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Top addiction related genes


These genes are ranked by the number of PubMed abstracts that contain the name of the gene and one or more addiction related keyword. Alias were obtained from NCBI gene database and have been curated to remove most, but not all, false matches.
  1. FOS (AP\ 1; C\ FOS; CFOS; FOS\ PROTO\ ONCOGENE,\ AP\ 1\ TRANSCRIPTION\ FACTOR\ SUBUNIT)
  2. BDNF (ANON2; BRAIN\ DERIVED\ NEUROTROPHIC\ FACTOR; BULN2)
  3. TH (DYT14; DYT5B; TYROSINE\ HYDROXYLASE; TYROSINEHYDROXYLASE)
  4. OPRM1 (LMOR; M\ OR\ 1; MOR1; OPIOID\ RECEPTOR\ MU\ 1; OPRM)
  5. CNR1 (CNRS1; PROTOCADHERIN\ ALPHA\ CLUSTER,\ COMPLEX\ LOCUS)
  6. DRD2 (D2DR; DOPAMINE\ RECEPTOR\ D2)
  7. CREB1 (CAMP\ RESPONSIVE\ ELEMENT\ BINDING\ PROTEIN\ 1; CREB; CREB\ 1)
  8. SLC6A4 (5\ HTT; 5\ HTTLPR; 5HTT; 5HTTLPR; HSERT; OCD1; SERT; SERT1; SOLUTE\ CARRIER\ FAMILY\ 6\ MEMBER\ 4)
  9. TNF (TNF\ ALPHA; TNFA; TNFALPHA; TNFSF2; TNLG1F; TUMOR\ NECROSIS\ FACTOR)
  10. CYP2B6 (CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; CYTOCHROME\ P450\ FAMILY\ 2\ SUBFAMILY\ B\ MEMBER\ 6; EFVM; IIB1; P450)
  11. NPY (NEUROPEPTIDE\ Y; NEUROPEPTIDEY; PYY4)
  12. GRM5 (GLUTAMATE\ METABOTROPIC\ RECEPTOR\ 5; GPRC1E; MGLU5; MGLUR5; PPP1R86)
  13. GRIN2B (EIEE27; GLUN2B; GLUTAMATE\ IONOTROPIC\ RECEPTOR\ NMDA\ TYPE\ SUBUNIT\ 2B; HNR3; MRD6; NMDAR2B; NR2B)
  14. HTR1A (5\ HT\ 1A; 5\ HT1A; 5\ HYDROXYTRYPTAMINE\ RECEPTOR\ 1A; 5HT1A; 5HT1A; ADRB2RL1; ADRBRL1; PFMCD)
  15. GRIA1 (GLUA1; GLUH1; GLUR1; GLURA; GLUTAMATE\ IONOTROPIC\ RECEPTOR\ AMPA\ TYPE\ SUBUNIT\ 1; HBGR1)
  16. ALDH2 (ALDEHYDE\ DEHYDROGENASE\ 2\ FAMILY\ MEMBER; ALDH\ E2; ALDHE2; ALDHI; ALDM)
  17. HTR2A (5\ HT2A; 5\ HYDROXYTRYPTAMINE\ RECEPTOR\ 2A; 5HT2A; HTR2)
  18. CRHR1 (CORTICOTROPIN\ RELEASING\ HORMONE\ RECEPTOR\ 1; CRF\ R; CRF\ R\ 1; CRF\ R1; CRF1; CRFR; CRFR\ 1; CRFR1; CRH\ R\ 1; CRH\ R1; CRHR; CRHR1L)
  19. GRM2 (GLUR2; GLUTAMATE\ METABOTROPIC\ RECEPTOR\ 2; GPRC1B; MGLU2; MGLUR2)
  20. CHRNA5 (CHOLINERGIC\ RECEPTOR\ NICOTINIC\ ALPHA\ 5\ SUBUNIT; LNCR2)
  21. IL6 (BSF\ 2; BSF2; IFN\ BETA\ 2; IFNB2; IL\ 6; INTERLEUKIN\ 6; INTERLEUKIN6)
  22. COMT (CATECHOL\ O\ METHYLTRANSFERASE; HEL\ S\ 98N)
  23. PDYN (ADCA; PENKB; PRODYNORPHIN; SCA23)
  24. FAAH1 (FAAH\ 1; FATTY\ ACID\ AMIDE\ HYDROLASE; PSAB)
