Hars2 is not a well
characterized gene and their is no biology yet to support the hypothesis
that Hars2 modulates gene expression, let alone App expression in specific.
There are also serious database/assembly discrepancies between Celera and
MGSCv3 regarding the genomic organization of this gene. But there appear to
be approximately 69 SNPs in Hars2, one of which results in a substitution.