From ea46f42ee640928b92947bfb204c41a482d80937 Mon Sep 17 00:00:00 2001
From: root
Date: Tue, 8 May 2012 18:39:56 -0500
Subject: Add all the source codes into the github.
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PowerPoint Presentation - Complex trait analysis, develop-ment, and
genomics
WebQTL link
to www.webqtl.org/search.html
1.Discovering shared expression patterns
2.Discovering upstream modulators (QTLs)
3.Discovering downstream targets
Part 3.Many investigators would like to
discover the set of downstream targets of a gene of interest.
In a genetic and
functional sense, that question can only be addressed effectively if there is
genetic variation in the particular gene.We know that Fos is an important transcription factor, but
unless it is polymorphic between C57BL/6J and DBA/2J, then it cannot generate
a genetic variance signal with which we can work. We can still study
covariance of Fos and hundreds of other transcripts (an interesting
exercise), but there are no genetic causes-and-effects.