From 0dd04c5ca0521f59f93b45663bdfd67c916a9f3c Mon Sep 17 00:00:00 2001
From: Arthur Centeno
Date: Thu, 13 May 2021 08:05:30 +0000
Subject: Fix load_phenotypes to run with GN2 latest
---
scripts/maintenance/datastructure.py | 177 +++++++++++++++++++++++++++++++
scripts/maintenance/load_phenotypes.py | 43 ++++----
scripts/maintenance/utilities.py | 89 ++++++++++++++++
wqflask/wqflask/templates/tutorials.html | 1 +
4 files changed, 292 insertions(+), 18 deletions(-)
create mode 100755 scripts/maintenance/datastructure.py
create mode 100644 scripts/maintenance/utilities.py
diff --git a/scripts/maintenance/datastructure.py b/scripts/maintenance/datastructure.py
new file mode 100755
index 00000000..9f3e8b1e
--- /dev/null
+++ b/scripts/maintenance/datastructure.py
@@ -0,0 +1,177 @@
+import utilities
+
+def get_probesetfreezes(inbredsetid):
+ cursor, con = utilities.get_cursor()
+ sql = """
+ SELECT ProbeSetFreeze.`Id`, ProbeSetFreeze.`Name`, ProbeSetFreeze.`FullName`
+ FROM ProbeSetFreeze, ProbeFreeze
+ WHERE ProbeSetFreeze.`ProbeFreezeId`=ProbeFreeze.`Id`
+ AND ProbeFreeze.`InbredSetId`=%s
+ """
+ cursor.execute(sql, (inbredsetid))
+ return cursor.fetchall()
+
+def get_probesetfreeze(probesetfreezeid):
+ cursor, con = utilities.get_cursor()
+ sql = """
+ SELECT ProbeSetFreeze.`Id`, ProbeSetFreeze.`Name`, ProbeSetFreeze.`FullName`
+ FROM ProbeSetFreeze
+ WHERE ProbeSetFreeze.`Id`=%s
+ """
+ cursor.execute(sql, (probesetfreezeid))
+ return cursor.fetchone()
+
+def get_strains(inbredsetid):
+ cursor, con = utilities.get_cursor()
+ sql = """
+ SELECT Strain.`Id`, Strain.`Name`
+ FROM StrainXRef, Strain
+ WHERE StrainXRef.`InbredSetId`=%s
+ AND StrainXRef.`StrainId`=Strain.`Id`
+ ORDER BY StrainXRef.`OrderId`
+ """
+ cursor.execute(sql, (inbredsetid))
+ return cursor.fetchall()
+
+def get_inbredset(probesetfreezeid):
+ cursor, con = utilities.get_cursor()
+ sql = """
+ SELECT InbredSet.`Id`, InbredSet.`Name`, InbredSet.`FullName`
+ FROM InbredSet, ProbeFreeze, ProbeSetFreeze
+ WHERE InbredSet.`Id`=ProbeFreeze.`InbredSetId`
+ AND ProbeFreeze.`Id`=ProbeSetFreeze.`ProbeFreezeId`
+ AND ProbeSetFreeze.`Id`=%s
+ """
+ cursor.execute(sql, (probesetfreezeid))
+ return cursor.fetchone()
+
+def get_species(inbredsetid):
+ cursor, con = utilities.get_cursor()
+ sql = """
+ SELECT Species.`Id`, Species.`Name`, Species.`MenuName`, Species.`FullName`
+ FROM InbredSet, Species
+ WHERE InbredSet.`Id`=%s
+ AND InbredSet.`SpeciesId`=Species.`Id`
+ """
+ cursor.execute(sql, (inbredsetid))
+ return cursor.fetchone()
+
+def get_genofreeze_byinbredsetid(inbredsetid):
+ cursor, con = utilities.get_cursor()
+ sql = """
+ SELECT GenoFreeze.`Id`, GenoFreeze.`Name`, GenoFreeze.`FullName`, GenoFreeze.`InbredSetId`
+ FROM GenoFreeze
+ WHERE GenoFreeze.`InbredSetId`=%s
+ """
+ cursor.execute(sql, (inbredsetid))
+ return cursor.fetchone()
+
+def get_nextdataid_genotype():
+ cursor, con = utilities.get_cursor()
+ sql = """
+ SELECT GenoData.`Id`
+ FROM GenoData
+ ORDER BY GenoData.`Id` DESC
+ LIMIT 1
+ """
+ cursor.execute(sql)
