From a637889f13c2151303998e411dc81f3196a974f6 Mon Sep 17 00:00:00 2001
From: hakangunturkun
Date: Mon, 7 Sep 2020 22:35:17 -0500
Subject: last version
---
templates/topAddictionGene.html | 302 ++++++++++++++--------------------------
1 file changed, 101 insertions(+), 201 deletions(-)
(limited to 'templates/topAddictionGene.html')
diff --git a/templates/topAddictionGene.html b/templates/topAddictionGene.html
index e62103a..95d6fde 100644
--- a/templates/topAddictionGene.html
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@@ -2,212 +2,112 @@
{% extends "layout.html" %}
{% block content %}
-
Top addiction related genes
+ Top addiction related genes
These genes are ranked by the number of PubMed abstracts that contain the name of the gene and one or more addiction related keyword. Alias were obtained from NCBI gene database and have been curated to remove most, but not all, false matches.
-- CNR1 (CNRS1; PROTOCADHERIN ALPHA CLUSTER, COMPLEX LOCUS)
- - OPRM1 (LMOR; M-OR-1; MOP; MOR; MOR1; OPRM; OPIOID RECEPTOR MU 1)
- - FOS (C-FOS; P55; FOS PROTO-ONCOGENE, AP-1 TRANSCRIPTION FACTOR SUBUNIT)
- - SLC6A3 (DAT; DAT1; PKDYS; PKDYS1; SOLUTE CARRIER FAMILY 6 MEMBER 3)
- - CRH (CRF; CRH1; CORTICOTROPIN RELEASING HORMONE)
- - BDNF (ANON2; BULN2; BRAIN DERIVED NEUROTROPHIC FACTOR)
- - DRD2 (D2DR; D2R; DOPAMINE RECEPTOR D2)
- - POMC (ACTH; OBAIRH; PROOPIOMELANOCORTIN)
- - CREB1 (CREB; CREB-1; CAMP RESPONSIVE ELEMENT BINDING PROTEIN 1)
- - OPRK1 (K-OR-1; KOR; KOR-1; OPRK; OPIOID RECEPTOR KAPPA 1)
- - TNF (TNF-ALPHA; TNFA; TNFSF2; TNLG1F; TUMOR NECROSIS FACTOR)
- - MAPK1 (ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; P41; P41MAPK; P42-MAPK; MITOGEN-ACTIVATED PROTEIN KINASE 1)
- - SLC6A4 (5-HTT; 5-HTTLPR; 5HTT; OCD1; SERT; SERT1; HSERT; SOLUTE CARRIER FAMILY 6 MEMBER 4)
- - CNR2 (CB-2; CB2; CX5; CANNABINOID RECEPTOR 2)
- - OXT (OT-NPI; OXT-NPI; OXYTOCIN; NEUROPHYSIN I PREPROPEPTIDE)
- - GRM5 (GPRC1E; MGLUR5; PPP1R86; MGLU5; GLUTAMATE METABOTROPIC RECEPTOR 5)
- - NPY (PYY4; NEUROPEPTIDE Y)
- - NOS1 (IHPS1; N-NOS; NC-NOS; NOS; BNOS; NNOS; NITRIC OXIDE SYNTHASE 1)
- - ALDH2 (ALDH-E2; ALDHI; ALDM; ALDEHYDE DEHYDROGENASE 2 FAMILY MEMBER)
- - PNOC (NOP; OFQ; PPNOC; PREPRONOCICEPTIN)
- - GRIA1 (GLUH1; GLUR1; GLURA; GLUA1; HBGR1; GLUTAMATE IONOTROPIC RECEPTOR AMPA TYPE SUBUNIT 1)
- - CHRNA5 (LNCR2; CHOLINERGIC RECEPTOR NICOTINIC ALPHA 5 SUBUNIT)
- - GRIN2B (EIEE27; GLUN2B; MRD6; NMDAR2B; NR2B; NR3; HNR3; GLUTAMATE IONOTROPIC RECEPTOR NMDA TYPE SUBUNIT 2B)
- - IL6 (BSF-2; BSF2; HGF; HSF; IFN-BETA-2; IFNB2; IL-6; INTERLEUKIN 6)
- - PDYN (ADCA; PENKB; SCA23; PRODYNORPHIN)
- - GRM2 (GLUR2; GPRC1B; MGLUR2; MGLU2; GLUTAMATE METABOTROPIC RECEPTOR 2)
- - HTR1A (5-HT-1A; 5-HT1A; 5HT1A; ADRB2RL1; ADRBRL1; PFMCD; 5-HYDROXYTRYPTAMINE RECEPTOR 1A)
- - COMT (HEL-S-98N; CATECHOL-O-METHYLTRANSFERASE)
- - CRHR1 (CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1L; CORTICOTROPIN RELEASING HORMONE RECEPTOR 1)
- - GGT1 (CD224; D22S672; D22S732; GGT; GGT 1; GGTD; GAMMA-GLUTAMYLTRANSFERASE 1)
- - MAPK3 (ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; P44-ERK1; P44-MAPK; MITOGEN-ACTIVATED PROTEIN KINASE 3)
