PowerPoint Presentation - Complex trait analysis, develop-ment, and genomics

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WebQTL
link to
www.webqtl.org/search.html

1.Discovering shared expression patterns

2.Discovering upstream modulators (QTLs)

3.Discovering downstream targets

RNA

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	Part 2: Mapping upstream modulators or QTLs. A quantitative trait locus is a chromosomal region that harbors one or a few polymorphic gene loci that influence a trait. We are going to be looking for QTLs that modulate the steady state expression level of App in the adult mouse forebrain.