From 5143738870b8872a915432225acf01508de620ee Mon Sep 17 00:00:00 2001 From: Zachary Sloan Date: Fri, 22 Nov 2013 22:33:22 +0000 Subject: Did some work towards getting the interval mapping page working --- wqflask/wqflask/interval_mapping/__init__.py | 0 .../wqflask/interval_mapping/interval_mapping.py | 20 +- .../wqflask/static/new/javascript/bar_chart.coffee | 25 +- wqflask/wqflask/static/new/javascript/bar_chart.js | 15 +- .../wqflask/static/new/javascript/box_plot.coffee | 45 +- wqflask/wqflask/static/new/javascript/box_plot.js | 83 ++++ .../static/new/javascript/show_trait.coffee | 433 ++----------------- .../wqflask/static/new/javascript/show_trait.js | 477 ++------------------- .../new/javascript/show_trait_mapping_tools.coffee | 26 ++ .../new/javascript/show_trait_mapping_tools.js | 27 ++ wqflask/wqflask/templates/show_trait.html | 1 + .../templates/show_trait_mapping_tools.html | 9 +- wqflask/wqflask/user_manager.py | 30 +- wqflask/wqflask/views.py | 16 +- 14 files changed, 307 insertions(+), 900 deletions(-) create mode 100644 wqflask/wqflask/interval_mapping/__init__.py create mode 100644 wqflask/wqflask/static/new/javascript/box_plot.js (limited to 'wqflask') diff --git a/wqflask/wqflask/interval_mapping/__init__.py b/wqflask/wqflask/interval_mapping/__init__.py new file mode 100644 index 00000000..e69de29b diff --git a/wqflask/wqflask/interval_mapping/interval_mapping.py b/wqflask/wqflask/interval_mapping/interval_mapping.py index aca99cbe..f41ebd2c 100755 --- a/wqflask/wqflask/interval_mapping/interval_mapping.py +++ b/wqflask/wqflask/interval_mapping/interval_mapping.py @@ -37,6 +37,8 @@ class IntervalMapping(object): def __init__(self, start_vars, temp_uuid): + print("TESTING!!!") + #Currently only getting trait data for one trait, but will need #to change this to accept multiple traits once the collection page is implemented helper_functions.get_species_dataset_trait(self, start_vars) @@ -51,6 +53,8 @@ class IntervalMapping(object): self.samples.append(str(sample)) self.vals.append(value) + print("start_vars:", start_vars) + self.set_options(start_vars) self.gen_qtl_results(tempdata) @@ -69,24 +73,24 @@ class IntervalMapping(object): def set_options(self, start_vars): """Sets various options (physical/genetic mapping, # permutations, which chromosome""" - self.plot_scale = start_vars['scale'] + #self.plot_scale = start_vars['scale'] #if self.plotScale == 'physic' and not fd.genotype.Mbmap: # self.plotScale = 'morgan' self.num_permutations = start_vars['num_permutations'] - self.do_bootstrap = start_vars['do_bootstrap'] - self.control_locus = start_vars['control_locus'] - self.selected_chr = start_vars['selected_chr'] - self.weighted_regression = start_vars['weighted'] - self.lrs_lod = start_vars['lrs_lod'] + #self.do_bootstrap = start_vars['do_bootstrap'] + #self.control_locus = start_vars['control_locus'] + self.selected_chr = start_vars['chromosome'] + #self.weighted_regression = start_vars['weighted'] + #self.lrs_lod = start_vars['lrs_lod'] def gen_qtl_results(self, tempdata): """Generates qtl results for plotting interval map""" self.dataset.group.get_markers() - self.dataset.read_genotype_file() + self.dataset.group.read_genotype_file() - samples, values, variances = self.trait.export_informative() + samples, values, variances = self.this_trait.export_informative() if self.control_locus: if self.weighted_regression: self.qtl_results = self.dataset.genotype.regression(strains = samples, diff --git a/wqflask/wqflask/static/new/javascript/bar_chart.coffee b/wqflask/wqflask/static/new/javascript/bar_chart.coffee index 749a7dc0..2c60d3ab 100644 --- a/wqflask/wqflask/static/new/javascript/bar_chart.coffee +++ b/wqflask/wqflask/static/new/javascript/bar_chart.coffee @@ -121,6 +121,10 @@ class Bar_Chart $('.x.axis').remove() @add_x_axis(x_scale) ) + + d3.select("#color_by_trait").on("click", => + @color_by_trait() + ) get_attr_color_dict: () -> @attr_color_dict = {} @@ -299,20 +303,15 @@ class Bar_Chart .text((d) => return d ) - - + color_by_trait: () -> - console.log("Before load") - $('#collections_holder').load('/collections/list #collections_list') - $.colorbox( - inline: true - href: "#collections_holder" + $('#collections_holder').load('/collections/list #collections_list', => + $.colorbox( + inline: true + href: "#collections_holder" + ) ) - console.log("After load") - #$.colorbox({href:"/collections/list"}) - #$.get( - # url: /collections/list - # - #) + + root.Bar_Chart = Bar_Chart \ No newline at end of file diff --git a/wqflask/wqflask/static/new/javascript/bar_chart.js b/wqflask/wqflask/static/new/javascript/bar_chart.js index 20fab15c..03902741 100644 --- a/wqflask/wqflask/static/new/javascript/bar_chart.js +++ b/wqflask/wqflask/static/new/javascript/bar_chart.js @@ -125,6 +125,9 @@ return _this.add_x_axis(x_scale); } }); + d3.select("#color_by_trait").on("click", function() { + return _this.color_by_trait(); + }); } Bar_Chart.prototype.get_attr_color_dict = function() { @@ -318,13 +321,13 @@ }; Bar_Chart.prototype.color_by_trait = function() { - console.log("Before load"); - $('#collections_holder').load('/collections/list #collections_list'); - $.colorbox({ - inline: true, - href: "#collections_holder" + var _this = this; + return $('#collections_holder').load('/collections/list #collections_list', function() { + return $.colorbox({ + inline: true, + href: "#collections_holder" + }); }); - return console.log("After load"); }; return Bar_Chart; diff --git a/wqflask/wqflask/static/new/javascript/box_plot.coffee b/wqflask/wqflask/static/new/javascript/box_plot.coffee index 562bd1dc..e9035456 100644 --- a/wqflask/wqflask/static/new/javascript/box_plot.coffee +++ b/wqflask/wqflask/static/new/javascript/box_plot.coffee @@ -5,46 +5,53 @@ class Box_Plot @get_samples() @margin = {top: 10, right: 50, bottom: 20, left: 50} - @plot_width = 120 - @margin.left - @margin.right + @plot_width = 200 - @margin.left - @margin.right @plot_height = 500 - @margin.top - @margin.bottom @min = d3.min(@sample_vals) - @max = d3.max(@sample_vals) * 1.1 + @max = d3.max(@sample_vals) @svg = @create_svg() - @enter_data() - + get_samples: () -> - @sample_names = (sample.name for sample in @sample_list when sample.value != null) @sample_vals = (sample.value for sample in @sample_list when sample.value != null) - @samples = _.zip(@sample_names, @sample_vals) - create_svg: () -> d3.chart.box() - .whiskers(@inter_quartile_range(1.5)) - .width(@plot_width) - .height(@plot_height) - .domain([@min, @max]) - + create_svg: () -> + svg = d3.box() + .whiskers(@inter_quartile_range(1.5)) + .width(@plot_width) + .height(@plot_height) + .domain([@min, @max]) + return svg + enter_data: () -> d3.select("#box_plot").selectAll("svg") - .data(@sample_vals) + .data([@sample_vals]) .enter().append("svg:svg") .attr("class", "box") .attr("width", @plot_width) .attr("height", @plot_height) + .append("svg:g") .call(@svg) inter_quartile_range: (k) -> return (d, i) => - q1 = d.quartiles[0], - q3 = d.quartiles[2], + console.log("iqr d:", d) + q1 = d.quartiles[0] + q3 = d.quartiles[2] inter_quartile_range = (q3 - q1) * k - i = -1 + console.log("iqr:", inter_quartile_range) + i = 0 j = d.length - while (d[++i] < q1 - inter_quartile_range) - while (d[--j] > q3 + inter_quartile_range) + console.log("d[-1]:", d[1]) + console.log("q1 - iqr:", q1 - inter_quartile_range) + i++ while (d[i] < q1 - inter_quartile_range) + j-- while (d[j] > q3 + inter_quartile_range) + #while (d[++i] < q1 - inter_quartile_range + #while d[--j] > q3 + inter_quartile_range + console.log("[i, j]", [i, j]) return [i, j] - \ No newline at end of file +root.Box_Plot = Box_Plot \ No newline at end of file diff --git a/wqflask/wqflask/static/new/javascript/box_plot.js b/wqflask/wqflask/static/new/javascript/box_plot.js new file mode 100644 index 00000000..2dd624e1 --- /dev/null +++ b/wqflask/wqflask/static/new/javascript/box_plot.js @@ -0,0 +1,83 @@ +// Generated by CoffeeScript 1.6.1 +(function() { + var Box_Plot, root; + + root = typeof exports !== "undefined" && exports !== null ? exports : this; + + Box_Plot = (function() { + + function Box_Plot(sample_list, sample_group) { + this.sample_list = sample_list; + this.sample_group = sample_group; + this.get_samples(); + this.margin = { + top: 10, + right: 50, + bottom: 20, + left: 50 + }; + this.plot_width = 200 - this.margin.left - this.margin.right; + this.plot_height = 500 - this.margin.top - this.margin.bottom; + this.min = d3.min(this.sample_vals); + this.max = d3.max(this.sample_vals); + this.svg = this.create_svg(); + this.enter_data(); + } + + Box_Plot.prototype.get_samples = function() { + var sample; + return this.sample_vals = (function() { + var _i, _len, _ref, _results; + _ref = this.sample_list; + _results = []; + for (_i = 0, _len = _ref.length; _i < _len; _i++) { + sample = _ref[_i]; + if (sample.value !