- - CYP2A6 (CPA6; CYP2A; CYP2A3; CYPIIA6; P450C2A; P450PB; CYTOCHROME P450 FAMILY 2 SUBFAMILY A MEMBER 6)
- - ADH1B (ADH2; HEL-S-117; ALCOHOL DEHYDROGENASE 1B CLASS I , BETA POLYPEPTIDE)
- - GRIN1 (GLUN1; MRD8; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1; GLUTAMATE IONOTROPIC RECEPTOR NMDA TYPE SUBUNIT 1)
- - DRD4 (D4DR; DOPAMINE RECEPTOR D4)
- - NPS (NEUROPEPTIDE S)
- - HTR2A (5-HT2A; HTR2; 5-HYDROXYTRYPTAMINE RECEPTOR 2A)
- - GAD1 (CPSQ1; GAD; SCP; GLUTAMATE DECARBOXYLASE 1)
- - PENK (PENK-A; PROENKEPHALIN)
- - GRIA2 (GLUR2; GLURB; GLUA2; GLUR-K2; HBGR2; GLUTAMATE IONOTROPIC RECEPTOR AMPA TYPE SUBUNIT 2)
- - TLR4 (ARMD10; CD284; TLR-4; TOLL LIKE RECEPTOR 4)
- - MAOA (BRNRS; MAO-A; MONOAMINE OXIDASE A)
- - ARC (ARG3.1; HARC; ACTIVITY REGULATED CYTOSKELETON ASSOCIATED PROTEIN)
- - CHRNA3 (LNCR2; NACHRA3; PAOD2; CHOLINERGIC RECEPTOR NICOTINIC ALPHA 3 SUBUNIT)
- - FOSB (G0S3; GOS3; GOSB; FOSB PROTO-ONCOGENE, AP-1 TRANSCRIPTION FACTOR SUBUNIT)
- - CYP2E1 (CPE1; CYP2E; P450-J; P450C2E; CYTOCHROME P450 FAMILY 2 SUBFAMILY E MEMBER 1)
- - TRPV1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 1)
- - IFNA1 (IFL; IFN; IFN-ALPHA; IFN-ALPHAD; IFNA13; IFNA@; INTERFERON ALPHA 1)
- - HTR2C (5-HT1C; 5-HT2C; 5-HTR2C; 5HTR2C; HTR1C; 5-HYDROXYTRYPTAMINE RECEPTOR 2C)
- - DBH (ORTHYP1; DOPAMINE BETA-HYDROXYLASE)
- - NGF (BETA-NGF; HSAN5; NGFB; NERVE GROWTH FACTOR)
- - GABRA2 (GAMMA-AMINOBUTYRIC ACID TYPE A RECEPTOR ALPHA2 SUBUNIT)
- - NTRK2 (EIEE58; GP145-TRKB; OBHD; TRKB; TRK-B; NEUROTROPHIC RECEPTOR TYROSINE KINASE 2)
- - SLC1A2 (EAAT2; EIEE41; GLT-1; HBGT; SOLUTE CARRIER FAMILY 1 MEMBER 2)
- - GRIN2A (EPND; FESD; GLUN2A; LKS; NMDAR2A; NR2A; GLUTAMATE IONOTROPIC RECEPTOR NMDA TYPE SUBUNIT 2A)
- - CRP (PTX1; C-REACTIVE PROTEIN)
- - HTR1B (5-HT-1B; 5-HT-1D-BETA; 5-HT1B; 5-HT1DB; HTR1D2; HTR1DB; 5-HYDROXYTRYPTAMINE RECEPTOR 1B)
- - ANKK1 (PKK2; SGK288; ANKYRIN REPEAT AND KINASE DOMAIN CONTAINING 1)
- - OPRD1 (DOP; DOR1; OPRD; OPIOID RECEPTOR DELTA 1)
- - GFAP (ALXDRD; GLIAL FIBRILLARY ACIDIC PROTEIN)
- - CHRNB4 (CHOLINERGIC RECEPTOR NICOTINIC BETA 4 SUBUNIT)
- - CALCA (CALC1; CGRP; CGRP-I; CGRP1; PCT; CALCITONIN RELATED POLYPEPTIDE ALPHA)
- - IL10 (CSIF; GVHDS; IL-10; IL10A; TGIF; INTERLEUKIN 10)
- - JUN (AP1; C-JUN; JUN PROTO-ONCOGENE, AP-1 TRANSCRIPTION FACTOR SUBUNIT)
- - PSENEN (ACNINV2; MDS033; MSTP064; PEN-2; PEN2; PRESENILIN ENHANCER, GAMMA-SECRETASE SUBUNIT)
- - PTGS2 (COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; HCOX-2; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 2)
- - CYP3A4 (CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450C3; P450PCN1; CYTOCHROME P450 FAMILY 3 SUBFAMILY A MEMBER 4)
- - ADH1C (ADH3; ALCOHOL DEHYDROGENASE 1C CLASS I , GAMMA POLYPEPTIDE)
- - GDNF (ATF1; ATF2; HFB1-GDNF; HSCR3; GLIAL CELL DERIVED NEUROTROPHIC FACTOR)
- - GRM1 (GPRC1A; MGLU1; MGLUR1; PPP1R85; SCA44; SCAR13; GLUTAMATE METABOTROPIC RECEPTOR 1)
- - DRD1 (DADR; DRD1A; DOPAMINE RECEPTOR D1)
- - MTOR (FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS; MECHANISTIC TARGET OF RAPAMYCIN KINASE)
- - BCHE (BCHED; CHE1; CHE2; BUTYRYLCHOLINESTERASE)