  25. NPS (NEUROPEPTIDE\ S)
  26. MAPK3 (ERK\ 1; ERK1; ERT2; HS44KDAP; HUMKER1A; MITOGEN\ ACTIVATED\ PROTEIN\ KINASE\ 3; P44\ ERK1; P44\ MAPK; P44ERK1; P44ERK1; P44MAPK; P44MAPK; PRKM3)
  27. FOSB (AP\ 1; FOSB\ PROTO\ ONCOGENE,\ AP\ 1\ TRANSCRIPTION\ FACTOR\ SUBUNIT; G0S3; GOS3; GOSB)
  28. CRH (CORTICOTROPIN\ RELEASING\ HORMONE; CRH1)
  29. TLR4 (ARMD10; CD284; TLR\ 4; TOLL\ LIKE\ RECEPTOR\ 4)
  30. GRIA2 (GLUA2; GLUR\ 2; GLUR\ B; GLUR\ K2; GLUR2; GLUR2; GLURB; GLURB; GLURK2; GLUTAMATE\ IONOTROPIC\ RECEPTOR\ AMPA\ TYPE\ SUBUNIT\ 2; HBGR2)
  31. CYP2A6 (CPA6; CYP2A; CYP2A3; CYPIIA6; CYTOCHROME\ P450\ FAMILY\ 2\ SUBFAMILY\ A\ MEMBER\ 6; P450C2A; P450PB)
  32. HTR2C (5\ HT1C; 5\ HT2C; 5\ HTR2C; 5\ HYDROXYTRYPTAMINE\ RECEPTOR\ 2C; 5HT1C; 5HT2C; 5HTR2C; HTR1C)
  33. ADH1B (ADH2; ALCOHOL\ DEHYDROGENASE\ 1B\ CLASS\ I\ ,\ BETA\ POLYPEPTIDE; HEL\ S\ 117)
  34. DRD4 (D4DR; DOPAMINE\ RECEPTOR\ D4)
  35. ARC (ACTIVITY\ REGULATED\ CYTOSKELETON\ ASSOCIATED\ PROTEIN; ARG3.1; HARC)
  36. MAOA (BRNRS; MAO\ A; MONOAMINE\ OXIDASE\ A)
  37. CYP2E1 (CPE1; CYP2E; CYTOCHROME\ P450\ FAMILY\ 2\ SUBFAMILY\ E\ MEMBER\ 1; P450\ J; P450C2E; P450J)
  38. SLC1A2 (EAAT2; EIEE41; GLT\ 1; GLT1; HBGT; SOLUTE\ CARRIER\ FAMILY\ 1\ MEMBER\ 2)
  39. GRIN2A (EPND; FESD; GLUN2A; GLUTAMATE\ IONOTROPIC\ RECEPTOR\ NMDA\ TYPE\ SUBUNIT\ 2A; NMDAR2A; NR2A)
  40. POMC (OBAIRH; PROOPIOMELANOCORTIN)
  41. SLC6A3 (DAT1; PKDYS; PKDYS1; SOLUTE\ CARRIER\ FAMILY\ 6\ MEMBER\ 3)
  42. NGF (BETA\ NGF; BETANGF; HSAN5; NERVE\ GROWTH\ FACTOR; NGFB)
  43. DBH (DOPAMINE\ BETA\ HYDROXYLASE; ORTHYP1)
  44. PENK (PENK\ A; PENKA; PROENKEPHALIN)
  45. HTR1B (5\ HT\ 1B; 5\ HT\ 1D\ BETA; 5\ HT1B; 5\ HT1DB; 5\ HYDROXYTRYPTAMINE\ RECEPTOR\ 1B; 5HT1B; 5HT1DB; HTR1D2; HTR1DB)
  46. JUN (AP\ 1; C\ JUN; CJUN; CJUN; JUN\ PROTO\ ONCOGENE,\ AP\ 1\ TRANSCRIPTION\ FACTOR\ SUBUNIT)
  47. CASP3 (CASPASE\ 3; CASPASE3; CPP32; CPP32B; SCA\ 1; SCA1)
  48. CHRNA3 (BAIPRCK; CHOLINERGIC\ RECEPTOR\ NICOTINIC\ ALPHA\ 3\ SUBUNIT; LNCR2; NACHRA3; PAOD2)
  49. NEUROTENSIN (NMN\ 125; NMN125; NT/N; NTS1)
  50. NTRK2 (EIEE58; GP145\ TRKB; GP145TRKB; NEUROTROPHIC\ RECEPTOR\ TYROSINE\ KINASE\ 2; OBHD; TRK\ B; TRKB; TRKB)
  51. CAMK2G (CALCIUM/CALMODULIN\ DEPENDENT\ PROTEIN\ KINASE\ II\ GAMMA; CAMK; CAMK\ II; CAMKG; CAMKII; MRD59)