== null) { + _results.push(sample.value); + } + } + return _results; + }).call(this); + }; + + Box_Plot.prototype.create_svg = function() { + var svg; + svg = d3.box().whiskers(this.inter_quartile_range(1.5)).width(this.plot_width).height(this.plot_height).domain([this.min, this.max]); + return svg; + }; + + Box_Plot.prototype.enter_data = function() { + return d3.select("#box_plot").selectAll("svg").data([this.sample_vals]).enter().append("svg:svg").attr("class", "box").attr("width", this.plot_width).attr("height", this.plot_height).append("svg:g").call(this.svg); + }; + + Box_Plot.prototype.inter_quartile_range = function(k) { + var _this = this; + return function(d, i) { + var inter_quartile_range, j, q1, q3; + console.log("iqr d:", d); + q1 = d.quartiles[0]; + q3 = d.quartiles[2]; + inter_quartile_range = (q3 - q1) * k; + console.log("iqr:", inter_quartile_range); + i = 0; + j = d.length; + console.log("d[-1]:", d[1]); + console.log("q1 - iqr:", q1 - inter_quartile_range); + while (d[i] < q1 - inter_quartile_range) { + i++; + } + while (d[j] > q3 + inter_quartile_range) { + j--; + } + console.log("[i, j]", [i, j]); + return [i, j]; + }; + }; + + return Box_Plot; + + })(); + + root.Box_Plot = Box_Plot; + +}).call(this); diff --git a/wqflask/wqflask/static/new/javascript/show_trait.coffee b/wqflask/wqflask/static/new/javascript/show_trait.coffee index 8bcca85d..7d23345f 100644 --- a/wqflask/wqflask/static/new/javascript/show_trait.coffee +++ b/wqflask/wqflask/static/new/javascript/show_trait.coffee @@ -59,373 +59,6 @@ Stat_Table_Rows = [ ] $ -> - class Bar_Chart - constructor: (@sample_list, @sample_group) -> - @get_samples() - console.log("sample names:", @sample_names) - if @sample_attr_vals.length > 0 - @get_distinct_attr_vals() - @get_attr_color_dict() - - #Used to calculate the bottom margin so sample names aren't cut off - longest_sample_name = d3.max(sample.length for sample in @sample_names) - - @margin = {top: 20, right: 20, bottom: longest_sample_name * 7, left: 40} - @plot_width = @sample_vals.length * 15 - @margin.left - @margin.right - @plot_height = 500 - @margin.top - @margin.bottom - - @x_buffer = @plot_width/20 - @y_buffer = @plot_height/20 - - @y_min = d3.min(@sample_vals) - @y_max = d3.max(@sample_vals) * 1.1 - - @svg = @create_svg() - - @plot_height -= @y_buffer - @create_scales() - @create_graph() - - d3.select("#color_attribute").on("change", => - attribute = $("#color_attribute").val() - if $("#update_bar_chart").html() == 'Sort By Name' - @svg.selectAll(".bar") - .data(@sorted_samples()) - .transition() - .duration(1000) - .style("fill", (d) => - if attribute == "None" - return "steelblue" - else - return @attr_color_dict[attribute][d[2][attribute]] - ) - .select("title") - .text((d) => - return d[1] - ) - else - @svg.selectAll(".bar") - .data(@samples) - .transition() - .duration(1000) - .style("fill", (d) => - if attribute == "None" - return "steelblue" - else - return @attr_color_dict[attribute][d[2][attribute]] - ) - @add_legend(attribute, @distinct_attr_vals[attribute]) - ) - - - d3.select("#update_bar_chart").on("click", => - if @attributes.length > 0 - attribute = $("#color_attribute").val() - if $("#update_bar_chart").html() == 'Sort By Value' - $("#update_bar_chart").html('Sort By Name') - sortItems = (a, b) -> - return a[1] - b[1] - - @svg.selectAll(".bar") - .data(@sorted_samples()) - .transition() - .duration(1000) - .attr("y", (d) => - return @y_scale(d[1]) - ) - .attr("height", (d) => - return @plot_height - @y_scale(d[1]) - ) - .style("fill", (d) => - if @attributes.length > 0 - return @attr_color_dict[attribute][d[2][attribute]] - else - return "steelblue" - ) - .select("title") - .text((d) => - return d[1] - ) - sorted_sample_names = (sample[0] for sample in @sorted_samples()) - x_scale = d3.scale.ordinal() - .domain(sorted_sample_names) - .rangeBands([0, @plot_width], .1) - $('.x.axis').remove() - @add_x_axis(x_scale) - else - $("#update_bar_chart").html('Sort By Value') - @svg.selectAll(".bar") - .data(@samples) - .transition() - .duration(1000) - .attr("y", (d) => - return @y_scale(d[1]) - ) - .attr("height", (d) => - return @plot_height - @y_scale(d[1]) - ) - .style("fill", (d) => - if @attributes.length > 0 - return @attr_color_dict[attribute][d[2][attribute]] - else - return "steelblue" - ) - .select("title") - .text((d) => - return d[1] - ) - x_scale = d3.scale.ordinal() - .domain(@sample_names) - .rangeBands([0, @plot_width], .1) - $('.x.axis').remove() - @add_x_axis(x_scale) - ) - - d3.select("#color_by_trait").on("click", => - @color_by_trait() - ) - - get_attr_color_dict: () -> - @attr_color_dict = {} - console.log("distinct_attr_vals:", @distinct_attr_vals) - for own key, distinct_vals of @distinct_attr_vals - this_color_dict = {} - if distinct_vals.length < 10 - color = d3.scale.category10() - for value, i in distinct_vals - this_color_dict[value] = color(i) - else - console.log("distinct_values:", distinct_vals) - if _.every(distinct_vals, (d) => - if isNaN(d) - return false - else - return true - ) - color_range = d3.scale.linear() - .domain([d3.min(distinct_vals), - d3.max(distinct_vals)]) - .range([0,4]) - for value, i in distinct_vals - console.log("color_range(value):", color_range(parseInt(value))) - this_color_dict[value] = d3.rgb("lightblue").darker(color_range(parseInt(value))) - #this_color_dict[value] = "rgb(0, 0, " + color_range(parseInt(value)) + ")" - @attr_color_dict[key] = this_color_dict - - get_samples: () -> - @sample_names = (sample.name for sample in @sample_list when sample.value != null) - @sample_vals = (sample.value for sample in @sample_list when sample.value != null) - @attributes = (key for key of @sample_list[0]["extra_attributes"]) - console.log("attributes:", @attributes) - @sample_attr_vals = [] - if @attributes.length > 0 - for sample in @sample_list - attr_vals = {} - for attribute in @attributes - attr_vals[attribute] = sample["extra_attributes"][attribute] - @sample_attr_vals.push(attr_vals) - @samples = _.zip(@sample_names, @sample_vals, @sample_attr_vals) - - get_distinct_attr_vals: () -> - @distinct_attr_vals = {} - for sample in @sample_attr_vals - for attribute of sample - if not @distinct_attr_vals[attribute] - @distinct_attr_vals[attribute] = [] - if sample[attribute] not in @distinct_attr_vals[attribute] - @distinct_attr_vals[attribute].push(sample[attribute]) - #console.log("distinct_attr_vals:", @distinct_attr_vals) - - create_svg: () -> - svg = d3.select("#bar_chart") - .append("svg") - .attr("class", "bar_chart") - .attr("width", @plot_width + @margin.left + @margin.right) - .attr("height", @plot_height + @margin.top + @margin.bottom) - .append("g") - .attr("transform", "translate(" + @margin.left + "," + @margin.top + ")") - - return svg - - create_scales: () -> - @x_scale = d3.scale.ordinal() - .domain(@sample_names) - .rangeBands([0, @plot_width], .1) - - @y_scale = d3.scale.linear() - .domain([@y_min * 0.75, @y_max]) - .range([@plot_height, @y_buffer]) - - create_graph: () -> - - #@add_border() - @add_x_axis(@x_scale) - @add_y_axis() - - @add_bars() - - add_x_axis: (scale) -> - xAxis = d3.svg.axis() - .scale(scale) - .orient("bottom"); - - @svg.append("g") - .attr("class", "x axis") - .attr("transform", "translate(0," + @plot_height + ")") - .call(xAxis) - .selectAll("text") - .style("text-anchor", "end") - .style("font-size", "12px") - .attr("dx", "-.8em") - .attr("dy", "-.3em") - .attr("transform", (d) => - return "rotate(-90)" - ) - - add_y_axis: () -> - yAxis = d3.svg.axis() - .scale(@y_scale) - .orient("left") - .ticks(5) - - @svg.append("g") - .attr("class", "y axis") - .call(yAxis) - .append("text") - .attr("transform", "rotate(-90)") - .attr("y", 6) - .attr("dy", ".71em") - .style("text-anchor", "end") - - add_bars: () -> - @svg.selectAll(".bar") - .data(@samples) - .enter().append("rect") - .style("fill", "steelblue") - .attr("class", "bar") - .attr("x", (d) => - return @x_scale(d[0]) - ) - .attr("width", @x_scale.rangeBand()) - .attr("y", (d) => - return @y_scale(d[1]) - ) - .attr("height", (d) => - return @plot_height - @y_scale(d[1]) - ) - .append("svg:title") - .text((d) => - return d[1] - ) - - sorted_samples: () -> - #if @sample_attr_vals.length > 0 - sample_list = _.zip(@sample_names, @sample_vals, @sample_attr_vals) - #else - # sample_list = _.zip(@sample_names, @sample_vals) - sorted = _.sortBy(sample_list, (sample) => - return sample[1] - ) - console.log("sorted:", sorted) - return sorted - - add_legend: (attribute, distinct_vals) -> - legend = @svg.append("g") - .attr("class", "legend") - .attr("height", 100) - .attr("width", 100) - .attr('transform', 'translate(-20,50)') - - legend_rect = legend.selectAll('rect') - .data(distinct_vals) - .enter() - .append("rect") - .attr("x", @plot_width - 65) - .attr("width", 10) - .attr("height", 10) - .attr("y", (d, i) => - return i * 20 - ) - .style("fill", (d) => - console.log("TEST:", @attr_color_dict[attribute][d]) - return @attr_color_dict[attribute][d] - ) - - legend_text = legend.selectAll('text') - .data(distinct_vals) - .enter() - .append("text") - .attr("x", @plot_width - 52) - .attr("y", (d, i) => - return i*20 + 9 - ) - .text((d) => - return d - ) - - color_by_trait: () -> - $('#collections_holder').load('/collections/list #collections_list', => - $.colorbox( - inline: true - href: "#collections_holder" - ) - ) - - class Box_Plot - constructor: (@sample_list, @sample_group) -> - @get_samples() - - @margin = {top: 10, right: 50, bottom: 20, left: 50} - @plot_width = 200 - @margin.left - @margin.right - @plot_height = 500 - @margin.top - @margin.bottom - - @min = d3.min(@sample_vals) - @max = d3.max(@sample_vals) - - @svg = @create_svg() - @enter_data() - - - get_samples: () -> - @sample_vals = (sample.value for sample in @sample_list when sample.value != null) - - create_svg: () -> - svg = d3.box() - .whiskers(@inter_quartile_range(1.5)) - .width(@plot_width) - .height(@plot_height) - .domain([@min, @max]) - return svg - - enter_data: () -> - d3.select("#box_plot").selectAll("svg") - .data([@sample_vals]) - .enter().append("svg:svg") - .attr("class", "box") - .attr("width", @plot_width) - .attr("height", @plot_height) - .append("svg:g") - .call(@svg) - - inter_quartile_range: (k) -> - return (d, i) => - console.log("iqr d:", d) - q1 = d.quartiles[0] - q3 = d.quartiles[2] - inter_quartile_range = (q3 - q1) * k - console.log("iqr:", inter_quartile_range) - i = 0 - j = d.length - console.log("d[-1]:", d[1]) - console.log("q1 - iqr:", q1 - inter_quartile_range) - i++ while (d[i] < q1 - inter_quartile_range) - j-- while (d[j] > q3 + inter_quartile_range) - #while (d[++i] < q1 - inter_quartile_range - #while d[--j] > q3 + inter_quartile_range - console.log("[i, j]", [i, j]) - return [i, j] - - sample_lists = js_data.sample_lists sample_group_types = js_data.sample_group_types @@ -504,39 +137,6 @@ $ -> console.log("Calling change_stats_value") change_stats_value(sample_sets, category, row.vn, row.digits) - edit_data_change = -> - already_seen = {} - sample_sets = - samples_primary: new Stats([]) - samples_other: new Stats([]) - samples_all: new Stats([]) - - console.log("at beginning:", sample_sets) - - tables = ['samples_primary', 'samples_other'] - for table in tables - rows = $("#" + table).find('tr') - for row in rows - name = $(row).find('.edit_sample_sample_name').html() - name = $.trim(name) - real_value = $(row).find('.edit_sample_value').val() - console.log("real_value:", real_value) - checkbox = $(row).find(".edit_sample_checkbox") - checked = $(checkbox).attr('checked') - - if checked and is_number(real_value) and real_value != "" - console.log("in the iffy if") - real_value = parseFloat(real_value) - - sample_sets[table].add_value(real_value) - console.log("checking name of:", name) - if not (name of already_seen) - console.log("haven't seen") - sample_sets['samples_all'].add_value(real_value) - already_seen[name] = true - console.log("towards end:", sample_sets) - update_stat_values(sample_sets) - make_table = -> header = " " @@ -585,6 +185,38 @@ $ -> processed += value return processed + edit_data_change = -> + already_seen = {} + sample_sets = + samples_primary: new Stats([]) + samples_other: new Stats([]) + samples_all: new Stats([]) + + console.log("at beginning:", sample_sets) + + tables = ['samples_primary', 'samples_other'] + for table in tables + rows = $("#" + table).find('tr') + for row in rows + name = $(row).find('.edit_sample_sample_name').html() + name = $.trim(name) + real_value = $(row).find('.edit_sample_value').val() + console.log("real_value:", real_value) + checkbox = $(row).find(".edit_sample_checkbox") + checked = $(checkbox).attr('checked') + + if checked and is_number(real_value) and real_value != "" + console.log("in the iffy if") + real_value = parseFloat(real_value) + + sample_sets[table].add_value(real_value) + console.log("checking name of:", name) + if not (name of already_seen) + console.log("haven't seen") + sample_sets['samples_all'].add_value(real_value) + already_seen[name] = true + console.log("towards end:", sample_sets) + update_stat_values(sample_sets) show_hide_outliers = -> console.log("FOOBAR in beginning of show_hide_outliers") @@ -613,7 +245,6 @@ $ -> $('select[name=corr_method]').change(on_corr_method_change) - ##End Calculate Correlations Code ##Populate Samples Attribute Values Code diff --git a/wqflask/wqflask/static/new/javascript/show_trait.js b/wqflask/wqflask/static/new/javascript/show_trait.js index b562bfe2..718e365a 100644 --- a/wqflask/wqflask/static/new/javascript/show_trait.js +++ b/wqflask/wqflask/static/new/javascript/show_trait.js @@ -2,7 +2,6 @@ (function() { var Stat_Table_Rows, is_number, __hasProp = {}.hasOwnProperty, - __indexOf = [].indexOf || function(item) { for (var i = 0, l = this.length; i < l; i++) { if (i in this && this[i] === item) return i; } return -1; }, __slice = [].slice; console.log("start_b"); @@ -57,407 +56,7 @@ ]; $(function() { - var Bar_Chart, Box_Plot, block_by_attribute_value, block_by_index, block_outliers, change_stats_value, create_value_dropdown, edit_data_change, export_sample_table_data, get_sample_table_data, hide_no_value, hide_tabs, make_table, on_corr_method_change, populate_sample_attributes_values_dropdown, process_id, reset_samples_table, sample_group_types, sample_lists, show_hide_outliers, stats_mdp_change, update_stat_values; - Bar_Chart = (function() { - - function Bar_Chart(sample_list, sample_group) { - var longest_sample_name, sample, - _this = this; - this.sample_list = sample_list; - this.sample_group = sample_group; - this.get_samples(); - console.log("sample names:", this.sample_names); - if (this.sample_attr_vals.length > 0) { - this.get_distinct_attr_vals(); - this.get_attr_color_dict(); - } - longest_sample_name = d3.max((function() { - var _i, _len, _ref, _results; - _ref = this.sample_names; - _results = []; - for (_i = 0, _len = _ref.length; _i < _len; _i++) { - sample = _ref[_i]; - _results.push(sample.length); - } - return _results; - }).call(this)); - this.margin = { - top: 20, - right: 20, - bottom: longest_sample_name * 7, - left: 40 - }; - this.plot_width = this.sample_vals.length * 15 - this.margin.left - this.margin.right; - this.plot_height = 500 - this.margin.top - this.margin.bottom; - this.x_buffer = this.plot_width / 20; - this.y_buffer = this.plot_height / 20; - this.y_min = d3.min(this.sample_vals); - this.y_max = d3.max(this.sample_vals) * 1.1; - this.svg = this.create_svg(); - this.plot_height -= this.y_buffer; - this.create_scales(); - this.create_graph(); - d3.select("#color_attribute").on("change", function() { - var attribute; - attribute = $("#color_attribute").val(); - if ($("#update_bar_chart").html() === 'Sort By Name') { - _this.svg.selectAll(".bar").data(_this.sorted_samples()).transition().duration(1000).style("fill", function(d) { - if (attribute === "None") { - return "steelblue"; - } else { - return _this.attr_color_dict[attribute][d[2][attribute]]; - } - }).select("title").text(function(d) { - return d[1]; - }); - } else { - _this.svg.selectAll(".bar").data(_this.samples).transition().duration(1000).style("fill", function(d) { - if (attribute === "None") { - return "steelblue"; - } else { - return _this.attr_color_dict[attribute][d[2][attribute]]; - } - }); - } - return _this.add_legend(attribute, _this.distinct_attr_vals[attribute]); - }); - d3.select("#update_bar_chart").on("click", function() { - var attribute, sortItems, sorted_sample_names, x_scale; - if (_this.attributes.length > 0) { - attribute = $("#color_attribute").val(); - } - if ($("#update_bar_chart").html() === 'Sort By Value') { - $("#update_bar_chart").html('Sort By Name'); - sortItems = function(a, b) { - return a[1] - b[1]; - }; - _this.svg.selectAll(".bar").data(_this.sorted_samples()).transition().duration(1000).attr("y", function(d) { - return _this.y_scale(d[1]); - }).attr("height", function(d) { - return _this.plot_height - _this.y_scale(d[1]); - }).style("fill", function(d) { - if (_this.attributes.length > 0) { - return _this.attr_color_dict[attribute][d[2][attribute]]; - } else { - return "steelblue"; - } - }).select("title").text(function(d) { - return d[1]; - }); - sorted_sample_names = (function() { - var _i, _len, _ref, _results; - _ref = this.sorted_samples(); - _results = []; - for (_i = 0, _len = _ref.length; _i < _len; _i++) { - sample = _ref[_i]; - _results.push(sample[0]); - } - return _results; - }).call(_this); - x_scale = d3.scale.ordinal().domain(sorted_sample_names).rangeBands([0, _this.plot_width], .1); - $('.x.axis').remove(); - return _this.add_x_axis(x_scale); - } else { - $("#update_bar_chart").html('Sort By Value'); - _this.svg.selectAll(".bar").data(_this.samples).transition().duration(1000).attr("y", function(d) { - return _this.y_scale(d[1]); - }).attr("height", function(d) { - return _this.plot_height - _this.y_scale(d[1]); - }).style("fill", function(d) { - if (_this.attributes.length > 0) { - return _this.attr_color_dict[attribute][d[2][attribute]]; - } else { - return "steelblue"; - } - }).select("title").text(function(d) { - return d[1]; - }); - x_scale = d3.scale.ordinal().domain(_this.sample_names).rangeBands([0, _this.plot_width], .1); - $('.x.axis').remove(); - return _this.add_x_axis(x_scale); - } - }); - d3.select("#color_by_trait").on("click", function() { - return _this.color_by_trait(); - }); - } - - Bar_Chart.prototype.get_attr_color_dict = function() { - var color, color_range, distinct_vals, i, key, this_color_dict, value, _i, _j, _len, _len1, _ref, _results, - _this = this; - this.attr_color_dict = {}; - console.log("distinct_attr_vals:", this.distinct_attr_vals); - _ref = this.distinct_attr_vals; - _results = []; - for (key in _ref) { - if (!__hasProp.call(_ref, key)) continue; - distinct_vals = _ref[key]; - this_color_dict = {}; - if (distinct_vals.length < 10) { - color = d3.scale.category10(); - for (i = _i = 0, _len = distinct_vals.length; _i < _len; i = ++_i) { - value = distinct_vals[i]; - this_color_dict[value] = color(i); - } - } else { - console.log("distinct_values:", distinct_vals); - if (_.every(distinct_vals, function(d) { - if (isNaN(d)) { - return false; - } else { - return true; - } - })) { - color_range = d3.scale.linear().domain([d3.min(distinct_vals), d3.max(distinct_vals)]).range([0, 4]); - for (i = _j = 0, _len1 = distinct_vals.length; _j < _len1; i = ++_j) { - value = distinct_vals[i]; - console.log("color_range(value):", color_range(parseInt(value))); - this_color_dict[value] = d3.rgb("lightblue").darker(color_range(parseInt(value))); - } - } - } - _results.push(this.attr_color_dict[key] = this_color_dict); - } - return _results; - }; - - Bar_Chart.prototype.get_samples = function() { - var attr_vals, attribute, key, sample, _i, _j, _len, _len1, _ref, _ref1; - this.sample_names = (function() { - var _i, _len, _ref, _results; - _ref = this.sample_list; - _results = []; - for (_i = 0, _len = _ref.length; _i < _len; _i++) { - sample = _ref[_i]; - if (sample.value !== null) { - _results.push(sample.name); - } - } - return _results; - }).call(this); - this.sample_vals = (function() { - var _i, _len, _ref, _results; - _ref = this.sample_list; - _results = []; - for (_i = 0, _len = _ref.length; _i < _len; _i++) { - sample = _ref[_i]; - if (sample.value !