- - PPARA (NR1C1; PPAR; PPARALPHA; HPPAR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA)
- - TRH (PRO-TRH; THYROTROPIN RELEASING HORMONE)
- - OPRL1 (KOR-3; NOCIR; NOPR; ORL1; OPIOID RELATED NOCICEPTIN RECEPTOR 1)
- - IL2 (IL-2; TCGF; INTERLEUKIN 2)
- - RTN4 (NOGO; NSP; NSP-CL; NBLA00271; NBLA10545; RTN-X; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C; RETICULON 4)
- - PPP1R1B (DARPP-32; DARPP32; PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 1B)
- - DRD3 (D3DR; ETM1; FET1; DOPAMINE RECEPTOR D3)
- - CYP2B6 (CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; CYTOCHROME P450 FAMILY 2 SUBFAMILY B MEMBER 6)
- - ABCB1 (ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1; ATP BINDING CASSETTE SUBFAMILY B MEMBER 1)
- - MGLL (HU-K5; HUK5; MAGL; MGL; MONOGLYCERIDE LIPASE)
- - CCL2 (GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF; C-C MOTIF CHEMOKINE LIGAND 2)
- - NOS2 (HEP-NOS; INOS; NOS2A; NITRIC OXIDE SYNTHASE 2)
- - EGFR (ERBB; ERBB1; HER1; NISBD2; PIG61; MENA; EPIDERMAL GROWTH FACTOR RECEPTOR)
- - HOMER1 (HOMER; HOMER1A; HOMER1B; HOMER1C; SYN47; VES-1; HOMER SCAFFOLD PROTEIN 1)
- - BCL2 (BCL-2; PPP1R50; BCL2 APOPTOSIS REGULATOR)
- - PLAT (T-PA; TPA; PLASMINOGEN ACTIVATOR, TISSUE TYPE)
- - IL1B (IL-1; IL1-BETA; IL1F2; INTERLEUKIN 1 BETA)
- - HCRTR1 (OX1R; HYPOCRETIN RECEPTOR 1)
- - CDK5 (LIS7; PSSALRE; CYCLIN DEPENDENT KINASE 5)
- - ADA2 (ADGF; CECR1; IDGFL; PAN; SNEDS; VAIHS; ADENOSINE DEAMINASE 2)
- - CHAT (CHOACTASE; CMS1A; CMS1A2; CMS6; CHOLINE O-ACETYLTRANSFERASE)
- - MAP2K7 (JNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4; MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7)
- - IL4 (BCGF-1; BCGF1; BSF-1; BSF1; IL-4; INTERLEUKIN 4)
- - BAX (BCL2L4; BCL2 ASSOCIATED X, APOPTOSIS REGULATOR)
- - SLC18A2 (PKDYS2; SVAT; SVMT; VAT2; VMAT2; SOLUTE CARRIER FAMILY 18 MEMBER A2)
- - MAPK8 (JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1C; MITOGEN-ACTIVATED PROTEIN KINASE 8)
- - ADORA2A (A2AR; ADORA2; RDC8; ADENOSINE A2A RECEPTOR)
- - PIK3CD (APDS; IMD14; P110DELTA; PI3K; P110D; PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA)
- - CHRNA4 (BFNC; EBN1; NACHRA4; NACRA4; CHOLINERGIC RECEPTOR NICOTINIC ALPHA 4 SUBUNIT)
- - SRC (SRC1; THC6; C-SRC; P60-SRC; SRC PROTO-ONCOGENE, NON-RECEPTOR TYROSINE KINASE)
- - NPFF (FMRFAL; NEUROPEPTIDE FF-AMIDE PEPTIDE PRECURSOR)
- - HOMER2 (ACPD; DFNA68; HOMER-2; VESL-2; HOMER SCAFFOLD PROTEIN 2)
- - EGR1 (AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225; EARLY GROWTH RESPONSE 1)
- - ACHE (ACEE; ARACHE; N-ACHE; ACETYLCHOLINESTERASE CARTWRIGHT BLOOD GROUP)
- - NKS1 ('EC-1; NATURAL KILLER CELL SUSCEPTIBILITY 1)
- - GNRH1 (GNRH; LHRH; LNRH; GONADOTROPIN RELEASING HORMONE 1)
- - EGF (HOMG4; EPIDERMAL GROWTH FACTOR)
- - CRHR2 (CRF-RB; CRF2; CRFR2; HM-CRF; CORTICOTROPIN RELEASING HORMONE RECEPTOR 2)
- - TAAR1 (TAR1; TRAR1; TRACE AMINE ASSOCIATED RECEPTOR 1)
- - ADA (ADENOSINE DEAMINASE)
- - MECP2 (AUTSX3; MRX16; MRX79; MRXS13; MRXSL; PPMX; METHYL-CPG BINDING PROTEIN 2)
- - APOE (APO-E; APOE4; LDLCQ5; APOLIPOPROTEIN E)
