId ?createTime ?title WHERE { ?dataset rdf:type dcat:Dataset ; rdfs:label ?datasetName . ?inbredSet ^skos:member gnc:Set ; ^xkos:classifiedUnder ?dataset ; rdfs:label ?inbredSetName ; skos:prefLabel ?group . ?group bif:contains "$group" . OPTIONAL { ?dataset dct:identifier ?accesionId . } . OPTIONAL { ?dataset dct:created ?createTime . } . OPTIONAL { ?dataset dct:title ?title . } . } ORDER BY ?createTime LIMIT $limit OFFSET $offset } { SELECT (COUNT(DISTINCT ?dataset)/$limit+1 AS ?totalCount) WHERE { ?dataset rdf:type dcat:Dataset ; rdfs:label ?datasetName . ?inbredSet ^skos:member gnc:Set ; ^xkos:classifiedUnder ?dataset ; rdfs:label ?inbredSetName ; skos:prefLabel ?group . ?group bif:contains "$group" . } } } """).substitute(prefix=RDF_PREFIXES, group=group, limit=page_size, offset=page) _context = { "@context": BASE_CONTEXT | DATASET_SEARCH_CONTEXT, "type": "resultItem", } return query_frame_and_compact( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/datasets/search/", methods=["GET"]) def search_datasets(term): """Search datasets""" try: args = request.args page = args.get("page", 0) page_size = args.get("per-page", 10) _query = Template(""" $prefix CONSTRUCT { ex:result rdf:type ex:resultType ; ex:pages ?pages ; ex:hits ?hits ; ex:currentPage $offset ; ex:items [ rdfs:label ?label ; dct:title ?title ; ex:belongsToInbredSet ?inbredSetName ; xkos:classifiedUnder ?datasetType ; ] } WHERE { { SELECT DISTINCT ?dataset ?label ?inbredSetName ?datasetType ?title WHERE { ?dataset rdf:type dcat:Dataset ; rdfs:label ?label ; ?datasetPredicate ?datasetObject ; xkos:classifiedUnder ?inbredSet . ?inbredSet ^skos:member gnc:Set ; rdfs:label ?inbredSetName . ?datasetObject bif:contains "'$term'" . OPTIONAL { ?dataset dct:title ?title . } . OPTIONAL { ?classification ^xkos:classifiedUnder ?dataset ; ^skos:member gnc:DatasetType ; ?typePredicate ?typeName ; skos:prefLabel ?datasetType . } } ORDER BY ?dataset LIMIT $limit OFFSET $offset } { SELECT (COUNT(DISTINCT ?dataset)/$limit+1 AS ?pages) (COUNT(DISTINCT ?dataset) AS ?hits) WHERE { ?dataset rdf:type dcat:Dataset ; ?p ?o . ?o bif:contains "'$term'" . } } } """).substitute(prefix=RDF_PREFIXES, term=term, limit=page_size, offset=page) _context = { "@context": BASE_CONTEXT | DATASET_SEARCH_CONTEXT, "type": "resultItem", } return query_frame_and_compact( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/publications/", methods=["GET"]) def publications(name): """Fetch a publication's metadata given it's NAME""" try: if "unpublished" in name: name = f"gn:unpublished{name}" else: name = f"pubmed:{name}" _query = Template(""" $prefix CONSTRUCT { $name ?predicate ?object . } WHERE { $name rdf:type fabio:ResearchPaper ; ?predicate ?object . FILTER (!regex(str(?predicate), '(hasPubMedId)', 'i')) . } """).substitute(name=name, prefix=RDF_PREFIXES) return query_and_compact( _query, {"@context": BASE_CONTEXT | PUBLICATION_CONTEXT}, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/publications/search/", methods=["GET"]) def search_publications(term): """Search publications""" try: args = request.args page = args.get("page", 0) page_size = args.get("per-page", 10) _query = Template(""" $prefix CONSTRUCT { ex:result rdf:type ex:resultType ; ex:totalCount ?totalCount ; ex:currentPage $offset ; ex:items [ rdfs:label ?publication ; dct:title ?title ; ] } WHERE { { SELECT ?publication ?title ?pmid WHERE { ?pub rdf:type fabio:ResearchPaper ; ?predicate ?object ; dct:title ?title . ?object bif:contains "'$term'" . BIND( STR(?pub) AS ?publication ) . } ORDER BY ?title LIMIT $limit OFFSET $offset } { SELECT (COUNT(*)/$limit+1 AS ?totalCount) WHERE { ?publication rdf:type fabio:ResearchPaper ; ?predicate ?object . ?object bif:contains "'$term'" . } } } """).substitute(prefix=RDF_PREFIXES, term=term, limit=page_size, offset=page) _context = { "@context": BASE_CONTEXT | SEARCH_CONTEXT | { "dct": "http://purl.org/dc/terms/", "ex": "http://example.org/stuff/1.0/", "rdfs": "http://www.w3.org/2000/01/rdf-schema#", "fabio": "http://purl.org/spar/fabio/", "title": "dct:title", "pubmed": "fabio:hasPubMedId", "currentPage": "ex:currentPage", "url": "rdfs:label", }, "type": "resultItem", "paper": { "@type": "fabio:ResearchPaper", "@container": "@index" } } return query_and_frame( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/phenotypes/",methods=["GET"]) @metadata.route("/phenotypes//", methods=["GET"]) def phenotypes(name, group=None): """Fetch a phenotype's metadata given it's name""" try: if group: name = f"{group}_{name}" _query = Template(""" $prefix CONSTRUCT { ?phenotype ?predicate ?object ; gnt:belongsToSpecies ?speciesName ; dcat:Distribution ?dataset ; gnt:belongsToGroup ?inbredSetName ; gnt:locus ?geno . ?dataset skos:prefLabel ?datasetName ; dct:identifier ?datasetLabel ; rdf:type dcat:Dataset . ?publication ?pubPredicate ?pubObject . ?geno rdfs:label ?locus ; gnt:chr ?chr ; gnt:mb ?mb . } WHERE { ?phenotype skos:altLabel "$name" ; gnt:belongsToGroup ?inbredSet ; ?predicate ?object . ?inbredSet rdfs:label ?inbredSetName ; xkos:generalizes ?species . ?species skos:prefLabel ?speciesName . OPTIONAL { ?publication ^dct:isReferencedBy ?phenotype ; rdf:type fabio:ResearchPaper ; ?pubPredicate ?pubObject . FILTER (!regex(str(?pubPredicate), '(hasPubMedId|type)', 'i')) . } . OPTIONAL { ?geno ^gnt:locus ?phenotype ; rdf:type gnc:Genotype ; rdfs:label ?locus ; gnt:chr ?chr ; gnt:mb ?mb . } . OPTIONAL { ?dataset rdf:type dcat:Dataset ; gnt:belongsToGroup ?inbredSet ; xkos:classifiedUnder gnc:Phenotype ; rdfs:label ?datasetLabel ; skos:prefLabel ?datasetName . ?type ^skos:member gnc:DatasetType . FILTER(?type = gnc:Phenotype) . } } """).substitute(prefix=RDF_PREFIXES, name=name) _context = { "@context": PHENOTYPE_CONTEXT, "dataset": { "type": "dcat:Dataset", }, "type": "gnc:Phenotype", } return query_frame_and_compact( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/genotypes/", methods=["GET"]) def genotypes(name): """Fetch a genotype's metadata given it's name""" try: _query = Template(""" $prefix CONSTRUCT { ?genotype ?predicate ?object . ?species rdfs:label ?speciesName . } WHERE { ?genotype rdf:type gnc:Genotype ; rdfs:label "$name" ; ?predicate ?object . OPTIONAL { ?species ^xkos:classifiedUnder ?genotype ; rdfs:label ?speciesName . } } """).substitute(prefix=RDF_PREFIXES, name=name) _context = { "@context": BASE_CONTEXT | { "rdfs": "http://www.w3.org/2000/01/rdf-schema#", "gnt": "http://genenetwork.org/term/", "xkos": "http://rdf-vocabulary.ddialliance.org/xkos#", "gnc": "http://genenetwork.org/category/", "xsd": "http://www.w3.org/2001/XMLSchema#", "name": "rdfs:label", "chr": "gnt:chr", "mb": "gnt:mb", "mbMm8": "gnt:mbMm8", "mb2016": "gnt:mb2016", "sequence": "gnt:hasSequence", "source": "gnt:hasSource", "species": "xkos:classifiedUnder", "alternateSource": "gnt:hasAltSourceName", "comments": "rdfs:comments", "chrNum": { "@id": "gnt:chrNum", "@type": "xsd:int", } }, "type": "gnc:Genotype", } return