From 3dba78248d81fc97d5347fa167828ba3a8f95cd8 Mon Sep 17 00:00:00 2001 From: Hao Chen Date: Tue, 21 May 2019 05:35:29 -0500 Subject: minor adj --- ratspub_keywords.py | 2 +- static/ratspub.png | Bin 258462 -> 298585 bytes templates/about.html | 3 +- templates/index.html | 16 ++-- topGene_symb_alias.txt | 200 +++++++++++++++++++++++++++++++++++++++++++++++++ 5 files changed, 211 insertions(+), 10 deletions(-) create mode 100644 topGene_symb_alias.txt diff --git a/ratspub_keywords.py b/ratspub_keywords.py index 0c7d0dd..8a23e73 100644 --- a/ratspub_keywords.py +++ b/ratspub_keywords.py @@ -1,7 +1,7 @@ addiction_d = {"reward":"reward|hedonic|incentive|intracranial self stimulation|ICSS|reinforcement|reinforcing|conditioned place preference|CPP|self administration|self administered|drug reinforced|operant|instrumental response", "aversion":"aversion|aversive|CTA|conditioned taste aversion", "withdrawal":"withdrawal", - "relapse":"relapse|reinstatement|craving|drug seeking|seeking|incubation", + "relapse":"relapse|reinstatement|craving|drug seeking|seeking", "sensitization":"sensitization", "addiction":"addiction|addictive|drug abuse|punishment|compulsive|escalation", "dependence":"dependence", diff --git a/static/ratspub.png b/static/ratspub.png index a031bc0..9fa0a49 100644 Binary files a/static/ratspub.png and b/static/ratspub.png differ diff --git a/templates/about.html b/templates/about.html index 4d944e9..ebd8554 100644 --- a/templates/about.html +++ b/templates/about.html @@ -2,7 +2,8 @@ {% extends "layout.html" %} {% block content %} -

About RatsPub ...

+

About RatsPub

+

RatsPub searches PubMed to find abstracts containing genes of interest and a list of curated addiction-related keywords. The abstracts corresponding to these returned PMIDs are then retrieve from a local archive of the PubMed. No limit on the date of publication is set. Each abstract is then broken down into sentences, which are then filtered by gene names and keywords. diff --git a/templates/index.html b/templates/index.html index 7df2a4e..f9a4fc1 100644 --- a/templates/index.html +++ b/templates/index.html @@ -7,21 +7,21 @@ -
-

- RatsPub searches PubMed to find sentences that contain the query terms (i.e., gene symbols) and drug addiction-related keywords. These gene-keyword relationships are presented as an interactive graph that can efficiently answer the question "What do we know about these genes and addiction?". Data from EBI GWAS catalog are also included in the search to better answer this question. + +

RatsPub searches PubMed to find sentences that contain the query terms (i.e., gene symbols) and drug addiction-related keywords. These gene-keyword relationships are presented as an interactive graph that can efficiently answer the question "What do we know about these genes and addiction?". Data from EBI GWAS catalog are also included in the search to better answer this question.

The graph has many interactive elements. For example, clicking gene names will launch a new search for sentences containing the target gene and 200 addiction-related genes. These results help to answer the question "Are there genes that can link my gene of interest to addiction?" + +

Up to 100 gene symbols can be searched at a time. Gene symbols can be separated by either a space or a semicolon. Gene alias will not be automatically included because the large number of false matches associated with gene synonyms retrieved from databases.