- - NFKB1 (CVID12; EBP-1; KBF1; NF-KB1; NF-KAPPA-B1; NF-KAPPAB; NFKB-P105; NFKB-P50; NFKAPPAB; NUCLEAR FACTOR KAPPA B SUBUNIT 1)
- - TPH2 (ADHD7; NTPH; TRYPTOPHAN HYDROXYLASE 2)
- - PRKAB1 (AMPK; HAMPKB; PROTEIN KINASE AMP-ACTIVATED NON-CATALYTIC SUBUNIT BETA 1)
- - PRKAA2 (AMPK; AMPK2; AMPKA2; PRKAA; PROTEIN KINASE AMP-ACTIVATED CATALYTIC SUBUNIT ALPHA 2)
- - PRKAA1 (AMPK; AMPKA1; PROTEIN KINASE AMP-ACTIVATED CATALYTIC SUBUNIT ALPHA 1)
- - MMP9 (CLG4B; GELB; MANDP2; MMP-9; MATRIX METALLOPEPTIDASE 9)
- - ADH7 (ADH4; ALCOHOL DEHYDROGENASE 7 CLASS IV , MU OR SIGMA POLYPEPTIDE)
- - MPO (MYELOPEROXIDASE)
- - VEGFA (MVCD1; VEGF; VASCULAR ENDOTHELIAL GROWTH FACTOR A)
- - HCRT (NRCLP1; PPOX; HYPOCRETIN NEUROPEPTIDE PRECURSOR)
- - CYP1A1 (AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX; CYTOCHROME P450 FAMILY 1 SUBFAMILY A MEMBER 1)
- - CHRNB3 (CHOLINERGIC RECEPTOR NICOTINIC BETA 3 SUBUNIT)
- - CHRNB2 (EFNL3; NACHRB2; CHOLINERGIC RECEPTOR NICOTINIC BETA 2 SUBUNIT)
- - VIP (PHM27; VASOACTIVE INTESTINAL PEPTIDE)
- - TACR1 (NK1R; NKIR; TAC1R; TACHYKININ RECEPTOR 1)
- - RGS9 (PERRS; RGS9L; REGULATOR OF G PROTEIN SIGNALING 9)
- - NR4A2 (HZF-3; NURR1; RNR1; TINUR; NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 2)
- - HCRTR2 (OX2R; HYPOCRETIN RECEPTOR 2)
- - GRM3 (GLUR3; GPRC1C; MGLUR3; MGLU3; GLUTAMATE METABOTROPIC RECEPTOR 3)
- - CYP1A2 (CP12; CYPIA2; P3-450; P450 PA ; CYTOCHROME P450 FAMILY 1 SUBFAMILY A MEMBER 2)
- - AP5B1 (AP-5; PP1030; ADAPTOR RELATED PROTEIN COMPLEX 5 SUBUNIT BETA 1)
- - PRKCG (PKC-GAMMA; PKCC; PKCG; PKCI 3 ; PKCGAMMA; SCA14; PROTEIN KINASE C GAMMA)
- - SIRT1 (SIR2; SIR2L1; SIR2ALPHA; SIRTUIN 1)
- - RGS4 (RGP4; SCZD9; REGULATOR OF G PROTEIN SIGNALING 4)
- - PTH (PTH1; PARATHYROID HORMONE)
- - PER2 (FASPS; FASPS1; PERIOD CIRCADIAN REGULATOR 2)
- - FGF2 (BFGF; FGF-2; FGFB; HBGF-2; FIBROBLAST GROWTH FACTOR 2)
- - ADH1A (ADH1; ALCOHOL DEHYDROGENASE 1A CLASS I , ALPHA POLYPEPTIDE)
- - GRM7 (GLUR7; GPRC1G; MGLU7; MGLUR7; PPP1R87; GLUTAMATE METABOTROPIC RECEPTOR 7)
- - ADH4 (ADH-2; HEL-S-4; ALCOHOL DEHYDROGENASE 4 CLASS II , PI POLYPEPTIDE)
- - NOS3 (ECNOS; ENOS; NITRIC OXIDE SYNTHASE 3)
- - ITGAM (CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; INTEGRIN SUBUNIT ALPHA M)
- - GSTM1 (GST1; GSTM1-1; GSTM1A-1A; GSTM1B-1B; GTH4; GTM1; GLUTATHIONE S-TRANSFERASE MU 1)
- - GPR55 (LPIR1; G PROTEIN-COUPLED RECEPTOR 55)
- - CYP2C19 (CPCJ; CYP2C; CYPIIC17; CYPIIC19; P450C2C; P450IIC19; CYTOCHROME P450 FAMILY 2 SUBFAMILY C MEMBER 19)
- - CCKBR ('xxCCK-B; CCK2R; GASR; CHOLECYSTOKININ B RECEPTOR)
- - TANK (I-TRAF; ITRAF; TRAF2; TRAF FAMILY MEMBER ASSOCIATED NFKB ACTIVATOR)
- - NCAM1 (CD56; MSK39; NCAM; NEURAL CELL ADHESION MOLECULE 1)
- - KCNJ6 (BIR1; GIRK-2; GIRK2; KATP-2; KATP2; KCNJ7; KIR3.2; KPLBS; HIGIRK2; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY J MEMBER 6)
- - HMGB1 (HMG-1; HMG1; HMG3; SBP-1; HIGH MOBILITY GROUP BOX 1)
- - HDAC2 (KDAC2; RPD3; YAF1; HISTONE DEACETYLASE 2)
- - CHRM2 (CHOLINERGIC RECEPTOR MUSCARINIC 2)
- - CCL5 (D17S136E; RANTES; SCYA5; SIS-DELTA; SISD; TCP228; EOCP; C-C MOTIF CHEMOKINE LIGAND 5)
- - ADCYAP1 (PACAP; ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 1)