query_frame_and_compact( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/genewikis/gn/", methods=["GET"]) def get_gn_genewiki_entries(symbol): """Fetch the GN and NCBI GeneRIF entries""" try: args = request.args page = args.get("page", 0) page_size = args.get("per-page", 10) _query = Template(""" $prefix CONSTRUCT { ?symbol ex:entries [ rdfs:comment ?comment ; ex:species ?species_ ; dct:created ?createTime ; dct:references ?pmids ; dct:creator ?creator ; gnt:belongsToCategory ?categories ; ] . ?symbol rdf:type gnc:GNWikiEntry ; ex:totalCount ?totalCount ; ex:currentPage $offset . } WHERE { { SELECT ?symbol ?comment (GROUP_CONCAT(DISTINCT ?speciesName; SEPARATOR='; ') AS ?species_) ?createTime ?creator (GROUP_CONCAT(DISTINCT ?pubmed; SEPARATOR='; ') AS ?pmids) (GROUP_CONCAT(DISTINCT ?category; SEPARATOR='; ') AS ?categories) WHERE { ?symbol rdfs:label ?label ; rdfs:comment _:entry . ?label bif:contains "'$symbol'" . _:entry rdf:type gnc:GNWikiEntry ; rdfs:comment ?comment . OPTIONAL { ?species ^xkos:classifiedUnder _:entry ; ^skos:member gnc:Species ; skos:prefLabel ?speciesName . } . OPTIONAL { _:entry dct:created ?createTime . } . OPTIONAL { _:entry dct:references ?pubmed . } . OPTIONAL { ?investigator foaf:name ?creator ; ^dct:creator _:entry . } . OPTIONAL { _:entry gnt:belongsToCategory ?category . } . } GROUP BY ?comment ?symbol ?createTime ?creator ORDER BY ?createTime LIMIT $limit OFFSET $offset } { SELECT (COUNT(DISTINCT ?comment)/$limit+1 AS ?totalCount) WHERE { ?symbol rdfs:comment _:entry ; rdfs:label ?label . _:entry rdfs:comment ?comment ; rdf:type gnc:GNWikiEntry . ?label bif:contains "'$symbol'" . } } } """).substitute(prefix=RDF_PREFIXES, symbol=symbol, limit=page_size, offset=page) _context = { "@context": BASE_CONTEXT | { "ex": "http://example.org/stuff/1.0/", "rdfs": "http://www.w3.org/2000/01/rdf-schema#", "gnt": "http://genenetwork.org/term/", "gnc": "http://genenetwork.org/category/", "dct": "http://purl.org/dc/terms/", "xsd": "http://www.w3.org/2001/XMLSchema#", "entries": "ex:entries", "comment": "rdfs:comment", "species": "ex:species", "category": 'gnt:belongsToCategory', "author": "dct:creator", "pubmed": "dct:references", "currentPage": "ex:currentPage", "pages": "ex:totalCount", "created": { "@id": "dct:created", "@type": "xsd:datetime" }, }, "type": "gnc:GNWikiEntry" } return query_frame_and_compact( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/genewikis/ncbi/", methods=["GET"]) def get_ncbi_genewiki_entries(symbol): """Fetch the NCBI GeneRIF entries""" try: args = request.args page, page_size = args.get("page", 0), args.get("per-page", 10) _query = Template(""" $prefix CONSTRUCT { ?symbol ex:entries [ rdfs:comment ?comment ; gnt:hasGeneId ?geneId ; ex:species ?species_ ; dct:created ?createTime ; dct:references ?pmids ; dct:creator ?creator ; ] . ?symbol rdf:type gnc:GNWikiEntry ; ex:totalCount ?totalCount ; ex:currentPage $offset . } WHERE { { SELECT ?symbol ?comment ?geneId (GROUP_CONCAT(DISTINCT ?speciesName; SEPARATOR='; ') AS ?species_) ?createTime ?creator (GROUP_CONCAT(DISTINCT ?pubmed; SEPARATOR='; ') AS ?pmids) WHERE { ?symbol rdfs:label ?label ; rdfs:comment _:entry . ?label bif:contains "'$symbol'" . _:entry rdf:type gnc:NCBIWikiEntry ; rdfs:comment ?comment . OPTIONAL { ?species ^xkos:classifiedUnder _:entry ; ^skos:member gnc:Species ; skos:prefLabel ?speciesName . } . OPTIONAL { _:entry gnt:hasGeneId ?geneId . } . OPTIONAL { _:entry dct:created ?createTime . } . OPTIONAL { _:entry dct:references ?pubmed . } . OPTIONAL { ?investigator foaf:name ?creator ; ^dct:creator _:entry . } . } GROUP BY ?comment ?symbol ?createTime ?creator ?geneId ORDER BY ?createTime LIMIT $limit OFFSET $offset } { SELECT (COUNT(DISTINCT ?comment)/$limit+1 AS ?totalCount) WHERE { ?symbol rdfs:comment _:entry ; rdfs:label ?label . _:entry rdfs:comment ?comment ; rdf:type gnc:NCBIWikiEntry . ?label bif:contains "'$symbol'" . } } } """).substitute(prefix=RDF_PREFIXES, symbol=symbol, limit=page_size, offset=page) _context = { "@context": BASE_CONTEXT | { "ex": "http://example.org/stuff/1.0/", "rdfs": "http://www.w3.org/2000/01/rdf-schema#", "gnt": "http://genenetwork.org/term/", "gnc": "http://genenetwork.org/category/", "dct": "http://purl.org/dc/terms/", "xsd": "http://www.w3.org/2001/XMLSchema#", "entries": "ex:entries", "comment": "rdfs:comment", "category": 'gnt:belongsToCategory', "author": "dct:creator", "species": "ex:species", "geneId": "gnt:hasGeneId", "pubmed": "dct:references", "currentPage": "ex:currentPage", "pages": "ex:totalCount", "created": { "@id": "dct:created", "@type": "xsd:datetime" }, }, "type": "gnc:GNWikiEntry" } return query_frame_and_compact( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/species", methods=["GET"]) def list_species(): """List all species""" try: _query = Template(""" $prefix CONSTRUCT { ?species ?predicate ?object . } WHERE { ?species ^skos:member gnc:Species ; ?predicate ?object . VALUES ?predicate { rdfs:label skos:prefLabel skos:altLabel gnt:shortName gnt:family skos:notation } } """).substitute(prefix=RDF_PREFIXES) _context = { "@context": BASE_CONTEXT | { "skos": "http://www.w3.org/2004/02/skos/core#", "gnt": "http://genenetwork.org/term/", "rdfs": "http://www.w3.org/2000/01/rdf-schema#", "name": "rdfs:label", "family": "gnt:family", "shortName": "gnt:shortName", "alternateName": "skos:altLabel", "taxonomicId": "skos:notation", "fullName": "skos:prefLabel", }, } return query_and_compact( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/species/", methods=["GET"]) def fetch_species(name): """Fetch a Single species information""" try: _query = Template(""" $prefix CONSTRUCT { ?species ?predicate ?object . } WHERE { ?species ^skos:member gnc:Species ; gnt:shortName "$name" ; ?predicate ?object . VALUES ?predicate { rdfs:label skos:prefLabel skos:altLabel gnt:shortName gnt:family skos:notation } } """).substitute(prefix=RDF_PREFIXES, name=name) _context = { "@context": BASE_CONTEXT | { "skos": "http://www.w3.org/2004/02/skos/core#", "gnt": "http://genenetwork.org/term/", "rdfs": "http://www.w3.org/2000/01/rdf-schema#", "name": "rdfs:label", "family": "gnt:family", "shortName": "gnt:shortName", "alternateName": "skos:altLabel", "taxonomicId": "skos:notation", "fullName": "skos:prefLabel", }, } return query_and_compact( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/groups", methods=["GET"]) def groups(): """Fetch the list of groups""" try: _query = Template(""" $prefix CONSTRUCT { ?group ?predicate ?object . } WHERE { ?group ^skos:member gnc:Set ; ?predicate ?object . VALUES ?predicate { rdfs:label skos:prefLabel gnt:geneticType gnt:mappingMethod gnt:code gnt:family } } """).substitute(prefix=RDF_PREFIXES) _context = { "@context": BASE_CONTEXT | { "skos": "http://www.w3.org/2004/02/skos/core#", "gnt": "http://genenetwork.org/term/", "rdfs": "http://www.w3.org/2000/01/rdf-schema#", "name": "rdfs:label", "family": "gnt:family", "shortName": "gnt:shortName", "code": "gnt:code", "mappingMethod": "gnt:mappingMethod", "geneticType": "gnt:geneticType", "fullName": "skos:prefLabel", }, } return