-
- - Up to 100 gene symbols can be searched at a time. Gene symbols can be separated by either a space or a semicolon. Gene alias will not be automatically included because the large number of false matches associated with gene synonyms retrieved from databases. -
+ + +

- Example: Rgma Nrxn3; Chrna3 + Example: Rgma Nrxn3 Chrna3

diff --git a/topGene_symb_alias.txt b/topGene_symb_alias.txt new file mode 100644 index 0000000..bf08e3f --- /dev/null +++ b/topGene_symb_alias.txt @@ -0,0 +1,200 @@ +CNR1 CNRS1; PROTOCADHERIN ALPHA CLUSTER, COMPLEX LOCUS +OPRM1 LMOR; M-OR-1; MOP; MOR; MOR1; OPRM; OPIOID RECEPTOR MU 1 +FOS C-FOS; P55; FOS PROTO-ONCOGENE, AP-1 TRANSCRIPTION FACTOR SUBUNIT +SLC6A3 DAT; DAT1; PKDYS; PKDYS1; SOLUTE CARRIER FAMILY 6 MEMBER 3 +CRH CRF; CRH1; CORTICOTROPIN RELEASING HORMONE +BDNF ANON2; BULN2; BRAIN DERIVED NEUROTROPHIC FACTOR +DRD2 D2DR; D2R; DOPAMINE RECEPTOR D2 +POMC ACTH; OBAIRH; PROOPIOMELANOCORTIN +CREB1 CREB; CREB-1; CAMP RESPONSIVE ELEMENT BINDING PROTEIN 1 +OPRK1 K-OR-1; KOR; KOR-1; OPRK; OPIOID RECEPTOR KAPPA 1 +TNF TNF-ALPHA; TNFA; TNFSF2; TNLG1F; TUMOR NECROSIS FACTOR +MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; P41; P41MAPK; P42-MAPK; MITOGEN-ACTIVATED PROTEIN KINASE 1 +SLC6A4 5-HTT; 5-HTTLPR; 5HTT; OCD1; SERT; SERT1; HSERT; SOLUTE CARRIER FAMILY 6 MEMBER 4 +CNR2 CB-2; CB2; CX5; CANNABINOID RECEPTOR 2 +OXT OT-NPI; OXT-NPI; OXYTOCIN; NEUROPHYSIN I PREPROPEPTIDE +GRM5 GPRC1E; MGLUR5; PPP1R86; MGLU5; GLUTAMATE METABOTROPIC RECEPTOR 5 +NPY PYY4; NEUROPEPTIDE Y +NOS1 IHPS1; N-NOS; NC-NOS; NOS; BNOS; NNOS; NITRIC OXIDE SYNTHASE 1 +ALDH2 ALDH-E2; ALDHI; ALDM; ALDEHYDE DEHYDROGENASE 2 FAMILY MEMBER +PNOC NOP; OFQ; PPNOC; PREPRONOCICEPTIN +GRIA1 GLUH1; GLUR1; GLURA; GLUA1; HBGR1; GLUTAMATE IONOTROPIC RECEPTOR AMPA TYPE SUBUNIT 1 +CHRNA5 LNCR2; CHOLINERGIC RECEPTOR NICOTINIC ALPHA 5 SUBUNIT +GRIN2B EIEE27; GLUN2B; MRD6; NMDAR2B; NR2B; NR3; HNR3; GLUTAMATE IONOTROPIC RECEPTOR NMDA TYPE SUBUNIT 2B +IL6 BSF-2; BSF2; HGF; HSF; IFN-BETA-2; IFNB2; IL-6; INTERLEUKIN 6 +PDYN ADCA; PENKB; SCA23; PRODYNORPHIN +GRM2 GLUR2; GPRC1B; MGLUR2; MGLU2; GLUTAMATE METABOTROPIC RECEPTOR 2 +HTR1A 5-HT-1A; 5-HT1A; 5HT1A; ADRB2RL1; ADRBRL1; PFMCD; 5-HYDROXYTRYPTAMINE RECEPTOR 1A +COMT HEL-S-98N; CATECHOL-O-METHYLTRANSFERASE +CRHR1 CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1L; CORTICOTROPIN RELEASING HORMONE RECEPTOR 1 +GGT1 CD224; D22S672; D22S732; GGT; GGT 1; GGTD; GAMMA-GLUTAMYLTRANSFERASE 1 +MAPK3 ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; P44-ERK1; P44-MAPK; MITOGEN-ACTIVATED PROTEIN KINASE 3 +CYP2A6 CPA6; CYP2A; CYP2A3; CYPIIA6; P450C2A; P450PB; CYTOCHROME P450 FAMILY 2 SUBFAMILY A MEMBER 6 +ADH1B ADH2; HEL-S-117; ALCOHOL DEHYDROGENASE 1B CLASS I , BETA POLYPEPTIDE +GRIN1 GLUN1; MRD8; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1; GLUTAMATE IONOTROPIC RECEPTOR NMDA TYPE SUBUNIT 1 +DRD4 D4DR; DOPAMINE RECEPTOR D4 +NPS NEUROPEPTIDE S +HTR2A 5-HT2A; HTR2; 5-HYDROXYTRYPTAMINE RECEPTOR 2A +GAD1 CPSQ1; GAD; SCP; GLUTAMATE DECARBOXYLASE 1 +PENK PENK-A; PROENKEPHALIN +GRIA2 GLUR2; GLURB; GLUA2; GLUR-K2; HBGR2; GLUTAMATE IONOTROPIC RECEPTOR AMPA TYPE SUBUNIT 2 +TLR4 ARMD10; CD284; TLR-4; TOLL LIKE RECEPTOR 4 +MAOA BRNRS; MAO-A; MONOAMINE OXIDASE A +ARC ARG3.1; HARC; ACTIVITY REGULATED CYTOSKELETON ASSOCIATED PROTEIN +CHRNA3 LNCR2; NACHRA3; PAOD2; CHOLINERGIC RECEPTOR NICOTINIC ALPHA 3 SUBUNIT +FOSB G0S3; GOS3; GOSB; FOSB PROTO-ONCOGENE, AP-1 TRANSCRIPTION FACTOR SUBUNIT +CYP2E1 CPE1; CYP2E; P450-J; P450C2E; CYTOCHROME P450 FAMILY 2 SUBFAMILY E MEMBER 1 +TRPV1 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 1 +IFNA1 IFL; IFN; IFN-ALPHA; IFN-ALPHAD; IFNA13; IFNA@; INTERFERON ALPHA 1 +HTR2C 5-HT1C; 5-HT2C; 5-HTR2C; 5HTR2C; HTR1C; 5-HYDROXYTRYPTAMINE RECEPTOR 2C +DBH ORTHYP1; DOPAMINE BETA-HYDROXYLASE +NGF BETA-NGF; HSAN5; NGFB; NERVE GROWTH FACTOR +GABRA2 GAMMA-AMINOBUTYRIC ACID TYPE A RECEPTOR ALPHA2 SUBUNIT +NTRK2 EIEE58; GP145-TRKB; OBHD; TRKB; TRK-B; NEUROTROPHIC RECEPTOR TYROSINE KINASE 2 +SLC1A2 EAAT2; EIEE41; GLT-1; HBGT; SOLUTE CARRIER FAMILY 1 MEMBER 2 +GRIN2A EPND; FESD; GLUN2A; LKS; NMDAR2A; NR2A; GLUTAMATE IONOTROPIC RECEPTOR NMDA TYPE SUBUNIT 2A +CRP PTX1; C-REACTIVE PROTEIN +HTR1B 5-HT-1B; 5-HT-1D-BETA; 5-HT1B; 5-HT1DB; HTR1D2; HTR1DB; 5-HYDROXYTRYPTAMINE RECEPTOR 1B +ANKK1 PKK2; SGK288; ANKYRIN REPEAT AND KINASE DOMAIN CONTAINING 1 +OPRD1 DOP; DOR1; OPRD; OPIOID RECEPTOR DELTA 1 +GFAP ALXDRD; GLIAL FIBRILLARY ACIDIC PROTEIN +CHRNB4 CHOLINERGIC RECEPTOR NICOTINIC BETA 4 SUBUNIT +CALCA CALC1; CGRP; CGRP-I; CGRP1; PCT; CALCITONIN RELATED POLYPEPTIDE ALPHA +IL10 CSIF; GVHDS; IL-10; IL10A; TGIF; INTERLEUKIN 10 +JUN AP1; C-JUN; JUN PROTO-ONCOGENE, AP-1 TRANSCRIPTION FACTOR SUBUNIT +PSENEN ACNINV2; MDS033; MSTP064; PEN-2; PEN2; PRESENILIN ENHANCER, GAMMA-SECRETASE SUBUNIT +PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; HCOX-2; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 2 +CYP3A4 CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450C3; P450PCN1; CYTOCHROME