+ re = cursor.fetchone()
+ dataid = re[0]
+ dataid += 1
+ return dataid
+
+def get_nextdataid_phenotype():
+ cursor, con = utilities.get_cursor()
+ sql = """
+ SELECT PublishData.`Id`
+ FROM PublishData
+ ORDER BY PublishData.`Id` DESC
+ LIMIT 1
+ """
+ cursor.execute(sql)
+ re = cursor.fetchone()
+ dataid = re[0]
+ dataid += 1
+ return dataid
+
+def get_nextorderid_strainxref(inbredsetid):
+ cursor, con = utilities.get_cursor()
+ sql = """
+ SELECT StrainXRef.`OrderId`
+ FROM StrainXRef
+ WHERE StrainXRef.`InbredSetId`=%s
+ ORDER BY StrainXRef.`OrderId` DESC
+ LIMIT 1
+ """
+ cursor.execute(sql, (inbredsetid))
+ re = cursor.fetchone()
+ if re:
+ orderid = re[0] + 1
+ else:
+ orderid = 1
+ return orderid
+
+def insert_strain(inbredsetid, strainname):
+ speciesid = get_species(inbredsetid)[0]
+ cursor, con = utilities.get_cursor()
+ sql = """
+ INSERT INTO Strain
+ SET
+ Strain.`Name`=%s,
+ Strain.`Name2`=%s,
+ Strain.`SpeciesId`=%s
+ """
+ cursor.execute(sql, (strainname, strainname, speciesid))
+
+def insert_strainxref(inbredsetid, strainid):
+ orderid = get_nextorderid_strainxref(inbredsetid)
+ cursor, con = utilities.get_cursor()
+ sql = """
+ INSERT INTO StrainXRef
+ SET
+ StrainXRef.`InbredSetId`=%s,
+ StrainXRef.`StrainId`=%s,
+ StrainXRef.`OrderId`=%s,
+ StrainXRef.`Used_for_mapping`=%s,
+ StrainXRef.`PedigreeStatus`=%s
+ """
+ cursor.execute(sql, (inbredsetid, strainid, orderid, "N", None))
+
+def get_strain(inbredsetid, strainname):
+ speciesid = get_species(inbredsetid)[0]
+ cursor, con = utilities.get_cursor()
+ sql = """
+ SELECT Strain.`Id`, Strain.`Name`
+ FROM Strain
+ WHERE Strain.`SpeciesId`=%s
+ AND Strain.`Name` LIKE %s
+ """
+ cursor.execute(sql, (speciesid, strainname))
+ return cursor.fetchone()
+
+def get_strainxref(inbredsetid, strainid):
+ cursor, con = utilities.get_cursor()
+ sql = """
+ SELECT StrainXRef.`StrainId`
+ FROM StrainXRef
+ WHERE StrainXRef.`InbredSetId`=%s
+ AND StrainXRef.`StrainId`=%s
+ """
+ cursor.execute(sql, (inbredsetid, strainid))
+ return cursor.fetchone()
+
+def get_strain_sure(inbredsetid, strainname, updatestrainxref=None):
+ strain = get_strain(inbredsetid, strainname)
+ if not strain:
+ insert_strain(inbredsetid, strainname)
+ strain = get_strain(inbredsetid, strainname)
+ strainxref = get_strainxref(inbredsetid, strain[0])
+ if not strainxref and updatestrainxref:
+ insert_strainxref(inbredsetid, strain[0])
+ return strain
+
+def get_strains_bynames(inbredsetid, strainnames, updatestrainxref=None):
+ strains = []
+ for strainname in strainnames:
+ strains.append(get_strain_sure(inbredsetid, strainname, updatestrainxref))
+ return strains
diff --git a/scripts/maintenance/load_phenotypes.py b/scripts/maintenance/load_phenotypes.py
index 759d2eec..aa02d0cd 100755
--- a/scripts/maintenance/load_phenotypes.py
+++ b/scripts/maintenance/load_phenotypes.py
@@ -1,3 +1,11 @@
+# Load Python3 environment with GN2 utilities:
+#
+# source /usr/local/guix-profiles/gn-latest-20210512/etc/profile
+#
+# and run
+#
+# python load_phenotypes.py [args...]