query_and_compact( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/groups/", methods=["GET"]) def fetch_group_by_species(name): """Fetch the list of groups (I.e. Inbredsets)""" try: _query = Template(""" $prefix CONSTRUCT { ?group ?predicate ?object . } WHERE { ?species gnt:shortName "$name" ; ^skos:member gnc:Species . ?group ^skos:member gnc:Set ; xkos:generalizes ?species ; ?predicate ?object . VALUES ?predicate { rdfs:label skos:prefLabel gnt:geneticType gnt:mappingMethod gnt:code gnt:family } } """).substitute(prefix=RDF_PREFIXES, name=name) _context = { "@context": BASE_CONTEXT | { "skos": "http://www.w3.org/2004/02/skos/core#", "gnt": "http://genenetwork.org/term/", "rdfs": "http://www.w3.org/2000/01/rdf-schema#", "name": "rdfs:label", "family": "gnt:family", "shortName": "gnt:shortName", "code": "gnt:code", "mappingMethod": "gnt:mappingMethod", "geneticType": "gnt:geneticType", "fullName": "skos:prefLabel", }, } return query_and_compact( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({}) @metadata.route("/probesets/", methods=["GET"]) def probesets(name): """Fetch a probeset's metadata given it's name""" try: _query = Template(""" $prefix CONSTRUCT { ?probeset ?predicate ?object ; dct:references ?probesetResource ; dct:references ?resource . ?resource rdfs:label ?resourceLabel ; rdfs:comments ?resourceComments . ?probesetResource rdfs:label ?probesetResourceLabel ; rdfs:comments ?probesetResourceComments . ?chip rdfs:label ?chipName . } WHERE { ?probeset rdf:type gnc:Probeset ; rdfs:label "$name" ; ?predicate ?object . FILTER (!regex(str(?genePred), '(geneSymbol)', 'i')) . OPTIONAL { ?probeset gnt:geneSymbol ?symbolName . ?gene gnt:geneSymbol ?symbolName ; rdf:type gnc:Gene . ?resource ^dct:references ?gene ; a ?resourceLink . ?resourceLink rdfs:Class gnc:ResourceLink ; rdfs:label ?resourceLabel ; rdfs:comments ?resourceComments . } . OPTIONAL { ?probeset gnt:hasChip ?chip . ?chip rdfs:label ?chipName . } . OPTIONAL { ?probesetResource ^dct:references ?probeset ; a ?probesetResourceLink . ?probesetResourceLink rdfs:label ?probesetResourceLabel ; rdfs:comments ?probesetResourceComments . } . } """).substitute(prefix=RDF_PREFIXES, name=name) _context = { "@context": BASE_CONTEXT | { "alias": "skos:altLabel", "alignID": "gnt:hasAlignID", "blatMbEnd": "gnt:hasBlatMbEnd", "blatMbStart": "gnt:hasBlatMbStart", "blatScore": "gnt:hasBlatScore", "blatSeq": "gnt:hasBlatSeq", "chip": "gnt:hasChip", "chr": "gnt:chr", "chromosome": "gnt:chromosome", "comments": "rdfs:comments", "dct": "http://purl.org/dc/terms/", "description": "dct:description", "geneID": "gnt:hasGeneId", "kgID": "gnt:hasKgID", "location": "gnt:location", "mb": "gnt:mb", "name": "rdfs:label", "proteinID": "gnt:hasProteinID", "references": "dct:references", "rgdID": "gnt:hasRgdID", "skos": "http://www.w3.org/2004/02/skos/core#", "species": "gnt:belongsToSpecies", "specificity": "gnt:hasSpecificity", "strand": "gnt:Strand", "strandProbe": "gnt:strandProbe", "symbol": "gnt:geneSymbol", "targetID": "gnt:hasTargetId", "targetRegion": "gnt:targetsRegion", "targetSequence": "gnt:hasTargetSeq", "transcript": "gnt:transcript", "txEnd": "gnt:TxEnd", "txStart": "gnt:TxStart", "unigenID": "gnt:hasUnigenID", "uniprot": "gnt:uniprot", }, "probeset": { "type": "gnc:Probeset", }, "type": "gnc:Probeset", } return query_frame_and_compact( _query, _context, current_app.config.get("SPARQL_ENDPOINT") ) except (RemoteDisconnected, URLError): return jsonify({})