P450 FAMILY 3 SUBFAMILY A MEMBER 4 +ADH1C ADH3; ALCOHOL DEHYDROGENASE 1C CLASS I , GAMMA POLYPEPTIDE +GDNF ATF1; ATF2; HFB1-GDNF; HSCR3; GLIAL CELL DERIVED NEUROTROPHIC FACTOR +GRM1 GPRC1A; MGLU1; MGLUR1; PPP1R85; SCA44; SCAR13; GLUTAMATE METABOTROPIC RECEPTOR 1 +DRD1 DADR; DRD1A; DOPAMINE RECEPTOR D1 +MTOR FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS; MECHANISTIC TARGET OF RAPAMYCIN KINASE +BCHE BCHED; CHE1; CHE2; BUTYRYLCHOLINESTERASE +PPARA NR1C1; PPAR; PPARALPHA; HPPAR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA +TRH PRO-TRH; THYROTROPIN RELEASING HORMONE +OPRL1 KOR-3; NOCIR; NOPR; ORL1; OPIOID RELATED NOCICEPTIN RECEPTOR 1 +IL2 IL-2; TCGF; INTERLEUKIN 2 +RTN4 NOGO; NSP; NSP-CL; NBLA00271; NBLA10545; RTN-X; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C; RETICULON 4 +PPP1R1B DARPP-32; DARPP32; PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 1B +DRD3 D3DR; ETM1; FET1; DOPAMINE RECEPTOR D3 +CYP2B6 CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; CYTOCHROME P450 FAMILY 2 SUBFAMILY B MEMBER 6 +ABCB1 ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1; ATP BINDING CASSETTE SUBFAMILY B MEMBER 1 +MGLL HU-K5; HUK5; MAGL; MGL; MONOGLYCERIDE LIPASE +CCL2 GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF; C-C MOTIF CHEMOKINE LIGAND 2 +NOS2 HEP-NOS; INOS; NOS2A; NITRIC OXIDE SYNTHASE 2 +EGFR ERBB; ERBB1; HER1; NISBD2; PIG61; MENA; EPIDERMAL GROWTH FACTOR RECEPTOR +HOMER1 HOMER; HOMER1A; HOMER1B; HOMER1C; SYN47; VES-1; HOMER SCAFFOLD PROTEIN 1 +BCL2 BCL-2; PPP1R50; BCL2 APOPTOSIS REGULATOR +PLAT T-PA; TPA; PLASMINOGEN ACTIVATOR, TISSUE TYPE +IL1B IL-1; IL1-BETA; IL1F2; INTERLEUKIN 1 BETA +HCRTR1 OX1R; HYPOCRETIN RECEPTOR 1 +CDK5 LIS7; PSSALRE; CYCLIN DEPENDENT KINASE 5 +ADA2 ADGF; CECR1; IDGFL; PAN; SNEDS; VAIHS; ADENOSINE DEAMINASE 2 +CHAT CHOACTASE; CMS1A; CMS1A2; CMS6; CHOLINE O-ACETYLTRANSFERASE +MAP2K7 JNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4; MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7 +IL4 BCGF-1; BCGF1; BSF-1; BSF1; IL-4; INTERLEUKIN 4 +BAX BCL2L4; BCL2 ASSOCIATED X, APOPTOSIS REGULATOR +SLC18A2 PKDYS2; SVAT; SVMT; VAT2; VMAT2; SOLUTE CARRIER FAMILY 18 MEMBER A2 +MAPK8 JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1C; MITOGEN-ACTIVATED PROTEIN KINASE 8 +ADORA2A A2AR; ADORA2; RDC8; ADENOSINE A2A RECEPTOR +PIK3CD APDS; IMD14; P110DELTA; PI3K; P110D; PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA +CHRNA4 BFNC; EBN1; NACHRA4; NACRA4; CHOLINERGIC