+
import sys
import csv
@@ -9,35 +17,34 @@ def main(argv):
config = utilities.get_config(argv[1])
print("config:")
for item in config.items('config'):
- print(("\t%s" % (str(item))))
+ print("\t%s" % (str(item)))
# var
inbredsetid = config.get('config', 'inbredsetid')
- print(("inbredsetid: %s" % inbredsetid))
+ print("inbredsetid: %s" % inbredsetid)
species = datastructure.get_species(inbredsetid)
speciesid = species[0]
- print(("speciesid: %s" % speciesid))
+ print("speciesid: %s" % speciesid)
dataid = datastructure.get_nextdataid_phenotype()
- print(("next data id: %s" % dataid))
+ print("next data id: %s" % dataid)
cursor, con = utilities.get_cursor()
# datafile
datafile = open(config.get('config', 'datafile'), 'r')
phenotypedata = csv.reader(datafile, delimiter='\t', quotechar='"')
- phenotypedata_head = next(phenotypedata)
- print(("phenotypedata head:\n\t%s" % phenotypedata_head))
+ phenotypedata_head = phenotypedata.next()
+ print("phenotypedata head:\n\t%s" % phenotypedata_head)
strainnames = phenotypedata_head[1:]
strains = datastructure.get_strains_bynames(inbredsetid=inbredsetid, strainnames=strainnames, updatestrainxref="yes")
# metafile
metafile = open(config.get('config', 'metafile'), 'r')
phenotypemeta = csv.reader(metafile, delimiter='\t', quotechar='"')
- phenotypemeta_head = next(phenotypemeta)
- print(("phenotypemeta head:\n\t%s" % phenotypemeta_head))
- print()
+ phenotypemeta_head = phenotypemeta.next()
+ print("phenotypemeta head:\n\t%s" % phenotypemeta_head)
# load
for metarow in phenotypemeta:
#
- datarow_value = next(phenotypedata)
- datarow_se = next(phenotypedata)
- datarow_n = next(phenotypedata)
+ datarow_value = phenotypedata.next()
+ datarow_se = phenotypedata.next()
+ datarow_n = phenotypedata.next()
# Phenotype
sql = """
INSERT INTO Phenotype
@@ -67,7 +74,7 @@ def main(argv):
))
rowcount = cursor.rowcount
phenotypeid = con.insert_id()
- print(("INSERT INTO Phenotype: %d record: %d" % (rowcount, phenotypeid)))
+ print("INSERT INTO Phenotype: %d record: %d" % (rowcount, phenotypeid))
# Publication
publicationid = None # reset
pubmed_id = utilities.to_db_string(metarow[0], None)
@@ -81,7 +88,7 @@ def main(argv):
re = cursor.fetchone()
if re:
publicationid = re[0]
- print(("get Publication record: %d" % publicationid))
+ print("get Publication record: %d" % publicationid)
if not publicationid:
sql = """
INSERT INTO Publication
@@ -109,7 +116,7 @@ def main(argv):
))
rowcount = cursor.rowcount
publicationid = con.insert_id()
- print(("INSERT INTO Publication: %d record: %d" % (rowcount, publicationid)))
+ print("INSERT INTO Publication: %d record: %d" % (rowcount, publicationid))
# data
for index, strain in enumerate(strains):
#
@@ -158,14 +165,14 @@ def main(argv):
