UCLA BHHBF2 Muscle Female Only modify this page

Accession number: GN187

Data Status: Open data. Please cite: van Nas A, Ingram-Drake L, Sinsheimer JS, Wang SS, Schadt EE, Drake T, Lusis AJ (2010) Expression quantitative trait loci: replication, tissue- and sex-specificity in mice. Genetics 185:1059-1068 (PMID: 20439777

Summary:

This is a sex-specific subset of data published by van Nas and colleagues. They used an Agilent array to measure expression of most genes (~24,000 60-mer probes). The data are described more fully in the paper and in the GEO GSE data sets: Expression profiling of Muscle tissue from C57BL/6J X C3H/HeJ)F2 and (C3H/HeJ X C57BL/6J)F2

About the cases used to generate this set of data:

This is a sex-specific subset of the original data. Please see Gene Expression Omnibus data set GSE12795 for details.

About the tissue used to generate this set of data:

Muscle from F2 intercross progeny were generated by intercrossing F1 mice. Mice were fed chow diet containing 4% fat (Ralston-Purina Co., St. Louis, MO) until 8 weeks of age and then were placed on a high-fat "Western" diet containing 42% fat and 0.15% cholesterol (Teklad 88137, Harlan Teklad, Madison WI) for 12 weeks. At 20 weeks mice were sacrificed, after a 12-hour fast. Muscle tissues were dissected and flash frozen in liquid N2 and stored at -80 deg C.

IndexTubeIDGroupStrainAgeSexSource
1R2595E.1GDP129S1/SvImJ59FUTHSC RW

About downloading this data set:

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About the array platfrom:

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About data values and data processing:

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IndexTubeIDStrainOriginal CELScale factorBackground AveragePresentAbsentMarginalAFFX-b-ActinMur (3'/5')AFFX-GapdhMur (3'/5')Batch IdUsed for batch control
1R2595E.1129S1/SvImJR2595E.1.CEL1.7911561.00%37.50%1.50%1.460.771Y

Data source acknowledgment:

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Information about this text file:

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GEO Series Data: This section to be used for GEO submission of the whole series of arrays

GSE Series

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