RECEPTOR NICOTINIC ALPHA 4 SUBUNIT +SRC SRC1; THC6; C-SRC; P60-SRC; SRC PROTO-ONCOGENE, NON-RECEPTOR TYROSINE KINASE +NPFF FMRFAL; NEUROPEPTIDE FF-AMIDE PEPTIDE PRECURSOR +HOMER2 ACPD; DFNA68; HOMER-2; VESL-2; HOMER SCAFFOLD PROTEIN 2 +EGR1 AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225; EARLY GROWTH RESPONSE 1 +ACHE ACEE; ARACHE; N-ACHE; ACETYLCHOLINESTERASE CARTWRIGHT BLOOD GROUP +NKS1 'EC-1; NATURAL KILLER CELL SUSCEPTIBILITY 1 +GNRH1 GNRH; LHRH; LNRH; GONADOTROPIN RELEASING HORMONE 1 +EGF HOMG4; EPIDERMAL GROWTH FACTOR +CRHR2 CRF-RB; CRF2; CRFR2; HM-CRF; CORTICOTROPIN RELEASING HORMONE RECEPTOR 2 +TAAR1 TAR1; TRAR1; TRACE AMINE ASSOCIATED RECEPTOR 1 +ADA ADENOSINE DEAMINASE +MECP2 AUTSX3; MRX16; MRX79; MRXS13; MRXSL; PPMX; METHYL-CPG BINDING PROTEIN 2 +APOE APO-E; APOE4; LDLCQ5; APOLIPOPROTEIN E +NFKB1 CVID12; EBP-1; KBF1; NF-KB1; NF-KAPPA-B1; NF-KAPPAB; NFKB-P105; NFKB-P50; NFKAPPAB; NUCLEAR FACTOR KAPPA B SUBUNIT 1 +TPH2 ADHD7; NTPH; TRYPTOPHAN HYDROXYLASE 2 +PRKAB1 AMPK; HAMPKB; PROTEIN KINASE AMP-ACTIVATED NON-CATALYTIC SUBUNIT BETA 1 +PRKAA2 AMPK; AMPK2; AMPKA2; PRKAA; PROTEIN KINASE AMP-ACTIVATED CATALYTIC SUBUNIT ALPHA 2 +PRKAA1 AMPK; AMPKA1; PROTEIN KINASE AMP-ACTIVATED CATALYTIC SUBUNIT ALPHA 1 +MMP9 CLG4B; GELB; MANDP2; MMP-9; MATRIX METALLOPEPTIDASE 9 +ADH7 ADH4; ALCOHOL DEHYDROGENASE 7 CLASS IV , MU OR SIGMA POLYPEPTIDE +MPO MYELOPEROXIDASE +VEGFA MVCD1; VEGF; VASCULAR ENDOTHELIAL GROWTH FACTOR A +HCRT NRCLP1; PPOX; HYPOCRETIN NEUROPEPTIDE PRECURSOR +CYP1A1 AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX; CYTOCHROME P450 FAMILY 1 SUBFAMILY A MEMBER 1 +CHRNB3 CHOLINERGIC RECEPTOR NICOTINIC BETA 3 SUBUNIT +CHRNB2 EFNL3; NACHRB2; CHOLINERGIC RECEPTOR NICOTINIC BETA 2 SUBUNIT +VIP PHM27; VASOACTIVE INTESTINAL PEPTIDE +TACR1 NK1R; NKIR; TAC1R; TACHYKININ RECEPTOR 1 +RGS9 PERRS; RGS9L; REGULATOR OF G PROTEIN SIGNALING 9 +NR4A2 HZF-3; NURR1; RNR1; TINUR; NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 2 +HCRTR2 OX2R; HYPOCRETIN RECEPTOR 2 +GRM3 GLUR3; GPRC1C; MGLUR3; MGLU3; GLUTAMATE METABOTROPIC RECEPTOR 3 +CYP1A2 CP12; CYPIA2; P3-450; P450 PA ; CYTOCHROME P450 FAMILY 1 SUBFAMILY A MEMBER 2 +AP5B1 AP-5; PP1030; ADAPTOR RELATED PROTEIN COMPLEX 5 SUBUNIT BETA 1 +PRKCG PKC-GAMMA; PKCC; PKCG; PKCI 3 ; PKCGAMMA; SCA14; PROTEIN KINASE C GAMMA +SIRT1 SIR2; SIR2L1; SIR2ALPHA; SIRTUIN 1 +RGS4 RGP4; SCZD9; REGULATOR OF G PROTEIN SIGNALING 4 +PTH PTH1; PARATHYROID HORMONE +PER2 FASPS; FASPS1; PERIOD CIRCADIAN REGULATOR 