From ea46f42ee640928b92947bfb204c41a482d80937 Mon Sep 17 00:00:00 2001
From: root
Date: Tue, 8 May 2012 18:39:56 -0500
Subject: Add all the source codes into the github.
---
web/tutorial/ppt/WebQTLDemo_files/slide0048.htm | 897 ++++++++++++++++++++++++
1 file changed, 897 insertions(+)
create mode 100755 web/tutorial/ppt/WebQTLDemo_files/slide0048.htm
(limited to 'web/tutorial/ppt/WebQTLDemo_files/slide0048.htm')
diff --git a/web/tutorial/ppt/WebQTLDemo_files/slide0048.htm b/web/tutorial/ppt/WebQTLDemo_files/slide0048.htm
new file mode 100755
index 00000000..53a7011d
--- /dev/null
+++ b/web/tutorial/ppt/WebQTLDemo_files/slide0048.htm
@@ -0,0 +1,897 @@
+
PowerPoint Presentation - Complex trait analysis, develop-ment, and
genomics
+
How to make recombinant inbred strains (RI)
C57BL/6J
(B)
DBA/2J
(D)
F1
20 generations brother-sister matings
BXD1
BXD2
BXD80
+ É +
F2
BXD RI
Strain set
fully
inbred
isogenic
hetero-
geneous
Recombined chromosomes are needed for mapping
female
male
chromosome
pair
Inbred
Isogenic
siblings
BXD
+
The next set of slides
provide a very short interlude on QTL mapping. You will need to do some
independent reading on this topic if this is your first exposure to QTL
mapping. The recombinant inbred strains that we are using in WebQTL and in
this particular demo were generated about 25 years ago by Dr. Ben Taylor at
The Jackson Laboratory. He crossed a female C57BL/6J mouse with a male
DBA/2J mice. At the bottom of this slide we have schematized one chromosome
pair from three out of 80 BXD RI strains.The dashed vertical lines that lead to the final BXD RI
lines involve 20 full sib matings (about 6 years of breeding). Some lines
dieout during inbreeding. For
example, there is no extant BXD3 or BXD4 strain.