- - SULT2A1 (DHEA-ST; DHEAS; ST2A1; ST2A3; HSTA; SULFOTRANSFERASE FAMILY 2A MEMBER 1)
- - PER1 (RIGUI; HPER; PERIOD CIRCADIAN REGULATOR 1)
- - MMP2 (CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1; MATRIX METALLOPEPTIDASE 2)
- - ARRB2 (ARB2; ARR2; BARR2; ARRESTIN BETA 2)
- - AGRP (AGRT; ASIP2; AGOUTI RELATED NEUROPEPTIDE)
- - SOD2 (IPO-B; IPOB; MNSOD; MVCD6; MN-SOD; SUPEROXIDE DISMUTASE 2)
- - MBP (MYELIN BASIC PROTEIN)
- - GAD2 (GAD65; GLUTAMATE DECARBOXYLASE 2)
- - EIF4EBP1 (4E-BP1; 4EBP1; BP-1; PHAS-I; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E BINDING PROTEIN 1)
- - CREM (CREM-2; ICER; HCREM-2; CAMP RESPONSIVE ELEMENT MODULATOR)
- - CHRNA6 (CHNRA6; CHOLINERGIC RECEPTOR NICOTINIC ALPHA 6 SUBUNIT)
- - ALK (CD246; NBLST3; ALK RECEPTOR TYROSINE KINASE)
- - UGT2B7 (UDPGT 2B7; UDPGT 2B9; UDPGT2B7; UDPGTH2; UDPGTH-2; UGT2B9; UDP GLUCURONOSYLTRANSFERASE FAMILY 2 MEMBER B7)
- - UGT1A4 (GNT1; HUG-BR2; UDPGT; UDPGT 1-4; UGT-1A; UGT-1D; UGT1; UGT1-01; UGT1-04; UGT1.1; UGT1.4; UGT1A; UGT1A1; UGT1A4S; UGT1D; HUG-BR1; UDP GLUCURONOSYLTRANSFERASE FAMILY 1 MEMBER A4)
- - SLC1A3 (EAAT1; GLAST; GLAST1; SOLUTE CARRIER FAMILY 1 MEMBER 3)
- - SHBG (TEBG; SEX HORMONE BINDING GLOBULIN)
- - PARP1 (ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; PADPRT-1; POLY ADP-RIBOSE POLYMERASE 1)
- - NLRP3 (AGTAVPRL; C1ORF7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; KEFH; NALP3; PYPAF1; NLR FAMILY PYRIN DOMAIN CONTAINING 3)
- - NFE2L2 (HEBP1; IMDDHH; NRF2; NUCLEAR FACTOR, ERYTHROID 2 LIKE 2)
- - IL1RN (DIRA; ICIL-1RA; IL-1RN; IL-1RA; IL-1RA3; IL1F3; IL1RA; IRAP; MVCD4; INTERLEUKIN 1 RECEPTOR ANTAGONIST)
- - GABPA (E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07; GA BINDING PROTEIN TRANSCRIPTION FACTOR SUBUNIT ALPHA)
- - FKBP5 (AIG6; FKBP51; FKBP54; PPIASE; PTG-10; FKBP PROLYL ISOMERASE 5)
- - ALDH1A1 (ALDC; ALDH-E1; ALDH1; ALDH11; HEL-9; HEL-S-53E; HEL12; PUMB1; RALDH1; ALDEHYDE DEHYDROGENASE 1 FAMILY MEMBER A1)
- - UGT1A6 (GNT1; HLUGP; HLUGP1; UDPGT; UDPGT 1-6; UGT-1A; UGT-1C; UGT-1E; UGT1; UGT1-01; UGT1-03; UGT1-05; UGT1.1; UGT1.3; UGT1.5; UGT1A; UGT1A1; UGT1A3; UGT1A5; UGT1A6S; UGT1C; UGT1E; UGT1F; HUG-BR1; UDP GLUCURONOSYLTRANSFERASE FAMILY 1 MEMBER A6)
- - SIGMAR1 (ALS16; DSMA2; OPRS1; SIG-1R; SR-BP; SR-BP1; SRBP; HSIGMAR1; SIGMA1R; SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)
- - RAC1 (MIG5; MRD48; RAC-1; TC-25; P21-RAC1; RAC FAMILY SMALL GTPASE 1)
- - P4HTM (EGLN4; HIFPH4; P4H-TM; 'PH-4; PHD4; PROLYL 4-HYDROXYLASE, TRANSMEMBRANE)
- - KRAS (C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-RAS; KI-RAS; KRAS1; KRAS2; RALD; RASK2; C-KI-RAS2; KRAS PROTO-ONCOGENE, GTPASE)
- - IL18 (IGIF; IL-18; IL-1G; IL1F4; INTERLEUKIN 18)
- - HTR3A (5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3; 5-HYDROXYTRYPTAMINE RECEPTOR 3A)
- - HSPA4 (APG-2; HEL-S-5A; HS24/P52; HSPH2; HSP70; HSP70RY; HEAT SHOCK PROTEIN FAMILY A HSP70 MEMBER 4)
- - FYN (P59-FYN; FYN PROTO-ONCOGENE, SRC FAMILY TYROSINE KINASE)
- - COL11A2 (DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3; COLLAGEN TYPE XI ALPHA 2 CHAIN)