cursor.execute(sql, (inbredsetid, phenotypeid, publicationid, dataid, ""))
rowcount = cursor.rowcount
publishxrefid = con.insert_id()
- print(("INSERT INTO PublishXRef: %d record: %d" % (rowcount, publishxrefid)))
+ print("INSERT INTO PublishXRef: %d record: %d" % (rowcount, publishxrefid))
# for loop next
dataid += 1
- print()
+ print
# release
con.close()
if __name__ == "__main__":
- print(("command line arguments:\n\t%s" % sys.argv))
+ print("command line arguments:\n\t%s" % sys.argv)
main(sys.argv)
print("exit successfully")
diff --git a/scripts/maintenance/utilities.py b/scripts/maintenance/utilities.py
new file mode 100644
index 00000000..886410c2
--- /dev/null
+++ b/scripts/maintenance/utilities.py
@@ -0,0 +1,89 @@
+import MySQLdb
+import re
+import configparser
+
+def get_cursor():
+ host = 'tux.uthsc.edu'
+ user = 'webqtlout'
+ passwd = 'webqtlout'
+ db = 'db_webqtl'
+ con = MySQLdb.Connect(db=db, host=host, user=user, passwd=passwd)
+ cursor = con.cursor()
+ return cursor, con
+
+def clearspaces(s, default=None):
+ if s:
+ s = re.sub('\s+', ' ', s)
+ s = s.strip()
+ return s
+ else:
+ return default
+
+def to_dic(keys, values):
+ dic = {}
+ for i in range(len(keys)):
+ key = keys[i]
+ value = values[i]
+ dic[key] = value
+ return dic
+
+def overlap(dic1, dic2):
+ keys = []
+ values1 = []
+ values2 = []
+ for key in dic1.keys():
+ if key in dic2:
+ value1 = dic1[key]
+ value2 = dic2[key]
+ if value1 and value2:
+ keys.append(key)
+ values1.append(value1)
+ values2.append(value2)
+ return keys, values1, values2
+
+def to_db_string(s, default):
+ if s:
+ s = s.strip()
+ if len(s) == 0:
+ return default
+ elif s == 'x':
+ return default
+ else:
+ return s
+ else:
+ return default
+
+def to_db_float(s, default):
+ if s:
+ s = s.strip()
+ if len(s) == 0:
+ return default
+ elif s == 'x':
+ return default
+ else:
+ try:
+ return float(s)
+ except:
+ return default
+ else:
+ return default
+
+def to_db_int(s, default):
+ if s:
+ s = s.strip()
+ if len(s) == 0:
+ return default
+ elif s == 'x':
+ return default
+ else:
+ try:
+ return int(s)
+ except:
+ return default
+ else:
+ return default
+
+def get_config(configfile):
+ config = configparser.ConfigParser()
+ config.read(configfile)
+ return config
diff --git a/wqflask/wqflask/templates/tutorials.html b/wqflask/wqflask/templates/tutorials.html
index ce5d0e3d..ed1b6f3a 100644
--- a/wqflask/wqflask/templates/tutorials.html
+++ b/wqflask/wqflask/templates/tutorials.html
@@ -10,6 +10,7 @@
Statistical and genetic functions,
and initial mapping results for Rat GWAS P50 as implemented in GeneNetwork.org
Webinar Series - Quantitative Genetics Tools for Mapping Trait Variation to Mechanisms, Therapeutics, and Interventions
+ TESTING
--
cgit v1.2.3