2 +FGF2 BFGF; FGF-2; FGFB; HBGF-2; FIBROBLAST GROWTH FACTOR 2 +ADH1A ADH1; ALCOHOL DEHYDROGENASE 1A CLASS I , ALPHA POLYPEPTIDE +GRM7 GLUR7; GPRC1G; MGLU7; MGLUR7; PPP1R87; GLUTAMATE METABOTROPIC RECEPTOR 7 +ADH4 ADH-2; HEL-S-4; ALCOHOL DEHYDROGENASE 4 CLASS II , PI POLYPEPTIDE +NOS3 ECNOS; ENOS; NITRIC OXIDE SYNTHASE 3 +ITGAM CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; INTEGRIN SUBUNIT ALPHA M +GSTM1 GST1; GSTM1-1; GSTM1A-1A; GSTM1B-1B; GTH4; GTM1; GLUTATHIONE S-TRANSFERASE MU 1 +GPR55 LPIR1; G PROTEIN-COUPLED RECEPTOR 55 +CYP2C19 CPCJ; CYP2C; CYPIIC17; CYPIIC19; P450C2C; P450IIC19; CYTOCHROME P450 FAMILY 2 SUBFAMILY C MEMBER 19 +CCKBR 'xxCCK-B; CCK2R; GASR; CHOLECYSTOKININ B RECEPTOR +TANK I-TRAF; ITRAF; TRAF2; TRAF FAMILY MEMBER ASSOCIATED NFKB ACTIVATOR +NCAM1 CD56; MSK39; NCAM; NEURAL CELL ADHESION MOLECULE 1 +KCNJ6 BIR1; GIRK-2; GIRK2; KATP-2; KATP2; KCNJ7; KIR3.2; KPLBS; HIGIRK2; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY J MEMBER 6 +HMGB1 HMG-1; HMG1; HMG3; SBP-1; HIGH MOBILITY GROUP BOX 1 +HDAC2 KDAC2; RPD3; YAF1; HISTONE DEACETYLASE 2 +CHRM2 CHOLINERGIC RECEPTOR MUSCARINIC 2 +CCL5 D17S136E; RANTES; SCYA5; SIS-DELTA; SISD; TCP228; EOCP; C-C MOTIF CHEMOKINE LIGAND 5 +ADCYAP1 PACAP; ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 1 +SULT2A1 DHEA-ST; DHEAS; ST2A1; ST2A3; HSTA; SULFOTRANSFERASE FAMILY 2A MEMBER 1 +PER1 RIGUI; HPER; PERIOD CIRCADIAN REGULATOR 1 +MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1; MATRIX METALLOPEPTIDASE 2 +ARRB2 ARB2; ARR2; BARR2; ARRESTIN BETA 2 +AGRP AGRT; ASIP2; AGOUTI RELATED NEUROPEPTIDE +SOD2 IPO-B; IPOB; MNSOD; MVCD6; MN-SOD; SUPEROXIDE DISMUTASE 2 +MBP MYELIN BASIC PROTEIN +GAD2 GAD65; GLUTAMATE DECARBOXYLASE 2 +EIF4EBP1 4E-BP1; 4EBP1; BP-1; PHAS-I; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E BINDING PROTEIN 1 +CREM CREM-2; ICER; HCREM-2; CAMP RESPONSIVE ELEMENT MODULATOR +CHRNA6 CHNRA6; CHOLINERGIC RECEPTOR NICOTINIC ALPHA 6 SUBUNIT +ALK CD246; NBLST3; ALK RECEPTOR TYROSINE KINASE +UGT2B7 UDPGT 2B7; UDPGT 2B9; UDPGT2B7; UDPGTH2; UDPGTH-2; UGT2B9; UDP GLUCURONOSYLTRANSFERASE FAMILY 2 MEMBER B7 +UGT1A4 GNT1; HUG-BR2; UDPGT; UDPGT 1-4; UGT-1A; UGT-1D; UGT1; UGT1-01; UGT1-04; UGT1.1; UGT1.4; UGT1A; UGT1A1; UGT1A4S; UGT1D; HUG-BR1; UDP GLUCURONOSYLTRANSFERASE FAMILY 1 MEMBER A4 +SLC1A3 EAAT1; GLAST; GLAST1; SOLUTE CARRIER FAMILY 1 MEMBER 3 +SHBG TEBG; SEX HORMONE BINDING GLOBULIN +PARP1 ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; PADPRT-1; POLY ADP-RIBOSE