-The current study focused on the extent genetic diversity within a species (Mus musculus) affects gene
-co-expression network structure. To examine this issue, we have created a new mouse resource, a heterogeneous
-stock (HS) formed from the same eight inbred strains that have been used to create the collaborative cross (CC). The
-eight inbred strains capture > 90% of the genetic diversity available within the species. For contrast with the HS-CC, a
-C57BL/6J (B6) × DBA/2J (D2) F2 intercross and the HS4, derived from crossing the B6, D2, BALB/cJ and LP/J strains,
-were used. Brain (striatum) gene expression data were obtained using the Illumina Mouse WG 6.1 array, and the data
-sets were interrogated using a weighted gene co-expression network analysis (WGCNA).
-Read full article: Genetic diversity and striatal gene networks: focus on the heterogeneous stock-collaborative cross (HS-CC) mouse.
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