aboutsummaryrefslogtreecommitdiff
path: root/gn3/db
diff options
context:
space:
mode:
Diffstat (limited to 'gn3/db')
-rw-r--r--gn3/db/genotypes.py37
1 files changed, 37 insertions, 0 deletions
diff --git a/gn3/db/genotypes.py b/gn3/db/genotypes.py
index be0dfc2..8710d2e 100644
--- a/gn3/db/genotypes.py
+++ b/gn3/db/genotypes.py
@@ -106,3 +106,40 @@ def parse_genotype_header(line: str, parlist = tuple()):
("mb_column", None if not Mbmap else items.index("Mb")),
("prgy", prgy),
("nprgy", len(prgy)))
+
+def parse_genotype_data_line(line: str, geno_obj: dict, parlist: list):
+ """
+ Parse a data line in a genotype file
+
+ DESCRIPTION:
+ Reworks
+ https://github.com/genenetwork/genenetwork1/blob/master/web/webqtl/utility/gen_geno_ob.py#L143-L190
+ """
+ marker_row = [item.strip() for item in line.split("\t")]
+ geno_table = {
+ geno_obj["mat"]: -1, geno_obj["pat"]: 1, geno_obj["het"]: 0,
+ geno_obj["unk"]: "U"
+ }
+ start_pos = 4 if geno_obj["Mbmap"] else 3
+ if len(parlist) > 0:
+ start_pos = start_pos + 2
+
+ alleles = marker_row[start_pos:]
+ genotype = tuple(
+ (geno_table[allele] if allele in geno_table.keys() else "U")
+ for allele in alleles)
+ if len(parlist) > 0:
+ genotype = (-1, 1) + genotype
+ try:
+ cM = float(geno_obj["cm_column"])
+ except:
+ if geno_obj["Mbmap"]:
+ cM = float(geno_obj["mb_column"])
+ else:
+ cM = 0
+ return (
+ ("chr", marker_row[0]),
+ ("name", marker_row[1]),
+ ("cM", cM),
+ ("Mb", float(geno_obj["mb_column"]) if geno_obj["Mbmap"] else None),
+ ("genotype", genotype))