From d0911a04958a04042da02a334ccc528dae79cc17 Mon Sep 17 00:00:00 2001 From: zsloan Date: Fri, 27 Mar 2015 20:28:51 +0000 Subject: Removed everything from 'web' directory except genofiles and renamed the directory to 'genotype_files' --- web/dbdoc/STSPL_1107_R.html | 131 -------------------------------------------- 1 file changed, 131 deletions(-) delete mode 100755 web/dbdoc/STSPL_1107_R.html (limited to 'web/dbdoc/STSPL_1107_R.html') diff --git a/web/dbdoc/STSPL_1107_R.html b/web/dbdoc/STSPL_1107_R.html deleted file mode 100755 index 5857c390..00000000 --- a/web/dbdoc/STSPL_1107_R.html +++ /dev/null @@ -1,131 +0,0 @@ - -Stuart CXB Mouse Spleen Normative Affy M430 2.0 (Nov 2007) RMA data set - - - - - - - - - - - - -
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Stuart CXB Mouse Spleen Normative Affy M430 2.0 (Nov 2007) RMA data set -modify this page

Accession number: GN153

- -This is a new and untested data set from John Stuart and colleagues, VA Medical Center, Memphis, TN. - -

Please contact Rob Williams (rwilliam@nb.utmem.edu) for access. - - -

The recombinant inbred CXB (BALB/cBy x C57BL/6By) RI set have often been used to study the influence of non-H-2 chromosomal regions on the progression of collagen-induced arthritis (CIA). C57BL/6By mice are of intermediate susceptibility to CIA while BALB/cBy mice are resistant, but are highly susceptible to proteoglycan-induced arthritis. While antigen presentation is H-2 directed, the amount of disease that results is thought to be driven by regions outside of the MHC. CXB strains that are H-2b are predicted to show variation in the frequency and severity of disease relative to C57BL/6By, depending on which BALB/cBy chromosome regions are present. Nine of thirteen CXB strains are H-2b (2, 3, 5, 6, 7, 8, 10, 11 and 13) while one has a recombined H-2 region (CXB9). The four H-2d strains were crossed with C57Bl/6ByJ to generate F1 mice that could present collagen via the B allele at the H-2b locus, while possibly identifying BALB/cBy alleles that would have a dominant effect on disease progression. A number of disease and immunological parameters were collected. (text from Dana Marshall, Jan 2008) - -

Gene expression analysis was performed using samples from resting naive spleens from adult female adult mice. Information on these cases is provided below. -

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IndexTube IDRNA IDStrainAgeSourcePool size
1R2440S1R2440SBALB/cByJ60UTHSCn/a
2R2435S1R2435SBALB/cByJ83JAXn/a
3R2394S1R2394SC57BL/6BYJ51JAXn/a
4R2395S1R2395SC57BL/6BYJ51JAXn/a
5R2410S1R2410SCXB155JAXn/a
6R2655S1R2655SCXB158JAXn/a
7R2392S1R2392SCXB253JAXn/a
8R2393S1R2393SCXB253JAXn/a
9R2430S1R2430SCXB341JAXn/a
10R2412S1R2412SCXB347JAXn/a
11R2432S1R2432SCXB447JAXn/a
12R2413S1R2413SCXB458JAXn/a
13R2441S1R2441SCXB567UTHSCn/a
14R2444S1R2444SCXB580UTHSCn/a
15R2437S1R2437SCXB647JAXn/a
16R2414S1R2414SCXB649JAXn/a
17R2416S1R2416SCXB758JAXn/a
18R2415S1R2415SCXB763JAXn/a
19R2418S1R2418SCXB841JAXn/a
20R2417S1R2417SCXB854JAXn/a
21R2420S1R2420SCXB953JAXn/a
22R2419S1R2419SCXB954JAXn/a
23R2422S1R2422SCXB1048JAXn/a
24R2421S1R2421SCXB1053JAXn/a
25R2423S1R2423SCXB1158JAXn/a
26R2424S1R2424SCXB1177JAXn/a
27R2425S1R2425SCXB1247JAXn/a
28R2442S1R2442SCXB1276UTHSCn/a
29R2427S1R2427SCXB1349JAXn/a
30R2426S1R2426SCXB1356JAXn/a
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