diff options
Diffstat (limited to 'wqflask/maintenance/generate_kinship_from_bimbam.py')
-rw-r--r-- | wqflask/maintenance/generate_kinship_from_bimbam.py | 66 |
1 files changed, 0 insertions, 66 deletions
diff --git a/wqflask/maintenance/generate_kinship_from_bimbam.py b/wqflask/maintenance/generate_kinship_from_bimbam.py deleted file mode 100644 index 9f01d094..00000000 --- a/wqflask/maintenance/generate_kinship_from_bimbam.py +++ /dev/null @@ -1,66 +0,0 @@ -#!/usr/bin/python - -""" -Generate relatedness matrix files for GEMMA from BIMBAM genotype/phenotype files - -This file goes through all of the BIMBAM files in the bimbam diretory -and uses GEMMA to generate their corresponding kinship/relatedness matrix file - -""" - -import sys -sys.path.append("..") -import os -import glob - - -class GenerateKinshipMatrices: - def __init__(self, group_name, geno_file, pheno_file): - self.group_name = group_name - self.geno_file = geno_file - self.pheno_file = pheno_file - - def generate_kinship(self): - gemma_command = "/gnu/store/xhzgjr0jvakxv6h3blj8z496xjig69b0-profile/bin/gemma -g " + self.geno_file + \ - " -p " + self.pheno_file + \ - " -gk 1 -outdir /home/zas1024/genotype_files/genotype/bimbam/ -o " + self.group_name - print("command:", gemma_command) - os.system(gemma_command) - - @classmethod - def process_all(self, geno_dir, bimbam_dir): - os.chdir(geno_dir) - for input_file in glob.glob("*"): - if not input_file.endswith(('geno', '.geno.gz')): - continue - group_name = ".".join(input_file.split('.')[:-1]) - if group_name == "HSNIH-Palmer": - continue - geno_input_file = os.path.join( - bimbam_dir, group_name + "_geno.txt") - pheno_input_file = os.path.join( - bimbam_dir, group_name + "_pheno.txt") - convertob = GenerateKinshipMatrices( - group_name, geno_input_file, pheno_input_file) - try: - convertob.generate_kinship() - except EmptyConfigurations as why: - print(" No config info? Continuing...") - continue - except Exception as why: - - print(" Exception:", why) - print(traceback.print_exc()) - print(" Found in row %s at tabular column %s" % (convertob.latest_row_pos, - convertob.latest_col_pos)) - print(" Column is:", convertob.latest_col_value) - print(" Row is:", convertob.latest_row_value) - break - - -if __name__ == "__main__": - Geno_Directory = """/export/local/home/zas1024/genotype_files/genotype/""" - Bimbam_Directory = """/export/local/home/zas1024/genotype_files/genotype/bimbam/""" - GenerateKinshipMatrices.process_all(Geno_Directory, Bimbam_Directory) - - # ./gemma -g /home/zas1024/genotype_files/genotype/bimbam/BXD_geno.txt -p /home/zas1024/genotype_files/genotype/bimbam/BXD_pheno.txt -gk 1 -o BXD |