- - UGT1A7 (GNT1; UDPGT; UDPGT 1-7; UGT-1A; UGT-1G; UGT1; UGT1-01; UGT1-07; UGT1.1; UGT1.7; UGT1A; UGT1A1; UGT1G; HUG-BR1; UDP GLUCURONOSYLTRANSFERASE FAMILY 1 MEMBER A7)
- - TRPA1 (ANKTM1; FEPS; FEPS1; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY A MEMBER 1)
- - STAT3 (ADMIO; ADMIO1; APRF; HIES; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3)
- - PRKCA (AAG6; PKC-ALPHA; PKCA; PKCI+/-; PKCALPHA; PRKACA; PROTEIN KINASE C ALPHA)
- - MTHFR (METHYLENETETRAHYDROFOLATE REDUCTASE)
- - GRK2 (ADRBK1; BARK1; BETA-ARK1; G PROTEIN-COUPLED RECEPTOR KINASE 2)
- - DNMT1 (ADCADN; CXXC9; DNMT; HSN1E; MCMT; M.HSAI; DNA METHYLTRANSFERASE 1)
- - UGT1A8 (GNT1; UDPGT; UDPGT 1-8; UGT-1A; UGT-1H; UGT1; UGT1-01; UGT1-08; UGT1.1; UGT1.8; UGT1A; UGT1A1; UGT1A8S; UGT1H; HUG-BR1; UDP GLUCURONOSYLTRANSFERASE FAMILY 1 MEMBER A8)
+- FOS (AP\ 1; C\ FOS; CFOS; FOS\ PROTO\ ONCOGENE,\ AP\ 1\ TRANSCRIPTION\ FACTOR\ SUBUNIT)
+ - BDNF (ANON2; BRAIN\ DERIVED\ NEUROTROPHIC\ FACTOR; BULN2)
+ - TH (DYT14; DYT5B; TYROSINE\ HYDROXYLASE; TYROSINEHYDROXYLASE)
+ - OPRM1 (LMOR; M\ OR\ 1; MOR1; OPIOID\ RECEPTOR\ MU\ 1; OPRM)
+ - CNR1 (CNRS1; PROTOCADHERIN\ ALPHA\ CLUSTER,\ COMPLEX\ LOCUS)
+ - DRD2 (D2DR; DOPAMINE\ RECEPTOR\ D2)
+ - CREB1 (CAMP\ RESPONSIVE\ ELEMENT\ BINDING\ PROTEIN\ 1; CREB; CREB\ 1)
+ - SLC6A4 (5\ HTT; 5\ HTTLPR; 5HTT; 5HTTLPR; HSERT; OCD1; SERT; SERT1; SOLUTE\ CARRIER\ FAMILY\ 6\ MEMBER\ 4)
+ - TNF (TNF\ ALPHA; TNFA; TNFALPHA; TNFSF2; TNLG1F; TUMOR\ NECROSIS\ FACTOR)
+ - CYP2B6 (CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; CYTOCHROME\ P450\ FAMILY\ 2\ SUBFAMILY\ B\ MEMBER\ 6; EFVM; IIB1; P450)
+ - NPY (NEUROPEPTIDE\ Y; NEUROPEPTIDEY; PYY4)
+ - GRM5 (GLUTAMATE\ METABOTROPIC\ RECEPTOR\ 5; GPRC1E; MGLU5; MGLUR5; PPP1R86)
+ - GRIN2B (EIEE27; GLUN2B; GLUTAMATE\ IONOTROPIC\ RECEPTOR\ NMDA\ TYPE\ SUBUNIT\ 2B; HNR3; MRD6; NMDAR2B; NR2B)
+ - HTR1A (5\ HT\ 1A; 5\ HT1A; 5\ HYDROXYTRYPTAMINE\ RECEPTOR\ 1A; 5HT1A; 5HT1A; ADRB2RL1; ADRBRL1; PFMCD)
+ - GRIA1 (GLUA1; GLUH1; GLUR1; GLURA; GLUTAMATE\ IONOTROPIC\ RECEPTOR\ AMPA\ TYPE\ SUBUNIT\ 1; HBGR1)
+ - ALDH2 (ALDEHYDE\ DEHYDROGENASE\ 2\ FAMILY\ MEMBER; ALDH\ E2; ALDHE2; ALDHI; ALDM)
+ - HTR2A (5\ HT2A; 5\ HYDROXYTRYPTAMINE\ RECEPTOR\ 2A; 5HT2A; HTR2)
+ - CRHR1 (CORTICOTROPIN\ RELEASING\ HORMONE\ RECEPTOR\ 1; CRF\ R; CRF\ R\ 1; CRF\ R1; CRF1; CRFR; CRFR\ 1; CRFR1; CRH\ R\ 1; CRH\ R1; CRHR; CRHR1L)
+ - GRM2 (GLUR2; GLUTAMATE\ METABOTROPIC\ RECEPTOR\ 2; GPRC1B; MGLU2; MGLUR2)
+ - CHRNA5 (CHOLINERGIC\ RECEPTOR\ NICOTINIC\ ALPHA\ 5\ SUBUNIT; LNCR2)
+ - IL6 (BSF\ 2; BSF2; IFN\ BETA\ 2; IFNB2; IL\ 6; INTERLEUKIN\ 6; INTERLEUKIN6)
+ - COMT (CATECHOL\ O\ METHYLTRANSFERASE; HEL\ S\ 98N)
+ - PDYN (ADCA; PENKB; PRODYNORPHIN; SCA23)
+ - FAAH1 (FAAH\ 1; FATTY\ ACID\ AMIDE\ HYDROLASE; PSAB)
+ - NPS (NEUROPEPTIDE\ S)
+ - MAPK3 (ERK\ 1; ERK1; ERT2; HS44KDAP; HUMKER1A; MITOGEN\ ACTIVATED\ PROTEIN\ KINASE\ 3; P44\ ERK1; P44\ MAPK; P44ERK1; P44ERK1; P44MAPK; P44MAPK; PRKM3)
+ - FOSB (AP\ 1; FOSB\ PROTO\ ONCOGENE,\ AP\ 1\ TRANSCRIPTION\ FACTOR\ SUBUNIT; G0S3; GOS3; GOSB)
+ - CRH (CORTICOTROPIN\ RELEASING\ HORMONE; CRH1)
+ - TLR4 (ARMD10; CD284; TLR\ 4; TOLL\ LIKE\ RECEPTOR\ 4)
