<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN"> <HTML><HEAD><TITLE>M430 RMA Liver F2 Aug05 / GeneNetwork</TITLE> <META http-equiv=Content-Type content="text/html; charset=iso-8859-1"> <LINK REL="stylesheet" TYPE="text/css" HREF='/css/general.css'> <LINK REL="stylesheet" TYPE="text/css" HREF='/css/menu.css'> </HEAD> <BODY bottommargin="2" leftmargin="2" rightmargin="2" topmargin="2" text=#000000 bgColor=#ffffff> <TABLE cellSpacing=5 cellPadding=4 width="100%" border=0> <TBODY> <TR> <script language="JavaScript" src="/javascript/header.js"></script> </TR> <TR> <TD bgColor=#eeeeee class="solidBorder"> <Table width= "100%" cellSpacing=0 cellPadding=5><TR> <!-- Body Start from Here --> <TD valign="top" height="200" width="100%" bgcolor="#eeeeee"> <P class="title"> (B6 x BTBR)F<SUB class="fs12">2</SUB>-ob/ob Phenotype Database <A HREF="/webqtl/main.py?FormID=editHtml"><img src="/images/modify.gif" alt="modify this page" border= 0 valign="middle"></A></P> <P class="subtitle"> Summary:</P> <Blockquote> <P> The Phenotypes database of August 2005 provides quantitative trait data for 24 phenotypes from a set of 110 F2 animals generated by crossing strains C57BL/6J and BTBR. All F2s are homozygous for the obese (ob) allele of leptin (<I>Lep</I>) on Chr 6. Data were generated at the University of Wisconsin by Alan Attie and colleagues (Stoehr et al. 2000; Lan et al. 2003). This data release complement the liver transcriptome data described in the paper of Lan and colleagues (in submission, 2005). Traits include body weight, insulin and blood sugar levels, and rtPCR results. To review a complete list of the 24 phenotypes simply type in the wildcard character * in the ANY search field. This data set includes values for all 60 selected animals whose liver mRNA has been quantified using the Affymetrix M430A and B arrays, as well as an addition 50 F2 ob/ob animals from the same cross. </P> </Blockquote> <Blockquote>The 110 F<SUB class="fs12">2</SUB>-ob/ob mice were chosen from a larger mapping panel that we created to map diabetes related physiological phenotypes (Stoehr et al. 2000). All 110 of this subsetwere used to map mRNA abundance traits derived by quantitative real-time RT-PCR (Lan et al. 2003). </P> </Blockquote> <P class="subtitle"> Data source acknowledgment:</P> <Blockquote>This project was supported in part by NIH/NIDDK 5803701, NIH/NIDDK 66369-01 and American Diabetes Association 7-03-IG-01 to Alan D. Attie, USDA CSREES grants to the University of Wisconsin-Madison to Brian S. Yandell, and HHMI grant A-53-1200-4 to Christina Kendziorski. </blockquote> <P class="subtitle"> Information about this text file:</P> <Blockquote><P>This text file originally generated by RWW and Alan Attie, August 20, 2005. </P></Blockquote> </TD> <!-- Body End Here --> </TR></TABLE> </TD> </TR> <TR> <TD align=center bgColor=#ddddff class="solidBorder"> <!--Start of footer--> <TABLE width="90%"> <script language='JavaScript' src='/javascript/footer.js'></script> </TABLE> <!--End of footer--> </TD> </TR> </TABLE> <!-- /Footer --> <!-- menu script itself. you should not modify this file --> <script language="JavaScript" src="/javascript/menu_new.js"></script> <!-- items structure. menu hierarchy and links are stored there --> <script language="JavaScript" src="/javascript/menu_items.js"></script> <!-- files with geometry and styles structures --> <script language="JavaScript" src="/javascript/menu_tpl.js"></script> <script language="JavaScript"> <!--// // Note where menu initialization block is located in HTML document. // Don't try to position menu locating menu initialization block in // some table cell or other HTML element. Always put it before </body> // each menu gets two parameters (see demo files) // 1. items structure // 2. geometry structure new menu (MENU_ITEMS, MENU_POS); // make sure files containing definitions for these variables are linked to the document // if you got some javascript error like "MENU_POS is not defined", then you've made syntax // error in menu_tpl.js file or that file isn't linked properly. // also take a look at stylesheets loaded in header in order to set styles //--> </script> </BODY> </HTML>