== null) { - _results.push(sample.value); - } - } - return _results; - }).call(this); - this.attributes = (function() { - var _results; - _results = []; - for (key in this.sample_list[0]["extra_attributes"]) { - _results.push(key); - } - return _results; - }).call(this); - console.log("attributes:", this.attributes); - this.sample_attr_vals = []; - if (this.attributes.length > 0) { - _ref = this.sample_list; - for (_i = 0, _len = _ref.length; _i < _len; _i++) { - sample = _ref[_i]; - attr_vals = {}; - _ref1 = this.attributes; - for (_j = 0, _len1 = _ref1.length; _j < _len1; _j++) { - attribute = _ref1[_j]; - attr_vals[attribute] = sample["extra_attributes"][attribute]; - } - this.sample_attr_vals.push(attr_vals); - } - } - return this.samples = _.zip(this.sample_names, this.sample_vals, this.sample_attr_vals); - }; - - Bar_Chart.prototype.get_distinct_attr_vals = function() { - var attribute, sample, _i, _len, _ref, _results; - this.distinct_attr_vals = {}; - _ref = this.sample_attr_vals; - _results = []; - for (_i = 0, _len = _ref.length; _i < _len; _i++) { - sample = _ref[_i]; - _results.push((function() { - var _ref1, _results1; - _results1 = []; - for (attribute in sample) { - if (!this.distinct_attr_vals[attribute]) { - this.distinct_attr_vals[attribute] = []; - } - if (_ref1 = sample[attribute], __indexOf.call(this.distinct_attr_vals[attribute], _ref1) < 0) { - _results1.push(this.distinct_attr_vals[attribute].push(sample[attribute])); - } else { - _results1.push(void 0); - } - } - return _results1; - }).call(this)); - } - return _results; - }; - - Bar_Chart.prototype.create_svg = function() { - var svg; - svg = d3.select("#bar_chart").append("svg").attr("class", "bar_chart").attr("width", this.plot_width + this.margin.left + this.margin.right).attr("height", this.plot_height + this.margin.top + this.margin.bottom).append("g").attr("transform", "translate(" + this.margin.left + "," + this.margin.top + ")"); - return svg; - }; - - Bar_Chart.prototype.create_scales = function() { - this.x_scale = d3.scale.ordinal().domain(this.sample_names).rangeBands([0, this.plot_width], .1); - return this.y_scale = d3.scale.linear().domain([this.y_min * 0.75, this.y_max]).range([this.plot_height, this.y_buffer]); - }; - - Bar_Chart.prototype.create_graph = function() { - this.add_x_axis(this.x_scale); - this.add_y_axis(); - return this.add_bars(); - }; - - Bar_Chart.prototype.add_x_axis = function(scale) { - var xAxis, - _this = this; - xAxis = d3.svg.axis().scale(scale).orient("bottom"); - return this.svg.append("g").attr("class", "x axis").attr("transform", "translate(0," + this.plot_height + ")").call(xAxis).selectAll("text").style("text-anchor", "end").style("font-size", "12px").attr("dx", "-.8em").attr("dy", "-.3em").attr("transform", function(d) { - return "rotate(-90)"; - }); - }; - - Bar_Chart.prototype.add_y_axis = function() { - var yAxis; - yAxis = d3.svg.axis().scale(this.y_scale).orient("left").ticks(5); - return this.svg.append("g").attr("class", "y axis").call(yAxis).append("text").attr("transform", "rotate(-90)").attr("y", 6).attr("dy", ".71em").style("text-anchor", "end"); - }; - - Bar_Chart.prototype.add_bars = function() { - var _this = this; - return this.svg.selectAll(".bar").data(this.samples).enter().append("rect").style("fill", "steelblue").attr("class", "bar").attr("x", function(d) { - return _this.x_scale(d[0]); - }).attr("width", this.x_scale.rangeBand()).attr("y", function(d) { - return _this.y_scale(d[1]); - }).attr("height", function(d) { - return _this.plot_height - _this.y_scale(d[1]); - }).append("svg:title").text(function(d) { - return d[1]; - }); - }; - - Bar_Chart.prototype.sorted_samples = function() { - var sample_list, sorted, - _this = this; - sample_list = _.zip(this.sample_names, this.sample_vals, this.sample_attr_vals); - sorted = _.sortBy(sample_list, function(sample) { - return sample[1]; - }); - console.log("sorted:", sorted); - return sorted; - }; - - Bar_Chart.prototype.add_legend = function(attribute, distinct_vals) { - var legend, legend_rect, legend_text, - _this = this; - legend = this.svg.append("g").attr("class", "legend").attr("height", 100).attr("width", 100).attr('transform', 'translate(-20,50)'); - legend_rect = legend.selectAll('rect').data(distinct_vals).enter().append("rect").attr("x", this.plot_width - 65).attr("width", 10).attr("height", 10).attr("y", function(d, i) { - return i * 20; - }).style("fill", function(d) { - console.log("TEST:", _this.attr_color_dict[attribute][d]); - return _this.attr_color_dict[attribute][d]; - }); - return legend_text = legend.selectAll('text').data(distinct_vals).enter().append("text").attr("x", this.plot_width - 52).attr("y", function(d, i) { - return i * 20 + 9; - }).text(function(d) { - return d; - }); - }; - - Bar_Chart.prototype.color_by_trait = function() { - var _this = this; - return $('#collections_holder').load('/collections/list #collections_list', function() { - return $.colorbox({ - inline: true, - href: "#collections_holder" - }); - }); - }; - - return Bar_Chart; - - })(); - Box_Plot = (function() { - - function Box_Plot(sample_list, sample_group) { - this.sample_list = sample_list; - this.sample_group = sample_group; - this.get_samples(); - this.margin = { - top: 10, - right: 50, - bottom: 20, - left: 50 - }; - this.plot_width = 200 - this.margin.left - this.margin.right; - this.plot_height = 500 - this.margin.top - this.margin.bottom; - this.min = d3.min(this.sample_vals); - this.max = d3.max(this.sample_vals); - this.svg = this.create_svg(); - this.enter_data(); - } - - Box_Plot.prototype.get_samples = function() { - var sample; - return this.sample_vals = (function() { - var _i, _len, _ref, _results; - _ref = this.sample_list; - _results = []; - for (_i = 0, _len = _ref.length; _i < _len; _i++) { - sample = _ref[_i]; - if (sample.value !== null) { - _results.push(sample.value); - } - } - return _results; - }).call(this); - }; - - Box_Plot.prototype.create_svg = function() { - var svg; - svg = d3.box().whiskers(this.inter_quartile_range(1.5)).width(this.plot_width).height(this.plot_height).domain([this.min, this.max]); - return svg; - }; - - Box_Plot.prototype.enter_data = function() { - return d3.select("#box_plot").selectAll("svg").data([this.sample_vals]).enter().append("svg:svg").attr("class", "box").attr("width", this.plot_width).attr("height", this.plot_height).append("svg:g").call(this.svg); - }; - - Box_Plot.prototype.inter_quartile_range = function(k) { - var _this = this; - return function(d, i) { - var inter_quartile_range, j, q1, q3; - console.log("iqr d:", d); - q1 = d.quartiles[0]; - q3 = d.quartiles[2]; - inter_quartile_range = (q3 - q1) * k; - console.log("iqr:", inter_quartile_range); - i = 0; - j = d.length; - console.log("d[-1]:", d[1]); - console.log("q1 - iqr:", q1 - inter_quartile_range); - while (d[i] < q1 - inter_quartile_range) { - i++; - } - while (d[j] > q3 + inter_quartile_range) { - j--; - } - console.log("[i, j]", [i, j]); - return [i, j]; - }; - }; - - return Box_Plot; - - })(); + var block_by_attribute_value, block_by_index, block_outliers, change_stats_value, create_value_dropdown, edit_data_change, export_sample_table_data, get_sample_table_data, hide_no_value, hide_tabs, make_table, on_corr_method_change, populate_sample_attributes_values_dropdown, process_id, reset_samples_table, sample_group_types, sample_lists, show_hide_outliers, stats_mdp_change, update_stat_values; sample_lists = js_data.sample_lists; sample_group_types = js_data.sample_group_types; new Bar_Chart(sample_lists[0]); @@ -546,43 +145,6 @@ } return _results; }; - edit_data_change = function() { - var already_seen, checkbox, checked, name, real_value, row, rows, sample_sets, table, tables, _i, _j, _len, _len1; - already_seen = {}; - sample_sets = { - samples_primary: new Stats([]), - samples_other: new Stats([]), - samples_all: new Stats([]) - }; - console.log("at beginning:", sample_sets); - tables = ['samples_primary', 'samples_other']; - for (_i = 0, _len = tables.length; _i < _len; _i++) { - table = tables[_i]; - rows = $("#" + table).find('tr'); - for (_j = 0, _len1 = rows.length; _j < _len1; _j++) { - row = rows[_j]; - name = $(row).find('.edit_sample_sample_name').html(); - name = $.trim(name); - real_value = $(row).find('.edit_sample_value').val(); - console.log("real_value:", real_value); - checkbox = $(row).find(".edit_sample_checkbox"); - checked = $(checkbox).attr('checked'); - if (checked && is_number(real_value) && real_value !== "") { - console.log("in the iffy if"); - real_value = parseFloat(real_value); - sample_sets[table].add_value(real_value); - console.log("checking name of:", name); - if (!(name in already_seen)) { - console.log("haven't seen"); - sample_sets['samples_all'].add_value(real_value); - already_seen[name] = true; - } - } - } - } - console.log("towards end:", sample_sets); - return update_stat_values(sample_sets); - }; make_table = function() { var header, key, row, row_line, table, the_id, the_rows, value, _i, _len, _ref, _ref1; header = " "; @@ -645,6 +207,43 @@ } return processed; }; + edit_data_change = function() { + var already_seen, checkbox, checked, name, real_value, row, rows, sample_sets, table, tables, _i, _j, _len, _len1; + already_seen = {}; + sample_sets = { + samples_primary: new Stats([]), + samples_other: new Stats([]), + samples_all: new Stats([]) + }; + console.log("at beginning:", sample_sets); + tables = ['samples_primary', 'samples_other']; + for (_i = 0, _len = tables.length; _i < _len; _i++) { + table = tables[_i]; + rows = $("#" + table).find('tr'); + for (_j = 0, _len1 = rows.length; _j < _len1; _j++) { + row = rows[_j]; + name = $(row).find('.edit_sample_sample_name').html(); + name = $.trim(name); + real_value = $(row).find('.edit_sample_value').val(); + console.log("real_value:", real_value); + checkbox = $(row).find(".edit_sample_checkbox"); + checked = $(checkbox).attr('checked'); + if (checked && is_number(real_value) && real_value !== "") { + console.log("in the iffy if"); + real_value = parseFloat(real_value); + sample_sets[table].add_value(real_value); + console.log("checking name of:", name); + if (!