<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN"> <HTML><HEAD><TITLE>OHSU HS-CC Striatum ILM6v1 (Feb11) RankInv</TITLE> <META http-equiv=Content-Type content="text/html; charset=iso-8859-1"> <LINK REL="stylesheet" TYPE="text/css" HREF='/css/general.css'> <LINK REL="stylesheet" TYPE="text/css" HREF='/css/menu.css'> <link rel="stylesheet" media="all" type="text/css" href="/css/tabbed_pages.css" /> <script type="text/javascript" src="/javascript/jquery.js"></script> <SCRIPT SRC="/javascript/webqtl.js"></SCRIPT> <SCRIPT SRC="/javascript/dhtml.js"></SCRIPT> <SCRIPT SRC="/javascript/jqueryFunction.js"></SCRIPT> <script src="/javascript/tabbed_pages.js" type="text/javascript"></script> </HEAD> <BODY bottommargin="2" leftmargin="2" rightmargin="2" topmargin="2" text=#000000 bgColor=#ffffff > <TABLE cellSpacing=5 cellPadding=4 width="100%" border=0> <TBODY> <TR> <script language="JavaScript" src="/javascript/header.js"></script> </TR> <TR> <TD bgColor=#eeeeee class="solidBorder"> <Table width= "100%" cellSpacing=0 cellPadding=5> <TR> <!-- split from Here --> <!-- Body Start from Here --> <P class="title">OHSU HS-CC Striatum ILM6v1 (Feb11) RankInv<A HREF="/webqtl/main.py?FormID=editHtml"><img src="/images/modify.gif" alt="modify this page" border= 0 valign="middle"></A><BR><BR> Accession number: <A HREF="/webqtl/main.py?FormID=sharinginfo&GN_AccessionId=304">GN304</A></P> <P class="subtitle">Summary:</P> <blockquote> The current study focused on the extent genetic diversity within a species (Mus musculus) affects gene co-expression network structure. To examine this issue, we have created a new mouse resource, a heterogeneous stock (HS) formed from the same eight inbred strains that have been used to create the collaborative cross (CC). The eight inbred strains capture > 90% of the genetic diversity available within the species. For contrast with the HS-CC, a C57BL/6J (B6) × DBA/2J (D2) F2 intercross and the HS4, derived from crossing the B6, D2, BALB/cJ and LP/J strains, were used. Brain (striatum) gene expression data were obtained using the Illumina Mouse WG 6.1 array, and the data sets were interrogated using a weighted gene co-expression network analysis (WGCNA).<br> Read full article: <a href="GN304_Iancu_Hitzemann.pdf" target="_blank">Genetic diversity and striatal gene networks: focus on the heterogeneous stock-collaborative cross (HS-CC) mouse</a>. </blockquote> </TR></TABLE> </TD> </TR> <TR> <TD align=center bgColor=#ddddff class="solidBorder"> <!--Start of footer--> <TABLE width="100%"> <script language='JavaScript' src='/javascript/footer.js'></script> <TR> <TD colspan=4 id="smallsize" align="left"> </TD> </TR> </TABLE> <!--End of footer--> </TD> </TR> </TABLE> <!-- /Footer --> <!-- menu script itself. you should not modify this file --> <script language="JavaScript" src="/javascript/menu_new.js"></script> <!-- items structure. menu hierarchy and links are stored there --> <script language="JavaScript" src="/javascript/menu_items.js"></script> <!-- files with geometry and styles structures --> <script language="JavaScript" src="/javascript/menu_tpl.js"></script> <script language="JavaScript"> <!--// // Note where menu initialization block is located in HTML document. // Don't try to position menu locating menu initialization block in // some table cell or other HTML element. Always put it before </body> // each menu gets two parameters (see demo files) // 1. items structure // 2. geometry structure new menu (MENU_ITEMS, MENU_POS); // make sure files containing definitions for these variables are linked to the document // if you got some javascript error like "MENU_POS is not defined", then you've made syntax // error in menu_tpl.js file or that file isn't linked properly. // also take a look at stylesheets loaded in header in order to set styles //--> </script> </BODY> </HTML>