+ - GRIA2 (GLUA2; GLUR\ 2; GLUR\ B; GLUR\ K2; GLUR2; GLUR2; GLURB; GLURB; GLURK2; GLUTAMATE\ IONOTROPIC\ RECEPTOR\ AMPA\ TYPE\ SUBUNIT\ 2; HBGR2)
+ - CYP2A6 (CPA6; CYP2A; CYP2A3; CYPIIA6; CYTOCHROME\ P450\ FAMILY\ 2\ SUBFAMILY\ A\ MEMBER\ 6; P450C2A; P450PB)
+ - HTR2C (5\ HT1C; 5\ HT2C; 5\ HTR2C; 5\ HYDROXYTRYPTAMINE\ RECEPTOR\ 2C; 5HT1C; 5HT2C; 5HTR2C; HTR1C)
+ - ADH1B (ADH2; ALCOHOL\ DEHYDROGENASE\ 1B\ CLASS\ I\ ,\ BETA\ POLYPEPTIDE; HEL\ S\ 117)
+ - DRD4 (D4DR; DOPAMINE\ RECEPTOR\ D4)
+ - ARC (ACTIVITY\ REGULATED\ CYTOSKELETON\ ASSOCIATED\ PROTEIN; ARG3.1; HARC)
+ - MAOA (BRNRS; MAO\ A; MONOAMINE\ OXIDASE\ A)
+ - CYP2E1 (CPE1; CYP2E; CYTOCHROME\ P450\ FAMILY\ 2\ SUBFAMILY\ E\ MEMBER\ 1; P450\ J; P450C2E; P450J)
+ - SLC1A2 (EAAT2; EIEE41; GLT\ 1; GLT1; HBGT; SOLUTE\ CARRIER\ FAMILY\ 1\ MEMBER\ 2)
+ - GRIN2A (EPND; FESD; GLUN2A; GLUTAMATE\ IONOTROPIC\ RECEPTOR\ NMDA\ TYPE\ SUBUNIT\ 2A; NMDAR2A; NR2A)
+ - POMC (OBAIRH; PROOPIOMELANOCORTIN)
+ - SLC6A3 (DAT1; PKDYS; PKDYS1; SOLUTE\ CARRIER\ FAMILY\ 6\ MEMBER\ 3)
+ - NGF (BETA\ NGF; BETANGF; HSAN5; NERVE\ GROWTH\ FACTOR; NGFB)
+ - DBH (DOPAMINE\ BETA\ HYDROXYLASE; ORTHYP1)
+ - PENK (PENK\ A; PENKA; PROENKEPHALIN)
+ - HTR1B (5\ HT\ 1B; 5\ HT\ 1D\ BETA; 5\ HT1B; 5\ HT1DB; 5\ HYDROXYTRYPTAMINE\ RECEPTOR\ 1B; 5HT1B; 5HT1DB; HTR1D2; HTR1DB)
+ - JUN (AP\ 1; C\ JUN; CJUN; CJUN; JUN\ PROTO\ ONCOGENE,\ AP\ 1\ TRANSCRIPTION\ FACTOR\ SUBUNIT)
+ - CASP3 (CASPASE\ 3; CASPASE3; CPP32; CPP32B; SCA\ 1; SCA1)
+ - CHRNA3 (BAIPRCK; CHOLINERGIC\ RECEPTOR\ NICOTINIC\ ALPHA\ 3\ SUBUNIT; LNCR2; NACHRA3; PAOD2)
+ - NEUROTENSIN (NMN\ 125; NMN125; NT/N; NTS1)
+ - NTRK2 (EIEE58; GP145\ TRKB; GP145TRKB; NEUROTROPHIC\ RECEPTOR\ TYROSINE\ KINASE\ 2; OBHD; TRK\ B; TRKB; TRKB)
+ - CAMK2G (CALCIUM/CALMODULIN\ DEPENDENT\ PROTEIN\ KINASE\ II\ GAMMA; CAMK; CAMK\ II; CAMKG; CAMKII; MRD59)
+ - TRPV1 (TRANSIENT\ RECEPTOR\ POTENTIAL\ CATION\ CHANNEL\ SUBFAMILY\ V\ MEMBER\ 1)
+ - CYP2D6 (CPD6; CYP2D; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID6; CYTOCHROME\ P450\ FAMILY\ 2\ SUBFAMILY\ D\ MEMBER\ 6; P450\ DB1; P450C2D; P450DB1)
+ - CORT (CORTISTATIN; CST\ 14; CST\ 17; CST\ 29; CST14; CST17; CST29)
+ - GFAP (ALXDRD; GLIAL\ FIBRILLARY\ ACIDIC\ PROTEIN)
+ - GABRA2 (EIEE78; GAMMA\ AMINOBUTYRIC\ ACID\ TYPE\ A\ RECEPTOR\ SUBUNIT\ ALPHA2)
+ - EGR1 (AT225; EARLY\ GROWTH\ RESPONSE\ 1; G0S30; KROX\ 24; KROX24; NGFI\ A; NGFIA; TIS8; ZIF\ 268; ZIF268; ZNF225)
+ - NOS1 (BNOS; IHPS1; N\ NOS; NC\ NOS; NCNOS; NITRIC\ OXIDE\ SYNTHASE\ 1; NNOS; NNOS)
+ - ANKK1 (ANKYRIN\ REPEAT\ AND\ KINASE\ DOMAIN\ CONTAINING\ 1; PKK2; SGK288)
+ - CYP3A4 (CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; CYTOCHROME\ P450\ FAMILY\ 3\ SUBFAMILY\ A\ MEMBER\ 4; NF\ 25; NF25; P450C3; P450PCN1)
+ - PCDHA4 (CNR1; CNRN1; CRNR1; PCDH\ ALPHA4; PCDHALPHA4; PROTOCADHERIN\ ALPHA\ 4)
+ - IL10 (CSIF; GVHDS; IL\ 10; IL10A; INTERLEUKIN\ 10; INTERLEUKIN10; TGIF)
+ - MTOR (FRAP; FRAP1; FRAP2; MECHANISTIC\ TARGET\ OF\ RAPAMYCIN\ KINASE; RAFT1; RAPT1)
+ - TRH (PRO\ TRH; PROTRH; THYROTROPIN\ RELEASING\ HORMONE)
+ - CHRNB4 (CHOLINERGIC\ RECEPTOR\ NICOTINIC\ BETA\ 4\ SUBUNIT)