(name in already_seen)) { + console.log("haven't seen"); + sample_sets['samples_all'].add_value(real_value); + already_seen[name] = true; + } + } + } + } + console.log("towards end:", sample_sets); + return update_stat_values(sample_sets); + }; show_hide_outliers = function() { var label; console.log("FOOBAR in beginning of show_hide_outliers"); diff --git a/wqflask/wqflask/static/new/javascript/show_trait_mapping_tools.coffee b/wqflask/wqflask/static/new/javascript/show_trait_mapping_tools.coffee index 3c995441..8571753e 100644 --- a/wqflask/wqflask/static/new/javascript/show_trait_mapping_tools.coffee +++ b/wqflask/wqflask/static/new/javascript/show_trait_mapping_tools.coffee @@ -52,6 +52,32 @@ $ -> ) return false + $("#interval_mapping_compute").click(() => + $("#progress_bar_container").modal() + url = "/interval_mapping" + form_data = $('#trait_data_form').serialize() + console.log("form_data is:", form_data) + $.ajax( + type: "POST" + url: url + data: form_data + error: (xhr, ajaxOptions, thrownError) => + alert("Sorry, an error occurred") + console.log(xhr) + clearInterval(this.my_timer) + $('#progress_bar_container').modal('hide') + $("body").html("We got an error.") + success: (data) => + clearInterval(this.my_timer) + $('#progress_bar_container').modal('hide') + $("body").html(data) + ) + console.log("settingInterval") + + this.my_timer = setInterval(get_progress, 1000) + return false + ) + $('#suggestive').hide() $('input[name=display_all]').change(() => diff --git a/wqflask/wqflask/static/new/javascript/show_trait_mapping_tools.js b/wqflask/wqflask/static/new/javascript/show_trait_mapping_tools.js index b309b167..1153b8ef 100644 --- a/wqflask/wqflask/static/new/javascript/show_trait_mapping_tools.js +++ b/wqflask/wqflask/static/new/javascript/show_trait_mapping_tools.js @@ -62,6 +62,33 @@ }); return false; }; + $("#interval_mapping_compute").click(function() { + var form_data, url; + $("#progress_bar_container").modal(); + url = "/interval_mapping"; + form_data = $('#trait_data_form').serialize(); + console.log("form_data is:", form_data); + $.ajax({ + type: "POST", + url: url, + data: form_data, + error: function(xhr, ajaxOptions, thrownError) { + alert("Sorry, an error occurred"); + console.log(xhr); + clearInterval(_this.my_timer); + $('#progress_bar_container').modal('hide'); + return $("body").html("We got an error."); + }, + success: function(data) { + clearInterval(_this.my_timer); + $('#progress_bar_container').modal('hide'); + return $("body").html(data); + } + }); + console.log("settingInterval"); + _this.my_timer = setInterval(get_progress, 1000); + return false; + }); $('#suggestive').hide(); $('input[name=display_all]').change(function() { console.log("check"); diff --git a/wqflask/wqflask/templates/show_trait.html b/wqflask/wqflask/templates/show_trait.html index 8a19e07b..91e6df42 100644 --- a/wqflask/wqflask/templates/show_trait.html +++ b/wqflask/wqflask/templates/show_trait.html @@ -56,6 +56,7 @@ + diff --git a/wqflask/wqflask/templates/show_trait_mapping_tools.html b/wqflask/wqflask/templates/show_trait_mapping_tools.html index c2d5211f..00301d39 100644 --- a/wqflask/wqflask/templates/show_trait_mapping_tools.html +++ b/wqflask/wqflask/templates/show_trait_mapping_tools.html @@ -30,7 +30,7 @@
- +
@@ -85,7 +85,8 @@
-
-
+
diff --git a/wqflask/wqflask/user_manager.py b/wqflask/wqflask/user_manager.py index 768415b5..1d0d9846 100644 --- a/wqflask/wqflask/user_manager.py +++ b/wqflask/wqflask/user_manager.py @@ -49,7 +49,8 @@ from utility import Bunch, Struct from base.data_set import create_datasets_list - +THREE_DAYS = 60 * 60 * 24 * 3 +#THREE_DAYS = 45 def timestamp(): return datetime.datetime.utcnow().isoformat() @@ -74,6 +75,27 @@ class UserSession(object): print("self.redis_key is:", self.redis_key) self.session_id = session_id self.record = Redis.hgetall(self.redis_key) + + + if not self.record: + # This will occur, for example, when the browser has been left open over a long + # weekend and the site hasn't been visited by the user + self.logged_in = False + + ########### Grrr...this won't work because of the way flask handles cookies + # Delete the cookie + #response = make_response(redirect(url_for('login'))) + #response.set_cookie(self.cookie_name, '', expires=0) + #flash( + # "Due to inactivity your session has expired. If you'd like please login again.") + #return response + return + + if Redis.ttl(self.redis_key) < THREE_DAYS: + # (Almost) everytime the user does something we extend the session_id in Redis... + print("Extending ttl...") + Redis.expire(self.redis_key, THREE_DAYS) + print("record is:", self.record) self.logged_in = True @@ -225,8 +247,8 @@ class VerificationEmail(object): ) Redis.set(key, data) - two_days = 60 * 60 * 24 * 2 - Redis.expire(key, two_days) + #two_days = 60 * 60 * 24 * 2 + Redis.expire(key, THREE_DAYS) to = user.email_address subject = self.subject body = render_template(self.template_name, @@ -415,7 +437,7 @@ class LoginUser(object): if self.remember_me: expire_time = self.remember_time else: - expire_time = 60 * 60 * 24 * 2 # two days + expire_time = THREE_DAYS Redis.expire(key, expire_time) db_session.add(login_rec) db_session.commit() diff --git a/wqflask/wqflask/views.py b/wqflask/wqflask/views.py index b2f08ca0..50161d41 100644 --- a/wqflask/wqflask/views.py +++ b/wqflask/wqflask/views.py @@ -32,7 +32,7 @@ from base.data_set import create_datasets_list from wqflask.show_trait import show_trait from wqflask.show_trait import export_trait_data from wqflask.marker_regression import marker_regression -#from wqflask.interval_mapping import interval_mapping +from wqflask.interval_mapping import interval_mapping from wqflask.correlation import show_corr_results from wqflask.correlation import corr_scatter_plot from utility import temp_data @@ -256,7 +256,11 @@ def interval_mapping_page(): wanted = ( 'trait_id', 'dataset', - 'suggestive' + 'chromosome', + 'num_permutations', + 'do_bootstraps', + 'default_control_locus', + 'control_locus' ) start_vars = {} @@ -308,10 +312,10 @@ def corr_scatter_plot_page(): indent=" ") return render_template("corr_scatter_plot.html", **template_vars.__dict__) -@app.route("/int_mapping", methods=('POST',)) -def interval_mapping_page(): - template_vars = interval_mapping.IntervalMapping(request.args) - return render_template("interval_mapping.html", **template_vars.__dict__) +#@app.route("/int_mapping", methods=('POST',)) +#def interval_mapping_page(): +# template_vars = interval_mapping.IntervalMapping(request.args) +# return render_template("interval_mapping.html", **template_vars.__dict__) # Todo: Can we simplify this? -Sam def sharing_info_page(): -- cgit v1.2.3 From e7142c0785a9680b56d789f1db0a738d6172de55 Mon Sep 17 00:00:00 2001 From: Zachary Sloan Date: Mon, 25 Nov 2013 22:53:46 +0000 Subject: Got the interval mapping results into a table --- wqflask/base/data_set.py | 12 +- wqflask/base/trait.py | 26 +- wqflask/wqflask/collect.py | 23 +- .../wqflask/interval_mapping/interval_mapping.py | 93 +++++-- .../wqflask/static/new/css/interval_mapping.css | 27 ++ .../wqflask/static/new/javascript/bar_chart.coffee | 7 +- wqflask/wqflask/static/new/javascript/bar_chart.js | 2 +- .../javascript/get_traits_from_collection.coffee | 15 ++ .../new/javascript/get_traits_from_collection.js | 20 ++ .../static/new/javascript/interval_mapping.coffee | 293 +++++++++++++++++++++ .../static/new/javascript/interval_mapping.js | 272 +++++++++++++++++++ .../static/new/javascript/scientific_notation.js | 13 + .../DataTables/js/dataTables.scientific.js | 13 + wqflask/wqflask/templates/base.html | 2 +- wqflask/wqflask/templates/collections/list.html | 11 +- wqflask/wqflask/templates/interval_mapping.html | 104 ++++++++ wqflask/wqflask/templates/show_trait.html | 1 + .../templates/show_trait_mapping_tools.html | 1 + wqflask/wqflask/views.py | 13 +- 19 files changed, 890 insertions(+), 58 deletions(-) create mode 100644 wqflask/wqflask/static/new/css/interval_mapping.css create mode 100644 wqflask/wqflask/static/new/javascript/get_traits_from_collection.coffee create mode 100644 wqflask/wqflask/static/new/javascript/get_traits_from_collection.js create mode 100644 wqflask/wqflask/static/new/javascript/interval_mapping.coffee create mode 100644 wqflask/wqflask/static/new/javascript/interval_mapping.js create mode 100644 wqflask/wqflask/static/new/javascript/scientific_notation.js create mode 100644 wqflask/wqflask/static/new/packages/DataTables/js/dataTables.scientific.js create mode 100644 wqflask/wqflask/templates/interval_mapping.html (limited to 'wqflask') diff --git a/wqflask/base/data_set.py b/wqflask/base/data_set.py index cd8c1ac1..8296adea 100755 --- a/wqflask/base/data_set.py +++ b/wqflask/base/data_set.py @@ -318,12 +318,17 @@ class DatasetGroup(object): #determine default genotype object if self.incparentsf1 and genotype_1.type != "intercross": - self.genotype = genotype_2 + #self.genotype = genotype_2 + genotype = genotype_2 else: self.incparentsf1 = 0 - self.genotype = genotype_1 + #self.genotype = genotype_1 + genotype = genotype_1 - self.samplelist = list(self.genotype.prgy) + #self.samplelist = list(self.genotype.prgy) + self.samplelist = list(genotype.prgy) + + return genotype #class DataSets(object): @@ -1084,6 +1089,7 @@ class MrnaAssayDataSet(DataSet): Strain.Name """ % (escape(trait), escape(self.name)) results = g.db.execute(query).fetchall() + print("RETRIEVED RESULTS HERE:", results) return results diff --git a/wqflask/base/trait.py b/wqflask/base/trait.py index 731f99eb..74bc07bb 100755 --- a/wqflask/base/trait.py +++ b/wqflask/base/trait.py @@ -154,7 +154,7 @@ class GeneralTrait(object): result.append(None) return result - def export_informative(self, incVar=0): + def export_informative(self, include_variance=0): """ export informative sample mostly used in qtl regression @@ -163,12 +163,12 @@ class GeneralTrait(object): samples = [] vals = [] the_vars = [] - for sample, value in self.data.items(): - if value.val != None: - if not incVar or value.var != None: - samples.append(sample) - vals.append(value.val) - the_vars.append(value.var) + for sample_name, sample_data in self.data.items(): + if sample_data.value != None: + if not include_variance or sample_data.variance != None: + samples.append(sample_name) + vals.append(sample_data.value) + the_vars.append(sample_data.variance) return samples, vals, the_vars @@ -235,11 +235,19 @@ class GeneralTrait(object): # Todo: is this necessary? If not remove self.data.clear() + if self.dataset.group.parlist: + all_samples_ordered = (self.dataset.group.parlist + + self.dataset.group.f1list + + self.dataset.group.samplelist) + elif self.dataset.group.f1list: + all_samples_ordered = self.dataset.group.f1list + self.dataset.group.samplelist + else: + all_samples_ordered = self.dataset.group.samplelist + if results: for item in results: - #name, value, variance, num_cases = item + name, value, variance, num_cases = item if not samplelist or (samplelist and name in samplelist): - name = item[0] self.data[name] = webqtlCaseData(*item) #name, value, variance, num_cases) #def keys(self): diff --git a/wqflask/wqflask/collect.py b/wqflask/wqflask/collect.py index ef7b37df..991d281c 100644 --- a/wqflask/wqflask/collect.py +++ b/wqflask/wqflask/collect.py @@ -23,7 +23,7 @@ Redis = redis.StrictRedis() from flask import (Flask, g, render_template, url_for, request, make_response, - redirect, flash) + redirect, flash, jsonify) from wqflask import app @@ -122,16 +122,18 @@ def create_new(): @app.route("/collections/list") def list_collections(): + params = request.args user_collections = g.user_session.user_ob.user_collections return render_template("collections/list.html", + params = params, user_collections = user_collections, ) - @app.route("/collections/view") def view_collection(): params = request.args + print("params in view collection:", params) uc_id = params['uc_id'] uc = model.UserCollection.query.get(uc_id) traits = json.loads(uc.members) @@ -139,6 +141,7 @@ def view_collection(): print("in view_collection traits are:", traits) trait_obs = [] + json_version = [] for atrait in traits: name, dataset_name = atrait.split(':') @@ -146,8 +149,16 @@ def view_collection(): trait_ob = trait.GeneralTrait(name=name, dataset_name=dataset_name) trait_ob.get_info() trait_obs.append(trait_ob) - - return render_template("collections/view.html", - trait_obs=trait_obs, - uc = uc, + + json_version.append(dict(name=trait_ob.name)) + #dis=trait_ob.description)) + + collection_info = dict(trait_obs=trait_obs, + uc = uc) + if "json" in params: + print("json_version:", json_version) + return json.dumps(json_version) + else: + return render_template("collections/view.html", + **collection_info ) diff --git a/wqflask/wqflask/interval_mapping/interval_mapping.py b/wqflask/wqflask/interval_mapping/interval_mapping.py index f41ebd2c..de7a2704 100755 --- a/wqflask/wqflask/interval_mapping/interval_mapping.py +++ b/wqflask/wqflask/interval_mapping/interval_mapping.py @@ -64,10 +64,12 @@ class IntervalMapping(object): for key in self.species.chromosomes.chromosomes.keys(): chromosome_mb_lengths[key] = self.species.chromosomes.chromosomes[key].mb_length + #print("self.qtl_results:", self.qtl_results) + self.js_data = dict( - lrs_lod = self.lrs_lod, chromosomes = chromosome_mb_lengths, qtl_results = self.qtl_results, + #lrs_lod = self.lrs_lod, ) def set_options(self, start_vars): @@ -76,10 +78,13 @@ class IntervalMapping(object): #self.plot_scale = start_vars['scale'] #if self.plotScale == 'physic' and not fd.genotype.Mbmap: # self.plotScale = 'morgan' - self.num_permutations = start_vars['num_permutations'] + self.num_permutations = int(start_vars['num_permutations']) #self.do_bootstrap = start_vars['do_bootstrap'] - #self.control_locus = start_vars['control_locus'] self.selected_chr = start_vars['chromosome'] + if 'control_locus' in start_vars: + self.control_locus = start_vars['control_locus'] + else: + self.control_locus = None #self.weighted_regression = start_vars['weighted'] #self.lrs_lod = start_vars['lrs_lod'] @@ -88,40 +93,76 @@ class IntervalMapping(object): """Generates qtl results for plotting interval map""" self.dataset.group.get_markers() - self.dataset.group.read_genotype_file() + genotype = self.dataset.group.read_genotype_file() samples, values, variances = self.this_trait.export_informative() + + trimmed_samples = [] + trimmed_values = [] + for i in range(0, len(samples)): + if samples[i] in self.dataset.group.samplelist: + trimmed_samples.append(samples[i]) + trimmed_values.append(values[i]) + + #if self.weighted_regression: + # self.lrs_array = self.genotype.permutation(strains = trimmed_samples, + # trait = trimmed_values, + # variance = _vars, + # nperm=self.num_permutations) + #else: + self.lrs_array = genotype.permutation(strains = trimmed_samples, + trait = trimmed_values, + nperm= self.num_permutations) + self.suggestive = self.lrs_array[int(self.num_permutations*0.37-1)] + self.significant = self.lrs_array[int(self.num_permutations*0.95-1)] + + print("samples:", trimmed_samples) + if self.control_locus: - if self.weighted_regression: - self.qtl_results = self.dataset.genotype.regression(strains = samples, - trait = values, - variance = variances, - control = self.control_locus) - else: - self.qtl_results = self.dataset.genotype.regression(strains = samples, - trait = values, - control = self.control_locus) + #if self.weighted_regression: + # self.qtl_results = self.dataset.genotype.regression(strains = samples, + # trait = values, + # variance = variances, + # control = self.control_locus) + #else: + #reaper_results = self.dataset.group.genotype.regression(strains = trimmed_samples, + # trait = trimmed_values, + # control = self.control_locus) + reaper_results = genotype.regression(strains = trimmed_samples, + trait = trimmed_values, + control = self.control_locus) else: - if self.weighted_regression: - self.qtl_results = self.dataset.genotype.regression(strains = samples, - trait = values, - variance = variances) - else: - self.qtl_results = self.dataset.genotype.regression(strains = samples, - trait = values) + #if self.weighted_regression: + # self.qtl_results = self.dataset.genotype.regression(strains = samples, + # trait = values, + # variance = variances) + #else: + print("strains:", trimmed_samples) + print("trait:", trimmed_values) + #reaper_results = self.dataset.group.genotype.regression(strains = trimmed_samples, + # trait = trimmed_values) + reaper_results = genotype.regression(strains = trimmed_samples, + trait = trimmed_values) + #Need to convert the QTL objects that qtl reaper returns into a json serializable dictionary + self.qtl_results = [] + for qtl in reaper_results: + reaper_locus = qtl.locus + locus = {"name":reaper_locus.name, "chr":reaper_locus.chr, "cM":reaper_locus.cM, "Mb":reaper_locus.Mb} + qtl = {"lrs": qtl.lrs, "locus": locus, "additive": qtl.additive} + self.qtl_results.append(qtl) #pheno_vector = np.array([val == "x" and np.nan or float(val) for val in self.vals]) #if self.dataset.group.species == "human": # p_values, t_stats = self.gen_human_results(pheno_vector, tempdata) #else: - genotype_data = [marker['genotypes'] for marker in self.dataset.group.markers.markers] - - no_val_samples = self.identify_empty_samples() - trimmed_genotype_data = self.trim_genotypes(genotype_data, no_val_samples) - - genotype_matrix = np.array(trimmed_genotype_data).T + #genotype_data = [marker['genotypes'] for marker in self.dataset.group.markers.markers] + # + #no_val_samples = self.identify_empty_samples() + #trimmed_genotype_data = self.trim_genotypes(genotype_data, no_val_samples) + # + #genotype_matrix = np.array(trimmed_genotype_data).T #t_stats, p_values = lmm.run( # pheno_vector, diff --git a/wqflask/wqflask/static/new/css/interval_mapping.css b/wqflask/wqflask/static/new/css/interval_mapping.css new file mode 100644 index 00000000..9d23ba25 --- /dev/null +++ b/wqflask/wqflask/static/new/css/interval_mapping.css @@ -0,0 +1,27 @@ +.manhattan_plot .y_axis path, +.manhattan_plot .y_axis line { + fill: none; + stroke: black; + shape-rendering: crispEdges; +} +.manhattan_plot .y_axis text { + font-family: sans-serif; + font-size: 14px; +} + +.manhattan_plot .x_axis path, +.manhattan_plot .x_axis line { + fill: none; + stroke: black; + shape-rendering: crispEdges; +} +.manhattan_plot .x_axis text { + text-anchor: end; + font-family: sans-serif; + font-size: 8px; +} + +rect { + stroke: WhiteSmoke; + fill: lightgrey; +} \ No newline at end of file diff --git a/wqflask/wqflask/static/new/javascript/bar_chart.coffee b/wqflask/wqflask/static/new/javascript/bar_chart.coffee index 2c60d3ab..4921b55e 100644 --- a/wqflask/wqflask/static/new/javascript/bar_chart.coffee +++ b/wqflask/wqflask/static/new/javascript/bar_chart.coffee @@ -276,7 +276,7 @@ class Bar_Chart .attr("height", 100) .attr("width", 100) .attr('transform', 'translate(-20,50)') - + legend_rect = legend.selectAll('rect') .data(distinct_vals) .enter() @@ -305,13 +305,12 @@ class Bar_Chart ) color_by_trait: () -> - $('#collections_holder').load('/collections/list #collections_list', => + $('#collections_holder').load('/collections/list?color_by_trait #collections_list', => $.colorbox( inline: true href: "#collections_holder" ) ) - - + root.Bar_Chart = Bar_Chart \ No newline at end of file diff --git a/wqflask/wqflask/static/new/javascript/bar_chart.js b/wqflask/wqflask/static/new/javascript/bar_chart.js index 03902741..9c2059c0 100644 --- a/wqflask/wqflask/static/new/javascript/bar_chart.js +++ b/wqflask/wqflask/static/new/javascript/bar_chart.js @@ -322,7 +322,7 @@ Bar_Chart.prototype.color_by_trait = function() { var _this = this; - return $('#collections_holder').load('/collections/list #collections_list', function() { + return $('#collections_holder').load('/collections/list?color_by_trait #collections_list', function() { return $.colorbox({ inline: true, href: "#collections_holder" diff --git a/wqflask/wqflask/static/new/javascript/get_traits_from_collection.coffee b/wqflask/wqflask/static/new/javascript/get_traits_from_collection.coffee new file mode 100644 index 00000000..6854dda5 --- /dev/null +++ b/wqflask/wqflask/static/new/javascript/get_traits_from_collection.coffee @@ -0,0 +1,15 @@ + +console.log("before get_traits_from_collection") + + +collection_hover = () -> + console.log("Hovering over:", $(this)) + this_collection_url = $(this).find('.collection_name').prop("href") + this_collection_url += "&json" + console.log("this_collection_url", this_collection_url) + +$ -> + console.log("inside get_traits_from_collection") + $(document).on("mouseover", ".collection_line", collection_hover) + + \ No newline at end of file diff --git a/wqflask/wqflask/static/new/javascript/get_traits_from_collection.js b/wqflask/wqflask/static/new/javascript/get_traits_from_collection.js new file mode 100644 index 00000000..9ef31088 --- /dev/null +++ b/wqflask/wqflask/static/new/javascript/get_traits_from_collection.js @@ -0,0 +1,20 @@ +// Generated by CoffeeScript 1.6.1 +(function() { + var collection_hover; + + console.log("before get_traits_from_collection"); + + collection_hover = function() { + var this_collection_url; + console.log("Hovering over:", $(this)); + this_collection_url = $(this).find('.collection_name').prop("href"); + this_collection_url += "&json"; + return console.log("this_collection_url", this_collection_url); + }; + + $(function() { + console.log("inside get_traits_from_collection"); + return $(document).on("mouseover", ".collection_line", collection_hover); + }); + +}).call(this); diff --git a/wqflask/wqflask/static/new/javascript/interval_mapping.coffee b/wqflask/wqflask/static/new/javascript/interval_mapping.coffee new file mode 100644 index 00000000..78265f27 --- /dev/null +++ b/wqflask/wqflask/static/new/javascript/interval_mapping.coffee @@ -0,0 +1,293 @@ +$ -> + + class Interval_Map + constructor: (@plot_height, @plot_width) -> + @qtl_results = js_data.qtl_results + console.log("qtl_results are:", @qtl_results) + @chromosomes = js_data.chromosomes + + @total_length = 0 + + @max_chr = @get_max_chr() + + @x_coords = [] + @y_coords = [] + @marker_names = [] + console.time('Create coordinates') + @create_coordinates() + console.log("@x_coords: ", @x_coords) + console.log("@y_coords: ", @y_coords) + console.timeEnd('Create coordinates') + [@chr_lengths, @cumulative_chr_lengths] = @get_chr_lengths() + + # Buffer to allow for the ticks/labels to be drawn + @x_buffer = @plot_width/30 + @y_buffer = @plot_height/20 + + #@x_max = d3.max(@x_coords) + @x_max = @total_length + console.log("@x_max: ", @x_max) + console.log("@x_buffer: ", @x_buffer) + @y_max = d3.max(@y_coords) * 1.2 + + @svg = @create_svg() + @plot_coordinates = _.zip(@x_coords, @y_coords, @marker_names) + + @plot_height -= @y_buffer + @create_scales() + console.time('Create graph') + @create_graph() + console.timeEnd('Create graph') + + get_max_chr: () -> + max_chr = 0 + for result in @qtl_results + chr = parseInt(result.chr) + if not _.isNaN(chr) + if chr > max_chr + max_chr = chr + return max_chr + + get_chr_lengths: () -> + ### + #Gets a list of both individual and cumulative (the position of one on the graph + #is its own length plus the lengths of all preceding chromosomes) lengths in order + #to draw the vertical lines separating chromosomes and the chromosome labels + # + ### + + console.log("@chromosomes: ", @chromosomes) + + cumulative_chr_lengths = [] + chr_lengths = [] + total_length = 0 + for key of @chromosomes + this_length = @chromosomes[key] + chr_lengths.push(this_length) + cumulative_chr_lengths.push(total_length + this_length) + total_length += this_length + + console.log("chr_lengths: ", chr_lengths) + + return [chr_lengths, cumulative_chr_lengths] + + create_coordinates: () -> + chr_lengths = [] + chr_seen = [] + for result in js_data.qtl_results + if result.locus.chr == "X" + chr_length = parseFloat(@chromosomes[20]) + else + chr_length = parseFloat(@chromosomes[result.locus.chr]) + if not(result.locus.chr in chr_seen) + chr_seen.push(result.locus.chr) + chr_lengths.push(chr_length) + if result.locus.chr != "1" + @total_length += parseFloat(chr_lengths[chr_lengths.length - 2]) + @x_coords.push(@total_length + parseFloat(result.locus.Mb)) + @y_coords.push(result.lrs) + @marker_names.push(result.locus.name) + @total_length += parseFloat(chr_lengths[chr_lengths.length-1]) + #console.log("chr_lengths: ", chr_lengths) + + create_svg: () -> + svg = d3.select("#interval_map") + .append("svg") + .attr("class", "interval_map") + .attr("width", @plot_width+@x_buffer) + .attr("height", @plot_height+@y_buffer) + + return svg + + create_graph: () -> + @add_border() + @add_x_axis() + @add_y_axis() + @add_chr_lines() + @fill_chr_areas() + @add_chr_labels() + @connect_markers() + + add_border: () -> + border_coords = [[@y_buffer, @plot_height, @x_buffer, @x_buffer], + [@y_buffer, @plot_height, @plot_width, @plot_width], + [@y_buffer, @y_buffer, @x_buffer, @plot_width], + [@plot_height, @plot_height, @x_buffer, @plot_width]] + + @svg.selectAll("line") + .data(border_coords) + .enter() + .append("line") + .attr("y1", (d) => + return d[0] + ) + .attr("y2", (d) => + return d[1] + ) + .attr("x1", (d) => + return d[2] + ) + .attr("x2", (d) => + return d[3] + ) + .style("stroke", "#000") + + create_scales: () -> + @x_scale = d3.scale.linear() + .domain([0, d3.max(@x_coords)]) + .range([@x_buffer, @plot_width]) + + @y_scale = d3.scale.linear() + .domain([0, @y_max]) + .range([@plot_height, @y_buffer]) + + create_x_axis_tick_values: () -> + tick_vals = [] + for val in [25..@cumulative_chr_lengths[0]] when val%25 == 0 + tick_vals.push(val) + + for length, i in @cumulative_chr_lengths + if i == 0 + continue + chr_ticks = [] + tick_count = Math.floor(@chr_lengths[i]/25) + tick_val = parseInt(@cumulative_chr_lengths[i-1]) + for tick in [0..(tick_count-1)] + tick_val += 25 + chr_ticks.push(tick_val) + Array::push.apply tick_vals, chr_ticks + + #console.log("tick_vals:", tick_vals) + return tick_vals + + add_x_axis: () -> + xAxis = d3.svg.axis() + .scale(@x_scale) + .orient("bottom") + .tickValues(@create_x_axis_tick_values()) + + next_chr = 1 + tmp_tick_val = 0 + xAxis.tickFormat((d) => + d3.format("d") #format as integer + if d < @cumulative_chr_lengths[0] + tick_val = d + else + next_chr_length = @cumulative_chr_lengths[next_chr] + if d > next_chr_length + next_chr += 1 + tmp_tick_val = 25 + tick_val = tmp_tick_val + else + tmp_tick_val += 25 + tick_val = tmp_tick_val + return (tick_val) + ) + + @svg.append("g") + .attr("class", "x_axis") + .attr("transform", "translate(0," + @plot_height + ")") + .call(xAxis) + .selectAll("text") + .attr("text-anchor", "right") + .attr("dx", "-1.6em") + .attr("transform", (d) => + return "translate(-12,0) rotate(-90)" + ) + #.attr("dy", "-1.0em") + + + add_y_axis: () -> + yAxis = d3.svg.axis() + .scale(@y_scale) + .orient("left") + .ticks(5) + + @svg.append("g") + .attr("class", "y_axis") + .attr("transform", "translate(" + @x_buffer + ",0)") + .call(yAxis) + + add_chr_lines: () -> + @svg.selectAll("line") + .data(@cumulative_chr_lengths, (d) => + return d + ) + .enter() + .append("line") + .attr("x1", @x_scale) + .attr("x2", @x_scale) + .attr("y1", @y_buffer) + .attr("y2", @plot_height) + .style("stroke", "#ccc") + + fill_chr_areas: () -> + @svg.selectAll("rect.chr_fill_area_1") + .data(_.zip(@chr_lengths, @cumulative_chr_lengths), (d) => + return d + ) + .enter() + .append("rect") + .attr("class", "chr_fill_area_1") + .attr("x", (d, i) => + if i == 0 + return @x_scale(0) + else + return @x_scale(@cumulative_chr_lengths[i-1]) + ) + .attr("y", @y_buffer) + .attr("width", (d) => + return @x_scale(d[0]) + ) + .attr("height", @plot_height-@y_buffer) + + add_chr_labels: () -> + chr_names = [] + for key of @chromosomes + chr_names.push(key) + chr_info = _.zip(chr_names, @chr_lengths, @cumulative_chr_lengths) + @svg.selectAll("text") + .data(chr_info, (d) => + return d + ) + .enter() + .append("text") + .text((d) => + return d[0] + ) + .attr("x", (d) => + return @x_scale(d[2] - d[1]/2) + ) + .attr("y", @plot_height * 0.1) + .attr("dx", "0em") + .attr("text-anchor", "middle") + .attr("font-family", "sans-serif") + .attr("font-size", "18px") + .attr("fill", "grey") + + connect_markers: () -> + @svg.selectAll("path") + .data(@plot_coordinates) + .enter() + .attr("x1", (d, i) => + if i == 0 + return @x_buffer + else + return parseFloat(@x_buffer) + ((parseFloat(@plot_width)-parseFloat(@x_buffer)) * @plot_coordinates[i-1][0]/parseFloat(@x_max)) + ) + .attr("y1", (d, i) => + if i == 0 + return @plot_height + else + return @plot_height - ((@plot_height-@y_buffer) * @plot_coordinates[i-1][1]/@y_max) + ) + .attr("x2", (d) => + return parseFloat(@x_buffer) + ((parseFloat(@plot_width)-parseFloat(@x_buffer)) * d[0]/parseFloat(@x_max)) + ) + .attr("y2", (d) => + return @plot_height - ((@plot_height-@y_buffer) * d[1]/@y_max) + ) + + console.time('Create manhattan plot') + new Interval_Map(600, 1200) + console.timeEnd('Create manhattan plot') \ No newline at end of file diff --git a/wqflask/wqflask/static/new/javascript/interval_mapping.js b/wqflask/wqflask/static/new/javascript/interval_mapping.js new file mode 100644 index 00000000..5ae8ffab --- /dev/null +++ b/wqflask/wqflask/static/new/javascript/interval_mapping.js @@ -0,0 +1,272 @@ +// Generated by CoffeeScript 1.6.1 +(function() { + var __indexOf = [].indexOf || function(item) { for (var i = 0, l = this.length; i < l; i++) { if (i in this && this[i] === item) return i; } return -1; }; + + $(function() { + var Interval_Map; + Interval_Map = (function() { + + function Interval_Map(plot_height, plot_width) { + var _ref; + this.plot_height = plot_height; + this.plot_width = plot_width; + this.qtl_results = js_data.qtl_results; + console.log("qtl_results are:", this.qtl_results); + this.chromosomes = js_data.chromosomes; + this.total_length = 0; + this.max_chr = this.get_max_chr(); + this.x_coords = []; + this.y_coords = []; + this.marker_names = []; + console.time('Create coordinates'); + this.create_coordinates(); + console.log("@x_coords: ", this.x_coords); + console.log("@y_coords: ", this.y_coords); + console.timeEnd('Create coordinates'); + _ref = this.get_chr_lengths(), this.chr_lengths = _ref[0], this.cumulative_chr_lengths = _ref[1]; + this.x_buffer = this.plot_width / 30; + this.y_buffer = this.plot_height / 20; + this.x_max = this.total_length; + console.log("@x_max: ", this.x_max); + console.log("@x_buffer: ", this.x_buffer); + this.y_max = d3.max(this.y_coords) * 1.2; + this.svg = this.create_svg(); + this.plot_coordinates = _.zip(this.x_coords, this.y_coords, this.marker_names); + this.plot_height -= this.y_buffer; + this.create_scales(); + console.time('Create graph'); + this.create_graph(); + console.timeEnd('Create graph'); + } + + Interval_Map.prototype.get_max_chr = function() { + var chr, max_chr, result, _i, _len, _ref; + max_chr = 0; + _ref = this.qtl_results; + for (_i = 0, _len = _ref.length; _i < _len; _i++) { + result = _ref[_i]; + chr = parseInt(result.chr); + if (!_.isNaN(chr)) { + if (chr > max_chr) { + max_chr = chr; + } + } + } + return max_chr; + }; + + Interval_Map.prototype.get_chr_lengths = function() { + /* + #Gets a list of both individual and cumulative (the position of one on the graph + #is its own length plus the lengths of all preceding chromosomes) lengths in order + #to draw the vertical lines separating chromosomes and the chromosome labels + # + */ + + var chr_lengths, cumulative_chr_lengths, key, this_length, total_length; + console.log("@chromosomes: ", this.chromosomes); + cumulative_chr_lengths = []; + chr_lengths = []; + total_length = 0; + for (key in this.chromosomes) { + this_length = this.chromosomes[key]; + chr_lengths.push(this_length); + cumulative_chr_lengths.push(total_length + this_length); + total_length += this_length; + } + console.log("chr_lengths: ", chr_lengths); + return [chr_lengths, cumulative_chr_lengths]; + }; + + Interval_Map.prototype.create_coordinates = function() { + var chr_length, chr_lengths, chr_seen, result, _i, _len, _ref, _ref1; + chr_lengths = []; + chr_seen = []; + _ref = js_data.qtl_results; + for (_i = 0, _len = _ref.length; _i < _len; _i++) { + result = _ref[_i]; + if (result.locus.chr === "X") { + chr_length = parseFloat(this.chromosomes[20]); + } else { + chr_length = parseFloat(this.chromosomes[result.locus.chr]); + } + if (!