POLYMERASE 1 +NLRP3 AGTAVPRL; C1ORF7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; KEFH; NALP3; PYPAF1; NLR FAMILY PYRIN DOMAIN CONTAINING 3 +NFE2L2 HEBP1; IMDDHH; NRF2; NUCLEAR FACTOR, ERYTHROID 2 LIKE 2 +IL1RN DIRA; ICIL-1RA; IL-1RN; IL-1RA; IL-1RA3; IL1F3; IL1RA; IRAP; MVCD4; INTERLEUKIN 1 RECEPTOR ANTAGONIST +GABPA E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07; GA BINDING PROTEIN TRANSCRIPTION FACTOR SUBUNIT ALPHA +FKBP5 AIG6; FKBP51; FKBP54; PPIASE; PTG-10; FKBP PROLYL ISOMERASE 5 +ALDH1A1 ALDC; ALDH-E1; ALDH1; ALDH11; HEL-9; HEL-S-53E; HEL12; PUMB1; RALDH1; ALDEHYDE DEHYDROGENASE 1 FAMILY MEMBER A1 +UGT1A6 GNT1; HLUGP; HLUGP1; UDPGT; UDPGT 1-6; UGT-1A; UGT-1C; UGT-1E; UGT1; UGT1-01; UGT1-03; UGT1-05; UGT1.1; UGT1.3; UGT1.5; UGT1A; UGT1A1; UGT1A3; UGT1A5; UGT1A6S; UGT1C; UGT1E; UGT1F; HUG-BR1; UDP GLUCURONOSYLTRANSFERASE FAMILY 1 MEMBER A6 +SIGMAR1 ALS16; DSMA2; OPRS1; SIG-1R; SR-BP; SR-BP1; SRBP; HSIGMAR1; SIGMA1R; SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1 +RAC1 MIG5; MRD48; RAC-1; TC-25; P21-RAC1; RAC FAMILY SMALL GTPASE 1 +P4HTM EGLN4; HIFPH4; P4H-TM; 'PH-4; PHD4; PROLYL 4-HYDROXYLASE, TRANSMEMBRANE +KRAS C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-RAS; KI-RAS; KRAS1; KRAS2; RALD; RASK2; C-KI-RAS2; KRAS PROTO-ONCOGENE, GTPASE +IL18 IGIF; IL-18; IL-1G; IL1F4; INTERLEUKIN 18 +HTR3A 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3; 5-HYDROXYTRYPTAMINE RECEPTOR 3A +HSPA4 APG-2; HEL-S-5A; HS24/P52; HSPH2; HSP70; HSP70RY; HEAT SHOCK PROTEIN FAMILY A HSP70 MEMBER 4 +FYN P59-FYN; FYN PROTO-ONCOGENE, SRC FAMILY TYROSINE KINASE +COL11A2 DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3; COLLAGEN TYPE XI ALPHA 2 CHAIN +UGT1A7 GNT1; UDPGT; UDPGT 1-7; UGT-1A; UGT-1G; UGT1; UGT1-01; UGT1-07; UGT1.1; UGT1.7; UGT1A; UGT1A1; UGT1G; HUG-BR1; UDP GLUCURONOSYLTRANSFERASE FAMILY 1 MEMBER A7 +TRPA1 ANKTM1; FEPS; FEPS1; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY A MEMBER 1 +STAT3 ADMIO; ADMIO1; APRF; HIES; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 +PRKCA AAG6; PKC-ALPHA; PKCA; PKCI+/-; PKCALPHA; PRKACA; PROTEIN KINASE C ALPHA +MTHFR METHYLENETETRAHYDROFOLATE REDUCTASE +GRK2 ADRBK1; BARK1; BETA-ARK1; G PROTEIN-COUPLED RECEPTOR KINASE 2 +DNMT1 ADCADN; CXXC9; DNMT; HSN1E; MCMT; M.HSAI; DNA METHYLTRANSFERASE 1 +UGT1A8 GNT1; UDPGT; UDPGT 1-8; UGT-1A; UGT-1H; UGT1; UGT1-01; UGT1-08; UGT1.1; UGT1.8; UGT1A; UGT1A1; UGT1A8S; UGT1H; HUG-BR1; UDP GLUCURONOSYLTRANSFERASE FAMILY 1 MEMBER A8 -- cgit v1.2.3