+ - GRM1 (GLUTAMATE\ METABOTROPIC\ RECEPTOR\ 1; GPRC1A; MGLU1; MGLUR1; PPP1R85; SCA44; SCAR13)
+ - GDNF (ATF1; ATF2; GLIAL\ CELL\ DERIVED\ NEUROTROPHIC\ FACTOR; HFB1\ GDNF; HFB1GDNF; HSCR3)
+ - DRD1 (DADR; DOPAMINE\ RECEPTOR\ D1; DRD1A)
+ - GRIN1 (GLUN1; GLUTAMATE\ IONOTROPIC\ RECEPTOR\ NMDA\ TYPE\ SUBUNIT\ 1; MRD8; NDHMSD; NDHMSR; NMD\ R1; NMDA1; NMDAR1; NMDR1)
+ - BCHE (BCHED; BUTYRYLCHOLINESTERASE; CHE1; CHE2)
+ - CCL2 (C\ C\ MOTIF\ CHEMOKINE\ LIGAND\ 2; GDCF\ 2; GDCF2; HC11; HSMCR30; MCAF; MCP\ 1; MCP1; SCYA2; SMC\ CF; SMCCF)
+ - ADH1C (ADH3; ALCOHOL\ DEHYDROGENASE\ 1C\ CLASS\ I\ ,\ GAMMA\ POLYPEPTIDE)
+ - WARS1 (GAMMA\ 2; GAMMA2; HMN9; IFI53; IFP53; TRYPTOPHANYL\ TRNA\ SYNTHETASE\ 1; WARS)
+ - ADH4 (ADH\ 2; ADH2; ALCOHOL\ DEHYDROGENASE\ 4\ CLASS\ II\ ,\ PI\ POLYPEPTIDE; HEL\ S\ 4)
+ - PTGS2 (COX\ 2; COX2; GRIPGHS; HCOX\ 2; HCOX2; PGG/HS; PGHS\ 2; PGHS2; PHS\ 2; PHS2; PROSTAGLANDIN\ ENDOPEROXIDE\ SYNTHASE\ 2)
+ - HDAC9 (HD7B; HDAC; HDAC7; HDAC7B; HDAC9B; HDAC9FL; HDRP; HISTONE\ DEACETYLASE\ 9; MITR)
+ - RTN4 (NBLA00271; NBLA10545; NOGO; NSP\ CL; NSPCL; RETICULON\ 4; RETICULON4; RTN\ X; RTN4\ A; RTN4\ B1; RTN4\ B2; RTN4\ C; RTN4A; RTN4B1; RTN4B2; RTN4C; RTNX)
+ - PPP1R1B (DARPP\ 32; DARPP32; PROTEIN\ PHOSPHATASE\ 1\ REGULATORY\ INHIBITOR\ SUBUNIT\ 1B)
+ - PPARA (HPPAR; NR1C1; PEROXISOME\ PROLIFERATOR\ ACTIVATED\ RECEPTOR\ ALPHA; PPAR; PPARALPHA)
+ - BAX (BCL2\ ASSOCIATED\ X,\ APOPTOSIS\ REGULATOR; BCL2L4)
+ - OPRK1 (K\ OR\ 1; KOR\ 1; KOR1; OPIOID\ RECEPTOR\ KAPPA\ 1; OPRK)
+ - DRD3 (D3DR; DOPAMINE\ RECEPTOR\ D3; ETM1; FET1)
+ - BCL2 (BCL\ 2; BCL2; BCL2\ APOPTOSIS\ REGULATOR; PPP1R50)
+ - HOMER1 (HOMER; HOMER\ SCAFFOLD\ PROTEIN\ 1; HOMER1A; HOMER1B; HOMER1C; SYN47; VES\ 1; VES1)
+ - EGFR (EPIDERMAL\ GROWTH\ FACTOR\ RECEPTOR; ERBB; ERBB1; HER1; MENA; NISBD2; PIG61)
+ - ACHE (ACEE; ACETYLCHOLINESTERASE\ CARTWRIGHT\ BLOOD\ GROUP; ARACHE; N\ ACHE; NACHE)
+ - ADORA2A (A2AR; ADENOSINE\ A2A\ RECEPTOR; ADORA2; RDC8)
+ - ABCB1 (ABC20; ATP\ BINDING\ CASSETTE\ SUBFAMILY\ B\ MEMBER\ 1; CD243; CLCS; GP170; MDR1; P\ GP; PGY1)
+ - MGLL (HU\ K5; HUK5; MAGL; MONOGLYCERIDE\ LIPASE; MONOGLYCERIDELIPASE)
+ - CDK5 (CYCLIN\ DEPENDENT\ KINASE\ 5; LIS7; PSSALRE)
+ - PSENEN (ACNINV2; MDS033; MSTP064; PEN\ 2; PEN2; PRESENILIN\ ENHANCER,\ GAMMA\ SECRETASE\ SUBUNIT)
+ - SH2D3C (CHAT; NSP3; PRO34088; SH2\ DOMAIN\ CONTAINING\ 3C; SHEP1)
+ - IL1B (IL\ 1; IL1\ BETA; IL1BETA; IL1BETA; IL1F2; INTERLEUKIN\ 1\ BETA)
+ - CHAT (CHOACTASE; CHOLINE\ O\ ACETYLTRANSFERASE; CMS1A; CMS1A2; CMS6)
+ - CCL4 (ACT2; AT744.1; C\ C\ MOTIF\ CHEMOKINE\ LIGAND\ 4; G\ 26; HC21; LAG\ 1; LAG1; MIP\ 1\ BETA; MIP1B; MIP1B1; SCYA2; SCYA4)
+ - CALCA (CALC1; CALCITONIN\ RELATED\ POLYPEPTIDE\ ALPHA; CGRP; CGRP\ ALPHA; CGRP\ I; CGRP1; CGRPALPHA; CGRPI)
+ - S100A12 (CAAF1; CAGC; CGRP; MRP\ 6; MRP6; S100\ CALCIUM\ BINDING\ PROTEIN\ A12)
+ - OPRD1 (DOR1; OPIOID\ RECEPTOR\ DELTA\ 1; OPRD)
+ - JUNB (AP\ 1; JUNB\ PROTO\ ONCOGENE,\ AP\ 1\ TRANSCRIPTION\ FACTOR\ SUBUNIT)
+ - GSTM1 (GLUTATHIONE\ S\ TRANSFERASE\ MU\ 1; GST1; GSTM1\ 1; GSTM11; GSTM1A\ 1A; GSTM1A1A; GSTM1B\ 1B; GSTM1B1B; GTH4; GTM1; H\ B; MU\ 1)
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