App has a suggestive QTL on Chr 2. What about the neighbors that we defined as having shared expression patterns. This figure shows that members of the immediate App neigborhood share a weak Chr 2 QTL.  That is what the blue oval in the background is meant to represent. But some transcripts, such as Ndr4 and Psen2 do not share this Chr 2 interval.

QUESTION: What kind of headway can we make in detemining what polymorphism or polymorphisms on Chr 2 near 130 Mb might contribute to the variance in the expression of all of these important transcripts?