  52. TRPV1 (TRANSIENT\ RECEPTOR\ POTENTIAL\ CATION\ CHANNEL\ SUBFAMILY\ V\ MEMBER\ 1)
  53. CYP2D6 (CPD6; CYP2D; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID6; CYTOCHROME\ P450\ FAMILY\ 2\ SUBFAMILY\ D\ MEMBER\ 6; P450\ DB1; P450C2D; P450DB1)
  54. CORT (CORTISTATIN; CST\ 14; CST\ 17; CST\ 29; CST14; CST17; CST29)
  55. GFAP (ALXDRD; GLIAL\ FIBRILLARY\ ACIDIC\ PROTEIN)
  56. GABRA2 (EIEE78; GAMMA\ AMINOBUTYRIC\ ACID\ TYPE\ A\ RECEPTOR\ SUBUNIT\ ALPHA2)
  57. EGR1 (AT225; EARLY\ GROWTH\ RESPONSE\ 1; G0S30; KROX\ 24; KROX24; NGFI\ A; NGFIA; TIS8; ZIF\ 268; ZIF268; ZNF225)
  58. NOS1 (BNOS; IHPS1; N\ NOS; NC\ NOS; NCNOS; NITRIC\ OXIDE\ SYNTHASE\ 1; NNOS; NNOS)
  59. ANKK1 (ANKYRIN\ REPEAT\ AND\ KINASE\ DOMAIN\ CONTAINING\ 1; PKK2; SGK288)
  60. CYP3A4 (CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; CYTOCHROME\ P450\ FAMILY\ 3\ SUBFAMILY\ A\ MEMBER\ 4; NF\ 25; NF25; P450C3; P450PCN1)
  61. PCDHA4 (CNR1; CNRN1; CRNR1; PCDH\ ALPHA4; PCDHALPHA4; PROTOCADHERIN\ ALPHA\ 4)
  62. IL10 (CSIF; GVHDS; IL\ 10; IL10A; INTERLEUKIN\ 10; INTERLEUKIN10; TGIF)
  63. MTOR (FRAP; FRAP1; FRAP2; MECHANISTIC\ TARGET\ OF\ RAPAMYCIN\ KINASE; RAFT1; RAPT1)
  64. TRH (PRO\ TRH; PROTRH; THYROTROPIN\ RELEASING\ HORMONE)
  65. CHRNB4 (CHOLINERGIC\ RECEPTOR\ NICOTINIC\ BETA\ 4\ SUBUNIT)
  66. GRM1 (GLUTAMATE\ METABOTROPIC\ RECEPTOR\ 1; GPRC1A; MGLU1; MGLUR1; PPP1R85; SCA44; SCAR13)
  67. GDNF (ATF1; ATF2; GLIAL\ CELL\ DERIVED\ NEUROTROPHIC\ FACTOR; HFB1\ GDNF; HFB1GDNF; HSCR3)
  68. DRD1 (DADR; DOPAMINE\ RECEPTOR\ D1; DRD1A)
  69. GRIN1 (GLUN1; GLUTAMATE\ IONOTROPIC\ RECEPTOR\ NMDA\ TYPE\ SUBUNIT\ 1; MRD8; NDHMSD; NDHMSR; NMD\ R1; NMDA1; NMDAR1; NMDR1)
  70. BCHE (BCHED; BUTYRYLCHOLINESTERASE; CHE1; CHE2)
  71. CCL2 (C\ C\ MOTIF\ CHEMOKINE\ LIGAND\ 2; GDCF\ 2; GDCF2; HC11; HSMCR30; MCAF; MCP\ 1; MCP1; SCYA2; SMC\ CF; SMCCF)
  72. ADH1C (ADH3; ALCOHOL\ DEHYDROGENASE\ 1C\ CLASS\ I\ ,\ GAMMA\ POLYPEPTIDE)
  73. WARS1 (GAMMA\ 2; GAMMA2; HMN9; IFI53; IFP53; TRYPTOPHANYL\ TRNA\ SYNTHETASE\ 1; WARS)
  74. ADH4 (ADH\ 2; ADH2; ALCOHOL\ DEHYDROGENASE\ 4\ CLASS\ II\ ,\ PI\ POLYPEPTIDE; HEL\ S\ 4)
  75. PTGS2 (COX\ 2; COX2; GRIPGHS; HCOX\ 2; HCOX2; PGG/HS; PGHS\ 2; PGHS2; PHS\ 2; PHS2; PROSTAGLANDIN\ ENDOPEROXIDE\ SYNTHASE\ 2)