(_ref1 = result.locus.chr, __indexOf.call(chr_seen, _ref1) >= 0)) { + chr_seen.push(result.locus.chr); + chr_lengths.push(chr_length); + if (result.locus.chr !== "1") { + this.total_length += parseFloat(chr_lengths[chr_lengths.length - 2]); + } + } + this.x_coords.push(this.total_length + parseFloat(result.locus.Mb)); + this.y_coords.push(result.lrs); + this.marker_names.push(result.locus.name); + } + return this.total_length += parseFloat(chr_lengths[chr_lengths.length - 1]); + }; + + Interval_Map.prototype.create_svg = function() { + var svg; + svg = d3.select("#interval_map").append("svg").attr("class", "interval_map").attr("width", this.plot_width + this.x_buffer).attr("height", this.plot_height + this.y_buffer); + return svg; + }; + + Interval_Map.prototype.create_graph = function() { + this.add_border(); + this.add_x_axis(); + this.add_y_axis(); + this.add_chr_lines(); + this.fill_chr_areas(); + this.add_chr_labels(); + return this.connect_markers(); + }; + + Interval_Map.prototype.add_border = function() { + var border_coords, + _this = this; + border_coords = [[this.y_buffer, this.plot_height, this.x_buffer, this.x_buffer], [this.y_buffer, this.plot_height, this.plot_width, this.plot_width], [this.y_buffer, this.y_buffer, this.x_buffer, this.plot_width], [this.plot_height, this.plot_height, this.x_buffer, this.plot_width]]; + return this.svg.selectAll("line").data(border_coords).enter().append("line").attr("y1", function(d) { + return d[0]; + }).attr("y2", function(d) { + return d[1]; + }).attr("x1", function(d) { + return d[2]; + }).attr("x2", function(d) { + return d[3]; + }).style("stroke", "#000"); + }; + + Interval_Map.prototype.create_scales = function() { + this.x_scale = d3.scale.linear().domain([0, d3.max(this.x_coords)]).range([this.x_buffer, this.plot_width]); + return this.y_scale = d3.scale.linear().domain([0, this.y_max]).range([this.plot_height, this.y_buffer]); + }; + + Interval_Map.prototype.create_x_axis_tick_values = function() { + var chr_ticks, i, length, tick, tick_count, tick_val, tick_vals, val, _i, _j, _k, _len, _ref, _ref1, _ref2; + tick_vals = []; + for (val = _i = 25, _ref = this.cumulative_chr_lengths[0]; 25 <= _ref ? _i <= _ref : _i >= _ref; val = 25 <= _ref ? ++_i : --_i) { + if (val % 25 === 0) { + tick_vals.push(val); + } + } + _ref1 = this.cumulative_chr_lengths; + for (i = _j = 0, _len = _ref1.length; _j < _len; i = ++_j) { + length = _ref1[i]; + if (i === 0) { + continue; + } + chr_ticks = []; + tick_count = Math.floor(this.chr_lengths[i] / 25); + tick_val = parseInt(this.cumulative_chr_lengths[i - 1]); + for (tick = _k = 0, _ref2 = tick_count - 1; 0 <= _ref2 ? _k <= _ref2 : _k >= _ref2; tick = 0 <= _ref2 ? ++_k : --_k) { + tick_val += 25; + chr_ticks.push(tick_val); + } + Array.prototype.push.apply(tick_vals, chr_ticks); + } + return tick_vals; + }; + + Interval_Map.prototype.add_x_axis = function() { + var next_chr, tmp_tick_val, xAxis, + _this = this; + xAxis = d3.svg.axis().scale(this.x_scale).orient("bottom").tickValues(this.create_x_axis_tick_values()); + next_chr = 1; + tmp_tick_val = 0; + xAxis.tickFormat(function(d) { + var next_chr_length, tick_val; + d3.format("d"); + if (d < _this.cumulative_chr_lengths[0]) { + tick_val = d; + } else { + next_chr_length = _this.cumulative_chr_lengths[next_chr]; + if (d > next_chr_length) { + next_chr += 1; + tmp_tick_val = 25; + tick_val = tmp_tick_val; + } else { + tmp_tick_val += 25; + tick_val = tmp_tick_val; + } + } + return tick_val; + }); + return this.svg.append("g").attr("class", "x_axis").attr("transform", "translate(0," + this.plot_height + ")").call(xAxis).selectAll("text").attr("text-anchor", "right").attr("dx", "-1.6em").attr("transform", function(d) { + return "translate(-12,0) rotate(-90)"; + }); + }; + + Interval_Map.prototype.add_y_axis = function() { + var yAxis; + yAxis = d3.svg.axis().scale(this.y_scale).orient("left").ticks(5); + return this.svg.append("g").attr("class", "y_axis").attr("transform", "translate(" + this.x_buffer + ",0)").call(yAxis); + }; + + Interval_Map.prototype.add_chr_lines = function() { + var _this = this; + return this.svg.selectAll("line").data(this.cumulative_chr_lengths, function(d) { + return d; + }).enter().append("line").attr("x1", this.x_scale).attr("x2", this.x_scale).attr("y1", this.y_buffer).attr("y2", this.plot_height).style("stroke", "#ccc"); + }; + + Interval_Map.prototype.fill_chr_areas = function() { + var _this = this; + return this.svg.selectAll("rect.chr_fill_area_1").data(_.zip(this.chr_lengths, this.cumulative_chr_lengths), function(d) { + return d; + }).enter().append("rect").attr("class", "chr_fill_area_1").attr("x", function(d, i) { + if (i === 0) { + return _this.x_scale(0); + } else { + return _this.x_scale(_this.cumulative_chr_lengths[i - 1]); + } + }).attr("y", this.y_buffer).attr("width", function(d) { + return _this.x_scale(d[0]); + }).attr("height", this.plot_height - this.y_buffer); + }; + + Interval_Map.prototype.add_chr_labels = function() { + var chr_info, chr_names, key, + _this = this; + chr_names = []; + for (key in this.chromosomes) { + chr_names.push(key); + } + chr_info = _.zip(chr_names, this.chr_lengths, this.cumulative_chr_lengths); + return this.svg.selectAll("text").data(chr_info, function(d) { + return d; + }).enter().append("text").text(function(d) { + return d[0]; + }).attr("x", function(d) { + return _this.x_scale(d[2] - d[1] / 2); + }).attr("y", this.plot_height * 0.1).attr("dx", "0em").attr("text-anchor", "middle").attr("font-family", "sans-serif").attr("font-size", "18px").attr("fill", "grey"); + }; + + Interval_Map.prototype.connect_markers = function() { + var _this = this; + return this.svg.selectAll("path").data(this.plot_coordinates).enter().attr("x1", function(d, i) { + if (i === 0) { + return _this.x_buffer; + } else { + return parseFloat(_this.x_buffer) + ((parseFloat(_this.plot_width) - parseFloat(_this.x_buffer)) * _this.plot_coordinates[i - 1][0] / parseFloat(_this.x_max)); + } + }).attr("y1", function(d, i) { + if (i === 0) { + return _this.plot_height; + } else { + return _this.plot_height - ((_this.plot_height - _this.y_buffer) * _this.plot_coordinates[i - 1][1] / _this.y_max); + } + }).attr("x2", function(d) { + return parseFloat(_this.x_buffer) + ((parseFloat(_this.plot_width) - parseFloat(_this.x_buffer)) * d[0] / parseFloat(_this.x_max)); + }).attr("y2", function(d) { + return _this.plot_height - ((_this.plot_height - _this.y_buffer) * d[1] / _this.y_max); + }); + }; + + return Interval_Map; + + })(); + console.time('Create manhattan plot'); + new Interval_Map(600, 1200); + return console.timeEnd('Create manhattan plot'); + }); + +}).call(this); diff --git a/wqflask/wqflask/static/new/javascript/scientific_notation.js b/wqflask/wqflask/static/new/javascript/scientific_notation.js new file mode 100644 index 00000000..82c55fda --- /dev/null +++ b/wqflask/wqflask/static/new/javascript/scientific_notation.js @@ -0,0 +1,13 @@ +jQuery.extend( jQuery.fn.dataTableExt.oSort, { + "scientific-pre": function ( a ) { + return parseFloat(a); + }, + + "scientific-asc": function ( a, b ) { + return ((a < b) ? -1 : ((a > b) ? 1 : 0)); + }, + + "scientific-desc": function ( a, b ) { + return ((a < b) ? 1 : ((a > b) ? -1 : 0)); + } +} ); \ No newline at end of file diff --git a/wqflask/wqflask/static/new/packages/DataTables/js/dataTables.scientific.js b/wqflask/wqflask/static/new/packages/DataTables/js/dataTables.scientific.js new file mode 100644 index 00000000..82c55fda --- /dev/null +++ b/wqflask/wqflask/static/new/packages/DataTables/js/dataTables.scientific.js @@ -0,0 +1,13 @@ +jQuery.extend( jQuery.fn.dataTableExt.oSort, { + "scientific-pre": function ( a ) { + return parseFloat(a); + }, + + "scientific-asc": function ( a, b ) { + return ((a < b) ? -1 : ((a > b) ? 1 : 0)); + }, + + "scientific-desc": function ( a, b ) { + return ((a < b) ? 1 : ((a > b) ? -1 : 0)); + } +} ); \ No newline at end of file diff --git a/wqflask/wqflask/templates/base.html b/wqflask/wqflask/templates/base.html index ea6db646..9b98c955 100644 --- a/wqflask/wqflask/templates/base.html +++ b/wqflask/wqflask/templates/base.html @@ -198,7 +198,7 @@
- + + {# endif #} +
@@ -41,10 +46,8 @@ {% endblock %} {% block js %} - - {% endblock %} diff --git a/wqflask/wqflask/templates/interval_mapping.html b/wqflask/wqflask/templates/interval_mapping.html new file mode 100644 index 00000000..25de2dc1 --- /dev/null +++ b/wqflask/wqflask/templates/interval_mapping.html @@ -0,0 +1,104 @@ +{% extends "base.html" %} +{% block title %}Interval Mapping{% endblock %} +{% block css %} + + + + + +{% endblock %} +{% block content %} + + {{ header("Mapping", + '{}: {}'.format(this_trait.name, this_trait.description_fmt)) }} + +
+
+

+ Whole Genome Mapping +

+
+
+ +
+
+

+ Results +

+
+ + + + + + + + + + + + + {% for marker in qtl_results %} + + + + + + + + + {% endfor %} + +
IndexLRS ScoreAdditive EffectChrMbLocus
{{ loop.index }}{{ marker.lrs|float }}{{ marker.additive|float }}{{ marker.locus.chr|int }}{{ marker.locus.Mb|float }}{{ marker.locus.name }}
+ +
+ + + +{% endblock %} + +{% block js %} + + + + + + + + + + + + + + +{% endblock %} \ No newline at end of file diff --git a/wqflask/wqflask/templates/show_trait.html b/wqflask/wqflask/templates/show_trait.html index 91e6df42..ec729e1c 100644 --- a/wqflask/wqflask/templates/show_trait.html +++ b/wqflask/wqflask/templates/show_trait.html @@ -57,6 +57,7 @@ + diff --git a/wqflask/wqflask/templates/show_trait_mapping_tools.html b/wqflask/wqflask/templates/show_trait_mapping_tools.html index 00301d39..a835a41b 100644 --- a/wqflask/wqflask/templates/show_trait_mapping_tools.html +++ b/wqflask/wqflask/templates/show_trait_mapping_tools.html @@ -20,6 +20,7 @@