  76. HDAC9 (HD7B; HDAC; HDAC7; HDAC7B; HDAC9B; HDAC9FL; HDRP; HISTONE\ DEACETYLASE\ 9; MITR)
  77. RTN4 (NBLA00271; NBLA10545; NOGO; NSP\ CL; NSPCL; RETICULON\ 4; RETICULON4; RTN\ X; RTN4\ A; RTN4\ B1; RTN4\ B2; RTN4\ C; RTN4A; RTN4B1; RTN4B2; RTN4C; RTNX)
  78. PPP1R1B (DARPP\ 32; DARPP32; PROTEIN\ PHOSPHATASE\ 1\ REGULATORY\ INHIBITOR\ SUBUNIT\ 1B)
  79. PPARA (HPPAR; NR1C1; PEROXISOME\ PROLIFERATOR\ ACTIVATED\ RECEPTOR\ ALPHA; PPAR; PPARALPHA)
  80. BAX (BCL2\ ASSOCIATED\ X,\ APOPTOSIS\ REGULATOR; BCL2L4)
  81. OPRK1 (K\ OR\ 1; KOR\ 1; KOR1; OPIOID\ RECEPTOR\ KAPPA\ 1; OPRK)
  82. DRD3 (D3DR; DOPAMINE\ RECEPTOR\ D3; ETM1; FET1)
  83. BCL2 (BCL\ 2; BCL2; BCL2\ APOPTOSIS\ REGULATOR; PPP1R50)
  84. HOMER1 (HOMER; HOMER\ SCAFFOLD\ PROTEIN\ 1; HOMER1A; HOMER1B; HOMER1C; SYN47; VES\ 1; VES1)
  85. EGFR (EPIDERMAL\ GROWTH\ FACTOR\ RECEPTOR; ERBB; ERBB1; HER1; MENA; NISBD2; PIG61)
  86. ACHE (ACEE; ACETYLCHOLINESTERASE\ CARTWRIGHT\ BLOOD\ GROUP; ARACHE; N\ ACHE; NACHE)
  87. ADORA2A (A2AR; ADENOSINE\ A2A\ RECEPTOR; ADORA2; RDC8)
  88. ABCB1 (ABC20; ATP\ BINDING\ CASSETTE\ SUBFAMILY\ B\ MEMBER\ 1; CD243; CLCS; GP170; MDR1; P\ GP; PGY1)
  89. MGLL (HU\ K5; HUK5; MAGL; MONOGLYCERIDE\ LIPASE; MONOGLYCERIDELIPASE)
  90. CDK5 (CYCLIN\ DEPENDENT\ KINASE\ 5; LIS7; PSSALRE)
  91. PSENEN (ACNINV2; MDS033; MSTP064; PEN\ 2; PEN2; PRESENILIN\ ENHANCER,\ GAMMA\ SECRETASE\ SUBUNIT)
  92. SH2D3C (CHAT; NSP3; PRO34088; SH2\ DOMAIN\ CONTAINING\ 3C; SHEP1)
  93. IL1B (IL\ 1; IL1\ BETA; IL1BETA; IL1BETA; IL1F2; INTERLEUKIN\ 1\ BETA)
  94. CHAT (CHOACTASE; CHOLINE\ O\ ACETYLTRANSFERASE; CMS1A; CMS1A2; CMS6)
  95. CCL4 (ACT2; AT744.1; C\ C\ MOTIF\ CHEMOKINE\ LIGAND\ 4; G\ 26; HC21; LAG\ 1; LAG1; MIP\ 1\ BETA; MIP1B; MIP1B1; SCYA2; SCYA4)
  96. CALCA (CALC1; CALCITONIN\ RELATED\ POLYPEPTIDE\ ALPHA; CGRP; CGRP\ ALPHA; CGRP\ I; CGRP1; CGRPALPHA; CGRPI)
  97. S100A12 (CAAF1; CAGC; CGRP; MRP\ 6; MRP6; S100\ CALCIUM\ BINDING\ PROTEIN\ A12)
  98. OPRD1 (DOR1; OPIOID\ RECEPTOR\ DELTA\ 1; OPRD)
  99. JUNB (AP\ 1; JUNB\ PROTO\ ONCOGENE,\ AP\ 1\ TRANSCRIPTION\ FACTOR\ SUBUNIT)
  100. GSTM1 (GLUTATHIONE\ S\ TRANSFERASE\ MU\ 1; GST1; GSTM1\ 1; GSTM11; GSTM1A\ 1A; GSTM1A1A; GSTM1B\ 1B; GSTM1B1B; GTH4; GTM1; H\ B; MU\ 1)
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